메뉴 건너뛰기




Volumn 10, Issue 4, 1999, Pages 213-222

Heterozygosity of p21(WAF1/CIP1) enhances tumor cell proliferation and cyclin D1-associated kinase activity in a murine mammary cancer model

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; PROTEIN P21; BROXURIDINE; CDKN1A PROTEIN, MOUSE; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1A; PHOSPHOTRANSFERASE;

EID: 0032587889     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (41)

References (51)
  • 1
    • 0029808466 scopus 로고    scopus 로고
    • Cell cycle checkpoints: Preventing an identity crisis
    • Elledge, S. J. Cell cycle checkpoints: preventing an identity crisis. Science (Washington DC), 274: 1664-1672, 1996.
    • (1996) Science (Washington DC) , vol.274 , pp. 1664-1672
    • Elledge, S.J.1
  • 2
    • 0024425887 scopus 로고
    • Checkpoints: Controls that ensure the order of cell cycle events
    • Hartwell, L. H., and Weinert, T. A. Checkpoints: controls that ensure the order of cell cycle events. Science (Washington DC), 246: 629-634, 1989.
    • (1989) Science (Washington DC) , vol.246 , pp. 629-634
    • Hartwell, L.H.1    Weinert, T.A.2
  • 5
    • 0031951182 scopus 로고    scopus 로고
    • Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes
    • Lundberg, A. S., and Weinberg, R. A. Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. Mol. Cell. Biol., 18: 753-761, 1998.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 753-761
    • Lundberg, A.S.1    Weinberg, R.A.2
  • 6
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr, C. J. Cancer cell cycles. Science (Washington DC), 274: 1672-1677, 1996.
    • (1996) Science (Washington DC) , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 7
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg, R. A. The retinoblastoma protein and cell cycle control. Cell, 81: 323-330, 1995.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 14
    • 0028963841 scopus 로고
    • P53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage
    • Macleod, K. F., Sherry, N., Hannon, G., Beach, D., Tokino, T., Kinzler, K., Vogelstein, B., and Jacks, T. P53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev., 9: 935-944, 1995.
    • (1995) Genes Dev. , vol.9 , pp. 935-944
    • Macleod, K.F.1    Sherry, N.2    Hannon, G.3    Beach, D.4    Tokino, T.5    Kinzler, K.6    Vogelstein, B.7    Jacks, T.8
  • 17
    • 0031961995 scopus 로고    scopus 로고
    • 2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication
    • 2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication. Mol. Cell. Biol., 18: 629-643, 1998.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 629-643
    • Niculescu A.B. III1    Chen, X.2    Smeets, M.3    Hengst, L.4    Prives, C.5    Reed, S.I.6
  • 18
    • 0032190833 scopus 로고    scopus 로고
    • Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression
    • Bates, S., Ryan, K. M., Phillips, A. C., and Vousden, K. H. Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression. Oncogene, 17: 1691-1703, 1998.
    • (1998) Oncogene , vol.17 , pp. 1691-1703
    • Bates, S.1    Ryan, K.M.2    Phillips, A.C.3    Vousden, K.H.4
  • 20
    • 0028169236 scopus 로고
    • p21-containing cyclin kinases exist in both active and inactive states
    • Zhang, H., Hannon, G. J., and Beach, D. p21-containing cyclin kinases exist in both active and inactive states. Genes Dev., 8: 1750-1758, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 1750-1758
    • Zhang, H.1    Hannon, G.J.2    Beach, D.3
  • 22
    • 0032535375 scopus 로고    scopus 로고
    • Complete inhibition of Cdk/cyclin by one molecule of p21(Cip1)
    • Hengst, L., Gopfert, U., Lashuel, H. A., and Reed, S. I. Complete inhibition of Cdk/cyclin by one molecule of p21(Cip1). Genes Dev., 12: 3882-3888, 1998.
    • (1998) Genes Dev. , vol.12 , pp. 3882-3888
    • Hengst, L.1    Gopfert, U.2    Lashuel, H.A.3    Reed, S.I.4
  • 24
    • 0028820762 scopus 로고
    • The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo
    • Yang, Z. Y., Perkins, N. D., Ohno, T., Nabel, E. G., and Nabel, G. J. The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo. Nat. Med., 1: 1052-1056, 1995.
    • (1995) Nat. Med. , vol.1 , pp. 1052-1056
    • Yang, Z.Y.1    Perkins, N.D.2    Ohno, T.3    Nabel, E.G.4    Nabel, G.J.5
  • 26
    • 0029666272 scopus 로고    scopus 로고
    • WAF1/CIP1/SDI1 mutant (Arg94 → Trp) identified in a human breast carcinoma. Evidence that the mutation impairs the ability of p21 to inhibit cyclin-dependent kinases
    • WAF1/CIP1/SDI1 mutant (Arg94 → Trp) identified in a human breast carcinoma. Evidence that the mutation impairs the ability of p21 to inhibit cyclin-dependent kinases. J. Biol. Chem., 271: 15782-15786, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15782-15786
    • Balbin, M.1    Hannon, G.J.2    Pendas, A.M.3    Ferrando, A.A.4    Vizoso, F.5    Fueyo, A.6    Lopez-Otin, C.7
  • 27
    • 0028845577 scopus 로고
    • Somatic mutations of the WAF1/CIP1 gene in primary prostate cancer
    • Gao, X., Chen, Y. Q., Wu, N., Grignon, D. J., Sakr, W., Porter, A. T., and Honn, K. V. Somatic mutations of the WAF1/CIP1 gene in primary prostate cancer. Oncogene, 11: 1395-1398, 1995.
    • (1995) Oncogene , vol.11 , pp. 1395-1398
    • Gao, X.1    Chen, Y.Q.2    Wu, N.3    Grignon, D.J.4    Sakr, W.5    Porter, A.T.6    Honn, K.V.7
  • 31
    • 0029658030 scopus 로고    scopus 로고
    • The absence of p21CIP1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression
    • Missero, C., Di Cunto, F., Kiyokawa, H., Koff, A., and Paolo Dotto, G. The absence of p21CIP1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression. Genes Dev., 10: 3065-3075, 1996.
    • (1996) Genes Dev. , vol.10 , pp. 3065-3075
    • Missero, C.1    Di Cunto, F.2    Kiyokawa, H.3    Koff, A.4    Paolo Dotto, G.5
  • 32
    • 0031474756 scopus 로고    scopus 로고
    • Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice
    • Wang, Y. A., Elson, A., and Leder, P. Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice. Proc. Natl. Acad. Sci. USA, 94: 14590-14595, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14590-14595
    • Wang, Y.A.1    Elson, A.2    Leder, P.3
  • 33
    • 0032563286 scopus 로고    scopus 로고
    • Cleavage of CDK inhibitor p21(Cip1/Waf1) by caspases is an early event during DNA damage-induced apoptosis
    • Gervais, J. L., Seth, P., and Zhang, H. Cleavage of CDK inhibitor p21(Cip1/Waf1) by caspases is an early event during DNA damage-induced apoptosis. J. Biol. Chem., 273: 19207-19212, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 19207-19212
    • Gervais, J.L.1    Seth, P.2    Zhang, H.3
  • 34
    • 0029811984 scopus 로고    scopus 로고
    • Genetic determinants of p53-induced apoptosis and growth arrest
    • Polyak, K., Waldman, T., He, T. C., Kinzler, K. W., and Vogelstein, B. Genetic determinants of p53-induced apoptosis and growth arrest. Genes Dev., 10: 1945-1952, 1996.
    • (1996) Genes Dev. , vol.10 , pp. 1945-1952
    • Polyak, K.1    Waldman, T.2    He, T.C.3    Kinzler, K.W.4    Vogelstein, B.5
  • 35
    • 0024162530 scopus 로고
    • Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice
    • Tsukamoto, A. S., Grosschedl, R., Guzman, R. C., Parslow, T., and Varmus, H. E. Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell, 55: 619-625, 1988.
    • (1988) Cell , vol.55 , pp. 619-625
    • Tsukamoto, A.S.1    Grosschedl, R.2    Guzman, R.C.3    Parslow, T.4    Varmus, H.E.5
  • 36
    • 0002494370 scopus 로고
    • Morphology of mammary tumors in mice
    • F. Homburger (ed.), New York: Hoeber
    • Dunn, T. B. Morphology of mammary tumors in mice. In: F. Homburger (ed.), The Physiopathology of Cancer, pp. 38-84. New York: Hoeber, 1959.
    • (1959) The Physiopathology of Cancer , pp. 38-84
    • Dunn, T.B.1
  • 37
    • 0028252414 scopus 로고
    • Tumors of the mammary gland
    • V. Turosov and U. Mohr (eds.), London: Oxford University Press
    • Squartini, F., and Pingitore, R. Tumors of the mammary gland. In: V. Turosov and U. Mohr (eds.), Pathology of Tumors in Laboratory Animals, Vol. 2, pp. 47-100. London: Oxford University Press, 1994.
    • (1994) Pathology of Tumors in Laboratory Animals , vol.2 , pp. 47-100
    • Squartini, F.1    Pingitore, R.2
  • 38
    • 0029677188 scopus 로고    scopus 로고
    • The biology of mammary transgenes: Five rules
    • Cardiff, R. D. The biology of mammary transgenes: five rules. J. Mamm. Gland Biol. Neoplasia, 1: 61-73, 1996.
    • (1996) J. Mamm. Gland Biol. Neoplasia , vol.1 , pp. 61-73
    • Cardiff, R.D.1
  • 39
    • 0032617467 scopus 로고    scopus 로고
    • The comparative pathology of human and mouse mammary glands
    • in press
    • Cardiff, R. D., and Wellings, S. R. The comparative pathology of human and mouse mammary glands. J. Mamm. Gland Biol. Neoplasia, in press, 1999.
    • (1999) J. Mamm. Gland Biol. Neoplasia
    • Cardiff, R.D.1    Wellings, S.R.2
  • 42
    • 0030902111 scopus 로고    scopus 로고
    • p21(Waf1/Cip1) protects against p53-mediated apoptosis of human melanoma cells
    • Gorospe, M., Cirielli, C., Wang, X., Seth, P., Capogrossi, M. C., and Holbrook, N. J. p21(Waf1/Cip1) protects against p53-mediated apoptosis of human melanoma cells. Oncogene, 14: 929-935, 1997.
    • (1997) Oncogene , vol.14 , pp. 929-935
    • Gorospe, M.1    Cirielli, C.2    Wang, X.3    Seth, P.4    Capogrossi, M.C.5    Holbrook, N.J.6
  • 43
    • 0032537819 scopus 로고    scopus 로고
    • Signals from Ras and Rho GTPases interact to regulate expression of p21Wafl/Cip1
    • Olson, M. F., Paterson, H. F., and Marshall, C. J. Signals from Ras and Rho GTPases interact to regulate expression of p21Wafl/Cip1. Nature (Lond.), 394: 295-299, 1998.
    • (1998) Nature (Lond.) , vol.394 , pp. 295-299
    • Olson, M.F.1    Paterson, H.F.2    Marshall, C.J.3
  • 44
    • 0030871667 scopus 로고    scopus 로고
    • High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1
    • Sewing, A. B., Wiseman, B., Lloyd, A. C., and Land, H. High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1. Mol. Cell. Biol., 17: 5588-5597, 1997.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5588-5597
    • Sewing, A.B.1    Wiseman, B.2    Lloyd, A.C.3    Land, H.4
  • 45
    • 0027363063 scopus 로고
    • Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse
    • Dietrich, W. F., Lander, E. S., Smith, J. S., Moser, A. R., Gould, K. A., Luongo, C., Borenstein, N., and Dove, W. F. Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse. Cell, 75: 631-639, 1993.
    • (1993) Cell , vol.75 , pp. 631-639
    • Dietrich, W.F.1    Lander, E.S.2    Smith, J.S.3    Moser, A.R.4    Gould, K.A.5    Luongo, C.6    Borenstein, N.7    Dove, W.F.8
  • 46
    • 0030265301 scopus 로고    scopus 로고
    • Manipulation of the mouse germline in the study of Min-induced neoplasia
    • Bilger, A., Shoemaker, A. R., Gould, K. A., and Dove, W. F. Manipulation of the mouse germline in the study of Min-induced neoplasia. Semin. Cancer Biol., 7: 249-260, 1996.
    • (1996) Semin. Cancer Biol. , vol.7 , pp. 249-260
    • Bilger, A.1    Shoemaker, A.R.2    Gould, K.A.3    Dove, W.F.4
  • 47
    • 0028898335 scopus 로고
    • Chromosomal mapping of the genes for the human cell cycle proteins cyclin C (CCNC), cyclin E (CCNE), p21 (CDKN1) and KAP (CDKN3)
    • Demetrick, D. J., Matsumoto, S., Hannon, G. J., Okamoto, K., Xiong, Y., Zhang, H., and Beach, D. Chromosomal mapping of the genes for the human cell cycle proteins cyclin C (CCNC), cyclin E (CCNE), p21 (CDKN1) and KAP (CDKN3). Cytogenet. Cell Genet., 69: 190-192, 1995.
    • (1995) Cytogenet. Cell Genet. , vol.69 , pp. 190-192
    • Demetrick, D.J.1    Matsumoto, S.2    Hannon, G.J.3    Okamoto, K.4    Xiong, Y.5    Zhang, H.6    Beach, D.7
  • 48
    • 0027408255 scopus 로고
    • Frequent loss of heterozygosity on chromosome 6 in human ovarian carcinoma
    • Foulkes, W. D., Ragoussis, J., Stamp, G. W., Allan, G. J., and Trowsdale, J. Frequent loss of heterozygosity on chromosome 6 in human ovarian carcinoma. Br. J. Cancer, 67: 551-559, 1993.
    • (1993) Br. J. Cancer , vol.67 , pp. 551-559
    • Foulkes, W.D.1    Ragoussis, J.2    Stamp, G.W.3    Allan, G.J.4    Trowsdale, J.5
  • 49
    • 0029890634 scopus 로고    scopus 로고
    • Allelic losses at chromosomes 1p, 2p, 6p, 10p, 13q, 17p, and 21q significantly correlate with the chromophobe subtype of renal cell carcinoma
    • Schwerdtle, R. F., Storkel, S., Neuhaus, C., Brauch, H., Weidt, E., Brenner, W. R., Hohenfellner, R., Huber, C., and Decker, H. J. Allelic losses at chromosomes 1p, 2p, 6p, 10p, 13q, 17p, and 21q significantly correlate with the chromophobe subtype of renal cell carcinoma. Cancer Res., 56: 2927-2930, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 2927-2930
    • Schwerdtle, R.F.1    Storkel, S.2    Neuhaus, C.3    Brauch, H.4    Weidt, E.5    Brenner, W.R.6    Hohenfellner, R.7    Huber, C.8    Decker, H.J.9
  • 51
    • 0023750023 scopus 로고
    • Dominance of a tumor subpopulation in mixed heterogeneous mouse mammary tumors
    • Miller, B. E., Miller, F. R., Wibum, D., and Heppner, G. H. Dominance of a tumor subpopulation in mixed heterogeneous mouse mammary tumors. Cancer Res., 48: 5747-5753, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 5747-5753
    • Miller, B.E.1    Miller, F.R.2    Wibum, D.3    Heppner, G.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.