Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5

European Journal of Biochemistry

Volumn 243, Issue 1-2, 1997, Pages 527-536

  Meijer, Laurent ^a   Borgne, Annie ^a   Mulner, Odile ^a   Chong, James P J ^b   Blow, J Julian ^b   Inagaki, Naoyuki ^c   Inagaki, Masaki ^c   Delcros, Jean Guy ^d   Moulinoux, Jacques Philippe ^d  

^a STATION BIOLOGIQUE   (France)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^d CNRS   (France)

Author keywords

Anti tumor agent; Cell cycle; Cyclin dependent kinase; Kinase inhibitor; Purine

Indexed keywords

CYCLIN DEPENDENT KINASE; ELONGATION FACTOR; PURINE DERIVATIVE; ROSCOVITINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTERIAS; CELL CYCLE; CELL DIVISION; CONTROLLED STUDY; CYTOTOXICITY; DNA SYNTHESIS; ENZYME INHIBITION; IN VITRO STUDY; LEUKEMIA L 1210; NONHUMAN; OOCYTE; OOCYTE MATURATION; PRIORITY JOURNAL; PROPHASE; SEA URCHIN; XENOPUS;

EID: 0031037714     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1997.t01-2-00527.x     Document Type: Article

References (86)

1. Murray, A. & Hunt, T. (1993) in The cell cycle - an introduction, W. H. Freeman and Company, New York.
2. Fantes, P. & Brooks, R. (editors) (1994) in The cell cycle - a practical approach, IRL Press, Oxford.
3. Glover, D., Hall, A. & Hastie, N. (eds) (1994) J. Cell Sci. Suppl. 18.
4. Hu, V. W. (ed.) (1994) in The cell cyle. Regulators, targets, and clinical applications, Plenum Press, New York.
5. Meijer, L., Guidet, S. & Tung, H. Y. L. (eds) (1995) in Progress in cell cycle research, vol. 1, Plenum Press, New York.
6. Grana, X. & Reddy, E. P. (1995) Oncogene 11, 211-219.
7. Gould, K. L. (1995) in Protein kinases (Woodget, J. R., ed.) ch. 5, pp. 149-176, IRL Press, Oxford.
8. Morgan, D. O. (1995) Nature 374, 131-134.
9. Pines, J. (1995) Biochem. J. 308, 697-711.
10. Van den Heuvel, S. & Harlow, E. (1993) Science 262, 2050-2054.
11. De Bondt, H. L., Rosenblatt, J., Jancarik, J., Jones, H. D., Morgan, D. O. & Kim, S. H. (1993) Nature 363, 595-602.
12. Jeffrey, P. D., Russo, A. A., Polyak, K., Gibbs, E., Hurwitz, J., Massagué, J. & Pavletich, N. P. (1995) Nature 376, 313-320.
13. Cordon-Cardo, C. (1995) Am. J. Pathol. 147, 545-560.
14. Karp, J. E. & Broder, S. (1995) Nat. Med. 1, 309-320.
15. Yang, Z. Y., Perkins, N. D., Ohno, T., Nabel, E. G. & Nabel, G. J. (1995) Nat. Med. 1, 1052-1056.
16. Rialet, V. & Meijer, L. (1991) Anticancer Res. 11, 1581-1590.
17. Gadbois, D. M., Hamaguchi, J. R., Swank, R. A. & Bradbury, E. M. (1992) Biochem. Biophys. Res. Commun. 184, 80-85.
18. Kitagawa, M., Okabe, T., Ogino, H., Matsumoto, H., Suzuki-Takahashi, I., Kokubo, T., Higashi, H., Saitoh, S., Taya, Y., Yastida, H., Ohba, Y., Nishimura, S., Tanaka, N. & Okuyama, A. (1993) Oncogene 8, 2425-2432.
19. Kitagawa, M., Higashi, H., Suzuki-Takahashi, I., Okabe, T., Ogino, H., Taya, Y., Nishimura, S. & Okuyama, A. (1994) Oncogene 9, 2549-2557.
20. Someya, A., Tanaka, N. & Okuyama, A. (1994) Biochem. Biophys. Res. Commun. 198, 536-545.
21. Kaur, G., Stetler-Stevenson, M., Sehers, S., Worland, P., Sedlacek, H., Myers, C., Czech, J., Naik, R. & Sausville, E. (1992) J. Natl Cancer Inst. 84, 1736-1740.
22. Worland, P. J., Kaur, G., Stetler-Stevenson, M., Sebers, S., Sartor, O. & Sausville, E. A. (1993) Biochem. Pharmacol. 46, 1831-1840.
23. Losiewiecz, M. D., Carlson, B. A., Kaur, G., Sausville, E. A. & Worland, P. J. (1994) Biochem. Biophys. Res. Commun. 201, 589-595.
24. Bojanowski, K., Nishio, K., Fukuda, M., Larsen, A. K. & Saijo, N. (1994) Biochem. Biophys. Res. Commun. 203, 1574-1580.
25. Parker, C. W., Entsch, B. & Letham, D. S. (1986) Phytochemistry 25, 303-310.
26. Glab, N., Labidi, H., Qin, L.-X., Trehin, C., Bergounioux, C. & Meijer, L. (1994) FEBS Lett. 353, 207-214.
27. Vesely, J., Havlicek, L., Strnad, M., Blow, J. J., Donella-Deana, A., Pinna, L., Letham, D. S., Kato, J. Y. Détivaud, L., Leclerc, S. & Meijer, L. (1994) Eur. J. Biochem. 224, 771-786.
28. Abraham, R. T., Acquarone, M., Andersen, A., Asensi, A., Bellé, R., Berger, F., Bergounioux, C., Brunn, G., Buquet-Fagot, C., Fagot, D., Glab, N., Goudeau, H., Goudeau, M., Guerrier, P., Houghton, P. J., Hendriks, H., Kloareg, B., Lippai, M., Marie, D., Maro, B., Meijer, L., Mester, J., Mulner-Lorillon, O., Poulet, S. A., Schierenberg, E., Schutte, B., Vaulot, D. & Verlhac, M. H. (1995) Biol. Cell 83, 105-120.
29. Meijer, L., (1995) in Progress in cell cycle research (Meijer, L., Guidet, S. & Tung, H. Y. L., eds) vol. 1, pp. 351-363, Plenum Press, New York.
30. Meijer, L. (1996) Trends Cell Biol. 6, 393-397.
31. Schulze-Gahmen, U., Brandsen, J., Jones, H. D., Morgan, D. O., Meijer, L., Vesely, J. & Kim, S. H. (1995) Proteins: Struct. Funct. Genet. 22, 378-391.
32. Ongkeko, W., Ferguson, D. J. P., Harris, A. L., & Norbury, C. (1995) J. Cell Sci. 108, 2897-2904.
33. Park, D. S., Farinelli, S. E. & Greene, L. A. (1996) J. Biol. Chem. 271, 8161-8169.
34. Azevedo, W. F. Jr, Leclerc, S., Meijer, L., Havlicek, L., Strnad, M. & Kim, S. H. (1997) Eur. J. Biochem. 243, 518-526.
35. Azzi, L., Meijer, L., Ostvold, A. C., Lew, J. & Wang, J. H. (1994) J. Biol. Chem. 269, 13279-13288.
36. Baratte, B., Meijer, L., Galaktionov, K. & Beach, D. (1992) Anticancer Res. 12, 873-880.
37. Richardson, H. K., Stueland, C. S., Thomas, J. & Reed, S. I. (1990) Genes Dev. 4, 1332-1344.
38. Lew, J., Beaudette, K., Litwin, C. M. E. & Wang, J. H. (1992) J. Biol. Chem. 207, 13383-13390.
39. Meyerson, M. & Harlow, E. (1994) Mol. Cell. Biol. 14, 2077-2086.
40. Charest, D. L., Mordret, G., Harder, K. W., Jirik, F. & Pelech, S. L. (1993) Mol. Cell. Biol. 13, 4679-4690.
41. Bianchi, M. W., Guivarc'h, D., Thomas, M., Woodgett, J. R. & Kreis, M. (1994) Mol. Gen. Genet. 242, 337-345.
42. Kallen, R. G., Smith, J. E., Sheng, Z. & Tung, H. Y. L. (1990) Biochem. Biophys. Res. Commun. 168, 616-624.
43. Pondaven, P., Meijer, L. & Beach, D. (1990) Genes Der. 4, 9-17.
44. Blow, J. J. & Laskey, R A. (1986) Cell 47, 577-587.
45. Blow, J. J. (1993) J. Cell Biol. 122, 993-1002.
46. Mulner-Lorillon, O., Minella, O., Cormier, P., Capony, J.-C., Cavadore, J.-C., Morales, J., Poulhe, R. & Bellé, R. (1994) J. Biol. Chem. 269, 20201-20207.
47. Grever, M. R., Schepartz, S. A. & Chabner, B. A. (1992) Semin. Oncol. 19, 622-638.
48. Scudiero, D. A., Shoemaker, R. H., Paull, K. D., Monks, A., Tierney, S., Nofziger, T. H., Currens, M. J., Seniff, D. & Boyd, M. R. (1988) Cancer Res. 48, 4827-4833.
49. Basu, H. S., Sturkenboom, M. C. J. M., Delcros, J. G., Csokan, P. P., Szollosi, J., Feuerstein, B. G. & Marton, L. J. (1992) Biochem. J. 232, 723-727.
50. Tsujimura, K., Ogawara, M., Takeuchi, Y., Imajoh-Ohmi, S., Ha, M. H. & Inaguki, M. (1994) J. Biol. Chem. 269, 31097-31106.
51. Meijer, L. & Mordret, G. (1994) Semin. Dev. Biol. 5, 165-171.
52. Izumi, T. & Maller, J. L. (1995) Mol. Biol. Cell 6, 215-226.
53. Hoffmann, I. & Karsenti, K. (1994) J. Cell Sci. Suppl. 18, 75-79.
54. Strausfeld, U., Fernandez, A., Capony, J. P., Girard, K., Lautredou, N., Derancourt, J., Labbe, J. C. & Lamb, N. J. C. (1994) J. Biol. Chem. 269, 5989-6000.
55. Tang, Z., Coleman, T. R. & Dunphy, W. G. (1993) EMBO J. 12, 3427-3436.
56. McGowan, C. H. & Russell, P. (1995) EMBO J. 14, 2166-2175.
57. Mueller, P. R., Coleman, T. R. & Dunphy, W. G. (1995) Mol. Biol. Cell 6, 119-134.
58. Parker, L. L., Sylvestre, P. J., Byrnes III, M. J., Liu, F. & Piwnica-Worms (1995) Proc. Natl Acad. Sci. USA 92, 9638-9642.
59. Watanabe, N., Broome, M. & Hunter, T. (1995) EMBO J. 14, 1878-1891.
60. Meyerson, M., Enders, G. H., Wu, C. L., Su, L. K., Gorka, C., Nelson, C., Harlow, K. & Tsai, L. H. (1992) EMBO J. 11, 2909-2917.
61. Misteli, T. & Warren, G. (1995) J. Cell Sci. 108, 2715-2727.
62. Rudolph, B., Saffrich, R., Zwicker, J., Henglein, B., Müller, R., Ansorge, W. & Eilers, M. (1996) EMBO J. 15, 3065-3076.
63. Lorca, T., Labbé, J. C., Devault, A., Fesquet, D., Strausfeld, U., Nilsson, J., Nygren, P. A., Whlen, M., Cavadore, J. C. & Dorée, M. (1992) J. Cell Sci. 102, 55-62.
64. Lahavbaratz, S., Sudakin, V., Ruderman, J. V. & Hershko, A. (1995) Proc. Natl Acad. Sci. USA 92, 9303-9307.
65. Lowe, S. W., Ruley, H. E., Jacks, T. & Housman, D. E. (1993) Cell 74, 957-967.
66. Fisher, D. E. (1994) Cell 78, 539-542.
67. Smets, L. A. (1994) Anti-Cancer Drugs 5, 3-9.
68. Darzynkiewicz, Z. (1995) J. Cell. Biochem. 58, 151-159.
69. Hensey, C. & Gautier, J. (1995) in Progress in cell cycle research (Meijer, L., Guidet, S. & Tung, H. Y. L., eds) vol. 1, pp. 149-162, Plenum Press, New York.
70. Kondo, S. (1995) J. Radiat. Res. 36, 56-62.
71. Enoch, T. & Norbury, C. (1995) Trends Biochem. Sci. 20, 426-430.
72. Meikrantz, W., Gisselbrecht, S., Tam, S. W. & Schlegel, R. (1994) Proc. Natl Acad. Sci. USA 91, 3754-3758.
73. Shi, L., Nishioka, W. K., Th'ng, J., Bradbury, E. M., Litchfield, D. W. & Greenberg, A. H. (1994) Science 263, 1143-1145.
74. Fotedar, R. Flatt, J., Gupta, S., Margolis, R. L., Fittzgerald, P., Messier, H. & Fotedar, A. (1995) Mol. Cell. Biol. 15, 932-942.
75. Lazebnik, Y. A., Cole, S., Cooke, C. A., Nelson, W. G. & Earnshaw, W. C. (1993). J. Cell Biol. 123, 7-22.
76. Norbury, C., MacFarlane, M., Fearnhead, H. & Cohen, G. M. (1994) Biochem. Biophys. Res. Commun. 202, 1400-1406.
77. Oberhammer, F. A., Hochegger, K., Fröschl, G., Tiefenbacher, R. & Pavelka, M. (1994) J. Cell Biol. 126, 827-837.
78. Clarke, A. R., Purdie, C. A., Harrison, D. J., Morris, R. G., Bird, C. C., Hooper, M. L. & Wyllie, A. H. (1993) Nature 362, 849-852.
79. Yonish-Rouach, K., Grunwald, D., Wilder, S., Kimchi, A., May, E., Lawrence, J. J., May, P. & Oren, M. (1993) Mol. Cell. Biol. 13, 1415-1423.
80. Allday, M. J., Inman, G. J., Crawford, D. H. & Farrell, P. J. (1995) EMBO J. 14, 4994-5005
81. Strasser, A., Harris, A. W., Jacks, T. & Cory, S. (1994) Cell 79, 329-339.
82. Han, Z., Chatterjee, D., He, D. M., Early, J., Pantazis, P., Wyche, J. H. & Hendrickson, E. A. (1995) Mol. Cell. Biol. 15, 5849-5857.
83. Woods, C. M., Zhu, J., McQueney, P. A., Bollag, D. & Lazarides, E. (1995) Mol. Med. 1, 506-526.
84. Mandelkow, E. M. & Mandelkow, E. (1993) Trends Biochem. Sci. 18, 480-483.
85. Morishima-Kawashima, M., Hasegawa, M., Takio, K., Suzuki, M., Yoshida, H., Titani, K. & Ihara, Y. (1995) J. Biol. Chem. 270, 823-829.
86. Lew, J. & Wang, J. H. (1995) Trends Biochem. Sci. 20, 33-37.