-
1
-
-
0031587276
-
The effects of artificial calcium buffers on calcium responses and glutamate-mediated excitotoxicity in cultured hippocampal neurons
-
Abdel-Hamid K.M., Baimbridge K.G. The effects of artificial calcium buffers on calcium responses and glutamate-mediated excitotoxicity in cultured hippocampal neurons. Neuroscience. 81:1997;673-687.
-
(1997)
Neuroscience
, vol.81
, pp. 673-687
-
-
Abdel-Hamid, K.M.1
Baimbridge, K.G.2
-
2
-
-
0036488223
-
Mitochondrial permeability transition and calcium dynamics in striatal neurons upon intense NMDA receptor activation
-
Alano C.C., Beutner G., Dirksen R.T., Gross R.A., Sheu S.S. Mitochondrial permeability transition and calcium dynamics in striatal neurons upon intense NMDA receptor activation. J. Neurochem. 80:2002;531-538.
-
(2002)
J. Neurochem.
, vol.80
, pp. 531-538
-
-
Alano, C.C.1
Beutner, G.2
Dirksen, R.T.3
Gross, R.A.4
Sheu, S.S.5
-
3
-
-
0025322132
-
Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease
-
(see comments)
-
Albin R.L., Young A.B., Penney J.B., Handelin B., Balfour R., Anderson K.D., Markel D.S., Tourtellotte W.W., Reiner A. Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease. (see comments) N. Engl. J. Med. 322:1990;1293-1298.
-
(1990)
N. Engl. J. Med.
, vol.322
, pp. 1293-1298
-
-
Albin, R.L.1
Young, A.B.2
Penney, J.B.3
Handelin, B.4
Balfour, R.5
Anderson, K.D.6
Markel, D.S.7
Tourtellotte, W.W.8
Reiner, A.9
-
4
-
-
0028793257
-
Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
-
Ankarcrona M., Dypbukt J.M., Bonfoco E., Zhivotovsky B., Orrenius S., Lipton S.A., Nicotera P. Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron. 15:1995;961-973.
-
(1995)
Neuron
, vol.15
, pp. 961-973
-
-
Ankarcrona, M.1
Dypbukt, J.M.2
Bonfoco, E.3
Zhivotovsky, B.4
Orrenius, S.5
Lipton, S.A.6
Nicotera, P.7
-
5
-
-
0032588769
-
Coenzyme Q10 administration and its potential for treatment of neurodegenerative diseases
-
Beal M.F. Coenzyme Q10 administration and its potential for treatment of neurodegenerative diseases. BioFactors. 9:1999;261-266.
-
(1999)
BioFactors
, vol.9
, pp. 261-266
-
-
Beal, M.F.1
-
6
-
-
0022446150
-
Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid
-
Beal M.F., Kowall N.W., Ellison D.W., Mazurek M.F., Swartz K.J., Martin J.B. Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid. Nature. 321:1986;168-171.
-
(1986)
Nature
, vol.321
, pp. 168-171
-
-
Beal, M.F.1
Kowall, N.W.2
Ellison, D.W.3
Mazurek, M.F.4
Swartz, K.J.5
Martin, J.B.6
-
7
-
-
0029153913
-
Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures
-
Bonfoco E., Krainc D., Ankarcrona M., Nicotera P., Lipton S.A. Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc. Natl. Acad. Sci. U. S. A. 92:1995;7162-7166.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 7162-7166
-
-
Bonfoco, E.1
Krainc, D.2
Ankarcrona, M.3
Nicotera, P.4
Lipton, S.A.5
-
8
-
-
0035889535
-
NMDA receptor function in mouse models of Huntington disease
-
Cepeda C., Ariano M.A., Calvert C.R., Flores-Hernandez J., Chandler S.H., Leavitt B.R., Hayden M.R., Levine M.S. NMDA receptor function in mouse models of Huntington disease. J. Neurosci. Res. 66:2001;525-539.
-
(2001)
J. Neurosci. Res.
, vol.66
, pp. 525-539
-
-
Cepeda, C.1
Ariano, M.A.2
Calvert, C.R.3
Flores-Hernandez, J.4
Chandler, S.H.5
Leavitt, B.R.6
Hayden, M.R.7
Levine, M.S.8
-
9
-
-
0034283877
-
Transcriptional dysregulation in Huntington's disease
-
Cha J.H. Transcriptional dysregulation in Huntington's disease. Trends Neurosci. 23:2000;387-392.
-
(2000)
Trends Neurosci.
, vol.23
, pp. 387-392
-
-
Cha, J.H.1
-
10
-
-
0032971311
-
Subtype-specific enhancement of NMDA receptor currents by mutant huntingtin
-
Chen N., Luo T., Wellington C., Metzler M., McCutcheon K., Hayden M.R., Raymond L.A. Subtype-specific enhancement of NMDA receptor currents by mutant huntingtin. J. Neurochem. 72:1999;1890-1898.
-
(1999)
J. Neurochem.
, vol.72
, pp. 1890-1898
-
-
Chen, N.1
Luo, T.2
Wellington, C.3
Metzler, M.4
McCutcheon, K.5
Hayden, M.R.6
Raymond, L.A.7
-
11
-
-
0034009242
-
Native N-methyl-D-aspartate receptors containing NR2A and NR2B subunits have pharmacologically distinct competitive antagonist binding sites
-
Christie J.M., Jane D.E., Monaghan D.T. Native N-methyl-D-aspartate receptors containing NR2A and NR2B subunits have pharmacologically distinct competitive antagonist binding sites. J. Pharmacol. Exp. Ther. 292:2000;1169-1174.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.292
, pp. 1169-1174
-
-
Christie, J.M.1
Jane, D.E.2
Monaghan, D.T.3
-
12
-
-
0028989602
-
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
-
DiFiglia M., Sapp E., Chase K., Schwarz C., Meloni A., Young C., Martin E., Vonsattel J.P., Carraway R., Reeves S.A.et al. Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons. Neuron. 14:1995;1075-1081.
-
(1995)
Neuron
, vol.14
, pp. 1075-1081
-
-
Difiglia, M.1
Sapp, E.2
Chase, K.3
Schwarz, C.4
Meloni, A.5
Young, C.6
Martin, E.7
Vonsattel, J.P.8
Carraway, R.9
Reeves, S.A.10
-
13
-
-
0022343684
-
Selective sparing of a class of striatal neurons in Huntington's disease
-
Ferrante R.J., Kowall N.W., Beal M.F., Richardson E.P. Jr., Bird E.D., Martin J.B. Selective sparing of a class of striatal neurons in Huntington's disease. Science. 230:1985;561-563.
-
(1985)
Science
, vol.230
, pp. 561-563
-
-
Ferrante, R.J.1
Kowall, N.W.2
Beal, M.F.3
Richardson, E.P.Jr.4
Bird, E.D.5
Martin, J.B.6
-
14
-
-
0030950980
-
Heterogeneous topographic and cellular distribution of huntingtin expression in the normal human neostriatum
-
Ferrante R.J., Gutekunst C.A., Persichetti F., McNeil S.M., Kowall N.W., Gusella J.F., MacDonald M.E., Beal M.F., Hersch S.M. Heterogeneous topographic and cellular distribution of huntingtin expression in the normal human neostriatum. J. Neurosci. 17:1997;3052-3063.
-
(1997)
J. Neurosci.
, vol.17
, pp. 3052-3063
-
-
Ferrante, R.J.1
Gutekunst, C.A.2
Persichetti, F.3
McNeil, S.M.4
Kowall, N.W.5
Gusella, J.F.6
MacDonald, M.E.7
Beal, M.F.8
Hersch, S.M.9
-
15
-
-
0032006449
-
The mitochondrial ADP/ATP carrier: Structural, physiological and pathological aspects
-
Fiore C., Trezeguet V., Le Saux A., Roux P., Schwimmer C., Dianoux A.C., Noel F., Lauquin G.J., Brandolin G., Vignais P.V. The mitochondrial ADP/ATP carrier: structural, physiological and pathological aspects. Biochimie. 80:1998;137-150.
-
(1998)
Biochimie
, vol.80
, pp. 137-150
-
-
Fiore, C.1
Trezeguet, V.2
Le Saux, A.3
Roux, P.4
Schwimmer, C.5
Dianoux, A.C.6
Noel, F.7
Lauquin, G.J.8
Brandolin, G.9
Vignais, P.V.10
-
16
-
-
0029966711
-
Multiplicity of glutamate receptor subunits in single striatal neurons: An RNA amplification study
-
Ghasemzadeh M.B., Sharma S., Surmeier D.J., Eberwine J.H., Chesselet M.F. Multiplicity of glutamate receptor subunits in single striatal neurons: an RNA amplification study. Mol. Pharmacol. 49:1996;852-859.
-
(1996)
Mol. Pharmacol.
, vol.49
, pp. 852-859
-
-
Ghasemzadeh, M.B.1
Sharma, S.2
Surmeier, D.J.3
Eberwine, J.H.4
Chesselet, M.F.5
-
17
-
-
0032575752
-
Mitochondria and apoptosis
-
Green D.R., Reed J.C. Mitochondria and apoptosis. Science. 281:1998;1309-1312.
-
(1998)
Science
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
18
-
-
85009226418
-
A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease
-
Group H.S. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology. 57:2001;397-404.
-
(2001)
Neurology
, vol.57
, pp. 397-404
-
-
Group, H.S.1
-
19
-
-
0032190391
-
The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): Comparison with huntingtin in rat and human
-
Gutekunst C.A., Li S.H., Yi H., Ferrante R.J., Li X.J., Hersch S.M. The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): comparison with huntingtin in rat and human. J. Neurosci. 18:1998;7674-7686.
-
(1998)
J. Neurosci.
, vol.18
, pp. 7674-7686
-
-
Gutekunst, C.A.1
Li, S.H.2
Yi, H.3
Ferrante, R.J.4
Li, X.J.5
Hersch, S.M.6
-
20
-
-
0027474041
-
Glutamate receptor-induced 45Ca2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration
-
Hartley D.M., Kurth M.C., Bjerkness L., Weiss J.H., Choi D.W. Glutamate receptor-induced 45Ca2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration. J. Neurosci. 13:1993;1993-2000.
-
(1993)
J. Neurosci.
, vol.13
, pp. 1993-2000
-
-
Hartley, D.M.1
Kurth, M.C.2
Bjerkness, L.3
Weiss, J.H.4
Choi, D.W.5
-
21
-
-
0033136692
-
A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration
-
Hodgson J.G., Agopyan N., Gutekunst C.A., Leavitt B.R., LePiane F., Singaraja R., Smith D.J., Bissada N., McCutcheon K., Nasir J., Jamot L., Li X.J., Stevens M.E., Rosemond E., Roder J.C., Phillips A.G., Rubin E.M., Hersch S.M., Hayden M.R. A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration. Neuron. 23:1999;181-192.
-
(1999)
Neuron
, vol.23
, pp. 181-192
-
-
Hodgson, J.G.1
Agopyan, N.2
Gutekunst, C.A.3
Leavitt, B.R.4
Lepiane, F.5
Singaraja, R.6
Smith, D.J.7
Bissada, N.8
McCutcheon, K.9
Nasir, J.10
Jamot, L.11
Li, X.J.12
Stevens, M.E.13
Rosemond, E.14
Roder, J.C.15
Phillips, A.G.16
Rubin, E.M.17
Hersch, S.M.18
Hayden, M.R.19
-
23
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
Huntington's Disease Collaborative Research Group A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell. 72:1993;971-983.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
24
-
-
0035861677
-
Zn(2+) induces permeability transition pore opening and release of pro- apoptotic peptides from neuronal mitochondria
-
Jiang D., Sullivan P.G., Sensi S.L., Steward O., Weiss J.H. Zn(2+) induces permeability transition pore opening and release of pro- apoptotic peptides from neuronal mitochondria. J. Biol. Chem. 276:2001;47524-47529.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 47524-47529
-
-
Jiang, D.1
Sullivan, P.G.2
Sensi, S.L.3
Steward, O.4
Weiss, J.H.5
-
25
-
-
0035887768
-
Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals
-
Jovanovic J.N., Sihra T.S., Nairn A.C., Hemmings H.C. Jr., Greengard P., Czernik A.J. Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals. J. Neurosci. 21:2001;7944-7953.
-
(2001)
J. Neurosci.
, vol.21
, pp. 7944-7953
-
-
Jovanovic, J.N.1
Sihra, T.S.2
Nairn, A.C.3
Hemmings, H.C.Jr.4
Greengard, P.5
Czernik, A.J.6
-
26
-
-
0035869341
-
Evidence for redox regulation of cytochrome C release during programmed neuronal death: Antioxidant effects of protein synthesis and caspase inhibition
-
Kirkland R.A., Franklin J.L. Evidence for redox regulation of cytochrome C release during programmed neuronal death: antioxidant effects of protein synthesis and caspase inhibition. J. Neurosci. 21:2001;1949-1963.
-
(2001)
J. Neurosci.
, vol.21
, pp. 1949-1963
-
-
Kirkland, R.A.1
Franklin, J.L.2
-
27
-
-
0035575858
-
Changes in cortical and striatal neurons predict behavioral and electrophysiological abnormalities in a transgenic murine model of Huntington's disease
-
Laforet G.A., Sapp E., Chase K., McIntyre C., Boyce F.M., Campbell M., Cadigan B.A., Warzecki L., Tagle D.A., Reddy P.H., Cepeda C., Calvert C.R., Jokel E.S., Klapstein G.J., Ariano M.A., Levine M.S., DiFiglia M., Aronin N. Changes in cortical and striatal neurons predict behavioral and electrophysiological abnormalities in a transgenic murine model of Huntington's disease. J. Neurosci. 21:2001;9112-9123.
-
(2001)
J. Neurosci.
, vol.21
, pp. 9112-9123
-
-
Laforet, G.A.1
Sapp, E.2
Chase, K.3
McIntyre, C.4
Boyce, F.M.5
Campbell, M.6
Cadigan, B.A.7
Warzecki, L.8
Tagle, D.A.9
Reddy, P.H.10
Cepeda, C.11
Calvert, C.R.12
Jokel, E.S.13
Klapstein, G.J.14
Ariano, M.A.15
Levine, M.S.16
Difiglia, M.17
Aronin, N.18
-
28
-
-
0029068332
-
NMDA receptor subunit mRNA expression by projection neurons and interneurons in rat striatum
-
Landwehrmeyer G.B., Standaert D.G., Testa C.M., Penney J.B. Jr., Young A.B. NMDA receptor subunit mRNA expression by projection neurons and interneurons in rat striatum. J. Neurosci. 15:1995;5297-5307.
-
(1995)
J. Neurosci.
, vol.15
, pp. 5297-5307
-
-
Landwehrmeyer, G.B.1
Standaert, D.G.2
Testa, C.M.3
Penney, J.B.Jr.4
Young, A.B.5
-
30
-
-
0033571743
-
Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease
-
Levine M.S., Klapstein G.J., Koppel A., Gruen E., Cepeda C., Vargas M.E., Jokel E.S., Carpenter E.M., Zanjani H., Hurst R.S., Efstratiadis A., Zeitlin S., Chesselet M.F. Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease. J. Neurosci. Res. 58:1999;515-532.
-
(1999)
J. Neurosci. Res.
, vol.58
, pp. 515-532
-
-
Levine, M.S.1
Klapstein, G.J.2
Koppel, A.3
Gruen, E.4
Cepeda, C.5
Vargas, M.E.6
Jokel, E.S.7
Carpenter, E.M.8
Zanjani, H.9
Hurst, R.S.10
Efstratiadis, A.11
Zeitlin, S.12
Chesselet, M.F.13
-
31
-
-
0027484673
-
Huntington's disease gene (IT15) is widely expressed in human rat tissues
-
Li S.-H., Schilling G., Young W.S. 3rd, Li X.-J., Margolis R.L., Stine O.C., Wagster M.V., Abbott M.H., Fanz M.L., Ranin N.G., Folstein S.E., Hedreen J.C., Ross C.A. Huntington's disease gene (IT15) is widely expressed in human rat tissues. Neuron. 11:1993;985-993.
-
(1993)
Neuron
, vol.11
, pp. 985-993
-
-
Li, S.-H.1
Schilling, G.2
Young III, W.S.3
Li, X.-J.4
Margolis, R.L.5
Stine, O.C.6
Wagster, M.V.7
Abbott, M.H.8
Fanz, M.L.9
Ranin, N.G.10
Folstein, S.E.11
Hedreen, J.C.12
Ross, C.A.13
-
32
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell. 91:1997;479-489.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
33
-
-
0344413576
-
Role of NR2B-type NMDA receptors in selective neurodegeneration in Huntington disease
-
Li L., Fan M., Icton C., Chen N., Leavitt B.R., Hayden M.R., Murphy T.H., Raymond L.A. Role of NR2B-type NMDA receptors in selective neurodegeneration in Huntington disease. Neurobiol. Aging. 24:2003;1113-1121.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 1113-1121
-
-
Li, L.1
Fan, M.2
Icton, C.3
Chen, N.4
Leavitt, B.R.5
Hayden, M.R.6
Murphy, T.H.7
Raymond, L.A.8
-
34
-
-
0035882151
-
Involvement of the brain-derived neurotrophic factor/TrkB pathway in neuroprotective effect of cyclosporin a in forebrain ischemia
-
Miyata K., Omori N., Uchino H., Yamaguchi T., Isshiki A., Shibasaki F. Involvement of the brain-derived neurotrophic factor/TrkB pathway in neuroprotective effect of cyclosporin A in forebrain ischemia. Neuroscience. 105:2001;571-578.
-
(2001)
Neuroscience
, vol.105
, pp. 571-578
-
-
Miyata, K.1
Omori, N.2
Uchino, H.3
Yamaguchi, T.4
Isshiki, A.5
Shibasaki, F.6
-
35
-
-
0033991004
-
Activation of apoptosis-linked caspase(s) in NMDA-injured brains in neonatal rats
-
Nath R., Scott M., Nadimpalli R., Gupta R., Wang K.K. Activation of apoptosis-linked caspase(s) in NMDA-injured brains in neonatal rats. Neurochem. Int. 36:2000;119-126.
-
(2000)
Neurochem. Int.
, vol.36
, pp. 119-126
-
-
Nath, R.1
Scott, M.2
Nadimpalli, R.3
Gupta, R.4
Wang, K.K.5
-
36
-
-
0034176843
-
Mitochondrial membrane potential and neuronal glutamate excitotoxicity: Mortality and millivolts
-
Nicholls D.G., Ward M.W. Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts. Trends Neurosci. 23:2000;166-174.
-
(2000)
Trends Neurosci.
, vol.23
, pp. 166-174
-
-
Nicholls, D.G.1
Ward, M.W.2
-
37
-
-
0032785021
-
Caspase structure, proteolytic substrates, and function during apoptotic cell death
-
Nicholson D.W. Caspase structure, proteolytic substrates, and function during apoptotic cell death. Cell Death Differ. 6:1999;1028-1042.
-
(1999)
Cell Death Differ.
, vol.6
, pp. 1028-1042
-
-
Nicholson, D.W.1
-
38
-
-
0036327065
-
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines
-
Panov A.V., Gutekunst C.A., Leavitt B.R., Hayden M.R., Burke J.R., Strittmatter W.J., Greenamyre J.T. Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines. Nat. Neurosci. 5:2002;731-736.
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 731-736
-
-
Panov, A.V.1
Gutekunst, C.A.2
Leavitt, B.R.3
Hayden, M.R.4
Burke, J.R.5
Strittmatter, W.J.6
Greenamyre, J.T.7
-
39
-
-
0032734206
-
D1 dopamine receptor-induced cyclic AMP-dependent protein kinase phosphorylation and potentiation of striatal glutamate receptors
-
Price C.J., Kim P., Raymond L.A. D1 dopamine receptor-induced cyclic AMP-dependent protein kinase phosphorylation and potentiation of striatal glutamate receptors. J. Neurochem. 73:1999;2441-2446.
-
(1999)
J. Neurochem.
, vol.73
, pp. 2441-2446
-
-
Price, C.J.1
Kim, P.2
Raymond, L.A.3
-
40
-
-
0035896592
-
Pro-caspase-8 is predominantly localized in mitochondria and released into cytoplasm upon apoptotic stimulation
-
Qin Z.H., Wang Y., Kikly K.K., Sapp E., Kegel K.B., Aronin N., DiFiglia M. Pro-caspase-8 is predominantly localized in mitochondria and released into cytoplasm upon apoptotic stimulation. J. Biol. Chem. 276:2001;8079-8086.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 8079-8086
-
-
Qin, Z.H.1
Wang, Y.2
Kikly, K.K.3
Sapp, E.4
Kegel, K.B.5
Aronin, N.6
Difiglia, M.7
-
41
-
-
20244375528
-
The messenger RNAs for the N-methyl-D-aspartate receptor subunits show region-specific expression of different subunit composition in the human brain
-
Rigby M., Le Bourdelles B., Heavens R.P., Kelly S., Smith D., Butler A., Hammans R., Hills R., Xuereb J.H., Hill R.G., Whiting P.J., Sirinathsinghji D.J. The messenger RNAs for the N-methyl-D-aspartate receptor subunits show region-specific expression of different subunit composition in the human brain. Neuroscience. 73:1996;429-447.
-
(1996)
Neuroscience
, vol.73
, pp. 429-447
-
-
Rigby, M.1
Le Bourdelles, B.2
Heavens, R.P.3
Kelly, S.4
Smith, D.5
Butler, A.6
Hammans, R.7
Hills, R.8
Xuereb, J.H.9
Hill, R.G.10
Whiting, P.J.11
Sirinathsinghji, D.J.12
-
42
-
-
0024400046
-
The quinolinic acid model of Huntington's disease: Locomotor abnormalities
-
Sanberg P.R., Calderon S.F., Giordano M., Tew J.M., Norman A.B. The quinolinic acid model of Huntington's disease: locomotor abnormalities. Exp. Neurol. 105:1989;45-53.
-
(1989)
Exp. Neurol.
, vol.105
, pp. 45-53
-
-
Sanberg, P.R.1
Calderon, S.F.2
Giordano, M.3
Tew, J.M.4
Norman, A.B.5
-
43
-
-
0033103523
-
Caspase-8 is required for cell death induced by expanded polyglutamine repeats
-
(see comments)
-
Sanchez I., Xu C.J., Juo P., Kakizaka A., Blenis J., Yuan J. Caspase-8 is required for cell death induced by expanded polyglutamine repeats. (see comments) Neuron. 22:1999;623-633.
-
(1999)
Neuron
, vol.22
, pp. 623-633
-
-
Sanchez, I.1
Xu, C.J.2
Juo, P.3
Kakizaka, A.4
Blenis, J.5
Yuan, J.6
-
44
-
-
0026689872
-
Activation and desensitization of N-methyl-D-aspartate receptors in nucleated outside-out patches from mouse neurones
-
Sather W., Dieudonne S., MacDonald J.F., Ascher P. Activation and desensitization of N-methyl-D-aspartate receptors in nucleated outside-out patches from mouse neurones. J. Physiol. 450:1992;643-672.
-
(1992)
J. Physiol.
, vol.450
, pp. 643-672
-
-
Sather, W.1
Dieudonne, S.2
MacDonald, J.F.3
Ascher, P.4
-
45
-
-
0034023864
-
Molecular mechanisms of calcium-dependent excitotoxicity
-
Sattler R., Tymianski M. Molecular mechanisms of calcium-dependent excitotoxicity. J. Mol. Med. 78:2000;3-13.
-
(2000)
J. Mol. Med.
, vol.78
, pp. 3-13
-
-
Sattler, R.1
Tymianski, M.2
-
46
-
-
0032851595
-
Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization
-
Sawa A., Wiegand G.W., Cooper J., Margolis R.L., Sharp A.H., Lawler J.F. Jr., Greenamyre J.T., Snyder S.H., Ross C.A. Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization. Nat. Med. 5:1999;1194-1198.
-
(1999)
Nat. Med.
, vol.5
, pp. 1194-1198
-
-
Sawa, A.1
Wiegand, G.W.2
Cooper, J.3
Margolis, R.L.4
Sharp, A.H.5
Lawler, J.F.Jr.6
Greenamyre, J.T.7
Snyder, S.H.8
Ross, C.A.9
-
47
-
-
0032529841
-
Altered Ca2+ signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: A model of Down's syndrome
-
Schuchmann S., Muller W., Heinemann U. Altered Ca2+ signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: a model of Down's syndrome. J. Neurosci. 18:1998;7216-7231.
-
(1998)
J. Neurosci.
, vol.18
, pp. 7216-7231
-
-
Schuchmann, S.1
Muller, W.2
Heinemann, U.3
-
48
-
-
0029034511
-
Widespread expression of Huntington's disease gene (IT15) protein product
-
Sharp A.H., Loev S.J., Schilling G., Li S.H., Li X.J., Bao J., Wagster M.V., Kotzuk J.A., Steiner J.P., Lo A.et al. Widespread expression of Huntington's disease gene (IT15) protein product. Neuron. 14:1995;1065-1074.
-
(1995)
Neuron
, vol.14
, pp. 1065-1074
-
-
Sharp, A.H.1
Loev, S.J.2
Schilling, G.3
Li, S.H.4
Li, X.J.5
Bao, J.6
Wagster, M.V.7
Kotzuk, J.A.8
Steiner, J.P.9
Lo, A.10
-
49
-
-
0028292804
-
GABA synapses formed in vitro by local axon collaterals of nucleus accumbens neurons
-
Shi W.-X., Rayport S. GABA synapses formed in vitro by local axon collaterals of nucleus accumbens neurons. J. Neurosci. 14:1994;4548-4560.
-
(1994)
J. Neurosci.
, vol.14
, pp. 4548-4560
-
-
Shi, W.-X.1
Rayport, S.2
-
50
-
-
15144345497
-
Pro-caspase-3 is a major physiologic target of caspase-8
-
Stennicke H.R., Jurgensmeier J.M., Shin H., Deveraux Q., Wolf B.B., Yang X., Zhou Q., Ellerby H.M., Ellerby L.M., Bredesen D., Green D.R., Reed J.C., Froelich C.J., Salvesen G.S. Pro-caspase-3 is a major physiologic target of caspase-8. J. Biol. Chem. 273:1998;27084-27090.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 27084-27090
-
-
Stennicke, H.R.1
Jurgensmeier, J.M.2
Shin, H.3
Deveraux, Q.4
Wolf, B.B.5
Yang, X.6
Zhou, Q.7
Ellerby, H.M.8
Ellerby, L.M.9
Bredesen, D.10
Green, D.R.11
Reed, J.C.12
Froelich, C.J.13
Salvesen, G.S.14
-
51
-
-
0033105949
-
High-affinity calcium indicators underestimate increases in intracellular calcium concentrations associated with excitotoxic glutamate stimulations
-
Stout A.K., Reynolds I.J. High-affinity calcium indicators underestimate increases in intracellular calcium concentrations associated with excitotoxic glutamate stimulations. Neuroscience. 89:1999;91-100.
-
(1999)
Neuroscience
, vol.89
, pp. 91-100
-
-
Stout, A.K.1
Reynolds, I.J.2
-
52
-
-
0032150860
-
Glutamate-induced neuron death requires mitochondrial calcium uptake
-
Stout A.K., Raphael H.M., Kanterewicz B.I., Klann E., Reynolds I.J. Glutamate-induced neuron death requires mitochondrial calcium uptake. Nat. Neurosci. 1:1998;366-373.
-
(1998)
Nat. Neurosci.
, vol.1
, pp. 366-373
-
-
Stout, A.K.1
Raphael, H.M.2
Kanterewicz, B.I.3
Klann, E.4
Reynolds, I.J.5
-
55
-
-
0034733607
-
Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells
-
Wellington C.L., Singaraja R., Ellerby L., Savill J., Roy S., Leavitt B., Cattaneo E., Hackam A., Sharp A., Thornberry N., Nicholson D.W., Bredesen D.E., Hayden M.R. Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells. J. Biol. Chem. 275:2000;19831-19838.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 19831-19838
-
-
Wellington, C.L.1
Singaraja, R.2
Ellerby, L.3
Savill, J.4
Roy, S.5
Leavitt, B.6
Cattaneo, E.7
Hackam, A.8
Sharp, A.9
Thornberry, N.10
Nicholson, D.W.11
Bredesen, D.E.12
Hayden, M.R.13
-
56
-
-
0037107151
-
Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease
-
Wellington C.L., Ellerby L.M., Gutekunst C.A., Rogers D., Warby S., Graham R.K., Loubser O., van Raamsdonk J., Singaraja R., Yang Y.Z., Gafni J., Bredesen D., Hersch S.M., Leavitt B.R., Roy S., Nicholson D.W., Hayden M.R. Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease. J. Neurosci. 22:2002;7862-7872.
-
(2002)
J. Neurosci.
, vol.22
, pp. 7862-7872
-
-
Wellington, C.L.1
Ellerby, L.M.2
Gutekunst, C.A.3
Rogers, D.4
Warby, S.5
Graham, R.K.6
Loubser, O.7
Van Raamsdonk, J.8
Singaraja, R.9
Yang, Y.Z.10
Gafni, J.11
Bredesen, D.12
Hersch, S.M.13
Leavitt, B.R.14
Roy, S.15
Nicholson, D.W.16
Hayden, M.R.17
-
57
-
-
0035084172
-
Dual involvement of coenzyme Q10 in redox signaling and inhibition of death signaling in the rat heart mitochondria
-
Yamamura T., Otani H., Nakao Y., Hattori R., Osako M., Imamura H., Das D.K. Dual involvement of coenzyme Q10 in redox signaling and inhibition of death signaling in the rat heart mitochondria. Antioxid. Redox Signal. 3:2001;103-112.
-
(2001)
Antioxid. Redox Signal.
, vol.3
, pp. 103-112
-
-
Yamamura, T.1
Otani, H.2
Nakao, Y.3
Hattori, R.4
Osako, M.5
Imamura, H.6
Das, D.K.7
-
58
-
-
0023690166
-
NMDA receptor losses in putamen from patients with Huntington's disease
-
Young A.B., Greenamyre J.T., Hollingsworth Z., Albin R., D'Amato C., Shoulson I., Penney J.B. NMDA receptor losses in putamen from patients with Huntington's disease. Science. 241:1988;981-983.
-
(1988)
Science
, vol.241
, pp. 981-983
-
-
Young, A.B.1
Greenamyre, J.T.2
Hollingsworth, Z.3
Albin, R.4
D'Amato, C.5
Shoulson, I.6
Penney, J.B.7
-
59
-
-
0035154912
-
Mutant huntingtin enhances excitotoxic cell death
-
Zeron M.M., Chen N., Moshaver A., Lee A.T., Wellington C.L., Hayden M.R., Raymond L.A. Mutant huntingtin enhances excitotoxic cell death. Mol. Cell. Neurosci. 17:2001;41-53.
-
(2001)
Mol. Cell. Neurosci.
, vol.17
, pp. 41-53
-
-
Zeron, M.M.1
Chen, N.2
Moshaver, A.3
Lee, A.T.4
Wellington, C.L.5
Hayden, M.R.6
Raymond, L.A.7
-
60
-
-
0037075624
-
Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease
-
Zeron M.M., Hansson O., Chen N., Wellington C.L., Leavitt B.R., Brundin P., Hayden M.R., Raymond L.A. Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease. Neuron. 33:2002;849-860.
-
(2002)
Neuron
, vol.33
, pp. 849-860
-
-
Zeron, M.M.1
Hansson, O.2
Chen, N.3
Wellington, C.L.4
Leavitt, B.R.5
Brundin, P.6
Hayden, M.R.7
Raymond, L.A.8
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