메뉴 건너뛰기




Volumn 293, Issue , 2005, Pages 303-326

Phenotypic and functional differences between human CD4 +CD25+ and type 1 regulatory T cells

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; COLECALCIFEROL; DESMOGLEIN; GAMMA INTERFERON; GROWTH FACTOR; INTERLEUKIN 10; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; MEMBRANE COFACTOR PROTEIN; PROTEASOME INHIBITOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 20344372648     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/3-540-27702-1_14     Document Type: Review
Times cited : (71)

References (116)
  • 1
    • 10744227590 scopus 로고    scopus 로고
    • Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens
    • Aandahl EM, Michaelsson J, Moretto WJ, Hecht FM, Nixon DF (2004) Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens. J Virol 78:2454-2459
    • (2004) J Virol , vol.78 , pp. 2454-2459
    • Aandahl, E.M.1    Michaelsson, J.2    Moretto, W.J.3    Hecht, F.M.4    Nixon, D.F.5
  • 2
    • 1242295281 scopus 로고    scopus 로고
    • Pharmacological induction of tolerogenic dendritic cells and regulatory T cells
    • Adorini L, Giarratana N, Penna G (2004) Pharmacological induction of tolerogenic dendritic cells and regulatory T cells. Semin Immunol 16:127-134
    • (2004) Semin Immunol , vol.16 , pp. 127-134
    • Adorini, L.1    Giarratana, N.2    Penna, G.3
  • 3
    • 0034890907 scopus 로고    scopus 로고
    • Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen
    • Akbari O, DeKruyff RH, Umetsu DT (2001) Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nat Immunol 2:725-731
    • (2001) Nat Immunol , vol.2 , pp. 725-731
    • Akbari, O.1    DeKruyff, R.H.2    Umetsu, D.T.3
  • 6
    • 0041589414 scopus 로고    scopus 로고
    • Human CD4+ CD25+ regulatory T cells suppress NKT cell functions
    • Azuma T, Takahashi T, Kunisato A, Kitamura T, Hirai H (2003) Human CD4+ CD25+ regulatory T cells suppress NKT cell functions. Cancer Res 63:4516-4520
    • (2003) Cancer Res , vol.63 , pp. 4516-4520
    • Azuma, T.1    Takahashi, T.2    Kunisato, A.3    Kitamura, T.4    Hirai, H.5
  • 7
    • 0028158319 scopus 로고
    • High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells
    • Bacchetta R, Bigler M, Touraine JL, Parkman R, Tovo PA, Abrams J, de Waal Malefyt R, de Vries JE, Roncarolo MG (1994) High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells. J Exp Med 179:493-502
    • (1994) J Exp Med , vol.179 , pp. 493-502
    • Bacchetta, R.1    Bigler, M.2    Touraine, J.L.3    Parkman, R.4    Tovo, P.A.5    Abrams, J.6    De Waal Malefyt, R.7    De Vries, J.E.8    Roncarolo, M.G.9
  • 8
    • 0036687184 scopus 로고    scopus 로고
    • Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines
    • Bacchetta R, Sartirana C, Levings MK, Bordignon C, Narula S, Roncarolo MG (2002) Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines. Eur J Immunol 32:2237-2245
    • (2002) Eur J Immunol , vol.32 , pp. 2237-2245
    • Bacchetta, R.1    Sartirana, C.2    Levings, M.K.3    Bordignon, C.4    Narula, S.5    Roncarolo, M.G.6
  • 11
    • 11244291391 scopus 로고    scopus 로고
    • Functional defect of regulatory CD4+CD25+ T cells in the thymus of patients with autoimmune Myasthenia Gravis
    • e-pub Sept. 28 DOI 15454488
    • Balandina A, Lecart S, Dartevelle P, Saoudi A, Berrih-Aknin S (2004) Functional defect of regulatory CD4+CD25+ T cells in the thymus of patients with autoimmune Myasthenia Gravis. Blood 105:735-741; e-pub Sept. 28 DOI 15454488
    • (2004) Blood , vol.105 , pp. 735-741
    • Balandina, A.1    Lecart, S.2    Dartevelle, P.3    Saoudi, A.4    Berrih-Aknin, S.5
  • 12
    • 0037018104 scopus 로고    scopus 로고
    • In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
    • Barrat FJ, Cua DJ, Boonstra A, Richards DF, Crain C, Savelkoul HF, de Waal-Malefyt R, Coffman RL, Hawrylowicz CM, O'Garra A (2002) In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med 195:603-616
    • (2002) J Exp Med , vol.195 , pp. 603-616
    • Barrat, F.J.1    Cua, D.J.2    Boonstra, A.3    Richards, D.F.4    Crain, C.5    Savelkoul, H.F.6    De Waal-Malefyt, R.7    Coffman, R.L.8    Hawrylowicz, C.M.9    O'Garra, A.10
  • 14
    • 2242423605 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
    • Belkaid Y, Piccirillo CA, Mendez S, Shevach EM, Sacks DL (2002) CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature 420:502-507
    • (2002) Nature , vol.420 , pp. 502-507
    • Belkaid, Y.1    Piccirillo, C.A.2    Mendez, S.3    Shevach, E.M.4    Sacks, D.L.5
  • 15
    • 0037391766 scopus 로고    scopus 로고
    • Human CD4+CD25+ T cells derived from the majority of atopic donors are able to suppress TH1 and TH2 cytokine production
    • Bellinghausen I, Klostermann B, Knop J, Saloga J (2003) Human CD4+CD25+ T cells derived from the majority of atopic donors are able to suppress TH1 and TH2 cytokine production. J Allergy Clin Immunol 111:862-868
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 862-868
    • Bellinghausen, I.1    Klostermann, B.2    Knop, J.3    Saloga, J.4
  • 19
    • 0348013075 scopus 로고    scopus 로고
    • Human CD4+CD25+ regulatory cells have marked and sustained effects on CD8+ T cell activation
    • Camara NO, Sebille F, Lechler RI (2003) Human CD4+CD25+ regulatory cells have marked and sustained effects on CD8+ T cell activation. Eur J Immunol 33:3473-3483
    • (2003) Eur J Immunol , vol.33 , pp. 3473-3483
    • Camara, N.O.1    Sebille, F.2    Lechler, R.I.3
  • 20
    • 0037261145 scopus 로고    scopus 로고
    • Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis
    • Cao D, Malmstrom V, Baecher-Allan C, Hafler D, Klareskog L, Trollmo C (2003) Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis. Eur J Immunol 33:215-223
    • (2003) Eur J Immunol , vol.33 , pp. 215-223
    • Cao, D.1    Malmstrom, V.2    Baecher-Allan, C.3    Hafler, D.4    Klareskog, L.5    Trollmo, C.6
  • 21
    • 0345016451 scopus 로고    scopus 로고
    • Human CD25+ regulatory T cells maintain immune tolerance to nickel in healthy, nonallergic individuals
    • Cavani A, Nasorri F, Ottaviani C, Sebastiani S, De Pita O, Girolomoni G (2003) Human CD25+ regulatory T cells maintain immune tolerance to nickel in healthy, nonallergic individuals. J Immunol 171:5760-5768
    • (2003) J Immunol , vol.171 , pp. 5760-5768
    • Cavani, A.1    Nasorri, F.2    Ottaviani, C.3    Sebastiani, S.4    De Pita, O.5    Girolomoni, G.6
  • 22
    • 0034045748 scopus 로고    scopus 로고
    • Human CD4+ T lymphocytes with remarkable regulatory functions on dendritic cells and nickel-specific Th1 immune responses
    • Cavani A, Nasorri F, Prezzi C, Sebastiani S, Albanesi C, Girolomoni G (2000) Human CD4+ T lymphocytes with remarkable regulatory functions on dendritic cells and nickel-specific Th1 immune responses. J Invest Dermatol 114:295-302
    • (2000) J Invest Dermatol , vol.114 , pp. 295-302
    • Cavani, A.1    Nasorri, F.2    Prezzi, C.3    Sebastiani, S.4    Albanesi, C.5    Girolomoni, G.6
  • 23
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • Chen Y, Kuchroo VK, Inobe J, Hafler DA, Weiner HL (1994) Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265:1237-1240
    • (1994) Science , vol.265 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3    Hafler, D.A.4    Weiner, H.L.5
  • 26
    • 0036883901 scopus 로고    scopus 로고
    • Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora
    • Cong Y, Weaver CT, Lazenby A, Elson CO (2002) Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora. J Immunol 169:6112-6119
    • (2002) J Immunol , vol.169 , pp. 6112-6119
    • Cong, Y.1    Weaver, C.T.2    Lazenby, A.3    Elson, C.O.4
  • 27
    • 11144354531 scopus 로고    scopus 로고
    • Th2 cells are less susceptible than Th1 cells to the suppressive activity of CD25+ regulatory thymocytes because of their responsiveness to different cytokines
    • Cosmi L, Liotta F, Angeli R, Mazzinghi B, Santarlasci V, Manetti R, Lasagni L, Vanini V, Romagnani P, Maggi E et al (2004) Th2 cells are less susceptible than Th1 cells to the suppressive activity of CD25+ regulatory thymocytes because of their responsiveness to different cytokines. Blood 103:3117-3121
    • (2004) Blood , vol.103 , pp. 3117-3121
    • Cosmi, L.1    Liotta, F.2    Angeli, R.3    Mazzinghi, B.4    Santarlasci, V.5    Manetti, R.6    Lasagni, L.7    Vanini, V.8    Romagnani, P.9    Maggi, E.10
  • 29
    • 2442618129 scopus 로고    scopus 로고
    • CD4(+)CD25(bright) regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis
    • De Kleer IM, Wedderburn LR, Taams LS, Patel A, Varsani H, Klein M, De Jager W, Pugayung G, Giannoni F, Rijkers G et al (2004) CD4(+)CD25(bright) regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis. J Immunol 172:6435-6443
    • (2004) J Immunol , vol.172 , pp. 6435-6443
    • De Kleer, I.M.1    Wedderburn, L.R.2    Taams, L.S.3    Patel, A.4    Varsani, H.5    Klein, M.6    De Jager, W.7    Pugayung, G.8    Giannoni, F.9    Rijkers, G.10
  • 30
    • 0037099733 scopus 로고    scopus 로고
    • Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells
    • Dieckmann D, Bruett CH, Ploettner H, Lutz MB, Schuler G (2002) Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells. J Exp Med 196:247-253
    • (2002) J Exp Med , vol.196 , pp. 247-253
    • Dieckmann, D.1    Bruett, C.H.2    Ploettner, H.3    Lutz, M.B.4    Schuler, G.5
  • 31
    • 0035806244 scopus 로고    scopus 로고
    • Ex vivo isolation and characterization of CD4+CD25+ T cells with regulatory properties from human blood
    • Dieckmann D, Plottner H, Berchtold S, Berger T, Schuler S (2001) Ex vivo isolation and characterization of CD4+CD25+ T cells with regulatory properties from human blood. J Exp Med 193:1303-1310
    • (2001) J Exp Med , vol.193 , pp. 1303-1310
    • Dieckmann, D.1    Plottner, H.2    Berchtold, S.3    Berger, T.4    Schuler, S.5
  • 32
    • 2142645808 scopus 로고    scopus 로고
    • Cutting edge: TGF-beta Induces a regulatory phenotype in CD4(+)CD25(-) T cells through Foxp3 induction and down-regulation of Smad7
    • Fantini MC, Becker C, Monteleone G, Pallone F, Galle PR, Neurath MF (2004) Cutting edge: TGF-beta Induces a regulatory phenotype in CD4(+)CD25(-) T cells through Foxp3 induction and down-regulation of Smad7. J Immunol 172:5149-5153
    • (2004) J Immunol , vol.172 , pp. 5149-5153
    • Fantini, M.C.1    Becker, C.2    Monteleone, G.3    Pallone, F.4    Galle, P.R.5    Neurath, M.F.6
  • 34
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY (2003) Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 4:330-336
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 35
    • 0242412365 scopus 로고    scopus 로고
    • A comparative study between T regulatory type 1 and CD4+CD25+ T cells in the control of inflammation
    • Foussat A, Cottrez F, Brun V, Fournier N, Breittmayer JP, Groux H (2003) A comparative study between T regulatory type 1 and CD4+CD25+ T cells in the control of inflammation. J Immunol 171:5018-5026
    • (2003) J Immunol , vol.171 , pp. 5018-5026
    • Foussat, A.1    Cottrez, F.2    Brun, V.3    Fournier, N.4    Breittmayer, J.P.5    Groux, H.6
  • 36
    • 0037504093 scopus 로고    scopus 로고
    • Induction of IL-10+CD4+CD25+ T cells by grass pollen immunotherapy
    • Francis JN, Till SJ, Durham SR (2003) Induction of IL-10+CD4+CD25+ T cells by grass pollen immunotherapy. J Allergy Clin Immunol 111:1255-1261
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 1255-1261
    • Francis, J.N.1    Till, S.J.2    Durham, S.R.3
  • 38
    • 3142519564 scopus 로고    scopus 로고
    • In vitro-expanded human CD4(+)CD25(+)T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures
    • Godfrey WR, Ge YG, Spoden DJ, Levine BL, June CH, Blazar BR, Porter SB (2004) In vitro-expanded human CD4(+)CD25(+)T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures. Blood 104:453-461
    • (2004) Blood , vol.104 , pp. 453-461
    • Godfrey, W.R.1    Ge, Y.G.2    Spoden, D.J.3    Levine, B.L.4    June, C.H.5    Blazar, B.R.6    Porter, S.B.7
  • 39
    • 0038631849 scopus 로고    scopus 로고
    • Type 1 T-regulatory cells: Their role in the control of immune responses
    • Groux H (2003) Type 1 T-regulatory cells: their role in the control of immune responses. Transplantation 75:8S-12S
    • (2003) Transplantation , vol.75
    • Groux, H.1
  • 40
    • 0030058433 scopus 로고    scopus 로고
    • Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells
    • Groux H, Bigler M, de Vries JE, Roncarolo MG (1996) Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells. J Exp Med 184:19-29
    • (1996) J Exp Med , vol.184 , pp. 19-29
    • Groux, H.1    Bigler, M.2    De Vries, J.E.3    Roncarolo, M.G.4
  • 41
    • 0038617545 scopus 로고    scopus 로고
    • The complex role of interleukin-10 in autoimmunity
    • Groux H, Cottrez F (2003) The complex role of interleukin-10 in autoimmunity. J Autoimmun 20:281-285
    • (2003) J Autoimmun , vol.20 , pp. 281-285
    • Groux, H.1    Cottrez, F.2
  • 43
    • 0037114635 scopus 로고    scopus 로고
    • Interleukin-10-mediated regulatory T-cell responses to epitopes on a human red blood cell autoantigen
    • Hall AM, Ward FJ, Vickers MA, Stott LM, Urbaniak SJ, Barker RN (2002) Interleukin-10-mediated regulatory T-cell responses to epitopes on a human red blood cell autoantigen. Blood 100:4529-4536
    • (2002) Blood , vol.100 , pp. 4529-4536
    • Hall, A.M.1    Ward, F.J.2    Vickers, M.A.3    Stott, L.M.4    Urbaniak, S.J.5    Barker, R.N.6
  • 44
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S (2003) Control of regulatory T cell development by the transcription factor Foxp3. Science 299:1057-1061
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 45
    • 0141891466 scopus 로고    scopus 로고
    • Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers
    • Ichihara F, Kono K, Takahashi A, Kawaida H, Sugai H, Fujii H (2003) Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers. Clin Cancer Res 9:4404-4408
    • (2003) Clin Cancer Res , vol.9 , pp. 4404-4408
    • Ichihara, F.1    Kono, K.2    Takahashi, A.3    Kawaida, H.4    Sugai, H.5    Fujii, H.6
  • 46
    • 0035903307 scopus 로고    scopus 로고
    • Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells
    • Iellem A, Mariani M, Lang R, Recalde H, Panina-Bordignon P, Sinigaglia F, D'Ambrosio D (2001) Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells. J Exp Med 194:847-853
    • (2001) J Exp Med , vol.194 , pp. 847-853
    • Iellem, A.1    Mariani, M.2    Lang, R.3    Recalde, H.4    Panina-Bordignon, P.5    Sinigaglia, F.6    D'Ambrosio, D.7
  • 47
    • 0037099719 scopus 로고    scopus 로고
    • Infectious tolerance: Human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells
    • Jonuleit H, Schmitt E, Kakirman H, Stassen M, Knop J, Enk AH (2002) Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells. J Exp Med 196:255-260
    • (2002) J Exp Med , vol.196 , pp. 255-260
    • Jonuleit, H.1    Schmitt, E.2    Kakirman, H.3    Stassen, M.4    Knop, J.5    Enk, A.H.6
  • 48
    • 0034613767 scopus 로고    scopus 로고
    • Induction of interleukin-10-producing, nonproliferating CD4+ T cells with regulatory properties by repetitive stimulation with allogenic immature human dendritic cells
    • Jonuleit H, Schmitt E, Schuler G, Knop J, Enk AH (2000) Induction of interleukin-10-producing, nonproliferating CD4+ T cells with regulatory properties by repetitive stimulation with allogenic immature human dendritic cells. J Exp Med 192:1213-1222
    • (2000) J Exp Med , vol.192 , pp. 1213-1222
    • Jonuleit, H.1    Schmitt, E.2    Schuler, G.3    Knop, J.4    Enk, A.H.5
  • 49
    • 0035806290 scopus 로고    scopus 로고
    • Identification and functional characterization of human CD4+CD25+ T cells with regulatory properties isolated from peripheral blood
    • Jonuleit H, Schmitt E, Stassen M, Tuettenberg A, Knop J, Enk AH (2001) Identification and functional characterization of human CD4+CD25+ T cells with regulatory properties isolated from peripheral blood. J Exp Med 193:1285-1294
    • (2001) J Exp Med , vol.193 , pp. 1285-1294
    • Jonuleit, H.1    Schmitt, E.2    Stassen, M.3    Tuettenberg, A.4    Knop, J.5    Enk, A.H.6
  • 50
    • 0038363534 scopus 로고    scopus 로고
    • IL-10 and TGF-beta cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy
    • Jutel M, Akdis M, Budak F, Aebischer-Casaulta C, Wrzyszcz M, Blaser K, Akdis CA (2003) IL-10 and TGF-beta cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy. Eur J Immunol 33:1205-1214
    • (2003) Eur J Immunol , vol.33 , pp. 1205-1214
    • Jutel, M.1    Akdis, M.2    Budak, F.3    Aebischer-Casaulta, C.4    Wrzyszcz, M.5    Blaser, K.6    Akdis, C.A.7
  • 51
    • 2442494076 scopus 로고    scopus 로고
    • Human CD4(+)CD25(+) regulatory T cells share equally complex and comparable repertoires with CD4(+)CD25(-) counterparts
    • Kasow KA, Chen X, Knowles J, Wichlan D, Handgretinger R, Riberdy JM (2004) Human CD4(+)CD25(+) regulatory T cells share equally complex and comparable repertoires with CD4(+)CD25(-) counterparts. J Immunol 172:6123-6128
    • (2004) J Immunol , vol.172 , pp. 6123-6128
    • Kasow, K.A.1    Chen, X.2    Knowles, J.3    Wichlan, D.4    Handgretinger, R.5    Riberdy, J.M.6
  • 52
    • 0347895101 scopus 로고    scopus 로고
    • Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype
    • Kemper C, Chan AC, Green JM, Brett KA, Murphy KM, Atkinson JP (2003) Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype. Nature 421:388-392
    • (2003) Nature , vol.421 , pp. 388-392
    • Kemper, C.1    Chan, A.C.2    Green, J.M.3    Brett, K.A.4    Murphy, K.M.5    Atkinson, J.P.6
  • 53
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4+CD25+ T regulatory cells
    • Khattri R, Cox T, Yasayko SA, Ramsdell F (2003) An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol 4:337-342
    • (2003) Nat Immunol , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 54
    • 0034661662 scopus 로고    scopus 로고
    • Activated self-MHC-reactive T cells have the cytokine phenotype of Th3/T regulatory cell 1 T cells
    • Kitani A, Chua K, Nakamura K, Strober W (2000) Activated self-MHC-reactive T cells have the cytokine phenotype of Th3/T regulatory cell 1 T cells. J Immunol 165:691-702
    • (2000) J Immunol , vol.165 , pp. 691-702
    • Kitani, A.1    Chua, K.2    Nakamura, K.3    Strober, W.4
  • 55
    • 0346366991 scopus 로고    scopus 로고
    • IL-15 and cognate antigen successfully expand de novo-induced human antigen-specific regulatory CD4+ T cells that require antigen-specific activation for suppression
    • Koenen HJ, Fasse E, Joosten I (2003) IL-15 and cognate antigen successfully expand de novo-induced human antigen-specific regulatory CD4+ T cells that require antigen-specific activation for suppression. J Immunol 171:6431-6441
    • (2003) J Immunol , vol.171 , pp. 6431-6441
    • Koenen, H.J.1    Fasse, E.2    Joosten, I.3
  • 56
    • 2442628376 scopus 로고    scopus 로고
    • Defective Suppressor Function of Human CD4+ CD25+ Regulatory T Cells in Autoimmune Polyglandular Syndrome Type II
    • Kriegel MA, Lohmann T, Gabler C, Blank N, Kalden JR., Lorenz HM (2004) Defective Suppressor Function of Human CD4+ CD25+ Regulatory T Cells in Autoimmune Polyglandular Syndrome Type II. J Exp Med 199:1285-1291
    • (2004) J Exp Med , vol.199 , pp. 1285-1291
    • Kriegel, M.A.1    Lohmann, T.2    Gabler, C.3    Blank, N.4    Kalden, J.R.5    Lorenz, H.M.6
  • 59
    • 0035720180 scopus 로고    scopus 로고
    • Phenotypic characterization of human CD4+ regulatory T cells obtained from cutaneous dinitrochlorobenzene-induced delayed type hypersensitivity reactions
    • Lecart S, Boulay V, Raison-Peyron N, Bousquet J, Meunier L, Yssel H, Pene J (2001) Phenotypic characterization of human CD4+ regulatory T cells obtained from cutaneous dinitrochlorobenzene-induced delayed type hypersensitivity reactions. J Invest Dermatol 117:318-325
    • (2001) J Invest Dermatol , vol.117 , pp. 318-325
    • Lecart, S.1    Boulay, V.2    Raison-Peyron, N.3    Bousquet, J.4    Meunier, L.5    Yssel, H.6    Pene, J.7
  • 60
    • 0036886390 scopus 로고    scopus 로고
    • The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells
    • Levings MK, Bacchetta R, Schulz U, Roncarolo MG (2002) The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells. Int Arch Allergy Immunol 129:263-276
    • (2002) Int Arch Allergy Immunol , vol.129 , pp. 263-276
    • Levings, M.K.1    Bacchetta, R.2    Schulz, U.3    Roncarolo, M.G.4
  • 61
    • 12844274909 scopus 로고    scopus 로고
    • Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Treg cells
    • e-pub Oct 12 DOI 15479730
    • Levings MK, Gregori S, Tresoldi E, Cazzaniga S, Bonini C, Roncarolo MG (2004) Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Treg cells. Blood 105:1162-1169; e-pub Oct 12 DOI 15479730
    • (2004) Blood , vol.105 , pp. 1162-1169
    • Levings, M.K.1    Gregori, S.2    Tresoldi, E.3    Cazzaniga, S.4    Bonini, C.5    Roncarolo, M.G.6
  • 63
    • 0035806323 scopus 로고    scopus 로고
    • Human CD25+CD4+ T regulatory cells suppress naive and memory T-cell proliferation and can be expanded in vitro without loss of function
    • Levings MK, Sangregorio R, Roncarolo MG (2001) Human CD25+CD4+ T regulatory cells suppress naive and memory T-cell proliferation and can be expanded in vitro without loss of function. J Exp Med 193:1295-1302
    • (2001) J Exp Med , vol.193 , pp. 1295-1302
    • Levings, M.K.1    Sangregorio, R.2    Roncarolo, M.G.3
  • 64
    • 0037131969 scopus 로고    scopus 로고
    • Human CD25+CD4+ T suppressor cell clones produce TGF-β, but not IL-10 and are distinct from type 1 T regulatory cells
    • Levings MK, Sangregorio R, Sartirana C, Moschin AL, Battaglia M, Orban PC, Roncarolo MG (2002) Human CD25+CD4+ T suppressor cell clones produce TGF-β, but not IL-10 and are distinct from type 1 T regulatory cells. J Exp Med 196:1335-1346
    • (2002) J Exp Med , vol.196 , pp. 1335-1346
    • Levings, M.K.1    Sangregorio, R.2    Sartirana, C.3    Moschin, A.L.4    Battaglia, M.5    Orban, P.C.6    Roncarolo, M.G.7
  • 65
    • 1342267617 scopus 로고    scopus 로고
    • Decreased CD4+CD25+ T cells in peripheral blood of patients with systemic lupus erythematosus
    • Liu MF, Wang CR, Fung LL, Wu CR (2004) Decreased CD4+CD25+ T cells in peripheral blood of patients with systemic lupus erythematosus. Scand J Immunol 59:198-202
    • (2004) Scand J Immunol , vol.59 , pp. 198-202
    • Liu, M.F.1    Wang, C.R.2    Fung, L.L.3    Wu, C.R.4
  • 66
    • 0037086525 scopus 로고    scopus 로고
    • CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons
    • MacDonald AJ, Duffy M, Brady MT, McKiernan S, Hall W, Hegarty J, Curry M, Mills KH (2002) CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons. J Infect Dis 185:720-727
    • (2002) J Infect Dis , vol.185 , pp. 720-727
    • MacDonald, A.J.1    Duffy, M.2    Brady, M.T.3    McKiernan, S.4    Hall, W.5    Hegarty, J.6    Curry, M.7    Mills, K.H.8
  • 67
    • 0037243827 scopus 로고    scopus 로고
    • CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms
    • Maloy KJ, Salaun L, Cahill R, Dougan G, Saunders NJ, Powrie F (2003) CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J Exp Med 197:111-119
    • (2003) J Exp Med , vol.197 , pp. 111-119
    • Maloy, K.J.1    Salaun, L.2    Cahill, R.3    Dougan, G.4    Saunders, N.J.5    Powrie, F.6
  • 69
    • 0038280092 scopus 로고    scopus 로고
    • Regulatory T cells secreting IL-10 dominate the immune response to EBV latent membrane protein 1
    • Marshall NA, Vickers MA, Barker RN (2003) Regulatory T cells secreting IL-10 dominate the immune response to EBV latent membrane protein 1. J Immunol 170:6183-6189
    • (2003) J Immunol , vol.170 , pp. 6183-6189
    • Marshall, N.A.1    Vickers, M.A.2    Barker, R.N.3
  • 70
    • 0037240852 scopus 로고    scopus 로고
    • Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10
    • Martin E, O'Sullivan B, Low P, Thomas R (2003) Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10. Immunity 18:155-167
    • (2003) Immunity , vol.18 , pp. 155-167
    • Martin, E.1    O'Sullivan, B.2    Low, P.3    Thomas, R.4
  • 71
    • 0037148511 scopus 로고    scopus 로고
    • Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: A novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis
    • McGuirk P, McCann C, Mills KH (2002) Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis. J Exp Med 195:221-231
    • (2002) J Exp Med , vol.195 , pp. 221-231
    • McGuirk, P.1    McCann, C.2    Mills, K.H.3
  • 72
    • 1842581857 scopus 로고    scopus 로고
    • Cutting edge: Human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells
    • Misra N, Bayry J, Lacroix-Desmazes S, Kazatchkine MD, Kaveri SV (2004) Cutting edge: human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells. J Immunol 172:4676-4680
    • (2004) J Immunol , vol.172 , pp. 4676-4680
    • Misra, N.1    Bayry, J.2    Lacroix-Desmazes, S.3    Kazatchkine, M.D.4    Kaveri, S.V.5
  • 73
    • 1642577126 scopus 로고    scopus 로고
    • TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice
    • Nakamura K, Kitani A, Fuss I, Pedersen A, Harada N, Nawata H, Strober W (2004) TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice. J Immunol 172:834-842
    • (2004) J Immunol , vol.172 , pp. 834-842
    • Nakamura, K.1    Kitani, A.2    Fuss, I.3    Pedersen, A.4    Harada, N.5    Nawata, H.6    Strober, W.7
  • 74
    • 0035801335 scopus 로고    scopus 로고
    • Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
    • Nakamura K, Kitani A, Strober W (2001) Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J Exp Med 194:629-644
    • (2001) J Exp Med , vol.194 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 76
    • 0037436119 scopus 로고    scopus 로고
    • Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
    • Pasare C, Medzhitov R (2003) Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science 299:1033-1036
    • (2003) Science , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 77
    • 0034161714 scopus 로고    scopus 로고
    • 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, survival of dendritic cells leading to impaired alloreactive T cell activation
    • Penna G, Adorini L (2000) 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, survival of dendritic cells leading to impaired alloreactive T cell activation. J Immunol 164:2405-2411
    • (2000) J Immunol , vol.164 , pp. 2405-2411
    • Penna, G.1    Adorini, L.2
  • 78
    • 0037099613 scopus 로고    scopus 로고
    • CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness
    • Piccirillo CA, Letterio JJ, Thornton AM, McHugh RS, Mamura M, Mizuhara H, Shevach EM (2002) CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness. J Exp Med 196:237-246
    • (2002) J Exp Med , vol.196 , pp. 237-246
    • Piccirillo, C.A.1    Letterio, J.J.2    Thornton, A.M.3    McHugh, R.S.4    Mamura, M.5    Mizuhara, H.6    Shevach, E.M.7
  • 79
    • 1242295282 scopus 로고    scopus 로고
    • Naturally-occurring CD4+CD25+ immunoregulatory T cells: Central players in the arena of peripheral tolerance
    • Piccirillo CA, Shevach EM (2004) Naturally-occurring CD4+CD25+ immunoregulatory T cells: central players in the arena of peripheral tolerance. Semin Immunol 16:81-88
    • (2004) Semin Immunol , vol.16 , pp. 81-88
    • Piccirillo, C.A.1    Shevach, E.M.2
  • 80
    • 1842607712 scopus 로고    scopus 로고
    • Circulating CD4(+)CD25(+) T regulatory cells are not altered in multiple sclerosis and unaffected by disease-modulating drugs
    • Putheti P, Pettersson A, Soderstrom M, Link H, Huang YM (2004) Circulating CD4(+)CD25(+) T regulatory cells are not altered in multiple sclerosis and unaffected by disease-modulating drugs. J Clin Immunol 24:155-161
    • (2004) J Clin Immunol , vol.24 , pp. 155-161
    • Putheti, P.1    Pettersson, A.2    Soderstrom, M.3    Link, H.4    Huang, Y.M.5
  • 81
    • 1342282321 scopus 로고    scopus 로고
    • A role for IL-10-mediated HLA-DR7-restricted T cell-dependent events in development of the modified Th2 response to cat allergen
    • Reefer AJ, Carneiro RM, Custis NJ, Platts-Mills TA, Sung SS, Hammer J, Woodfolk JA (2004) A role for IL-10-mediated HLA-DR7-restricted T cell-dependent events in development of the modified Th2 response to cat allergen. J Immunol 172:2763-2772
    • (2004) J Immunol , vol.172 , pp. 2763-2772
    • Reefer, A.J.1    Carneiro, R.M.2    Custis, N.J.3    Platts-Mills, T.A.4    Sung, S.S.5    Hammer, J.6    Woodfolk, J.A.7
  • 83
    • 0033738329 scopus 로고    scopus 로고
    • The role of different subsets of T regulatory cells in controlling autoimmunity
    • Roncarolo MG, Levings MK (2000) The role of different subsets of T regulatory cells in controlling autoimmunity. Curr Opin Immunol 12:676-683
    • (2000) Curr Opin Immunol , vol.12 , pp. 676-683
    • Roncarolo, M.G.1    Levings, M.K.2
  • 85
    • 0034716925 scopus 로고    scopus 로고
    • Regulatory T cells: Key controllers of immunologic self-tolerance
    • Sakaguchi S (2000) Regulatory T cells: key controllers of immunologic self-tolerance. Cell 101:455-458
    • (2000) Cell , vol.101 , pp. 455-458
    • Sakaguchi, S.1
  • 86
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi S (2004) Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 22:531-562
    • (2004) Annu Rev Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 87
    • 0041386189 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells in patients with gastrointestinal malignancies: Possible involvement of regulatory T cells in disease progression
    • Sasada T, Kimura M, Yoshida Y, Kanai M, Takabayashi A (2003) CD4+CD25+ regulatory T cells in patients with gastrointestinal malignancies: possible involvement of regulatory T cells in disease progression. Cancer 98:1089-1099
    • (2003) Cancer , vol.98 , pp. 1089-1099
    • Sasada, T.1    Kimura, M.2    Yoshida, Y.3    Kanai, M.4    Takabayashi, A.5
  • 90
    • 0034084162 scopus 로고    scopus 로고
    • Regulatory T cells in autoimmmunity
    • Shevach EM (2000) Regulatory T cells in autoimmmunity. Annu Rev Immunol 18:423-449
    • (2000) Annu Rev Immunol , vol.18 , pp. 423-449
    • Shevach, E.M.1
  • 91
    • 9144261074 scopus 로고    scopus 로고
    • CD25 expression on donor CD4+ or CD8+ T cells is associated with an increased risk for graft-versus-host disease after HLA-identical stem cell transplantation in humans
    • Stanzani M, Martins SL, Saliba RM, St John LS, Bryan S, Couriel D, McMannis J, Champlin RE, Molldrem JJ, Komanduri KV (2004) CD25 expression on donor CD4+ or CD8+ T cells is associated with an increased risk for graft-versus-host disease after HLA-identical stem cell transplantation in humans. Blood 103:1140-1146
    • (2004) Blood , vol.103 , pp. 1140-1146
    • Stanzani, M.1    Martins, S.L.2    Saliba, R.M.3    St. John, L.S.4    Bryan, S.5    Couriel, D.6    McMannis, J.7    Champlin, R.E.8    Molldrem, J.J.9    Komanduri, K.V.10
  • 92
    • 2942733256 scopus 로고    scopus 로고
    • Human CD25+ regulatory T cells: Two subsets defined by the integrins alpha4beta7 or alpha4beta1 confer distinct suppressive properties upon CD4+ T helper cells
    • Stassen M, Fondel S, Bopp T, Richter C, Müller C, Kubach J, Becker C, Knop J, Enk AH, Schmitt S et al (2004) Human CD25+ regulatory T cells: two subsets defined by the integrins alpha4beta7 or alpha4beta1 confer distinct suppressive properties upon CD4+ T helper cells. Eur J Immunol 34:1303-1311
    • (2004) Eur J Immunol , vol.34 , pp. 1303-1311
    • Stassen, M.1    Fondel, S.2    Bopp, T.3    Richter, C.4    Müller, C.5    Kubach, J.6    Becker, C.7    Knop, J.8    Enk, A.H.9    Schmitt, S.10
  • 93
    • 1642575975 scopus 로고    scopus 로고
    • Human CD(4+)CD(25+) regulatory T cells and infectious tolerance
    • Stassen M, Schmitt E, Jonuleit H (2004) Human CD(4+)CD(25+) regulatory T cells and infectious tolerance. Transplantation 77:S23-S25
    • (2004) Transplantation , vol.77
    • Stassen, M.1    Schmitt, E.2    Jonuleit, H.3
  • 94
    • 0036733569 scopus 로고    scopus 로고
    • CD4(+) CD25(+) T-cell production in healthy humans and in patients with thymic hypoplasia
    • Sullivan KE, McDonald-McGinn D, Zackai EH (2002) CD4(+) CD25(+) T-cell production in healthy humans and in patients with thymic hypoplasia. Clin Diagn Lab Immunol 9:1129-1131
    • (2002) Clin Diagn Lab Immunol , vol.9 , pp. 1129-1131
    • Sullivan, K.E.1    McDonald-McGinn, D.2    Zackai, E.H.3
  • 95
    • 0035062581 scopus 로고    scopus 로고
    • Human anergic/suppressive CD4(+)CD25(+) T cells: A highly differentiated and apoptosis-prone population
    • Taams LS, Smith J, Rustin MH, Salmon M, Poulter LW, Akbar AN (2001) Human anergic/suppressive CD4(+)CD25(+) T cells: a highly differentiated and apoptosis-prone population. Eur J Immunol 31:1122-1131
    • (2001) Eur J Immunol , vol.31 , pp. 1122-1131
    • Taams, L.S.1    Smith, J.2    Rustin, M.H.3    Salmon, M.4    Poulter, L.W.5    Akbar, A.N.6
  • 97
    • 0037093217 scopus 로고    scopus 로고
    • The infusion of ex vivo activated and expanded CD4+CD25+ immune regulatory cells inhibits graft-versus-host disease lethality
    • Taylor P, Lees CJ, Blazar BR (2002) The infusion of ex vivo activated and expanded CD4+CD25+ immune regulatory cells inhibits graft-versus-host disease lethality. Blood 99:3493-3499
    • (2002) Blood , vol.99 , pp. 3493-3499
    • Taylor, P.1    Lees, C.J.2    Blazar, B.R.3
  • 98
    • 1642390941 scopus 로고    scopus 로고
    • Activation requirements for the induction of CD4+CD25+ T cell suppressor function
    • Thornton AM, Piccirillo CA, Shevach EM (2004) Activation requirements for the induction of CD4+CD25+ T cell suppressor function. Eur J Immunol 34:366-376
    • (2004) Eur J Immunol , vol.34 , pp. 366-376
    • Thornton, A.M.1    Piccirillo, C.A.2    Shevach, E.M.3
  • 100
    • 2442535915 scopus 로고    scopus 로고
    • Type I regulatory T cells specific for desmoglein 3 are more frequently detected in healthy individuals than in patients with pemphigus vulgaris
    • Veldman C, Hohne A, Dieckmann D, Schuler G, Hertl M (2004) Type I regulatory T cells specific for desmoglein 3 are more frequently detected in healthy individuals than in patients with pemphigus vulgaris. J Immunol 172:6468-6475
    • (2004) J Immunol , vol.172 , pp. 6468-6475
    • Veldman, C.1    Hohne, A.2    Dieckmann, D.3    Schuler, G.4    Hertl, M.5
  • 101
    • 2142825777 scopus 로고    scopus 로고
    • Human T cell activation by costimulatory signal-deficient allogeneic cells induces inducible costimulator-expressing anergic T cells with regulatory cell activity
    • Vermeiren J, Ceuppens JL, Van Ghelue M, Witters P, Bullens D, Mages HW, Kroczek RA, Van Gool SW (2004) Human T cell activation by costimulatory signal-deficient allogeneic cells induces inducible costimulator-expressing anergic T cells with regulatory cell activity. J Immunol 172:5371-5378
    • (2004) J Immunol , vol.172 , pp. 5371-5378
    • Vermeiren, J.1    Ceuppens, J.L.2    Van Ghelue, M.3    Witters, P.4    Bullens, D.5    Mages, H.W.6    Kroczek, R.A.7    Van Gool, S.W.8
  • 103
    • 1842732224 scopus 로고    scopus 로고
    • Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
    • Viglietta V, Baecher-Allan C, Weiner HL, Hafler DA (2004) Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J Exp Med 199:971-979
    • (2004) J Exp Med , vol.199 , pp. 971-979
    • Viglietta, V.1    Baecher-Allan, C.2    Weiner, H.L.3    Hafler, D.A.4
  • 104
    • 3142737258 scopus 로고    scopus 로고
    • Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells
    • Viguier M, Lemaitre F, Verola O, Cho MS, Gorochov G, Dubertret L, Bachelez H, Kourilsky P, Ferradini L (2004) Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells. J Immunol 173:1444-1453
    • (2004) J Immunol , vol.173 , pp. 1444-1453
    • Viguier, M.1    Lemaitre, F.2    Verola, O.3    Cho, M.S.4    Gorochov, G.5    Dubertret, L.6    Bachelez, H.7    Kourilsky, P.8    Ferradini, L.9
  • 105
    • 0035885068 scopus 로고    scopus 로고
    • Differentiation of regulatory T cells 1 is induced by CD2 costimulation
    • Wakkach A, Cottrez F, Groux H (2001) Differentiation of regulatory T cells 1 is induced by CD2 costimulation. J Immunol 167:3107-3113
    • (2001) J Immunol , vol.167 , pp. 3107-3113
    • Wakkach, A.1    Cottrez, F.2    Groux, H.3
  • 106
    • 0037987977 scopus 로고    scopus 로고
    • Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo
    • Wakkach A, Fournier N, Brun V, Breittmayer JP, Cottrez F, Groux H (2003) Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity 18:605-617
    • (2003) Immunity , vol.18 , pp. 605-617
    • Wakkach, A.1    Fournier, N.2    Brun, V.3    Breittmayer, J.P.4    Cottrez, F.5    Groux, H.6
  • 109
    • 1642497640 scopus 로고    scopus 로고
    • Tumor-specific human CD4+ regulatory T cells and their ligands: Implications for immunotherapy
    • Wang HY, Lee DA, Peng G, Guo Z, Li Y, Kiniwa Y, Shevach EM, Wang RF (2004) Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy. Immunity 20:107-118
    • (2004) Immunity , vol.20 , pp. 107-118
    • Wang, H.Y.1    Lee, D.A.2    Peng, G.3    Guo, Z.4    Li, Y.5    Kiniwa, Y.6    Shevach, E.M.7    Wang, R.F.8
  • 110
    • 0036346861 scopus 로고    scopus 로고
    • Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome
    • Wildin RS, Smyk-Pearson S, Filipovich AH (2002) Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome. J Med Genet 39:537-545
    • (2002) J Med Genet , vol.39 , pp. 537-545
    • Wildin, R.S.1    Smyk-Pearson, S.2    Filipovich, A.H.3
  • 111
    • 0036284229 scopus 로고    scopus 로고
    • Characterization of human CD25+ CD4+ T cells in thymus, cord and adult blood
    • Wing K, Ekmark A, Karlsson H, Rudin A, Suri-Payer E (2002) Characterization of human CD25+ CD4+ T cells in thymus, cord and adult blood. Immunology 106:190-199
    • (2002) Immunology , vol.106 , pp. 190-199
    • Wing, K.1    Ekmark, A.2    Karlsson, H.3    Rudin, A.4    Suri-Payer, E.5
  • 112
    • 0035876913 scopus 로고    scopus 로고
    • A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood
    • Yamagiwa S, Gray JD, Hashimoto S, Horwitz DA (2001) A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood. J Immunol 166:7282-7289
    • (2001) J Immunol , vol.166 , pp. 7282-7289
    • Yamagiwa, S.1    Gray, J.D.2    Hashimoto, S.3    Horwitz, D.A.4
  • 113
    • 0034743546 scopus 로고    scopus 로고
    • Role of NFkappaB in antigen presentation and development of regulatory T cells elucidated by treatment of dendritic cells with the proteasome inhibitor PSI
    • Yoshimura S, Bondeson J, Brennan FM, Foxwell BM, Feldmann M (2001) Role of NFkappaB in antigen presentation and development of regulatory T cells elucidated by treatment of dendritic cells with the proteasome inhibitor PSI. Eur J Immunol 31:1883-1893
    • (2001) Eur J Immunol , vol.31 , pp. 1883-1893
    • Yoshimura, S.1    Bondeson, J.2    Brennan, F.M.3    Foxwell, B.M.4    Feldmann, M.5
  • 115
    • 1242290580 scopus 로고    scopus 로고
    • Natural and induced CD4(+)CD25(+) cells educate CD4(+)CD25(-) cells to develop suppressive activity: The role of IL-2, TGF-beta, IL-10
    • Zheng SG, Wang JH, Gray JD, Soucier H, Horwitz DA (2004) Natural and induced CD4(+)CD25(+) cells educate CD4(+)CD25(-) cells to develop suppressive activity: the role of IL-2, TGF-beta, IL-10. J Immunol 172:5213-5221
    • (2004) J Immunol , vol.172 , pp. 5213-5221
    • Zheng, S.G.1    Wang, J.H.2    Gray, J.D.3    Soucier, H.4    Horwitz, D.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.