Ascorbate depletion: A critical step in nickel carcinogenesis?

Environmental Health Perspectives

Volumn 113, Issue 5, 2005, Pages 577-584

  Salnikow, Konstantin ^a   Kasprzak, Kazimierz S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Ascorbate; Carcinogenesis; Collagens; Extracellular matrix; Hypoxia inducible transcription factor; Metals; Nickel; Protein hydroxylation

Indexed keywords

ASCORBIC ACID; COLLAGEN; COMPLEMENT; DNA; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; METAL COMPLEX; NICKEL; OXYGENASE; PROLINE; PROTEIN; SURFACTANT;

CARCINOGENESIS; CARCINOGENICITY; CELL SELECTION; CELL TRANSFORMATION; ENZYME INHIBITION; EXPERIMENTAL ANIMAL; EXTRACELLULAR MATRIX; GENOTOXICITY; HOMEOSTASIS; HUMAN; HYDROXYLATION; HYPOXIA; LONG TERM EXPOSURE; LUNG ALVEOLUS CELL; LUNG CANCER; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; RESPIRATORY TRACT CANCER; REVIEW; STRESS;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; CELL TRANSFORMATION, NEOPLASTIC; DNA DAMAGE; HOMEOSTASIS; HUMANS; HYDROXYLATION; LUNG NEOPLASMS; NICKEL; PROLINE; PROTEIN BINDING; RATS;

ANIMALIA;

EID: 19044392200     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.7605     Document Type: Review

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