Nickel subsulfide is genotoxic in vitro but shows no mutagenic potential in respiratory tract tissues of BigBlue(TM) rats and Muta(TM)Mouse mice in vivo after inhalation

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 420, Issue 1-3, 1998, Pages 85-98

  Mayer, Claudia ^a   Klein, Reinhold G ^a   Wesch, Horst ^a   Schmezer, Peter ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Comet assay; lacI; lacZ; Nickel compound; Transgenic rodent mutation assay

Indexed keywords

DNA FRAGMENT; NICKEL; NICKEL SUBSULFIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DNA DAMAGE; DNA METHYLATION; DNA SEQUENCE; DNA STRAND; GENE SILENCING; IN VITRO STUDY; LUNG PARENCHYMA; MOUSE; MUTAGENICITY; MUTATION; MUTATION RATE; NONHUMAN; NOSE MUCOSA; PRIORITY JOURNAL; RAT;

ADMINISTRATION, INHALATION; ANIMALS; CARCINOGENS; CELLS, CULTURED; DNA; DNA FRAGMENTATION; DNA PRIMERS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, AGAR GEL; LUNG; MALE; MICE; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MUTAGENESIS; NASAL MUCOSA; NICKEL; POLYMERASE CHAIN REACTION; RANDOM ALLOCATION; RATS; RATS, INBRED F344; RATS, MUTANT STRAINS; SEQUENCE ANALYSIS, DNA; SPECTROPHOTOMETRY, ATOMIC;

MAMMALIA; MUS MUSCULUS; RODENTIA;

EID: 0032406971     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(98)00140-5     Document Type: Article

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