Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects

EMBO Journal

Volumn 22, Issue 3, 2003, Pages 713-723

  Zachos, George ^a   Rainey, Michael D ^a   Gillespie, David A F ^b  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Cell survival; Checkpoints; Chk1; DNA damage; DNA replication

Indexed keywords

CHECKPOINT KINASE 1; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE G2 PHASE; CELL DIVISION; CELL KILLING; CELL SURVIVAL; DNA DAMAGE; DNA METABOLISM; DNA REPLICATION; DNA STRUCTURE; DNA SYNTHESIS; ENZYME INHIBITION; GENE DUPLICATION; GENE TARGETING; IONIZING RADIATION; LYMPHOMA CELL LINE; MITSUNOBU REACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION;

AMINO ACID SEQUENCE; ANIMALS; APHIDICOLIN; CELL DIVISION; CELL SURVIVAL; CHICKENS; DNA DAMAGE; DNA REPLICATION; ENZYME INHIBITORS; GENE TARGETING; GENES, CDC; HUMANS; LYMPHOMA, B-CELL; MOLECULAR SEQUENCE DATA; PROTEIN KINASES; RADIATION, IONIZING; SEQUENCE ALIGNMENT; TUMOR CELLS, CULTURED;

ANIMALIA; METAZOA;

EID: 0037415735     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg060     Document Type: Article

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