Drosophila grapes/CHK1 mutants are defective in cyclin proteolysis and coordination of mitotic events

Current Biology

Volumn 9, Issue 16, 1999, Pages 919-922

  Su, Tin Tin ^a,b   Campbell, Shelagh D ^c   O'Farrell, Patrick H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DROSOPHILA; SCHIZOSACCHAROMYCES POMBE;

EID: 0033606968     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(99)80399-6     Document Type: Article

References (11)

1. Sibon OC, Stevenson VA, Theurkauf WE: DNA-replication checkpoint control at the Drosophila midblastula transition. Nature 1997, 388:93-97.
2. Fogarty P, Kalpin RF, Sullivan W: The Drosophila maternal-effect mutation grapes causes a metaphase arrest at nuclear cycle 13. Development 1994, 120:2131-2142.
3. Fogarty P, Campbell SD, Abu-Shumays R, Phalle BS, Yu KR, Uy GL, et al.: The Drosophila grapes gene is related to checkpoint gene chk1/rad27 and is required for late syncytial division fidelity. Curr Biol 1997, 7:418-426.
4. Peng CY, Graves PR, Thoma RS, Wu Z, Shaw AS, Piwnica-Worms H: Mitotic and G2 checkpoint control: Regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science 1997, 277:1501-1505.
5. Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, et al.: Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25. Science 1997, 277:1497-1501.
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8. Su TT, Sprenger F, DiGregorio PJ, Campbell SD, O'Farrell PH: Exit from mitosis in Drosophila syncytial embryos requires proteolysis and cyclin degradation, and is associated with localized dephosphorylation. Genes Dev 1998, 12:1495-1503.
9. Sibon OC, Laurencon A, Hawley R, Theurkauf WE: The Drosophila ATM homologue Mei-41 has an essential checkpoint function at the midblastula transition. Curr Biol 1999, 9:302-312.
10. Lopez-Girona A, Furnari B, Mondesert O, Russell P: Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein. Nature 1999, 397:172-175.
11. Russell P: Checkpoints on the road to mitosis. Trends Biochem Sci 1998, 23:399-402.