Telomerase activity in candidate stem cells from fetal liver and adult bone marrow

Blood

Volumn 91, Issue 9, 1998, Pages 3255-3262

  Yui, Jane ^b   Chiu, Choy Pik ^b   Lansdorp, Peter M ^a  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

RIBONUCLEOPROTEIN; TELOMERASE;

ARTICLE; B LYMPHOCYTE ACTIVATION; BONE MARROW CELL; CELL IMMORTALIZATION; CELL PROLIFERATION; DNA REPLICATION; DNA TEMPLATE; ENZYME ACTIVITY; FETUS LIVER; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; RNA SEQUENCE; STEM CELL; T LYMPHOCYTE ACTIVATION; TELOMERE;

EID: 0032080191     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.9.3255.3255_3255_3262     Document Type: Article

References (50)

1. Blackburn EH: Telomeres: No end in sight. Cell 77:621, 1994
2. Zakian VA: Telomeres: Beginning to understand the end. Science 270:1601, 1995
3. Harley CB, Futcher AB, Greider CW: Telomeres shorten during ageing of human fibroblasts. Nature 345:458, 1990
4. Allsopp RC, Vaziri H, Patterson C, Goldstein S, Younglai EV, Futcher AB, Greider CW, Harley CB: Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci USA 89:10114, 1992
5. Vaziri H, Schachter F, Uchida I, Wei L, Zhu X, Effros R, Cohen D, Harley CB: Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am J Hum Genet 52:661, 1993
6. Vaziri H, Dragowska W, Allsopp RC, Thomas TE, Harley CB, Lansdorp PM: Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age. Proc Natl Acad Sci USA 91:9857, 1994
7. Levy MZ, Allsopp RC, Futcher AB, Greider CW, Harley CB: Telomere end-replication problem and cell aging. J Mol Biol 225:951, 1992
8. Lingner J, Cooper JP, Cech TR: Telomerase and DNA end replication: No longer a lagging strand problem? Science 269:1533, 1995
9. Harley CB: Telomere loss: Mitotic clock or genetic time bomb? Mutat Res 256:271, 1991
10. Greider CW, Blackburn EH: A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature 337:331, 1989
11. Singer MS, Gottschling DE: TLC1: Template RNA component of Saccharomyces cerevisiae telomerase. Science 266:404, 1994
12. McEachern MJ, Blackburn EH: Runaway telomere elongation caused by telomerase RNA gene mutations. Nature 376:403, 1995
13. Blasco MA, Funk W, Villeponteau B, Greider CW: Functional characterization and developmental regulation of mouse telomerase RNA. Science 269:1267, 1995
14. Feng J, Funk WD, Wang S-S, Weinrich SL, Avilion AA, Chiu C-P, Adams RR, Chang E, Allsopp RC, Yu J, Le S, West MD, Harley CB, Andrews WH, Greider CW, Villeponteau B: The RNA component of human telomerase. Science 269:1236, 1995
15. Nakamura TM, Morin GB, Chapman KB, Weinrich SL, Andrews WH, Lingner J, Harley CB, Cech TR: Telomerase catalytic subunit homologs from fission yeast and human. Science 277:955, 1997
16. Meyerson M, Counter CM, Eaton EN, Ellisen LW, Steiner P, Dickinson Caddie S, Ziaugra L, Beijersbergen RL, Davidoff MJ, Liu Q, Bacchetti S, Haber DA, Weinberg RA: hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell 90:785, 1997
17. Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PLC, Coviello GM, Wright WE, Weinrich SL, Shay JW: Specific association of human telomerase activity with immortal cells and cancer. Science 266:2011, 1994
18. Wright WE, Piatyszek MA, Rainey WE, Byrd W, Shay JW: Telomerase activity in human germline and embryonic tissues and cells. Dev Genet 18:173, 1996
19. Counter CM, Hirte HW, Bacchetti S, Harley CB: Telomerase activity in human ovarian carcinoma. Proc Natl Acad Sci USA 91:2900, 1994
20. Hiyama E, Gollahon L, Kataoka T, Kuroi K, Yokoyama T, Gazdar AF, Hiyama K, Piatyszek MA, Shay JW: Telomerase activity in human breast tumors. J Natl Cancer Inst 88:116, 1996
21. Tahara H, Nakanishi T, Kitamoto M, Nakashio R, Shay JW, Tahara E, Kajiyama G, Ide T: Telomerase activity in human liver tissues: Comparison between chronic liver disease and hepatocellular carcinomas. Cancer Res 55:2734, 1995
22. Hiyama K, Hiyama E, Ishioka S, Yamakido M, Inai K, Gazdar AF, Piatyszek MA, Shay JW: Telomerase activity in small-cell and non-small-cell lung cancers. J Natl Cancer Inst 87:895, 1995
23. Sommerfeld HJ, Meeker AK, Piatyszek MA, Bova GS, Shay JW, Coffey DS: Telomerase activity: A prevalent marker of malignant human prostate tissue. Cancer Res 56:218, 1996
24. Hiyama E, Hiyama K, Yokoyama T, Matsuura Y, Piatyszek MA, Shay JW: Correlating telomerase activity levels with human neuroblastoma outcomes. Nat Med 1:249, 1995
25. Nilsson P, Mehle C, Remes K, Roos G: Telomerase activity in vivo in human malignant hematopoietic cells. Oncogene 9:3043, 1994
26. Counter CM, Gupta J, Harley CB, Leber B, Bacchetti S: Telomerase activity in normal leukocytes and in hematologie malignancies. Blood 85:2315, 1995
27. Broccoli D, Young JW, de Lange T: Telomerase activity in normal and malignant hematopoietic cells. Proc Natl Acad Sci USA 92:9082, 1995
28. Chiu C-P, Dragowska W, Kim NW, Vaziri H, Yui J, Thomas TE, Harley CB, Lansdorp PM: Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow. Stem Cells 14:239, 1996
29. Hiyama K, Hirai Y, Kyoizumi S, Akiyama M, Hiyama E, Piatyszek MA, Shay JW, Ishioka S, Yamakido M: Activation of telomerase in human lymphocytes and hematopoietic progenitor cells. J Immunol 155:3711, 1995
30. Lansdorp PM, Dragowska W: Maintenance of hematopoiesis in serum-free bone marrow cultures involves sequential recruitment of quiescent progenitors. Exp Hematol 21:1321, 1993
31. Lansdorp PM: Self renewal of stem cells. Biol Blood Marrow Transplant 3:171, 1997
32. Lansdorp PM, Dragowska W: Long-term erythropoiesis from constant numbers of CD34+ cells in serum-free cultures initiated with highly purified progenitor cells from human bone marrow. J Exp Med 175:1501, 1992
33. Lansdorp PM, Dragowska W, Mayani H: Ontogeny-related changes in proliferative potential of human hematopoietic cells. J Exp Med 178:787, 1993
34. + hematopoietic progenitor cells from maternal peripheral blood. Blood 89:2347, 1997
35. Weng N-P, Levine BL, June CH, Hodes RJ: Regulated expression of telomerase activity in human T lymphocyte development and activation. J Exp Med 183:2471, 1996
36. Igarashi H, Sakaguchi N: Telomerase activity is induced by the stimulation to antigen receptor in human peripheral lymphocytes. Biochem Biophys Res Commun 219:649, 1996
37. Buchkovich KJ, Greider CW: Telomerase regulation during entry into the cell cycle in normal human T cells. Mol Biol Cell 7:1443, 1996
38. Sutherland HJ, Eaves CJ, Eaves AC, Dragowska W, Lansdorp PM: Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro. Blood 74:1563, 1989
39. + subpopulations of human bone marrow cells. Proc Natl Acad Sci USA 91:12223, 1994
40. Holt SE, Wrighl WE, Shay JW: Regulation of telomerase activity in immortal cell lines. Mol Cell Biol 16:2932, 1996
41. Sharma HW, Sokoloski JA, Perez JR, Maltese JY, Sartorelli AC, Stein CA, Niehols G, Khaled Z, Telang NT, Narayanan R: Differentiation of immortal cells inhibits telomerase activity. Proc Natl Acad Sci USA 92:12343, 1995
42. Biasco MA, Rizen M, Greider CW, Hanahan D: Differential regulation of telomerase activity and telomerase RNA during multistage tumorigenesis. Nat Genet 12:200, 1996
43. Broccoli D, Godley LA, Donehower LA, Varmus HE, de Lange T: Telomerase activation in mouse mammary tumors: Lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation. Mol Cell Biol 16:3765, 1996
44. Biasco MA, Lee H-W, Hande MP, Samper E, Lansdorp PM, DePinho RA, Greider CW: Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91:25, 1997
45. Harle-Bachor C, Boukamp P: Telomerase activity in the regenerative basal layer of the epidermis in human skin and in immortal and carcinoma-derived skin keratinocytes. Proc Natl Acad Sci USA 93: 6476, 1996
46. Yasumoto S, Kunimura C, Kikuchi K, Tahara H, Ohji H, Yamamoto H, Ide T, Utakoji T: Telomerase activity in normal human epithelial cells. Oncogene 13:433, 1996
47. Holt SE, Shay JW, Wright WE: Refining the telomere-telomerase hypothesis of aging and cancer. Nat Biotechnol 14:834, 1996
48. Morrison SJ, Prowse KR, Ho P, Weissman IL: Telomerase activity in hematopoietic cells is associated with self-renewal potential. Immunity 5:207, 1996
49. Prowse KR, Greider CW: Developmental and tissue-specific regulation of mouse telomerase and telomere length. Proc Natl Acad Sci USA 92:4818, 1995
50. Lansdorp PM, Verwoerd NP, van de Rijke FM, Dragowska V, Little M-T, Dirks RW, Raap AK, Tanke HJ: Heterogeneity in telomere length of human chromosomes. Hum Mol Genet 5:685, 1996