Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage

Stem Cells

Volumn 23, Issue 4, 2005, Pages 516-529

  Armstrong, L ^a,c   Saretzki, G ^b   Peters, H ^c   Wappler, I ^c   Evans, J ^c   Hole, N ^a   Von Zglinicki, T ^b   Lako, Majlinda ^c,d  

^a DURHAM UNIVERSITY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d INSTITUTE OF HUMAN GENETICS   (United Kingdom)

Author keywords

Apoptosis; Cell cycle; Cell proliferation; ESCs; Hematopoietic stem cells; Oxidative stress; Telomerase

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE; DNA; TELOMERASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; COLONY FORMING UNIT GEMM; CONTROLLED STUDY; DNA DAMAGE; DNA MICROARRAY; DNA REPAIR; EMBRYO; EMBRYONIC STEM CELL; FLOW CYTOMETRY; GENE OVEREXPRESSION; HEMATOPOIESIS; KARYOTYPE; MOUSE; NONHUMAN; OXIDATIVE STRESS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; TELOMERE; TELOMERIC REPEAT AMPLIFICATION PROTOCOL;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; EMBRYO; HEMATOPOIESIS; MICE; OXIDATIVE STRESS; STEM CELLS; TELOMERASE;

ANIMALIA; MURINAE;

EID: 16444384725     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2004-0269     Document Type: Article

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