Effect of hydroxylation and N187-linked glycosylation on molecular and functional properties of recombinant human surfactant protein A

Biochemistry

Volumn 42, Issue 32, 2003, Pages 9532-9542

  Garcia Verdugo I ^a   Sanchez Barbero F ^a   Bosch, F U ^b   Steinhilber, W ^b   Casals, C ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b ALTANA PHARMA AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; COLLAGEN; CONFORMATIONS; FLUORESCENCE; HYDROXYLATION; OLIGOMERS; SURFACE ACTIVE AGENTS; THERMODYNAMIC STABILITY;

GLYCOSYLATION;

BIOCHEMISTRY;

ASPARAGINE; CALCIUM ION; COLLAGEN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLINE; RECOMBINANT HUMAN SURFACTANT PROTEIN A; SURFACTANT PROTEIN A; UNCLASSIFIED DRUG; CALCIUM; DIPALMITOYLPHOSPHATIDYLCHOLINE; LIPOPOLYSACCHARIDE; PHOSPHOLIPID; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISULFIDE BOND; FLUORESCENCE; GLYCOSYLATION; HUMAN; HUMAN TISSUE; HYDROXYLATION; INSECT CELL; MAMMAL CELL; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STABILITY; THERMOSTABILITY; ADSORPTION; ANIMAL; CELL LINE; CHEMISTRY; CHO CELL; COMPARATIVE STUDY; GENETICS; HAMSTER; HEAT; INSECT; KINETICS; METABOLISM; PHYSIOLOGY; PROTEIN DENATURATION; PROTEIN TERTIARY STRUCTURE;

ANIMALIA; INSECTA; MAMMALIA;

1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE; ADSORPTION; ANIMALS; CALCIUM; CELL LINE; CHO CELLS; CRICETINAE; GLYCOSYLATION; HEAT; HUMANS; HYDROXYLATION; INSECTS; KINETICS; LIPOPOLYSACCHARIDES; PHOSPHOLIPIDS; PROTEIN DENATURATION; PROTEIN STRUCTURE, TERTIARY; PULMONARY SURFACTANT-ASSOCIATED PROTEIN A; RECOMBINANT PROTEINS;

EID: 0041525581     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0347196     Document Type: Article

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