Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation

Nature Genetics

Volumn 26, Issue 1, 2000, Pages 85-88

  Wong, Kwok Kin ^a   Chang, Sandy ^a,b   Weiler, Sarah R ^a   Ganesan, Shridar ^a   Chaudhuri, Jayanta ^c   Zhu, Chengming ^c   Artandi, Steven E ^a   Rudolph, Karl Lenhard ^a   Gottlieb, Geoffrey J ^d   Chin, Lynda ^a,c   Alt, Frederick W ^c,e   DePinho, Ronald A ^a,c  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d QUEST DIAGNOSTICS NICHOLS INSTITUTE   (United States)

^e BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOPROTEIN;

APOPTOSIS; ARTICLE; CELL VIABILITY; CHROMOSOME ABERRATION; CHROMOSOME BREAKAGE; CONTROLLED STUDY; DNA REPAIR; ENZYME ACTIVITY; IONIZING RADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIVITY; TELOMERE;

ANIMALS; APOPTOSIS; CELL NUCLEUS; CELL SURVIVAL; CHROMOSOME ABERRATIONS; CHROMOSOMES; DNA FRAGMENTATION; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, RADIATION; FIBROBLASTS; GENOTYPE; IN SITU NICK-END LABELING; KINETICS; MICE; MICE, TRANSGENIC; MODELS, GENETIC; RADIATION TOLERANCE; RADIATION, IONIZING; TELOMERE; THYMUS GLAND; TIME FACTORS;

EUKARYOTA;

EID: 0033822365     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/79232     Document Type: Article

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