Cdk inhibition in human cells compromises Chk1 function and activates a DNA damage response

Cancer Research

Volumn 65, Issue 3, 2005, Pages 780-786

  Maude, Shannon L ^a   Enders, Greg H ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 HYDROXYSTAUROSPORINE; ATM PROTEIN; ATR PROTEIN; CEP 3891; CHECKPOINT KINASE 1; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; ETOPOSIDE; HISTONE H2A; OLOMOUCINE; ROSCOVITINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA REPLICATION; DOWN REGULATION; ENZYME ACTIVITY; FIBROBLAST; HUMAN; HUMAN CELL; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA INTERFERENCE;

CDC2 PROTEIN KINASE; CDC2-CDC28 KINASES; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASES; DNA DAMAGE; DNA-BINDING PROTEINS; DOWN-REGULATION; ENZYME INHIBITORS; HELA CELLS; HISTONES; HUMANS; KINETIN; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PURINES; TUMOR SUPPRESSOR PROTEINS;

EID: 13444268947     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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