-
1
-
-
0033399453
-
Anticancer drug targets: Cell cycle and checkpoint control
-
Shapiro, G. I., and Harper, J. W. Anticancer drug targets: cell cycle and checkpoint control. J. Clin. Investig., 104: 1645-1653, 1999. (Pubitemid 30053178)
-
(1999)
Journal of Clinical Investigation
, vol.104
, Issue.12
, pp. 1645-1653
-
-
Shapiro, G.I.1
Harper, J.W.2
-
2
-
-
0031918742
-
The mitochondrial death/life regulator in apoptosis and necrosis
-
DOI 10.1146/annurev.physiol.60.1.619
-
Kroemer, G., Dallaporta, B., and Resche-Rigon, M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu. Rev. Physiol., 60: 619-642, 1998. (Pubitemid 28157889)
-
(1998)
Annual Review of Physiology
, vol.60
, pp. 619-642
-
-
Kroemer, G.1
Dallaporta, B.2
Resche-Rigon, M.3
-
3
-
-
0035797881
-
Apoptotic cell removal
-
DOI 10.1016/S0960-9822(01)00474-2
-
Henson, P. M., Bratton, D. L., and Fadok, V. A. Apoptotic cell removal. Curr. Biol., 11: R795-R805, 2001. (Pubitemid 32931008)
-
(2001)
Current Biology
, vol.11
, Issue.19
-
-
Henson, P.M.1
Bratton, D.L.2
Fadok, V.A.3
-
4
-
-
0036463405
-
A matter of life and death
-
DOI 10.1016/S1535-6108(02)00024-7
-
Green, D. R., and Evan, G. I. A matter of life and death. Cancer Cell, 1: 19-30, 2002. (Pubitemid 41039172)
-
(2002)
Cancer Cell
, vol.1
, Issue.1
, pp. 19-30
-
-
Green, D.R.1
Evan, G.I.2
-
5
-
-
0035902115
-
Proliferation, cell cycle and apoptosis in cancer
-
DOI 10.1038/35077213
-
Evan, G. I., and Vousden, K. H. Proliferation, cell cycle and apoptosis in cancer. Nature (Lond.), 411: 342-348, 2001. (Pubitemid 32467043)
-
(2001)
Nature
, vol.411
, Issue.6835
, pp. 342-348
-
-
Evan, G.I.1
Vousden, K.H.2
-
6
-
-
0032785021
-
Caspase structure, proteolytic substrates, and function during apoptotic cell death
-
Nicholson, D. Caspase structure, proteolytic substrates, and function during apoptotic cell death. Cell Death Differ., 11: 1028-1042, 1999.
-
(1999)
Cell Death Differ.
, vol.11
, pp. 1028-1042
-
-
Nicholson, D.1
-
7
-
-
0034615555
-
Caspases - Controlling intracellular signals by protease zymogen activation
-
DOI 10.1016/S0167-4838(99)00281-2, PII S0167483899002812
-
Stennicke, H., and Salvesen, G. Caspases: controlling intracellular signals by protease zymogen activation. Biochim. Biophys. Acta, 1477: 299-306, 2000. (Pubitemid 30119908)
-
(2000)
Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology
, vol.1477
, Issue.1-2
, pp. 299-306
-
-
Stennicke, H.R.1
Salvesen, G.S.2
-
8
-
-
0032491577
-
Caspase-14 is a novel developmentally regulated protease
-
DOI 10.1074/jbc.273.45.29648
-
Hu, S., Snipas, S. J., Vincenz, C., Salvesen, G., and Dixit, V. M. Caspase-14 is a novel developmentally regulated protease. J. Biol. Chem., 273: 29648-29653, 1998. (Pubitemid 28509974)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.45
, pp. 29648-29653
-
-
Hu, S.1
Snipas, S.J.2
Vincenz, C.3
Salvesen, G.4
Dixit, V.M.5
-
9
-
-
0032533841
-
Identification and characterization of murine caspase-14, a new member of the caspase family
-
Ahmad, M., Srinivasula, S. M., Hegde, R., Mukattash, R., Fernandes-Alnemri, T., and Alnemri, E. S. Identification and characterization of murine caspase-14, a new member of the caspase family. Cancer Res., 58: 5201-5205, 1998. (Pubitemid 28521183)
-
(1998)
Cancer Research
, vol.58
, Issue.22
, pp. 5201-5205
-
-
Ahmad, M.1
Srinivasula, S.M.2
Hegde, R.3
Mukattash, R.4
Fernandes-Alnemri, T.5
Alnemri, E.S.6
-
10
-
-
0035936797
-
The TNF and TNF receptor superfamilies: Integrating mammalian biology
-
DOI 10.1016/S0092-8674(01)00237-9
-
Locksley, R. M., Killeen, N., and Lenardo, M. J. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell, 104: 487-501, 2001. (Pubitemid 32201945)
-
(2001)
Cell
, vol.104
, Issue.4
, pp. 487-501
-
-
Locksley, R.M.1
Killeen, N.2
Lenardo, M.J.3
-
11
-
-
0034733584
-
Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations
-
DOI 10.1126/science.288.5475.2354
-
Siegel, R. M., Frederiksen, J. K., Zacharias, D. A., Chan, F. K., Johnson, M., Lynch, D., Tsien, R. Y., and Lenardo, M. J. Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations. Science (Wash. DC), 288: 2354-2357, 2000. (Pubitemid 30448157)
-
(2000)
Science
, vol.288
, Issue.5475
, pp. 2354-2357
-
-
Siegel, R.M.1
Frederiksen, J.K.2
Zacharias, D.A.3
Chan, F.K.-M.4
Johnson, M.5
Lynch, D.6
Tsien, R.Y.7
Lenardo, M.J.8
-
12
-
-
0034733682
-
A domain in TNF receptors that mediates ligand-independent receptor assembty and signaling
-
DOI 10.1126/science.288.5475.2351
-
Chan, F. K., Chun, H. J., Zheng, L., Siegel, R. M., Bui, K. L., and Lenardo, M. J. A domain in TNF receptors that mediates ligand-independent recpetor assembly and signaling. Science (Wash. DC), 288: 2351-2354, 2000. (Pubitemid 30448156)
-
(2000)
Science
, vol.288
, Issue.5475
, pp. 2351-2354
-
-
Chan, F.K.-M.1
Chun, H.J.2
Zheng, L.3
Siegel, R.M.4
Bui, K.L.5
Lenardo, M.J.6
-
13
-
-
0035444539
-
Signal transduction by tumor necrosis factor and its relatives
-
DOI 10.1016/S0962-8924(01)02064-5, PII S0962892401020645
-
Baud, V., and Karin, M. Signal transduction by tumor necrosis factor and its relatives. Trends Cell Biol., 11: 372-377, 2001. (Pubitemid 32900529)
-
(2001)
Trends in Cell Biology
, vol.11
, Issue.9
, pp. 372-377
-
-
Baud, V.1
Karin, M.2
-
14
-
-
0032508414
-
NF-κB anti-apoptosis induction of TRAF-1 and TRAF-2 and c-IAP1 and c-IAP2 to suppress capase-8 activation
-
Wash. DC
-
Wang, C. Y., Mayo, M. W., Korneluk, R. G., Goeddel, D. V., and Baldwin, A. S. J. NF-κB anti-apoptosis induction of TRAF-1 and TRAF-2 and c-IAP1 and c-IAP2 to suppress capase-8 activation. Science (Wash. DC), 281: 1680-1683, 1998.
-
(1998)
Science
, vol.281
, pp. 1680-1683
-
-
Wang, C.Y.1
Mayo, M.W.2
Korneluk, R.G.3
Goeddel, D.V.4
Baldwin, A.S.J.5
-
15
-
-
0033593655
-
Prevention of constitutive TNF receptor 1 signaling by silencer of death domains
-
Wash. DC
-
Jiang, Y., Woronicz, J. D., Liu, W., and Goeddel, D. V. Prevention of constitutive TNF receptor 1 signaling by silencer of death domains. Science (Wash. DC), 283: 543-546, 1999.
-
(1999)
Science
, vol.283
, pp. 543-546
-
-
Jiang, Y.1
Woronicz, J.D.2
Liu, W.3
Goeddel, D.V.4
-
16
-
-
0033521626
-
Mitochondria-dependent and -independent regulation of granzyme B-induced apoptosis
-
MacDonald, G., Shi, L., Vande Velde, C., Lieberman, J., and Greenberg, A. Mitochondria-dependent and -independent regulation of granzyme B-induced apoptosis. J. Exp. Med., 189: 131-144, 1999.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 131-144
-
-
MacDonald, G.1
Shi, L.2
Vande Velde, C.3
Lieberman, J.4
Greenberg, A.5
-
17
-
-
0035897408
-
Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process
-
DOI 10.1083/jcb.153.2.319
-
Waterhouse, N., Goldstein, J., von Ahsen, O., Schuler, M., Newmeyer, D., and Green, D. Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process. J. Cell Biol., 153: 319-328, 2001. (Pubitemid 34280218)
-
(2001)
Journal of Cell Biology
, vol.153
, Issue.2
, pp. 319-328
-
-
Waterhouse, N.J.1
Goldstein, J.C.2
Von Ahsen, O.3
Schuler, M.4
Newmeyer, D.D.5
Green, D.R.6
-
18
-
-
0035235419
-
Breaking the mitochondrial barrier
-
DOI 10.1038/35048069
-
Martinou, J., and Green, D. Breaking the mitochondrial barrier. Nat. Rev. Mol. Cell. Biol., 2: 63-67, 2001. (Pubitemid 33676963)
-
(2001)
Nature Reviews Molecular Cell Biology
, vol.2
, Issue.1
, pp. 63-67
-
-
Martinou, J.-C.1
Green, D.R.2
-
19
-
-
0032575752
-
Mitochondria and apoptosis
-
Green, D. R., and Reed, J. C. Mitochondria and apoptosis. Science (Wash. DC), 281: 1309-1312, 1998. (Pubitemid 28406816)
-
(1998)
Science
, vol.281
, Issue.5381
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
20
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
Gross, A., McDonnell, J. M., and Korsmeyer, S. J. BCL-2 family members and the mitochondria in apoptosis. Genes Dev., 13: 1899-1911, 1999. (Pubitemid 29407357)
-
(1999)
Genes and Development
, vol.13
, Issue.15
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
21
-
-
0030745646
-
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
DOI 10.1016/S0092-8674(00)80501-2
-
Zou, H., Henzel, W., Liu, X., Lutschg, A., and Wang, X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell, 90: 405-413, 1997. (Pubitemid 27347231)
-
(1997)
Cell
, vol.90
, Issue.3
, pp. 405-413
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
22
-
-
0033596980
-
An APAF-1•cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
-
Zou, H., Li, Y., Liu, X., and Wang, X. An APAF-1•cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J. Biol. Chem., 274: 11549-11556, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 11549-11556
-
-
Zou, H.1
Li, Y.2
Liu, X.3
Wang, X.4
-
23
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S., Ahmad, M., Alnemri, E., and Wang, X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell, 91: 479-489, 1997. (Pubitemid 27508237)
-
(1997)
Cell
, vol.91
, Issue.4
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
24
-
-
0032085941
-
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
-
Srinivasula, S. M., Ahmad, M., Fernandes-Alnemri, T., and Alnemri, E. S. Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization. Mol. Cell, 1: 949-957, 1998. (Pubitemid 128379256)
-
(1998)
Molecular Cell
, vol.1
, Issue.7
, pp. 949-957
-
-
Srinivasula, S.M.1
Ahmad, M.2
Fernandes-Alnemri, T.3
Alnemri, E.S.4
-
25
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin, S., Lorenzo, H., Zamzami, N., Marzo, I., Snow, B., Brothers, G., Mangion, J., Jacotot, E., Costantini, P., Loeffler, M., Larochette, N., Goodlett, D., Aebersold, R., Siderovski, D., Penninger, J., and Kroemer, G. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature (Lond.), 397: 441-446, 1999.
-
(1999)
Nature (Lond.)
, vol.397
, pp. 441-446
-
-
Susin, S.1
Lorenzo, H.2
Zamzami, N.3
Marzo, I.4
Snow, B.5
Brothers, G.6
Mangion, J.7
Jacotot, E.8
Costantini, P.9
Loeffler, M.10
Larochette, N.11
Goodlett, D.12
Aebersold, R.13
Siderovski, D.14
Penninger, J.15
Kroemer, G.16
-
26
-
-
0035811496
-
Endonuclease G is an apoptotic DNase when released from mitochondria
-
DOI 10.1038/35083620
-
Li, L., Luo, X., and Wang, X. Endonuclease G is an apoptotic DNase when released from mitochondria. Nature (Lond.), 412: 95-99, 2001. (Pubitemid 32851517)
-
(2001)
Nature
, vol.412
, Issue.6842
, pp. 95-99
-
-
Li, L.Y.1
Luo, X.2
Wang, X.3
-
27
-
-
0034785591
-
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
-
DOI 10.1016/S1097-2765(01)00341-0
-
Suzuki, Y., Imai, Y., Nakayama, H., Takahashi, K., Takio, K., and Takahashi, R. A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Mol. Cell, 8: 613-621, 2001. (Pubitemid 32946938)
-
(2001)
Molecular Cell
, vol.8
, Issue.3
, pp. 613-621
-
-
Suzuki, Y.1
Imai, Y.2
Nakayama, H.3
Takahashi, K.4
Takio, K.5
Takahashi, R.6
-
28
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du, C., Fang, M., Li, Y., Li, L., and Wang, X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell, 102: 33-42, 2000.
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
29
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
Verhagen, A., M., Ekert, P. G., Pakusch, M., Silke, J., Connolly, L. M., Reid, G. E., Moritz, R. L., Simpson, R. J., and Vaux, D. L. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell, 102: 43-53, 2000.
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
Silke, J.4
Connolly, L.M.5
Reid, G.E.6
Moritz, R.L.7
Simpson, R.J.8
Vaux, D.L.9
-
30
-
-
0344959625
-
Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis
-
Xanthoudakis, S., Roy, S., Rasper, D., Hennessey, T., Aubin, Y., Cassady, R., Tawa, P., Ruel, R., Rosen, A., and Nicholson, D. Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis. EMBO J., 18: 2049-2056, 1999. (Pubitemid 29179162)
-
(1999)
EMBO Journal
, vol.18
, Issue.8
, pp. 2049-2056
-
-
Xanthoudakis, S.1
Sophie, R.2
Rasper, D.3
Hennessey, T.4
Aubin, Y.5
Cassady, R.6
Tawa, P.7
Ruel, R.8
Rosen, A.9
Nicholson, D.W.10
-
31
-
-
0033561295
-
Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of Jurkat cells
-
Samali, A., Cai, J., Zhivotovsky, B., Jones, D., and Orrenius, S. Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells. EMBO J., 18: 2040-2048, 1999. (Pubitemid 29179161)
-
(1999)
EMBO Journal
, vol.18
, Issue.8
, pp. 2040-2048
-
-
Samali, A.1
Cai, J.2
Zhivotovsky, B.3
Jones, D.P.4
Orrenius, S.5
-
32
-
-
0032559799
-
The caspase-3 precursor has a cytosolic and mitochondrial distribution: Implications for apoptotic signaling
-
DOI 10.1083/jcb.140.6.1485
-
Mancini, M., Nicholson, D. W., Roy, S., Thornberry, N. A., Peterson, E. P., Casciola-Rosen, L. A., and Rosen, A. The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling. J. Cell Biol., 140: 1485-1495, 1998. (Pubitemid 28152996)
-
(1998)
Journal of Cell Biology
, vol.140
, Issue.6
, pp. 1485-1495
-
-
Mancini, M.1
Nicholson, D.W.2
Roy, S.3
Thornberry, N.A.4
Peterson, E.P.5
Casciola-Rosen, L.A.6
Rosen, A.7
-
33
-
-
0033981577
-
Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane
-
DOI 10.1128/MCB.20.3.929-935.2000
-
Eskes, R., Desagher, S., Antonsson, B., and Martinou, J. Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane. Mol. Cell. Biol., 20: 929-935, 2000. (Pubitemid 30044230)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.3
, pp. 929-935
-
-
Eskes, R.1
Desagher, S.2
Antonsson, B.3
Martinou, J.-C.4
-
34
-
-
0033535350
-
Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis
-
DOI 10.1083/jcb.144.5.891
-
Desagher, S., Osen-Sand, A., Nichols, A., Eskes, R., Montessuit, S., Lauper, S., Maundrell, K., Antonsson, B., and Martinou, J. Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis. J. Cell Biol., 144: 891-901, 1999. (Pubitemid 29238966)
-
(1999)
Journal of Cell Biology
, vol.144
, Issue.5
, pp. 891-901
-
-
Desagher, S.1
Osen-Sand, A.2
Nichols, A.3
Eskes, R.4
Montessuit, S.5
Lauper, S.6
Maundrell, K.7
Antonsson, B.8
Martinou, J.-C.9
-
35
-
-
0034786019
-
L sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
-
L sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Mol. Cell, 8: 705-711, 2001.
-
(2001)
Mol. Cell
, vol.8
, pp. 705-711
-
-
Cheng, E.1
Wei, M.2
Weiler, S.3
Flavell, R.4
Mak, T.5
Lindsten, T.6
Korsmeyer, S.7
-
36
-
-
85047699741
-
L
-
DOI 10.1038/sj/onc/1205270
-
Vieira, H., Boya, P., Cohen, I., El Hamel, C., Haouzi, D., Druillenec, S., Belzacq, A., Brenner, C., Roques, B., and Kroemer, G. Cell permeable BH3-peptides overcome the cytoprotective effect of Bcl-2 and Bcl-XL. Oncogene, 21: 1963-1977, 2002. (Pubitemid 34270885)
-
(2002)
Oncogene
, vol.21
, Issue.13
, pp. 1963-1977
-
-
Vieira, H.L.A.1
Boya, P.2
Cohen, I.3
El, H.C.4
Haouzi, D.5
Druillenec, S.6
Belzacq, A.-S.7
Brenner, C.8
Roques, B.9
Kroemer, G.10
-
37
-
-
0030780106
-
Movement of Bax from the cytosol to mitochondria during apoptosis
-
DOI 10.1083/jcb.139.5.1281
-
Wolter, K., Hsu, Y., Smith, C., Nechushtan, A., Xi, X., and Youle, R. Movement of Bax from the cytosol to mitochondria during apoptosis. J. Cell Biol., 39: 1281-1292, 1997. (Pubitemid 27523214)
-
(1997)
Journal of Cell Biology
, vol.139
, Issue.5
, pp. 1281-1292
-
-
Wolter, K.G.1
Hsu, Y.-T.2
Smith, C.L.3
Nechushtan, A.4
Xi, X.-G.5
Youle, R.J.6
-
38
-
-
9844257587
-
Inhibition of Bax channel-forming activity by Bcl-2
-
DOI 10.1126/science.277.5324.370
-
Antonsson, B., Conti, F., Ciavatta, A., Montessuit, S., Lewis, S., Martinou, I., Bernasconi, L., Bernard, A., Mermod, J., Mazzei, G., Maundrell, K., Gambale, F., Sadoul, R., and Martinou, J. Inhibition of Bax channel-forming activity by Bcl-2. Science (Wash. DC), 277: 370-372, 1997. (Pubitemid 27450709)
-
(1997)
Science
, vol.277
, Issue.5324
, pp. 370-372
-
-
Antonsson, B.1
Conti, F.2
Ciavatta, A.3
Montessuit, S.4
Lewis, S.5
Martinou, I.6
Bernasconi, L.7
Bernard, A.8
Mermod, J.-J.9
Mazzei, G.10
Maundrell, K.11
Gambale, F.12
Sadoul, R.13
Martinou, J.-C.14
-
39
-
-
0032566649
-
Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis
-
DOI 10.1126/science.281.5385.2027
-
Marzo, I., Brenner, C., Zamzami, N., Jurgensmeier, J., Susin, S., Vieira, H. L., Prevost, M., Xie, Z., Matsuyama, S., Reed, J., and Kroemer, G. Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science (Wash. DC), 281: 2027-2031, 1998. (Pubitemid 28475490)
-
(1998)
Science
, vol.281
, Issue.5385
, pp. 2027-2031
-
-
Marzo, I.1
Brenner, C.2
Zamzami, N.3
Jurgensmeier, J.M.4
Susin, S.A.5
Vieira, H.L.A.6
Prevost, M.-C.7
Xie, Z.8
Matsuyama, S.9
Reed, J.C.10
Kroemer, G.11
-
40
-
-
0033519705
-
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
-
DOI 10.1038/20959
-
Shimizu, S., Narita, M., and Tsujimoto, Y. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature (Lond.), 399: 483-487, 1999. (Pubitemid 29258855)
-
(1999)
Nature
, vol.399
, Issue.6735
, pp. 483-487
-
-
Shimizu, S.1
Narita, M.2
Tsujimoto, Y.3
-
41
-
-
0036850312
-
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
-
DOI 10.1016/S0092-8674(02)01036-X
-
Kuwana, T., Mackey, M., Perkins, G., Ellisman, M., Latterich, M., Schneiter, R., Green, D., and Newmeyer, D. Bid, bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane. Cell, 111: 331-342, 2002. (Pubitemid 35341388)
-
(2002)
Cell
, vol.111
, Issue.3
, pp. 331-342
-
-
Kuwana, T.1
Mackey, M.R.2
Perkins, G.3
Ellisman, M.H.4
Latterich, M.5
Schneiter, R.6
Green, D.R.7
Newmeyer, D.D.8
-
42
-
-
0034635952
-
Bax degradation by the ubiquitin/proteasome-dependent pathway: Involvement in tumor survival and progression
-
DOI 10.1073/pnas.070047997
-
Li, B., and Dou, Q. P. Bax degradation by the ubiquitin/proteasome- dependent pathway: involvement in tumor survival and progression. Proc. Natl. Acad. Sci. USA, 97: 3850-3855, 2000. (Pubitemid 30226050)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.8
, pp. 3850-3855
-
-
Li, B.1
Dou, Q.P.2
-
43
-
-
0036323443
-
Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death
-
DOI 10.1083/jcb.200202130
-
Cregan, S., Fortin, A., MacLaurin, J. G., Callaghan, S. M., Cecconi, F., Yu, S. W., Dawson, T. M., Dawson, V. L., Park, D. S., Kroemer, G., and Slack, R. S. Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death. J. Cell Biol., 158: 507-517, 2002. (Pubitemid 34851709)
-
(2002)
Journal of Cell Biology
, vol.158
, Issue.3
, pp. 507-517
-
-
Cregan, S.P.1
Fortin, A.2
MacLaurin, J.G.3
Callaghan, S.M.4
Cecconi, F.5
Yu, S.-W.6
Dawson, T.M.7
Dawson, V.L.8
Park, D.S.9
Kroemer, G.10
Slack, R.S.11
-
44
-
-
0034658350
-
Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2
-
DOI 10.1084/jem.191.10.1709
-
Haraguchi, M., Torii, S., Matsuzawa, S., Xie, Z., Kitada, S., Krajewski, S., Yoshida, H., Mak, T. W., and Reed, J. C. Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2. J. Exp. Med., 191: 1709-1720, 2000. (Pubitemid 30332454)
-
(2000)
Journal of Experimental Medicine
, vol.191
, Issue.10
, pp. 1709-1720
-
-
Haraguchi, M.1
Torii, S.2
Matsuzawa, S.-I.3
Xie, Z.4
Kitada, S.5
Krajewski, S.6
Yoshida, H.7
Mak, T.W.8
Reed, J.C.9
-
45
-
-
0034687754
-
An alternative, nonapoptotic form of programmed cell death
-
DOI 10.1073/pnas.97.26.14376
-
Sperandio, S. I., de Belle, I., and Bredesen, D. E. An alternative, nonapoptotic form of programmed cell death. Proc. Natl. Acad. Sci. USA, 97: 14376-14381, 2000. (Pubitemid 32016583)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.26
, pp. 14376-14381
-
-
Sperandio, S.1
De Belle, I.2
Bredesen, D.E.3
-
46
-
-
0037077254
-
Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway
-
DOI 10.1074/jbc.M202726200
-
Rao, R., Castro-Obregon, S., Frankowski, H., Schuler, M., Stoka, V., del Rio, G., Bredesen, D. E., and Ellerby, H. M. Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway. J. Biol. Chem., 277: 21836-21842, 2002. (Pubitemid 34952336)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.24
, pp. 21836-21842
-
-
Rao, R.V.1
Castro-Obregon, S.2
Frankowski, H.3
Schuler, M.4
Stoka, V.5
Rio, G.D.6
Bredesen, D.E.7
Michael, E.H.8
-
47
-
-
0033082995
-
IAP family proteins - Suppressors of apoptosis
-
Deveraux, Q., and Reed, J. IAP family proteins: suppressors of apoptosis. Genes Dev., 13: 239-252, 1999. (Pubitemid 29095796)
-
(1999)
Genes and Development
, vol.13
, Issue.3
, pp. 239-252
-
-
Deveraux, Q.L.1
Reed, J.C.2
-
48
-
-
0035902601
-
Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death
-
DOI 10.1073/pnas.161506698
-
Suzuki, Y., Nakabayashi, Y., and Takahashi, R. Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death. Proc. Natl. Acad. Sci. USA, 98: 8662-8667, 2001. (Pubitemid 32678084)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.15
, pp. 8662-8667
-
-
Suzuki, Y.1
Nakabayashi, Y.2
Takahashi, R.3
-
49
-
-
0034710649
-
Structural and biochemical basis of apoptotic activation by Smac/DIABLO
-
DOI 10.1038/35022514
-
Chai, J. Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature (Lond.), 406: 855-862, 2000. (Pubitemid 30664254)
-
(2000)
Nature
, vol.406
, Issue.6798
, pp. 855-862
-
-
Chai, J.1
Du, C.2
Wu, J.-W.3
Kyin, S.4
Wang, X.5
Shi, Y.6
-
50
-
-
0034253533
-
Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome
-
Beere, H. M., Wolf, B. B., Cain, K., Kuwana, T., Tailor, P., Morimoto, R. I., Cohen, G., and Green, D. R. Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome. Nat. Cell Biol., 2: 469-475, 2000.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 469-475
-
-
Beere, H.M.1
Wolf, B.B.2
Cain, K.3
Kuwana, T.4
Tailor, P.5
Morimoto, R.I.6
Cohen, G.7
Green, D.R.8
-
51
-
-
0034164455
-
The c-Jun N-terminal kinase pathway and apoptotic signaling
-
Chen, Y. R., and Tan, T. H. The c-Jun N-terminal kinase pathway and apoptotic signaling. Int. J. Oncol., 16: 651-662, 2000.
-
(2000)
Int. J. Oncol.
, vol.16
, pp. 651-662
-
-
Chen, Y.R.1
Tan, T.H.2
-
52
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis, R. J. Signal transduction by the JNK group of MAP kinases. Cell, 103: 239-252, 2000.
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
53
-
-
0032169459
-
JNK targets p53 ubiquitination and degradation in nonstressed cells
-
Fuchs, S. Y., Adler, V., Buschmann, T., Yin, Z., Wu, X., Jones, S. N., and Ronai, Z. JNK targets p53 ubiquitination and degradation in non-stressed cells. Genes Dev., 12: 2658-2663, 1998. (Pubitemid 28420646)
-
(1998)
Genes and Development
, vol.12
, Issue.17
, pp. 2658-2663
-
-
Fuchs, S.Y.1
Adler, V.2
Buschmann, T.3
Yin, Z.4
Wu, X.5
Jones, S.N.6
Ronai, Z.7
-
54
-
-
0032167915
-
MEKK1/JNK signaling stabilizes and activates p53
-
DOI 10.1073/pnas.95.18.10541
-
Fuchs, S. Y., Adler, V., Pincus, M. R., and Ronai, Z. MEKK1/JNK signaling stabilizes and activates p53. Proc. Natl. Acad. Sci. USA, 95: 10541-10546, 1998. (Pubitemid 28413103)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.18
, pp. 10541-10546
-
-
Fuchs, S.Y.1
Adler, V.2
Pincus, M.R.3
Ronai, Z.4
-
55
-
-
0032703216
-
Regulation of c-Myc through phosphorylation at Ser-62 and Ser-71 by c-Jun N-terminal kinase
-
Noguchi, K., Kitanaka, C., Tamana, H., Kokubu, A., Mochizuki, T., and Kuchino, Y. Regulation of c-Myc through phosphorylation at Ser-62 and Ser-71 by c-Jun N-terminal kinase. J. Biol. Chem., 274: 32580-32587, 1999. (Pubitemid 129535283)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.46
, pp. 32580-32587
-
-
Noguchi, K.1
Kitanaka, C.2
Yamana, H.3
Kokubu, A.4
Mochizuki, T.5
Kuchino, Y.6
-
56
-
-
0033499801
-
2/M
-
Yamamoto, K., Ichijo, H., and Korsmeyer, S. J. BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G2/M. Mol. Cell. Biol., 19: 8469-8478, 1999. (Pubitemid 30414041)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.12
, pp. 8469-8478
-
-
Yamamoto, K.1
Ichijo, H.2
Korsmeyer, S.J.3
-
57
-
-
0034607702
-
Requirement of JNK for stress-induced activation of the cytochrome c- mediated death pathway
-
DOI 10.1126/science.288.5467.870
-
Tournier, C., Hess, P., Yang, D. D., Xu, J., Turner, T. K., Nimnual, A., Bar-Sagi, D., Jones, S. N., Flavell, R. A., and Davis, R. J. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science (Wash. DC), 288: 870-874, 2000. (Pubitemid 30257738)
-
(2000)
Science
, vol.288
, Issue.5467
, pp. 870-874
-
-
Tournier, C.1
Hess, P.2
Yang, D.D.3
Xu, J.4
Turner, T.K.5
Nimnual, A.6
Bar-Sagi, D.7
Jones, S.N.8
Flavell, R.A.9
Davis, R.J.10
-
58
-
-
0032752063
-
Cellular survival: A play in three Akts
-
Datta, S. D., Brunet, A., and Greenberg, M. Cellular survival: a play in three Akts. Genes Dev., 13: 2905-2927, 1999.
-
(1999)
Genes Dev.
, vol.13
, pp. 2905-2927
-
-
Datta, S.D.1
Brunet, A.2
Greenberg, M.3
-
59
-
-
0030584088
-
Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
-
DOI 10.1016/S0092-8674(00)81382-3
-
Zha, J., Harada, E., Yang, J., Jockel, J., and Korsmeyer, S. J. Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-XL. Cell, 87: 619-628, 1996. (Pubitemid 26386936)
-
(1996)
Cell
, vol.87
, Issue.4
, pp. 619-628
-
-
Zha, J.1
Harada, H.2
Yang, E.3
Jockel, J.4
Korsmeyer, S.J.5
-
60
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor
-
Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., Anderson, M. J., Arden, K. C., Blenis, J., and Greenberg, M. E. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell, 96: 857-868, 1999. (Pubitemid 29165088)
-
(1999)
Cell
, vol.96
, Issue.6
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
Anderson, M.J.7
Arden, K.C.8
Blenis, J.9
Greenberg, M.E.10
-
61
-
-
0034609737
-
Expression of the pro-apoptotic family member Bim is regulated by the Forkhead transcription factor, FKMR-L1
-
Dikers, P. F., Medema, J-H., Lammes, J., Koenderman, L., and Coffer, P. J. Expression of the pro-apoptotic family member Bim is regulated by the Forkhead transcription factor, FKMR-L1. Curr. Biol., 10: 1201-1204, 2000.
-
(2000)
Curr. Biol.
, vol.10
, pp. 1201-1204
-
-
Dikers, P.F.1
Medema, J.-H.2
Lammes, J.3
Koenderman, L.4
Coffer, P.J.5
-
62
-
-
0033519453
-
Induction of NF-κB by the Akt/PKB kinase
-
Kane, L. P., Shapiro, V. S., Stokoe, D., and Weiss, A. Induction of NF-κB by the Akt/PKB kinase. Curr. Biol., 9: 601-604, 1999.
-
(1999)
Curr. Biol.
, vol.9
, pp. 601-604
-
-
Kane, L.P.1
Shapiro, V.S.2
Stokoe, D.3
Weiss, A.4
-
63
-
-
0033558215
-
The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosis
-
Zong, W-X., Edelstein, L. C., Chen, C., Bash, J., and Gelinas, C. The pro-survival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNF-α-induced apoptosis. Genes Dev., 13: 382-387, 1999. (Pubitemid 29108753)
-
(1999)
Genes and Development
, vol.13
, Issue.4
, pp. 382-387
-
-
Zong, W.-X.1
Edelstein, L.C.2
Chen, C.3
Bash, J.4
Gelinas, C.5
-
64
-
-
0030707537
-
ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein
-
You, M., Ku, P. T., Hirdlickova, R., and Bose, H. R. J. ch-IAP1, a member of the the inhibitor-of-apoptosis protein family, is a mediater of the antiapoptotic activity of the v-Rel oncoprotein. Mol. Cell. Biol., 17: 7328-7341, 1997. (Pubitemid 27505962)
-
(1997)
Molecular and Cellular Biology
, vol.17
, Issue.12
, pp. 7328-7341
-
-
You, M.1
Ku, P.-T.2
Hrdlickova, R.3
Bose Jr., H.R.4
-
65
-
-
0033596124
-
Aberrant rel/nfkb genes and activity in human cancer
-
Rayet, B., and Gelinas, C. Aberrant rel/nfkb genes and activity in human cancer. Oncogene, 18: 6938-6947, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 6938-6947
-
-
Rayet, B.1
Gelinas, C.2
-
66
-
-
0033551387
-
Mechanisms of apoptosis by c-Myc
-
DOI 10.1038/sj.onc.1202727
-
Prendergast, G. Mechanisms of apoptosis by c-Myc. Oncogene, 18: 2967-2987, 1999. (Pubitemid 29276537)
-
(1999)
Oncogene
, vol.18
, Issue.19
, pp. 2967-2987
-
-
Prendergast, G.C.1
-
67
-
-
0034609762
-
A "non-canonical" DNA-binding element mediates the response of the Fas-ligand promoter to c-Myc
-
Kasibhatla, S., Beere, H., Brunner, T., Echeverri, F., and Green, D. A "non-canonical" DNA-binding element mediates the response of the Fas-ligand promoter to c-Myc. Curr. Biol., 10: 1205-1208, 2000.
-
(2000)
Curr. Biol.
, vol.10
, pp. 1205-1208
-
-
Kasibhatla, S.1
Beere, H.2
Brunner, T.3
Echeverri, F.4
Green, D.5
-
68
-
-
0033993563
-
The ARF/p53 pathway
-
DOI 10.1016/S0959-437X(99)00038-6
-
Sher, C. J., and Weber, J. D. The ARF/p53 pathway. Curr. Opin. Genet. Dev., 10: 94-99, 2000. (Pubitemid 30113711)
-
(2000)
Current Opinion in Genetics and Development
, vol.10
, Issue.1
, pp. 94-99
-
-
Sherr, C.J.1
Weber, J.D.2
-
69
-
-
0034737732
-
Expression of Fas ligand in activated T cells is regulated by c-Myc
-
DOI 10.1074/jbc.275.13.9767
-
Brunner, T., Kasibhatla, S., Pinkoski, M., Frutschi, C., Yoo, N., Echeverri, F., Mahboubi, A., and Green, D. Expression of Fas ligand in activated T cells is regulated by c-Myc. J. Biol. Chem., 275: 9767-9772, 2000. (Pubitemid 30185211)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.13
, pp. 9767-9772
-
-
Brunner, T.1
Kasibhatla, S.2
Pinkoski, M.J.3
Frutschi, C.4
Yoo, N.J.5
Echeverri, F.6
Mahboubi, A.7
Green, D.R.8
-
70
-
-
0033152390
-
c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release
-
Juin, P., Hueber, A. O., Littlewood, T., and Evan, G. c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release. Genes Dev., 13: 1367-1381, 1999. (Pubitemid 29270243)
-
(1999)
Genes and Development
, vol.13
, Issue.11
, pp. 1367-1381
-
-
Juin, P.1
Hueber, A.-O.2
Littlewood, T.3
Evan, G.4
-
71
-
-
0036333713
-
c-Myc functionally cooperates with Bax to induce apoptosis
-
DOI 10.1128/MCB.22.17.6158-6169.2002
-
Juin, P., Hunt, A., Littlewood, T., Griffiths, B., Swigart, L., Korsmeyer, S., and Evan, G. c-Myc functionally cooperates with Bax to induce apoptosis, Mol. Cell. Biol., 22: 6158-6169, 2002. (Pubitemid 34857836)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.17
, pp. 6158-6169
-
-
Juin, P.1
Hunt, A.2
Littlewood, T.3
Griffiths, B.4
Swigart, L.B.5
Korsmeyer, S.6
Evan, G.7
-
72
-
-
0036561484
-
p53 leans on its siblings
-
DOI 10.1016/S1535-6108(02)00064-8
-
Urist, M., and Prives, C. p53 leans on its siblings. Cancer Cell, 1: 311-313, 2002. (Pubitemid 41039132)
-
(2002)
Cancer Cell
, vol.1
, Issue.4
, pp. 311-313
-
-
Urist, M.1
Prives, C.2
-
73
-
-
0036674617
-
Live or let die: The cell's response to p53
-
DOI 10.1038/nrc864
-
Vousden, K., and Lu, X. Live or let die: the cell's response to p53. Nat. Rev. Cancer, 2: 594-604, 2002. (Pubitemid 37328926)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.8
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
74
-
-
0035370483
-
Regulation and function of the p53 tumor suppressor protein
-
DOI 10.1016/S0955-0674(00)00216-7
-
Ryan, K., Phillips, A., and Vousden, K. Regulation and function of the p53 tumor suppressor protein. Curr. Opin. Cell Biol., 13: 332-337, 2001. (Pubitemid 32429498)
-
(2001)
Current Opinion in Cell Biology
, vol.13
, Issue.3
, pp. 332-337
-
-
Ryan, K.M.1
Phillips, A.C.2
Vousden, K.H.3
-
75
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
DOI 10.1126/science.288.5468.1053
-
Oda, E., Ohki, R., Murasawa, H., Nemoto, J., Shibue, T., Yamashita, T., Tokino, T., Taniguchi, T., and Tanaka, N. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science (Wash. DC), 288: 1053-1058, 2000. (Pubitemid 30324238)
-
(2000)
Science
, vol.288
, Issue.5468
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
76
-
-
0034664733
-
p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53
-
Oda, K., Arakawa, H., Tanaka, T., Matsuda, K., Tanikawa, C., Mori, T., Nishimori, H., Tamai, K., Tokino, T., Nakamura, Y., and Taya, Y. p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell, 102: 849-862, 2000.
-
(2000)
Cell
, vol.102
, pp. 849-862
-
-
Oda, K.1
Arakawa, H.2
Tanaka, T.3
Matsuda, K.4
Tanikawa, C.5
Mori, T.6
Nishimori, H.7
Tamai, K.8
Tokino, T.9
Nakamura, Y.10
Taya, Y.11
-
77
-
-
0033812557
-
Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis
-
Lin, Y., Ma, W., and Benchimol, S. Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis. Nat. Genet., 26: 122-127, 2000.
-
(2000)
Nat. Genet.
, vol.26
, pp. 122-127
-
-
Lin, Y.1
Ma, W.2
Benchimol, S.3
-
78
-
-
0033053944
-
p53-oriented cancer therapies: Current progress
-
DOI 10.1023/A:1008368500557
-
Gallagher, W. M., and Brown, R. p53-orientated cancer therapies: current progress. Ann. Oncol., 10: 139-150, 1999. (Pubitemid 29113172)
-
(1999)
Annals of Oncology
, vol.10
, Issue.2
, pp. 139-150
-
-
Gallagher, W.M.1
Brown, R.2
-
79
-
-
0030961889
-
Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain
-
DOI 10.1038/nm0697-632
-
Selivanova, G., Iotsova, V., and Okan, I. Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain. Nat. Med., 3: 632-638, 1997. (Pubitemid 27264972)
-
(1997)
Nature Medicine
, vol.3
, Issue.6
, pp. 632-638
-
-
Selivanova, G.1
Iotsova, V.2
Okan, I.3
Fritsche, M.4
Strom, M.5
Groner, B.6
Grafstrom, R.C.7
Wiman, K.G.8
-
80
-
-
0029124132
-
Microinjection of monoclonal antibody PAb421 into human SW480 colorectal carcinoma cells restores the transcription activation function to mutant p53
-
Abarzua, P., Lsardo, J. E., and Gubler, M. L. Microinjection of monoclonal antibody PAb421 into human SW480 colorectal carcinoma cells restores the transcription activation function to mutant p53. Cancer Res., 55: 3490-3494, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 3490-3494
-
-
Abarzua, P.1
Lsardo, J.E.2
Gubler, M.L.3
-
81
-
-
0033601370
-
Pharmacological rescue of mutant p53 confomation and function
-
Wash. DC
-
Foster, B. Pharmacological rescue of mutant p53 confomation and function. Science (Wash. DC), 286: 2507-2510, 1999.
-
(1999)
Science
, vol.286
, pp. 2507-2510
-
-
Foster, B.1
-
82
-
-
0031282325
-
Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo
-
Bottger, A., Bottger, V., and Sparks, A. Design of a synthetic Mdm-2-binding mini protein that activates the p53 response in vivo. Curr. Biol., 7: 860-869, 1997. (Pubitemid 27493125)
-
(1997)
Current Biology
, vol.7
, Issue.11
, pp. 860-869
-
-
Bottger, A.1
Bottger, V.2
Sparks, A.3
Liu, W.-L.4
Howard, S.F.5
Lane, D.P.6
-
83
-
-
0036710477
-
Prospects for targeting the Bcl-2 family of proteins to develop novel cytotoxic drugs
-
DOI 10.1016/S0006-2952(02)01148-6, PII S0006295202011486
-
Baell, J., and Huang, D. Prospects for targeting the Bcl-2 family of proteins to develop novel cytotoxic drugs. Biochem. Pharmacol., 64: 851-863, 2002. (Pubitemid 35232259)
-
(2002)
Biochemical Pharmacology
, vol.64
, Issue.5-6
, pp. 851-863
-
-
Baell, J.B.1
Huang, D.C.S.2
-
84
-
-
0030888664
-
BCL-2 antisense therapy in patients with non-Hodgkin lymphoma
-
DOI 10.1016/S0140-6736(96)11103-X
-
Webb, A., Cunningham, D., Cotter, F., Clarke, P., DdiStefano, F., Ross, P., Corbo, M., and Dziewanowska, Z. Bcl-2 antisense therapy in patients with non-Hodgkin lymphoma. Lancet, 349: 1137-1141, 1997. (Pubitemid 27168548)
-
(1997)
Lancet
, vol.349
, Issue.9059
, pp. 1137-1141
-
-
Webb, A.1
Cunningham, D.2
Cotter, F.3
Clarke, P.A.4
Di, S.F.5
Ross, P.6
Corbo, M.7
Dziewanowska, Z.8
-
85
-
-
0031907428
-
bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice
-
DOI 10.1038/nm0298-232
-
Jansen, B., Schlagbauer-Wadl, H., Brown, B., Bryan, R., van Elsas, A., Muller, M., Wolff, K., Eichler, H., and Pehamberger, H. bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice. Nat. Med., 4: 232-234, 1998. (Pubitemid 28137379)
-
(1998)
Nature Medicine
, vol.4
, Issue.2
, pp. 232-234
-
-
Jansen, B.1
Schlagbauer-Wadl, H.2
Brown, B.D.3
Bryan, R.N.4
Van Elsas, A.5
Muller, M.6
Wolff, K.7
Eichler, H.-G.8
Pehamberger, H.9
-
86
-
-
0032523945
-
Modulation of Bcl-2 protein levels by an intracellular anti-Bcl-2 single-chain antibody increases drug-induced cytotoxicity in the breast cancer cell line MCF-7
-
Piche, A., Grim, J., Rancourt, C., Gomez-Navarro, J., Reed, J. C., and Curiel, D. T. Modulation of Bcl-2 protein levels by an intracellular anti-Bcl-2 single-chain antibody increases drug-induced cytotoxicity in the breast cancer cell line MCF-7. Cancer Res., 58: 2134-2140, 1998. (Pubitemid 28232899)
-
(1998)
Cancer Research
, vol.58
, Issue.10
, pp. 2134-2140
-
-
Piche, A.1
Grim, J.2
Rancourt, C.3
Gomez-Navarro, J.4
Reed, J.C.5
Curiel, D.T.6
-
87
-
-
0035150803
-
L
-
DOI 10.1038/35055085
-
Degterev, A. Identification of small molecule inhibitors of interaction between the BH3 domain and BCL-XL. Nat. Cell Biol., 3: 173-182, 2001. (Pubitemid 32118371)
-
(2001)
Nature Cell Biology
, vol.3
, Issue.2
, pp. 173-182
-
-
Degterev, A.1
Lugovskoy, A.2
Cardone, M.3
Mulley, B.4
Wagner, G.5
Mitchison, T.6
Yuan, J.7
-
88
-
-
0034722884
-
Bcl-2 family proteins as targets for anticancer drug design
-
Huang, Z. Bcl-2 family proteins as targets for anticancer drug design. Oncogene, 19: 6627-6631, 1999.
-
(1999)
Oncogene
, vol.19
, pp. 6627-6631
-
-
Huang, Z.1
-
89
-
-
0035147650
-
Antimycin A mimics a cell death-inducing Bcl-2 homology domain 3
-
Tzung, S. Antimycin A mimics a cell death-inducing Bcl-2 homology domain 3. Nat. Cell Biol., 3: 183-192, 2001.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 183-192
-
-
Tzung, S.1
-
90
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker, B., Tamura, S., Buchdunger, E., Ohno, S., Segal, G., Fanning, S., Zimmermann, J., and Lydon, N. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat. Med., 2: 561-566, 1996.
-
(1996)
Nat. Med.
, vol.2
, pp. 561-566
-
-
Druker, B.1
Tamura, S.2
Buchdunger, E.3
Ohno, S.4
Segal, G.5
Fanning, S.6
Zimmermann, J.7
Lydon, N.8
-
91
-
-
0034254368
-
Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: Diverse mechanisms of resistance
-
Mahon, F., Deininger, M., Schultheis, B., Chabrol, J., Reiffers, J., Goldman, J., and Melo, J. Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: diverse mechanisms of resistance. Blood, 96: 1070-1079, 2000. (Pubitemid 30616875)
-
(2000)
Blood
, vol.96
, Issue.3
, pp. 1070-1079
-
-
Mahon, F.X.1
Deininger, M.W.N.2
Schultheis, B.3
Chabrol, J.4
Reiffers, J.5
Goldman, J.M.6
Melo, J.V.7
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