Surfactant proteins A and D and pulmonary host defense

Annual Review of Physiology

Volumn 63, Issue , 2001, Pages 521-554

  Crouch, E ^a   Wright, J R ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alveolar; C type lectin; Collectin; Pulmonary surfactant

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CARBOHYDRATE; COLLECTIN; GLYCOCONJUGATE; LECTIN; LIPID; LUNG SURFACTANT; SURFACTANT PROTEIN A; SURFACTANT PROTEIN B;

HOST RESISTANCE; HUMAN; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; LEUKOCYTE FUNCTION; LUNG ALVEOLUS; LUNG INJURY; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE; RESPIRATORY TRACT INFECTION; RESPIRATORY TRACT INFLAMMATION; REVIEW;

ANIMALS; GLYCOPROTEINS; HUMANS; IMMUNOCOMPETENCE; LUNG; PNEUMONIA; PROTEOLIPIDS; PULMONARY SURFACTANT-ASSOCIATED PROTEIN A; PULMONARY SURFACTANT-ASSOCIATED PROTEIN D; PULMONARY SURFACTANT-ASSOCIATED PROTEINS; PULMONARY SURFACTANTS;

EID: 0035048532     PISSN: 00664278     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.physiol.63.1.521     Document Type: Review

References (193)

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8. Interaction of human lung surfactant proteins A and D with mite (Dermatophagoides pteronyssinus) allergens
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13. The major lung surfactant protein, SP 28-36, is a calcium-dependent, carbohydrate-binding protein
14. Surfactant protein D is a divalent cationdependent carbohydrate-binding protein
15. Expression of the carbohydrate recognition domain of lung surfactant protein D and demonstration of its binding to lipopolysaccharides of gram-negative bacteria
16. SP-A enhances phagocytosis of Klebsiella by interaction with capsular polysaccharides and alveolar macrophages
17. Surfactant protein D binds to Mycobacterium tuberculosis bacilli and lipoarabinomannan via carbohydrate-lectin interactions resulting in reduced phagocytosis of the bacteria by macrophages
18. The alpha-helical neck region of human lung surfactant protein D is essential for the binding of the carbohydrate recognition domains to lipopolysaccharides and phospholipids
19. Crystal structure of the trimeric alpha-helical coiled-coil and the three lectin domains of human lung surfactant protein D
20. Pulmonary surfactant protein A (SP-A) specifically binds dipalmitoylphosphatidylcholine
21. Binding of calcium to SP-A, a surfactant-associated protein
22. Binding of surfactant protein A to the lipid A moiety of bacterial lipopolysaccharides
23. Interaction of surfactant protein A with bacterial lipopolysaccharide may affect some biological functions
24. Developmental changes of neutral glycosphingolipids as receptors for pulmonary surfactant protein SP-A in the alveolar epithelium of murine lung
25. Binding of pulmonary surfactant protein A to galactosylceramide and asialo-GM2
26. Specificity of lung surfactant protein SP-A for both the carbohydrate and the lipid moieties of certain neutral glycolipids
27. The major glycolipid recognized by SP-D in surfactant is phosphatidylinositol
28. Pulmonary surfactant protein D specifically binds to phosphatidylinositol
29. Chimeras of surfactant proteins A and D identify the carbohydrate recognition domains as essential for phospholipid interaction
30. Binding specificity of lung surfactant protein SP-D for glucosylceramide
31. Importance of the carboxy-terminal 25 amino acid residues of lung collectins in interactions with lipids and alveolar type II cells
32. Analysis of chimeric proteins identifies the regions in the carbohydrate recognition domains of rat lung collectins that are essential for interactions with phospholipids, glycolipids, and alveolar type II cells
33. Bacterial polysaccharides
34. Chemical structure of the core region of lipopolysaccharide
35. Interactions of surfactant protein D with bacterial lipopolysaccharides. Surfactant protein D is an Escherichia coli-binding protein in bronchoalveolar lavage
36. Aggregation and opsonization of type A but not type B Hemophilus influenzae by surfactant protein A
37. Surfactant protein A promotes attachment of Mycobacterium tuberculosis to alveolar macrophages during infection with human immunodeficiency virus
38. Pulmonary surfactant protein A mediates enhanced phagocytosis of Mycobacterium tuberculosis by a direct interaction with human macrophages
39. Binding of host collectins to the pathogenic yeast Cryptococcus neoformans: Human surfactant protein D acts as an agglutinin for acapsular yeast cells
40. Lung surfactant proteins A and D can inhibit specific IgE binding to the allergens of Aspergillus fumigatus and block allergen-induced histamine release from human basophils
41. Binding of pulmonary surfactant proteins A and D to Aspergillus fumigatus conidia enhances phagocytosis and killing by human neutrophils and alveolar macrophages
42. Binding of rat and human surfactant proteins A and D to Aspergillus fumigatus conidia
43. Interactions of pulmonary surfactant proteins A and D with Saccharomyces cerevisiae
44. Human surfactant protein A enhances attachment of Pneumocystis carnii to rat alveolar macrophages
45. 120-kD surface glycoprotein of Pneumocystis carinii is a ligand for surfactant protein A
46. Surfactant protein D interacts with Pneumocystis carinii and mediates organism adherence to alveolar macrophages
47. The carbohydrate recognition domain of surfactant protein A mediates binding to the major surface glycoprotein of Pneumocystis carinii
48. Surfactant protein-D binds to cell wall beta-lucans
49. Surfactant protein-D mediates aggregation of Pseumocystis carnii
50. Recognition of Pneumocystis carinii antigen on its surface by immunohistochemistry and immunoelectron microscopy
51. Evidence for a protective role of pulmonary surfactant protein D (SP-D) against influenza A viruses
52. Interactions of surfactant protein A with influenza A viruses: Binding and neutralization
53. Mechanisms of anti-influenza activity of surfactant proteins A and D: Comparison with serum collectins
54. Collectin-mediated antiviral host defense of the lung: Evidence from influenza virus infection of mice
55. Interactions of recombinant human pulmonary surfactant protein D and SP-D multimers with influenza A
56. Neutrophil deactivation by influenza A viruses - Mechanisms of protection after viral opsonization with collectins and hemaglutination-inhibiting antibodies
57. Pulmonary surfactant proteins A and D enhance neutrophil uptake of bacteria
58. Surfactant protein A binds to the fusion glycoprotein of respiratory syncytial virus and neutralizes virion infectivity
59. A recombinant trimeric surfactant protein D carbohydrate recognition domain inhibits respiratory syncytial virus infection in vitro and in vivo
60. Antiviral activity of bovine collectins against rotaviruses
61. Surfactant protein A is opsonin in phagocytosis of herpes simplex virus type 1 by rat alveolar macrophages
62. Binding of surfactant protein A (SP-A) to herpes simplex virus type 1-infected cells is mediated by the carbohydrate moiety of SP-A
63. Interactions of microbial glycoconjugates with collectins: Implications for pulmonary host defense
64. Interactions of SP-A and SP-D with LPS
65. Consequences of reduction of Klebsiella pneumoniae capsule expression on interactions of this bacterium with epithelial cells
66. Lung surfactant protein A (SP-A) enhances serum-independent phagocytosis of bacteria by alveolar macrophages
67. Human lung surfactant protein A exists in several different oligomeric states - Oligomer size distribution varies between patient groups
68. A 50-kDa variant form of human surfactant protein D
69. Biosynthesis of surfactant protein D. Contributions of conserved NH2-terminal cysteine residues and collagen helix formation to assembly and secretion
70. Collectins and pulmonary innate immunity
71. Increased susceptibility of diabetic mice to influenza virus infection: Compromise of collectin-mediated host defense of the lung by glucose?
72. Aerosolized endotoxin is immediately bound by pulmonary surfactant protein D in vivo
73. Effects of activated polymorphonuclear leukocytes upon pulmonary surfactant in vitro
74. A metalloproteinase secreted by Pseudomonas aeruginosa degrades pulmonary surfactant protein A (SP-A)
75. Nitrated SP-A does not enhance adherence of Pneumocystis carinii to alveolar macrophages
76. Nitration of surfactant protein A tesults in decreased ability to aggregate lipids
77. Nitrated SP-A does not enhance adherence of Pneumocystis carinii to alveolar macrophages
78. Nitration of surfactant protein A (SP-A) tyrosine residues results in decreased mannose binding ability
79. Cytokine expression by neutrophils and macrophages in vivo: Endotoxin induces tumor necrosis factor-alpha, macrophage inflammatory protein-2, interleukin-1 beta, and interleukin-6 but not RANTES or transforming growth factor-beta 1 mRNA expression in acute lung inflammation
80. Human pulmonary surfactant protein (SP-A), a protein structurally homologous to C1q, can enhance FcR- and CR1-mediated phagocytosis
81. Surfactant protein-A inhibits binding and internalization of Pneumocystis carinii by alveolar macrophages
82. Surfactant protein (SP-A) mediates attachment of Mycobacterium tuberculosis to murine alveolar macrophages
83. SP-D stimulates phagocytosis of Pseudomonas aeruginosa by alveolar macrophages
84. Surfactant protein A stimulates actin polymerization in alveolar macrophages but not peripheral blood monocytes
85. Interactions of pulmonary surfactant protein D (SP-D) with human blood leukocytes
86. Surfactant proteins A and D specifically stimulate directed actin-based responses in alveolar macrophages
87. Surfactant-associated protein A inhibits LPS-induced cytokine and nitric oxide production in vivo
88. Surfactant protein A down-regulates proinflammatory cytokine production evoked by Candida albicans in human alveolar macrophages and monocytes
89. Induction of TNF-alpha release from human buffy coat cells by Pseudomonas aeruginosa is reduced by lung surfactant protein A
90. Surfactant protein A stimulation of inflammatory cytokine and immunoglobulin production
91. Surfactant protein A regulates cytokine production in the monocytic cell line THP-1
92. GM-CSF-deficient mice are susceptible to pulmonary group B Streptococcal infection
93. Surfactant protein-A-deficient mice are susceptible to Pseudomonas aeruginosa infection
94. Surfactant protein-A enhances respiratory syncytial virus clearance in vivo
95. Surfactant protein-D modulates lung inflammation with respiratory syncytial virus infection in vivo
96. SP-D expression regulates endotoxin mediated lung inflammation in vivo
97. Rat surfactant protein D enhances the production of oxygen radicals by rat alveolar macrophages
98. Surfactant protein A modulates release of reactive oxygen species from alveolar macrophages
99. Nittic oxide production by rat alveolar macrophages can be modulated in vitro by surfactant protein A
100. Effects of endotoxin on surfactant protein A and D stimulation of nitric oxide production by alveolar macrophages
101. Surfactant protein A mediates mycoplasmacidal activity of alveolar macrophages by production of peroxynitrite
102. Surfactant protein A suppresses reactive nitrogen intermediates by alveolar macrophages in response to Mycobacterium tuberculosis
103. Surfactant protein A enhances interferon γ-induced nitric oxide but inhibits LPS-induced nitric oxide alveolar macrophages
104. Recombinant SP-D carbohydrate recognition domain is a chemoattractant for human neutrophils
105. Site-directed mutagenesis of cys-15 and cys-20 of pulmonary surfactant protein D - Expression of a trimeric protein with altered anti-viral properties
106. Surfactant protein A, but not surfactant protein D, is an opsonin for influenza a virus phagocytosis by rat alveolar macrophages
107. Suppressive effects of SP-A on ionomycin-induced Il-8 production and release by eosinophils
108. Hyporesponsiveness of canine bronchoalveolar lymphocytes to mitogens: Inhibition of lymphocyte proliferation by alveolar macrophages
109. Immunosuppressive activity of canine pulmonary surface active material
110. Surfactant associated protein-A inhibits human lymphocyte proliferation and IL-2 production
111. Recombinant rat surfactant-associated protein D inhibits human T lymphocyte proliferation and IL-2 production
112. Surfactant protein A inhibits T cell proliferation via its collagen-like tail and a 210-kDa receptor
113. + cells
114. SP-A enhances viral clearance and inhibits inflammation after pulmonary adenoviral infection
115. Purification of a cell-surface receptor for surfactant protein A
116. SP-A enhances uptake of bacillus Calmette-Cuerin by macrophages through a specific SP-A receptor
117. Differential regulation of the mannose and SP-A receptors on macrophages
118. Functional aspects of the C1q receptors
119. Identification of the Raji cell membrane-derived C1q inhibitor as a receptor for human C1q
120. Human leukocyte C1q receptor binds other soluble proteins with collagen domains
121. Identification of a gC1q-binding protein (gC1q-R) on the surface of human neutrophils. Subcellular localization and binding properties in comparison with the cC1q-R
122. cDNA cloning and primary structure analysis of C1aRp, the human C1q/MBL/SPA receptor that mediated enhanced phagocytosis in vitro
123. C1qR(P) is a heavily O-glycosylated cell surface protein involved in the regulation of phagocytic activity
124. Interaction of C1q receptor with lung surfactant protein A
125. Binding of surfactant protein A to C1q receptors mediates the phagocytosis of Staphylococcus aureus by monocytes
126. Collectins, collectin receptors and the lectin pathway of complement activation
127. Pulmonary surfactant protein A modulates the cellular response to smooth and rough lipopolysaccharides by interaction with CD14
128. Surfactant protein A enhances the binding and deacylation of E. coli LPS by alveolar macrophages
129. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
130. Toll gates for pathogen selection
131. Surfactant protein-A binding proteins
132. SP-A-binding protein Bp55 is involved in surfactant endocytosis by Type II pneumocytes
133. Isolation and partial characterization of a receptor to surfactant protein A expressed by rat type II pneumocytes
134. Degradation of surfactant lipids and surfactant protein A by alveolar macrophages in vitro
135. Overexpression of surfactant protein SP-A, SP-B, and SP-C mRNA in rat lungs with lipopolysaccharide-induced injury
136. DMBT1 encodes a protein involved in the immune defense and in epithelial differentiation and is highly unstable in cancer
137. The genomic structure of the DMBT1 gene: Evidence for a region with susceptibility to genomic instability
138. Glycoprotein-340 binds surfactant protein-A (SP-A) and stimulates alveolar macrophage migration in an SP-A-independent manner
139. Surfactant proteins A and D bind CD14 by different mechanisms
140. Surfactant protein A is degraded by alveolar macrophages
141. Degradation of surfactant protein D by alveolar macrophages
142. Macrophages primed by overnight culture demonstrate a marked stimulation of surfactant protein A degradation
143. Characterization of pulmonary surfactant protein D: Its copurification with lipids
144. Effects of surfactant protein A and surfactant lipids on lymphocyte proliferation in vitro
145. Surfactant protein A stimulates phagocytosis of specific pulmonary pathogens by alveolar macrophages
146. Surfactant metabolism in surfactant protein Adeficient mice
147. Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice
148. Surfactant protein A-deficient mice are susceptible to group B streptococcal infection
149. Enhanced K. pneumoniae pulmonary infection in mice lacking SP-A
150. Surfactant protein-A binds group B Streptococcus enhancing phagocytosis and clearance from lungs of surfactant protein-A-deficient mice
151. In vivo structure/function analyses of surfactant protein A
152. Surfactant protein A mediates mycoplasmacidal activity of alveolar macrophages
153. Increased P. carinii infection in lungs of SP-A deficient mice
154. Increased lung inflammation in surfactant protein A deficient mice following acute adenoviral infection in vivo
155. Surfactant protein A protects growing cells and reduces TNF-alpha activity from LPS-stimulated macrophages
156. 2-terminal fragment with isolate LPS and intact Proteus mirabilis and Escherichia coli
157. Influence of CD14, LBP and BPI in the monocyte response to LPS of different polysaccharide chain length
158. A broadly cross-protective monoclonal antibody binding to Escherichia coli and Salmonella lipopolysaccharides
159. Competition between rBPI23, a recombinant fragment of bactericidal/permeability-increasing protein, and lipopolysaccharide (LPS)-binding protein for binding to LPS and gram-negative bacteria
160. Localization and developmental expression of surfactant proteins D and A in the respiratory tract of the mouse
161. SP-A2 gene expression in human fetal lung airways
162. Surfactant protein A2 gene expression by human airway submucosal gland cells
163. Pulmonary surfactant protein A (SP-A) is expressed by epithelial cells of small and large intestine
164. Surfactant protein A in rabbit sinus and middle ear mucosa
165. Expression of pulmonary surfactant protein D in rat gastric mucosa
166. Localization of lung surfactant protein D on mucosal surfaces in human tissue
167. Immunolocalization of SP-D in human secretory tissues
168. Both human SP-A1 and SP-A2 genes are expressed in small and large intestine
169. Collectin-mediated antiviral host defense of the lung - Evidence from influenza virus infection of mice
170. Surfactant proteins A and D increase in response to intratracheal lipopolysaccharide
171. Overexpression of surfacrant protein SP-A, SP-B, and SP-C mRNA in rat lungs with lipopolysaccharide-induced injury
172. Altered regulation of surfactant phospholipid and protein A during acute pulmonary inflammation
173. Lung epithelium-specific proteins
174. Cytokines and production of surfactant components
175. Altered regulation of surfactant phospholipid and protein A during acute pulmonary inflammation
176. Early alterations in intracellular and alveolar surfactant of the rat lung in response to endotoxin
177. Inhibitory effect of pulmonary surfactant proteins A and D on allergen-induced lymphocyte proliferation and histamine release in children with asthma
178. Surfactant protein D regulates surfactant phospholipid homeostasis in vivo
179. Decreased contents of surfactant proteins A and D in BAL fluids of healthy smokers
180. SP-A deficiency in primate model of bronchopulmonary dysplasia with infection. In situ mRNA and immunostains
181. Deficient hydrophilic lung surfactant proteins A and D with normal surfactant phospholipid molecular species in cystic fibrosis
182. Serial changes in surfactant-associated proteins in lung and serum before and after onset of ARDS
183. Surfactant protein A in bronchoalveolar lavage fluid
184. Pulmonary surfactant protein D in sera and bronchoalveolar lavage fluids
185. Surfactant protein-A concentration in bronchoalveolar lavage fluids of patients with pulmonary alveolar proteinosis
186. Mutations in the human mannose binding protein gene: Their frequencies in three distinct populations and relationship to serum levels of the protein
187. Molecular basis of opsonic defect in immunodeficient children
188. The role of collectins in host defense
189. Novel, nonradioactive, simple and multiplex PCR-cRLFP methods for genotyping human SP-A and SP-D marker alleles
190. Human SP-A locus: Allele frequencies and linkage disequilibrium between the two surfactant protein A genes
191. Recognition of Klebsiella pneumoniae by pulmonary C-type lectins
192. Opsonic activities of surfactant proteins A and D in phagocytosis of gram-negative bacteria by alveolar macrophages
193. Comparison of the opsonic activity of human surfactant protein A for Staphylococcus aureus and Streptococcus pneumoniae with rabbit and human macrophages