Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A

Cancer Cell

Volumn 3, Issue 3, 2003, Pages 247-258

  Sørensen, Claus Storgaard ^a   Syljuåsen, Randi G ^a   Falck, Jacob ^a   Schroeder, Tine ^a   Rönnstrand, Lars ^b   Khanna, Kum Kum ^c   Zhou, Bin Bing ^d   Bartek, Jiri ^a   Lukas, Jiri ^a  

^a DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^b UPPSALA UNIVERSITY   (Sweden)

^c ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^d Experimental Station   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; CHK1 KINASE; CHK2 KINASE; PHOSPHATE; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE PHOSPHATASE; SERINE DERIVATIVE; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; DNA BINDING PROTEIN; PROTEIN KINASE; SERINE; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CANCER CELL CULTURE; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA SYNTHESIS; EMBRYO; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME MECHANISM; ENZYME METABOLISM; ENZYME REGULATION; FEMALE; HUMAN; HUMAN CELL; IONIZING RADIATION; MAMMAL; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RADIOSENSITIVITY; BIOLOGICAL MODEL; CELL CULTURE; CELL CYCLE; DNA REPLICATION; ENZYME ACTIVATION; HELA CELL; KINETICS; METABOLISM; PHOSPHORYLATION; RADIATION EXPOSURE; SIGNAL TRANSDUCTION;

MAMMALIA;

CDC25 PHOSPHATASE; CELL CYCLE; CELL CYCLE PROTEINS; DNA REPLICATION; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HELA CELLS; HUMANS; KINETICS; MODELS, BIOLOGICAL; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RADIATION, IONIZING; S PHASE; SERINE; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0012966157     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1535-6108(03)00048-5     Document Type: Article

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