Role of oxidative stress in myocardial hypertrophy and failure

Journal of Molecular and Cellular Cardiology

Volumn 34, Issue 4, 2002, Pages 379-388

  Sawyer, Douglas B ^a   Siwik, Deborah A ^a   Xiao, Lei ^a   Pimentel, David R ^a   Singh, Krishna ^a   Colucci, Wilson S ^a  

^a BOSTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Myocardial remodeling; Oxidative stress; Superoxide; Superoxide dismutase

Indexed keywords

ANTIOXIDANT; MATRIX PROTEIN; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; XANTHINE OXIDASE; MITOGEN ACTIVATED PROTEIN KINASE;

APOPTOSIS; CELL DEATH; CELL FUNCTION; CELL PROTECTION; CELL STRUCTURE; COLLAGEN SYNTHESIS; FIBROBLAST; GENE EXPRESSION; HEART FAILURE; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE; HEART VENTRICLE HYPERTROPHY; HUMAN; MITOCHONDRION; MUSCLE CELL; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; REVIEW; ANIMAL; CARDIOMEGALY; CONGESTIVE HEART FAILURE; HEART; METABOLISM; PHYSIOLOGY;

ANIMALIA;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CARDIOMEGALY; CELL DEATH; FIBROBLASTS; HEART; HEART FAILURE, CONGESTIVE; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE FIBERS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 0036545584     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2002.1526     Document Type: Review

References (74)

1. Cohn J.N. Structural changes in cardiovascular disease. Am J Cardiol. 76:1995;34E-37E.
2. Gerdes A.M., Liu Z., Zimmer H.G. Changes in nuclear size of cardiac myocytes during the development and progression of hypertrophy in rats. Cardioscience. 5:1994;203-208.
3. MacLellan W.R., Schneider M.D. Death by Design. Programmed cell death in cardiovascular biology and disease. Circ Res. 81:1997;137-144.
4. Olivetti G., Capasso J.M., Sonnenblick E.H., Anversa P. Side-to-side slippage of myocytes participates in ventricular wall remodeling acutely after myocardial infarction in rats. Circ Res. 67:1990;23-34.
5. Weber K.T., Anversa P., Armstrong P.W., Brilla C.G., Burnett JC Jr, Cruickshank J.M., Devereux R.B., Giles T.D., Korsgaard N., Leier C.V. Remodeling and reparation of the cardiovascular system. J Am Coll Cardiol. 20:1992;3-16.
6. Mann D.L., Spinale F.G. Activation of matrix metalloproteinases in the failing human heart: breaking the tie that binds. Circulation. 98:1998;1699-1702.
7. + exchange in the infarcted heart. Implications for excitation-contraction coupling. Circ Res. 81(6):1997;1083-1093.
8. Morgan J.P., Erny R.E., Allen P.D., Grossman W., Gwathmey J.K. Abnormal intracellular calcium handling, a major cause of systolic and diastolic dysfunction in ventricular myocardium from patients with heart failure. Circulation. 81 (Suppl. 2):1990;III21-III32.
9. Dhalla N.S., Temsah R.M., Netticadan T. Role of oxidative stress in cardiovascular diseases. J Hypertens. 18:2000;655-673.
10. Halliwell B., Gutteridge J.M.C. Free Radicals in Biology and Medicine. London, Great Britain: Oxford University Press. 1989.
11. Assem M., Teyssier J.R., Benderitter M., Terrand J., Laubriet A., Javouhey A., David M., Rochette L. Pattern of superoxide dismutase enzymatic activity and RNA changes in rat heart ventricles after myocardial infarction. Am J Pathol. 151:1997;549-555.
12. Li Y., Huang T-T, Carlson E.J., Melov S., Ursell P.C., Olson J.L., Noble L.J., Yoshimura M.P., Berger C., Chan P.H., Wallace D.C., Epstein C.J. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nature Genetics. 11:1995;376-381.
13. Yoshida T., Maulik N., Engelman R.M., Ho Y.S., Das D.K. Targeted disruption of the mouse Sod I gene makes the hearts vulnerable to ischemic reperfusion injury. Circ Res. 86:2000;264-269.
14. Carlsson L.M., Jonsson J., Edlund T., Marklund S.L. Mice lacking extracellular superoxide dismutase are more sensitive to hyperoxia. Proc Natl Acad Sci USA. 92:1995;6264-6268.
15. Pandolfi P.P., Sonati F., Rivi R., Mason P., Grosveld F., Luzzatto L. Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress. EMBO J. 14:1995;5209-5215.
16. Martini G., Ursini M.V. A new lease of life for an old enzyme. Bioessays. 18:1996;631-637.
17. Ghatak A., Brar M.J., Agarwal A., Goel N., Rastogi A.K., Vaish A.K., Sircar A.R., Chandra M. Oxy free radical system in heart failure and therapeutic role of oral vitamin E. Int J Cardiol. 57(2):1996;119-127.
18. Diaz-Velez C.R., Garcia-Castineiras S., Mendoza-Ramos E., Hernandez-Lopez E. Increased malondialdehyde in peripheral blood of patients with congestive heart failure. Am Heart J. 131(1):1996;146-152.
19. Keith M., Geranmayegan A., Sole M.J., Kurian R., Robinson A., Omran A.S., Jeejeebhoy K.N. Increased oxidative stress in patients with congestive heart failure. J Am Coll Cardiol. 31:1998;1352-1356.
20. Mallat Z., Philip I., Lebret M., Chatel D., Maclouf J., Tedgui A. Elevated levels of 8-iso-prostaglandin F2alpha in pericardial fluid of patients with heart failure: a potential role for in vivo oxidant stress in ventricular dilatation and progression to heart failure. Circulation. 97:1998;1536-1539.
21. Hill M.F., Singal P.K. Antioxidant and oxidative stress changes during heart failure subsequent to myocardial infarction in rats. Am J Pathol. 148:1996;291-300.
22. Dhalla A.K., Hill M.F., Singal P.K. Role of oxidative stress in transition of hypertrophy to heart failure. J Am Coll Cardiol. 28:1996;506-514.
23. Ide T., Tsutsui H., Kinugawa S., Utsumi H., Kang D., Hattori N., Uchida K., Arimura K., Egashira K., Takeshita A. Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium. Circ Res. 85:1999;357-363.
24. Singal P.K., Kapur N., Dhillon K.S., Beamish R.E., Dhalla N.S. Role of free radicals in catecholamine-induced cardiomyopathy. Can J Physiol Pharmacol. 60:1982;1390-1397.
25. Singal P.K., Dhalla A.K., Hill M., Thomas T.P. Endogenous antioxidant changes in the myocardium in response to acute and chronic stress conditions. Mol Cell Biochem. 129:1993;179-186.
26. Dhalla A.K., Singal P.K. Antioxidant changes in hypertrophied and failing guinea pig hearts. Am J Physiol. 266:1994;H1280-H1285.
27. Baumer A.T., Flesch M., Wang X., Shen Q., Feuerstein G.Z., Bohm M. Antioxidative enzymes in human hearts with idiopathic dilated cardiomyopathy. J Mol Cell Cardiol. 32:2000;121-130.
28. Dieterich S., Bieligk U., Beulich K., Hasenfuss G., Prestle J. Gene expression of antioxidative enzymes in the human heart: increased expression of catalase in the end-stage failing heart. Circulation. 101:2000;33-39.
29. Sam F., Kerstetter D.L., Pimentel D.R., Muluktla S., Tabaee A., Ngo K., Pligavko C.A., Bristow M.R., Colucci W.S., Sawyer D.B. Decreased activity of manganese superoxide dismutase (MnSOD) in failing human myocardium. Circulation. 102:2000;II-84.
30. Kinugawa S., Tsutsui H., Hayashidani S., Ide T., Suematsu N., Satoh S., Utsumi H., Takeshita A. Treat- ment with dimethylthiourea prevents left ventricular remodeling and failure after experimental myocardial infarction in mice: role of oxidative stress. Circ Res. 87:2000;392-398.
31. Ide T., Tsutsui H., Kinugawa S., Suematsu N., Hayashidani S., Ichikawa K., Utsumi H., Machida Y., Egashira K., Takeshita A. Direct evidence for increased hydroxyl radicals originating from superoxide in the failing myocardium. Circ Res. 86:2000;152-157.
32. Opie L.H., Thandroyen F.T., Muller C., Bricknell O.L. Adrenaline-induced "oxygen-wastage" and enzyme release from working rat heart. Effects of calcium antagonism, beta-blockade, nicotinic acid and coronary artery ligation. J Mol Cell Cardiol. 11:1979;1073-1094.
33. Griendling K.K., Minieri C.A., Ollerenshaw J.D., Alexander R.W. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res. 74:1994;1141-1148.
34. Ekelund U.E., Harrison R.W., Shokek O., Thakkar R.N., Tunin R.S., Senzaki H., Kass D.A., Marban E., Hare J.M. Intravenous allopurinol decreases myocardial oxygen consumption and increases mechanical efficiency in dogs with pacing-induced heart failure. Circ Res. 85:1999;437-445.
35. + calmodulin-dependent and tetrahydrobiopterin regulatory process. J Biol Chem. 273:1998;25804-25808.
36. Griendling K.K., Ushio-Fukai M. Redox control of vascular smooth muscle proliferation. J Lab Clin Med. 132:1998;9-15.
37. Babior B.M. Activation of the respiratory burst oxidase. Environ Health Perspect. 102 (Suppl. 10):1994;53-56.
38. Griendling K.K., Sorescu D., Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res. 86:2000;494-501.
39. Xiao L., Pimentel D.R., Wang J., Singh K., Colucci W.S., Sawyer D.B. Reactive oxygen species mediate alpha1-adrenergic receptor-stimulated hypertrophic signaling in cardiac myocytes: role of NAD(P)H oxidase. Am J Physiol. 2002.
40. Haywood G.A., Tsao P.S., von der Leyen H.E., Mann M.J., Keeling P.J., Trindade P.T., Lewis N.P., Byrne C.D., Rickenbacher P.R., Bishopric N.H., Cooke J.P., McKenna W.J., Fowler M.B. Expression of inducible nitric oxide synthase in human heart failure. Circulation. 93:1996;1087-1094.
41. Habib F.M., Springall D.R., Davies G.J., Oakley C.M., Yacoub M.H., Polak J.M. Tumour necrosis factor and inducible nitric oxide synthase in dilated cardiomyopathy. Lancet. 347:1996;1151-1155.
42. Xia Y., Zweier J.L. Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages. Proc Natl Acad Sci USA. 94:1999;6954-6958.
43. Siwik D.A., Tzortzis J.D., Pimental D.R., Chang D.L., Pagano P.J., Singh K., Sawyer D.B., Colucci W.S. Inhibition of copper-zinc superoxide dismutase induces cell growth, hypertrophic phenotype, and apoptosis in neonatal rat cardiac myocytes in vitro. Circ Res. 85:1999;147-153.
44. Sadoshima J., Xu Y., Slayter H.S., Izumo S. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac muscles in vitro. Cell. 75:1993;977-984.
45. Cheng W., Li B., Kajstura J., Li P., Wolin M.S., Sonnenblick E.H., Hintze T.H., Olivetti G., Anversa P. Stretch-induced programmed myocyte cell death. J Clin Invest. 96:1995;2247-2259.
46. Leri A., Claudio P.P., Li Q., Wang X., Reiss K., Wang S., Malhotra A., Kajstura J., Anversa P. Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell. J Clin Invest. 101:1998;1326-1342.
47. Pimentel D.R., Amin J.K., Xiao L., Miller T., Viereck J., Oliver-Krasinski J., Baliga R.R., Wang J., Siwik D.A., Singh K., Pagano P.J., Colucci W.S., Sawyer D.B. Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes. Circ Res. 89:2001;453-460.
48. Nakamura K., Fushimi K., Kouchi H., Mihara K., Miyazaki M., Ohe T., Namba M. Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-alpha and angiotensin II. Circulation. 98:1998;794-799.
49. Amin J.K., Xiao L., Pimentel D.R., Pagano P.J., Singh K., Sawyer D.B., Colucci W.S. Reactive oxygen species mediate alpha-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes. J Mol Cell Cardiol. 33:2001;131-139.
50. Cheng T.H., Shih N.L., Chen S.Y., Wang D.L., Chen J.J. Reactive oxygen species modulate endothelin-I-induced c-fos gene expression in cardiomyocytes. Cardiovasc Res. 41:1999;654-662.
51. Kometiani P., Li J., Gnudi L., Kahn B.B., Askari A., Xie Z. Multiple signal transduction pathways link Na+/K+-ATPase to growth-related genes in cardiac myocytes. The roles of Ras and mitogen-activated protein kinases. J Biol Chem. 273:1998;15249-15256.
52. Tanaka K., Honda M., Takabatake T. Redox regulation of MAPK pathways and cardiac hypertrophy in adult rat cardiac myocyte. J Am Coll Cardiol. 37:2001;676-685.
53. Ushio-Fukai M., Zafari A.M., Fukui T., Ishizaka N., Griendling K.K. p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells. J Biol Chem. 271:1996;23317-23321.
54. Weber K.T., Sun Y., Katwa L.C., Cleutjens J.P., Zhou G. Connective tissue and repair in the heart. Potential regulatory mechanisms. Ann NY Acad Sci. 752:1995;286-299.
55. Spinale F.G., Coker M.L., Bond B.R., Zellner J.L. Myocardial matrix degradation and metalloproteinase activation in the failing heart: a potential therapeutic target. Cardiovasc Res. 46:2000;225-238.
56. Siwik D.A., Pagano P.J., Colucci W.S. Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts. Am J Physiol Cell Physiol. 280:2001;C53-C60.
57. Taimor G., Lorenz H., Hofstaetter B., Schluter K.D., Piper H.M. Induction of necrosis but not apoptosis after anoxia and reoxygenation in isolated adult cardiomyocytes of rat. Cardiovasc Res. 41:1999;147-156.
58. Saikumar P., Dong Z., Weinberg J.M., Venkatachalam M.A. Mechanisms of cell death in hypoxia/reoxygenation injury. Oncogene. 17:1998;3341-3349.
59. von Harsdorf R., Li P.F., Dietz R. Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis. Circulation. 99:1999;2934-2941.
60. Pinsky D.J., Cai B., Yang X., Rodriguez C., Sciacca R.R., Cannon P.J. The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor β J Clin Invest. 95:1995;677-685.
61. Ing D.J., Zang J., Dzau V.J., Webster K.A., Bishopric N.H. Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bak, and Bcl-x. Circ Res. 84:1999;21-33.
62. Arstall M.A., Sawyer D.B., Fukazawa R., Kelly R.A. Cytokine-mediated apoptosis in cardiac myocytes: the role of inducible nitric oxide synthase induction and peroxynitrite generation. Circ Res. 85:1999;829-840.
63. Sam F., Sawyer D.B., Xie Z., Chang D.L., Ngoy S., Brenner D.A., Siwik D.A., Singh K., Apstein C.S., Colucci W.S. Mice lacking inducible nitric oxide synthase have improved left ventricular contractile function and reduced apoptotic cell death late after myocardial infarction. Circ Res. 89:2001;351-356.
64. Communal C., Singh K., Pimentel D.R., Colucci W.S. Norepinephrine stimulates apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway. Circulation. 98:1998;1329-1334.
65. Zaugg M., Xu W., Lucchinetti E., Shafiq S.A., Jamali N.Z., Siddiqui M.A. Beta-adrenergic receptor subtypes differentially affect apoptosis in adult rat ventricular myocytes. Circulation. 102:2000;344-350.
66. Communal C., Singh K., Sawyer D.B., Colucci W.S. Opposing effects of beta(1)- and beta(2)-adrenergic receptors on cardiac myocyte apoptosis: role of a pertussis toxin-sensitive G protein. Circulation. 100:1999;2210-2212.
67. Communal C., Xie X., Sawyer D.B., Singh K., Colucci W.S. Beta-adrenergic receptor-stimulated apoptosis involves mitochondrial pathways and reactive oxygen species. Circulation. 102:2000;II-9.
68. Cai J., Jones D.P. Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss. J Biol Chem. 273:1998;11401-11404.
69. Zhu W.Z., Zheng M., Koch W.J., Lefkowitz R.J., Kobilka B.K., Xiao R.P. Dual modulation of cell survival and cell death by beta(2)-adrenergic signaling in adult mouse cardiac myocytes. Proc Natl Acad Sci USA. 98:2001;1607-1612.
70. Kukin M.L., Kalman J., Charney R.H., Levy D.K., Buchholz-Varley C., Ocampo O.N., Eng C. Prospective, randomized comparison of effect of long-term treatment with metoprolol or carvedilol on symptoms, exercise, ejection fraction, and oxidative stress in heart failure. Circulation. 99:1999;2645-2651.
71. Ruffolo RR Jr, Feuerstein G.Z. Carvedilol: preclinical profile and mechanisms of action in preventing the progression of congestive heart failure. Eur Heart J. 19 (Suppl. B):1998;B19-B24.
72. Clerk A., Fuller S.J., Michael A., Sugden P.H. Stimulation of "stress-regulated" mitogen-activated protein kinases (Stress-activated protein kinases/c-Jun N-terminal kinases and p38-mitogen-activated protein kinases) in perfused rat hearts by oxidative and other stresses. J Biol Chem. 273:1998;7228-7234.
73. Communal C., Colucci W.S., Singh K. p38 mitogen-activated protein kinase pathway protects adult rat ventricular myocytes against beta-adrenergic receptor-stimulated apoptosis. Evidence for Gi-dependent activation. J Biol Chem. 275:2000;19395-19400.
74. Turner N.A., Xia F., Azhar G., Zhang X., Liu L., Wei J.Y. Oxidative stress induces DNA fragmentation and caspase activation via the c-Jun NH2-terminal kinase pathway in H9c2 cardiac muscle cells. J Mol Cell Cardiol. 30:1998;1789-1801.