Control of the DNA damage checkpoint by Chk1 and Rad53 protein kinases through distinct mechanisms

Science

Volumn 286, Issue 5442, 1999, Pages 1166-1171

  Sanchez, Yolanda ^a   Bachant, Jeff ^a   Wang, Hong ^a   Hu, Fenghua ^a   Liu, Dou ^a   Tetzlaff, Michael ^a   Elledge, Stephen J ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

INHIBITOR PROTEIN; PROTEIN KINASE;

ANAPHASE; ARTICLE; DNA DAMAGE; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

ANAPHASE; CDC2 PROTEIN KINASE; CELL CYCLE PROTEINS; CYCLIN B; DNA DAMAGE; DNA, FUNGAL; FUNGAL PROTEINS; LIGASES; MITOSIS; MUTATION; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT FUSION PROTEINS; RNA-BINDING PROTEINS; S PHASE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; UBIQUITIN-PROTEIN LIGASE COMPLEXES; UBIQUITIN-PROTEIN LIGASES;

MAMMALIA; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE;

EID: 0033527787     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.286.5442.1166     Document Type: Article

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31. We thank A. Murray, A. Straight, T. Weinert, D. Gottschling, O. Cohen-Fix, D. Koshland, V. Lundblad, M. Yanagida, U. Surana, L. Hartwelt, D. Toczyski, and A. Amon for providing reagents and helpful information; C. Nugent, C. Tomlinson, and M. Kuroda for helpful comments on the manuscript; and D. Honican and M. Li for excellent technical assistance. Y.S. and J.B. were supported by NIH postdoctoral fellowships. Supported by grants GM44664 and Q1187 (Welch) to S.J.E. S.J.E is an investigator with the Howard Hughes Medical Institute.