Calcium induced release of mitochondrial cytochrome c by different mechanisms selective for brain versus liver

Cell Death and Differentiation

Volumn 6, Issue 9, 1999, Pages 825-832

  Andreyev, Alexander ^a   Fiskum, Gary ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Calcium; Cytochrome c; Electron microscopy; Immunoblot; Membrane permeability transition; Mitochondria

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CYCLOSPORIN A; CYTOCHROME C; MAGNESIUM ION;

ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; CONTROLLED STUDY; ENZYME RELEASE; LIVER MITOCHONDRION; MALE; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE SPECIFICITY;

ANIMALIA;

EID: 0032831667     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400565     Document Type: Article

References (57)

1. Green DR and Reed JC (1998) Mitochondria and apoptosis. Science 281:1309-1312
2. Susin SA, Zamzami N and Kroemer G (1998) Mitochondria as regulators of apoptosis: doubt no more. Biochim. Biophys. Acta. 1366:151-165
3. Kantrow SP and Piantadosi CA (1997) Release of cytochrome c from liver mitochondria during permeability transition. Biochem. Biophys. Res. Commun. 232:669-671
4. Scarlett JL and Murphy MP (1997) Release of apoptogenic proteins from the mitochondrial intermembrane space during the mitochondrial permeability transition. FEBS Lett 418: 282-286
5. Petit PX, Goubern M, Diolez P, Susin SA, Zamzami N and Kroemer G (1998) Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: the impact of irreversible permeability transition. FEBS Lett 426: 111-116
6. Andreyev AY, Fahy B and Fiskum G (1998) Cytochrome c release from brain mitochondria is independent of the mitochondrial permeability transition. FEBS Lett. 439: 373-376
7. Yang JC and Cortopassi GA (1998) Induction of the mitochondrial permeability transition causes release of the apoptogenic factor cytochrome c. Free Radic. Biol. Med. 24: 624-631
8. 2+ ions. J. Cell. Biol. 143: 217-224
9. Gross A, Yin XM, Wang K, Wei MC, Jockel J, Milliman C, Erdjument-Bromage H, Tempst P and Korsmeyer SJ (1999) Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death. J. Biol. Chem. 274: 1156-1163
10. Man Z, Bhalla K, Pantazis P, Hendrickson EA and Wyche JH (1999) Cif (Cytochrome c efflux-inducing factor) activity is regulated by bcl-2 and caspases and correlates with the activation of Bid. Mol. Cell. Biol. 19: 1381-1389
11. Jacobs EE and Sanadi DR (1960) Phosphorylation coupled to electron transport mediated by high potential electron carriers. Biochim. Biophys. Acta. 38: 12-33
12. Chappell JB and Crofts AR (1965). Calcium ion accumulation and volume changes of isolated liver mitochondria. Biochem. J. 95: 387-392
13. Pfeiffer DR, Gudz TI, Novgorodov SA and Erdahl WL (1995) The peptide mastoparan is a potent facilitator of the mitochondrial permeability transition. J. Biol. Chem. 270: 4923-4932
14. Skulachev VP (1997) Membrane-linked systems preventing superoxide formation. Bioscience Reports 17: 347-257
15. Kroemer G, Zamzami N and Susin SA (1997) Mitochondrial control of apoptosis. Immun. Today 18: 44-51
16. Broekemeier KM, Dempsey ME and Pfeiffer DR (1989) Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria. J. Biol. Chem. 264: 7826-7830
17. Zoratti M and Szabò I (1995) The mitochondrial permeability transition. Biochim. Biophys. Acta. 1241: 139-176
18. Bernardi P (1996) The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death. Biochim. Biophys. Acta. 1275: 5-9
19. Vercesi AE, Kowaltowski AJ, Grijalba MT, Meinicke AR and Castilho RF (1997) The role of reactive oxygen species in mitochondrial permeability transition. Biosci. Rep. 17: 43-52
20. Hunter DR, Haworth RA and Southard JH (1976) Relationship between configuration, function, and permeability in calcium-treated mitochondria. J. Biol. Chem. 251: 5069-5077
21. Vander Heiden MG, Chandel NS, Williamson EK, Schumacker PT and Thompson CR (1997) Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria. Cell 91: 627-637
22. Bossy-Wetzel E, Newmeyer DD and Green DR (1998) Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. EMBO J. 17: 37-49
23. Zhuang J, Dinsdale D and Cohen GM (1998) Apoptosis, in human monocytic THP. 1 cells, results in the release of cytochrome c from mitochondria prior to their ultracondensation, formation of outer membrane discontinuities and reduction in inner membrane potential. Cell Death Differ. 5: 953-962
24. Kristal BS and Dubinsky JM (1997) Mitochondrial permeability transition in central nervous system: induction by calcium cyclin-dependent and -independent pathways. J. Neurochem. 69: 524-538
25. Berman SB, Watkins SW and Hastings TG (1998) Evidence that brain mitochondria do not readily undergo permeability transition. Soc. Neurosci. Abstr. 24: 553
26. Fiskum G, Murphy AN and Beal MF (1999) Mitochondria in neurodegeneration: Acute ischemia and chronic neurodegenerative diseases. J. Cereb. Blood Flow Metab. 19: 351-369
27. Murphy AN, Fiskum G and Beal MF (1999) Mitochondria in neurodegeneration: Bioenergetic function in cell life and death. J. Cereb. Blood Flow Metab. 19: 231-245
28. Dugan LL, Sensi SL, Canzoniero LMT, Handran SD, Rothman SM, Lin T-S, Goldberg MP and Choi DW (1995) Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D aspartate. J. Neurosci. 15: 6377-6388
29. Ankarcrona M, Dypbukt JM, Bonfoco E, Zhivotovsky B, Orrenius S, Lipton SA and Nicotera P (1995) Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron. 15: 961-973
30. Budd SL and Nicholls DG (1996) Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells. J. Neurochem. 67: 2282-2291
31. Stout AK, Raphael HM, Kanterewica BI, Klann E and Reynolds IJ (1998) Glutamate-induced neuronal cell death is blocked by inhibition of mitochondrial calcium uptake with FCCP. Nature Neurosci. (in press)
32. Kruman II and Mattson MP (1999) Pivotal role of mitochondrial calcium uptake in neural cell apoptosis and necrosis. J. Neurochem. 72: 529-540
33. Lemasters JJ, Nieminen AL, Qian T, Trost LC, Elmore SP, Nishimura Y, Crowe RA, Cascio WE, Bradham CA, Brenner DA and Herman B (1998b) The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy. Biochim. Biophys. Acta. 1366: 177-196
34. Fontaine E, Eriksson O, Ichas F and Bernardi P (1998) Regulation of the permeability transition pore in skeletal muscle mitochondria. Modulation by electron flowthrough the respiratory chain complex I. J. Biol. Chem. 273: 12662-12668
35. Walter DH, Haendeler J, Galle J, Zeiher AM and Dimmeler S (1998) Cyclosporin A inhibits apoptosis of human endothelial cells by preventing release of cytochrome C from mitochondria. Circulation 98: 1153-1157
36. Yang J, Liu X, Bhalla K, Kim CN, Ibrado AM, Cai J, Peng TI, Jones DP and Wang X (1997) Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275: 1129-1132
37. Kluck RM, Bossy-Wetzel E, Green DR and Newmeyer DD (1997) The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275: 1132-1136
38. Cai J and Jones DP (1998) Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss. J. Biol. Chem. 237: 11401-11404
39. Finucane DM, Bossy-Wetzel E, Waterhouse NJ, Cotter TG and Green DR (1999) Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL. J. Biol. Chem. 274: 2225-2233
40. Bradham CA, Qian T, Streetz K, Trautwein C, Brenner DA and Lemasters JJ (1998) The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release. Mol. Cell. Biol. 18: 6353-6364
41. Lemasters JJ, Qian T, Elmore SP, Trost LC, Nishimura Y, Herman B, Bradham CA, Brenner DA and Nieminen AL (1998a) Confocal microscopy of the mitochondrial permeability transition in necrotic cell killing, apoptosis and autophagy. Biofactors 8: 283-285
42. Qian T, Herman B and Lemasters JJ (1999) The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed 1o Br-A23187. Toxicol. Appl. Pharmacol. 154: 117-125
43. Uchino H, Elmer E, Uchino K, Li PA, He QP, Smith ML and Siesjö BK (1998) Amelioration by cyclosporin A of brain damage in transient forebrain ischemia n the rat. Brain Res 812: 216-226
44. Friberg H, Ferrand-Drake M, Bengtsson F, Halestrap AP and Wieloch T (1998) Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death. J. Neurosci. 18: 5151-5159
45. 2+-induced release of apoptogenic cytochrome c. J. Neurochem. 72: S52C
46. Friberg H, Connern C, Halestrap AP and Wieloch T (1999) Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability. J. Neurochem. 72: 2488-2497
47. Susin SA, Zamzami N, Castedo M, Hirsch T, Marchetti P, Macho A, Daugas E, Geuskens M and Kroemer G (1996) Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J. Exp. Med. 184: 1331-1341
48. Murphy AN, Bredesen DE, Cortopassi G, Wang E and Fiskum G (1996) Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria. Proc. Natl. Acad. Sci. USA 93: 9893-9898
49. Shimizu S, Eguchi Y, Kamiike W, Funahashi Y, Mignon A, Lacronique V, Matsuda H and Tsujimoto Y (1998) Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux. Proc. Natl. Acad. Sci. USA 95: 1455-1459
50. Halestrap AP, Kerr PM, Javadov S and Woodfield KY (1998) Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart. Biochim. Biophys. Acta. 1366: 79-94
51. Pastorino JG, Simbula G, Yamamoto K, Glascott Jr PA, Rothman RJ and Farber JL (1996) The cytotoxicity of tumor necrosis factor depends on induction of the mitochondrial permeability transition. J. Biol. Chem. 271: 29792-29798
52. Mannella CA (1998) Conformational changes in the mitochondrial channel protein. VDAC, and their functional implications. J. Struct. Biol. 121: 207-218
53. Shimizu S, Narita M and Tsujimoto Y (1999) Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature 399: 483-487
54. Reed JC, Jurgensmeier JM and Matsuyama S (1998) Bcl-2 family proteins and mitochondria. Biochim. Biophys. Acta. 1366: 127-137
55. Schnaitman C and Greenwalt JW (1968) Enzymatic properties of the inner and outer membranes of rat liver mitochondria. J. Cell. Biol. 38: 158-175
56. Rosenthal RE, Hamud F, FiskumG, Vardhese PJ and Sharpe S (1987) Cerebral ischemia and reperfusion: prevention of brain mitochondrial injury by lidoflazine. J. Cereb. Blood. Flow Metab. 7: 752-758
57. Skarkowska L and Klingenberg M (1963) On the role of ubiquinone in mitochondria. Biochem. Z. 338: 674-697