Extracellular superoxide dismutase transgene overexpression preserves postischemic myocardial function in isolated murine hearts

Circulation

Volumn 94, Issue 9 SUPPL., 1996, Pages

  Chen, Edward P ^a   Bittner, Hartmuth B ^a   Davis, R Duane ^a   Folz, Rodney J ^a   Van Trigt, Peter ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

antioxidants; free radicals; ischemia

Indexed keywords

SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HEART FUNCTION; HEART MUSCLE ISCHEMIA; HEART OUTPUT; HEART PRELOAD; HEART RATE; HEART STROKE VOLUME; HEART WORK; ISOLATED HEART; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENE; TRANSGENIC MOUSE;

ANIMALS; CARDIAC OUTPUT; HEART; HUMANS; MICE; MICE, TRANSGENIC; MYOCARDIAL ISCHEMIA; SUPEROXIDE DISMUTASE; TRANSGENES;

EID: 0010117025     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Freeman BA, Crapo JD. Biology of disease: free radicals and tissue injury. Lab Invest. 1982;5:412-425.
2. Hatori N, Sjoquist P, Marklund SL, Ryden L. Effects of recombinant human extracellular superoxide dismutase type C on myocardial infarct size in pigs. Free Radic Biol Med. 1992;13:221-230.
3. Sjoquist P, Marklund SL. Endothelium bound extracellular superoxide dismutase type C reduces damage in reperfused ischemic rat hearts. Cardiovasc Res. 1992;26:347-350.
4. Hatori N, Sjoquist P, Marklund SL, Pehrsson SK, Ryden L. Effects of recombinant human extracellular superoxide dismutase type C on myocardial reperfusion injury in isolated cold-arrested rat hearts. Free Radic Biol Med. 1992;13:137-142.
5. Werns SW, Lucchesi BR. Myocardial ischemia and reperfusion: the role of oxygen free radicals in tissue injury. Cardiovasc Drugs Ther. 1989;2:761-769.
6. McCord JM, Fridovich I. Superoxide dismutase: an enzymatic function for erythrocuprein (hemocuprein). J Biol Chem. 1969;244:6049-6055.
7. Jolly SR, Kane WJ, Bailie MB, Abrams G, Lucchesi BR. Canine myocardial reperfusion injury: its reduction by the combined administration of superoxide dismutase and catalase. Circ Res. 1984;54: 277-285.
8. Werns SW, Shea MJ, Driscoll EM, Cohen C, Abrams GD, Pitt B, Lucchesi BR. The independent effects of oxygen radical scavengers on canine infarct size reduction by superoxide dismutase but not catalase. Circ Res. 1985;56:895-898.
9. Tamura Y, Chi L, Driscoll EM, Hoff PT, Freeman BA, Gallagher KP, Lucchesi BR. Superoxide dismutase conjugated to a polyethylene glycol provides sustained protection against myocardial ischemia/reperfusion injury in canine heart. Circ Res. 1988;63:944-959.
10. Naslund U, Haggmark S, Johansson G, Marklund SL, Reiz S. Limitation of myocardial infarct size by superoxide dismutase as an adjunct to reperfusion after different durations of coronary occlusion in the pig. Circ Res. 1990;66:1294-1301.
11. Przyklenk K, Kloner RA. 'Reperfusion injury' by oxygen-derived free radicals? Effect of superoxide dismutase plus catalase, given at the time of reperfusion, on myocardial infarct size, contractile function, coronary vasculature, and regional myocardial blood flow. Circ Res. 1989;64:86-96.
12. 2-adrenergic receptor. Science. 1994;264:582-586.
13. Hewett TE, Grupp IL, Robbins J. Alpha-skeletal actin is associated with increased contractility in the mouse heart. Circ Res. 1994;74: 740-746.
14. 2 toxicity. Proc Natl Acad Sci USA. 1992;89:9715-9719.
15. Bittner HB, Chen EP, Campbell KA, Davis JW, Van Trigt P. A valid working heart preparation to study cardiac function and ischemia in murine hearts. Circulation. 1995;92(suppl I):I-322. Abstract.
16. Grupp IL, Subramaniam A, Hewett TE, Robbins J, Grupp G. Comparison of normal, hypodynamic and hyperdynamic mouse hearts using isolated work-performing heart preparations. Am J Physiol. 1993;265:H1401-H1410.
17. Glower DD, Spratt JA, Snow ND. Linearity of the Frank-Starling relationship in the intact heart: the concept of preload recraitable stroke work. Circulation. 1985;71:994-1009.
18. Das DK, Maulik N. Antioxidant effectiveness in ischemia-reperfusion tissue injury. Methods Enzymol. 1994;233:601-610.
19. Folz RJ, Crapo JD. Pulmonary oxygen toxicity. Curr Pulmonol. 1994;15:113-136.
20. Omar BA, McCord JM. Interstitial equilibrium of superoxide dismutase correlates with its protective effect in the isolated rabbit heart. J Mol Cell Cardiol. 1991;89:149-159.
21. McCord JM, Omar BA, Russell WJ. Sources of oxygen-derived radicals in ischemia-reperfusion. In: Hayashi E, Kondo M, Yoshikawa T, eds. Medical, Biochemical and Chemical Aspects of Free Radicals. Amsterdam, Netherlands: Elsevier Science Publishers; 1989:1113-1118.
22. Casale AS, Bulkley GB, Bulkley BH, Flaherty JT, Bott VL, Gardner TJ. Oxygen free radical scavengers protect the arrested, globally ischemic heart upon reperfusion. Surg Forum. 1983;34:313-316.
23. Myers CL, Weiss SJ, Kirsh MM, Shlafer M. Involvement of hydrogen peroxide and hydroxyl radical in the 'oxygen paradox': reduction of creatine kinase release by catalase, allopurinol or deferoxamine, but not by superoxide dismutase. J Mol Cell Cardiol. 1985;17:675-684.
24. Menasche P, Grousset C, Gaudel Y, Mouas C, Piwnica A. Enhancement of cardioplegia protection with the free radical scavenger peroxidase. Circulation. 1986;74(pt 2):III-138-III-144.