메뉴 건너뛰기




Volumn 18, Issue 10, 1998, Pages 5992-6000

The locus control region is necessary for gene expression in the human β-globin locus but not the maintenance of an open chromatin structure in erythroid cells

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN;

EID: 0031708415     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.18.10.5992     Document Type: Article
Times cited : (152)

References (74)
  • 2
    • 0030886121 scopus 로고    scopus 로고
    • The activation domain of the enhancer binding protein p45NF-E2 interacts with TAFII130 and mediates long-range activation of the α- and β-globin gene loci in an erythroid cell line
    • Amrolia, P. J., L. Ramamurthy, D. Saluja, N. Tanese, S. M. Jane, and J. M. Cunningham. 1997. The activation domain of the enhancer binding protein p45NF-E2 interacts with TAFII130 and mediates long-range activation of the α- and β-globin gene loci in an erythroid cell line. Proc. Natl. Acad. Sci. USA 94:10051-10056.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10051-10056
    • Amrolia, P.J.1    Ramamurthy, L.2    Saluja, D.3    Tanese, N.4    Jane, S.M.5    Cunningham, J.M.6
  • 3
    • 0030826364 scopus 로고    scopus 로고
    • Intergenic transcription and transinduction of the human β-globin locus
    • Ashe, H. L., J. Monks, M. Wijgerde, P. Fraser, and N. J. Proudfoot. 1997. Intergenic transcription and transinduction of the human β-globin locus. Genes Dev. 11:2494-2509.
    • (1997) Genes Dev. , vol.11 , pp. 2494-2509
    • Ashe, H.L.1    Monks, J.2    Wijgerde, M.3    Fraser, P.4    Proudfoot, N.J.5
  • 4
    • 3543083554 scopus 로고    scopus 로고
    • Unpublished data
    • 3a.Bender, M. Unpublished data.
    • Bender, M.1
  • 6
    • 0029130729 scopus 로고
    • Targeted inactivation of the major positive regulatory element (HS-40) of the human α-globin gene locus
    • Bernet, A., S. Sabatier, D. J. Picketts, R. Ouzana, F. Morlé, D. R. Higgs, and J. Godet. 1995. Targeted inactivation of the major positive regulatory element (HS-40) of the human α-globin gene locus. Blood 86:1202-1211.
    • (1995) Blood , vol.86 , pp. 1202-1211
    • Bernet, A.1    Sabatier, S.2    Picketts, D.J.3    Ouzana, R.4    Morlé, F.5    Higgs, D.R.6    Godet, J.7
  • 7
    • 0024536789 scopus 로고
    • The β-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner
    • Blom van Assendelft, G., O. Hanscombe, F. Grosveld, and D. R. Greaves. 1989. The β-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner. Cell 56:969-977.
    • (1989) Cell , vol.56 , pp. 969-977
    • Van Blom Assendelft, G.1    Hanscombe, O.2    Grosveld, F.3    Greaves, D.R.4
  • 8
    • 0028138645 scopus 로고
    • Dissection of the locus control function located on the chicken lysozyme gene domain in transgenic mice
    • Bonifer, C., N. Yannoutsos, G. Krüger, F. Grosveld, and A. E. Sippel. 1994. Dissection of the locus control function located on the chicken lysozyme gene domain in transgenic mice. Nucleic Acids Res. 22:4202-4210.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 4202-4210
    • Bonifer, C.1    Yannoutsos, N.2    Krüger, G.3    Grosveld, F.4    Sippel, A.E.5
  • 9
    • 0020328412 scopus 로고
    • Beta-globin transcript found in induced erythroleukemia cells is homologous to the beta h0 and beta h1 genes
    • Brown, P. A., R. W. Padgett, S. C. Hardies, C. A. Hutchison III, and M. H. Edgell. 1982. Beta-globin transcript found in induced erythroleukemia cells is homologous to the beta h0 and beta h1 genes. Proc. Natl. Acad. Sci. USA 79:2753-2757.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 2753-2757
    • Brown, P.A.1    Padgett, R.W.2    Hardies, S.C.3    Hutchison III, C.A.4    Edgell, M.H.5
  • 10
    • 0029860719 scopus 로고    scopus 로고
    • Different thermostabilities of FLP and Cre recombinases:implications for applied site-specific recombination
    • 7a.Buchholz, F., L. Ringrose, P. O. Angrand, F. Rossi, and A. F. Stewart. 1996. Different thermostabilities of FLP and Cre recombinases:implications for applied site-specific recombination. Nucleic Acids Res. 24:4256-4262.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4256-4262
    • Buchholz, F.1    Ringrose, L.2    Angrand, P.O.3    Rossi, F.4    Stewart, A.F.5
  • 11
    • 0027254748 scopus 로고
    • A 5′ element of the chicken β-globin domain serves as an insulator in human erythroid cells and protects against position effect in drosophila
    • Chung, J. H., M. Whiteley, and G. Felsenfeld. 1993. A 5′ element of the chicken β-globin domain serves as an insulator in human erythroid cells and protects against position effect in drosophila. Cell 74:505-514.
    • (1993) Cell , vol.74 , pp. 505-514
    • Chung, J.H.1    Whiteley, M.2    Felsenfeld, G.3
  • 12
    • 0025101148 scopus 로고
    • Definition of the minimal requirements within the human β-globin gene and the dominant control region for high level expression
    • Collis, P., M. Antoniou, and F. Grosveid. 1990. Definition of the minimal requirements within the human β-globin gene and the dominant control region for high level expression. EMBO J. 9:233-240.
    • (1990) EMBO J. , vol.9 , pp. 233-240
    • Collis, P.1    Antoniou, M.2    Grosveid, F.3
  • 13
    • 0029013420 scopus 로고
    • Contrasting effects of α and β globin regulatory elements on chromatin structure may be related to their different chromosomal environments
    • Craddock, C. F., P. Vyas, J. A. Sharpe, H. Ayyub, W. G. Wood, and D. R. Higgs. 1995. Contrasting effects of α and β globin regulatory elements on chromatin structure may be related to their different chromosomal environments. EMBO J. 14:1718-1726.
    • (1995) EMBO J. , vol.14 , pp. 1718-1726
    • Craddock, C.F.1    Vyas, P.2    Sharpe, J.A.3    Ayyub, H.4    Wood, W.G.5    Higgs, D.R.6
  • 14
    • 0024433083 scopus 로고
    • Human β-globin gene expression in transgenic mice is enhanced by a distant DNaseI hypersensitive site
    • Curtin, P. T., D. Liu, W. Liu, J. C. Chang, and Y. W. Kan. 1989. Human β-globin gene expression in transgenic mice is enhanced by a distant DNaseI hypersensitive site. Proc. Natl. Acad. Sci. USA 86:7082-7086.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 7082-7086
    • Curtin, P.T.1    Liu, D.2    Liu, W.3    Chang, J.C.4    Kan, Y.W.5
  • 15
    • 0025370230 scopus 로고
    • Erythroid-specific nuclease-hypersensitive sites flanking the human β-globin domain
    • Dhar, V., A. Nandi, C. L. Schildkraut, and A. I. Skoultchi. 1990. Erythroid-specific nuclease-hypersensitive sites flanking the human β-globin domain. Mol. Cell. Biol. 10:4324-4333.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 4324-4333
    • Dhar, V.1    Nandi, A.2    Schildkraut, C.L.3    Skoultchi, A.I.4
  • 16
    • 0030050208 scopus 로고    scopus 로고
    • Efficient modification of human chromosomal alleles using recombination-proficient chicken/human microcell hybrids
    • Dieken, E. S., E. M. Epner, S. Fiering, R. E. K. Fournier, and M. Groudine. 1996. Efficient modification of human chromosomal alleles using recombination-proficient chicken/human microcell hybrids. Nat. Genet. 12:174-182.
    • (1996) Nat. Genet. , vol.12 , pp. 174-182
    • Dieken, E.S.1    Epner, E.M.2    Fiering, S.3    Fournier, R.E.K.4    Groudine, M.5
  • 17
    • 3543127930 scopus 로고    scopus 로고
    • Unpublished data
    • 13a.Epner, E. Unpublished data.
    • Epner, E.1
  • 20
    • 0027305095 scopus 로고
    • An "in-out" strategy using gene targeting and FLP recombinase for the functional dissection of complex DNA regulatory elements:analysis of the 7beta;-globin locus control region
    • Fiering, S., C. G. Kim, E. M. Epner, and M. Groudine. 1993. An "in-out" strategy using gene targeting and FLP recombinase for the functional dissection of complex DNA regulatory elements:analysis of the 7beta;-globin locus control region. Proc. Natl. Acad. Sci. USA 90:8469-8473.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8469-8473
    • Fiering, S.1    Kim, C.G.2    Epner, E.M.3    Groudine, M.4
  • 21
    • 0029091902 scopus 로고
    • Targeted deletion of 5′HS2 of the murine β-globin LCR reveals that it is not essential for proper regulation of the β-globin locus
    • Fiering, S., E. Epner, K. Robinson, Y. Zhuang, A. Telling, M. Hu, D. I. K. Martin, T. Enver, T. J. Ley, and M. Groudine. 1995. Targeted deletion of 5′HS2 of the murine β-globin LCR reveals that it is not essential for proper regulation of the β-globin locus. Genes Dev. 9:2203-2213.
    • (1995) Genes Dev. , vol.9 , pp. 2203-2213
    • Fiering, S.1    Epner, E.2    Robinson, K.3    Zhuang, Y.4    Telling, A.5    Hu, M.6    Martin, D.I.K.7    Enver, T.8    Ley, T.J.9    Groudine, M.10
  • 22
    • 0023550898 scopus 로고
    • Evidence for a locus activation region:the formation of developmentally stable hypersensitive sites in globin-expressing hybrids
    • Forrester, W. C., S. Takegawa, T. Papayannopoulou, G. Stamatoyannopoulos, and M. Groudine. 1987. Evidence for a locus activation region:the formation of developmentally stable hypersensitive sites in globin-expressing hybrids. Nucleic Acids Res. 15:10159-10177.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 10159-10177
    • Forrester, W.C.1    Takegawa, S.2    Papayannopoulou, T.3    Stamatoyannopoulos, G.4    Groudine, M.5
  • 24
    • 0025107556 scopus 로고
    • A deletion of the human β-globin locus activation region causes a major alteration in chromatin structure and replication across the entire β-globin locus
    • Forrester, W. C., E. Epner, M. C. Driscoll, T. Enver, M. Brice, T. Papayannopoulou, and M. Groudine. 1990. A deletion of the human β-globin locus activation region causes a major alteration in chromatin structure and replication across the entire β-globin locus. Genes Dev. 4:1637-1649.
    • (1990) Genes Dev. , vol.4 , pp. 1637-1649
    • Forrester, W.C.1    Epner, E.2    Driscoll, M.C.3    Enver, T.4    Brice, M.5    Papayannopoulou, T.6    Groudine, M.7
  • 25
    • 0025369610 scopus 로고
    • DNasel hypersensitive site 1, 2, and 3 of the human β-globin dominant control region direct position-independent expression
    • Fraser, P., J. Hurst, P. Collis, and F. Grosveld. 1990. DNasel hypersensitive site 1, 2, and 3 of the human β-globin dominant control region direct position-independent expression. Nucleic Acids Res. 18:3503-3508.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 3503-3508
    • Fraser, P.1    Hurst, J.2    Collis, P.3    Grosveld, F.4
  • 26
    • 0027417886 scopus 로고
    • Each hypersensitive site of the human β-globin locus control region confers a different developmental pattern of expression on the globin genes
    • Fraser, P., S. Pruzina, M. Antoniou, and F. Grosveld. 1993. Each hypersensitive site of the human β-globin locus control region confers a different developmental pattern of expression on the globin genes. Genes Dev. 7:106-113.
    • (1993) Genes Dev. , vol.7 , pp. 106-113
    • Fraser, P.1    Pruzina, S.2    Antoniou, M.3    Grosveld, F.4
  • 27
    • 0030458054 scopus 로고    scopus 로고
    • Variegated expression of a globin transgene correlates with chromatin accessibility but not methylation status
    • Garrick, D., H. Sutherland, G. Robertson, and E. Whitelaw. 1996. Variegated expression of a globin transgene correlates with chromatin accessibility but not methylation status. Nucleic Acids Res. 24:4902-4909.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4902-4909
    • Garrick, D.1    Sutherland, H.2    Robertson, G.3    Whitelaw, E.4
  • 28
    • 0030922269 scopus 로고    scopus 로고
    • The role of insulator elements in defining domains of gene expression
    • Geyer, P. K. 1997. The role of insulator elements in defining domains of gene expression. Curr. Opin. Genet. Dev. 7:242-248.
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 242-248
    • Geyer, P.K.1
  • 29
    • 0022388399 scopus 로고
    • Determination of DNA sequences essential for FLP-mediated recombination by a novel method
    • Gronostajski, R. M., and R. D. Sadowski. 1985. Determination of DNA sequences essential for FLP-mediated recombination by a novel method. J. Biol. Chem. 260:12320-12327.
    • (1985) J. Biol. Chem. , vol.260 , pp. 12320-12327
    • Gronostajski, R.M.1    Sadowski, R.D.2
  • 30
    • 0024291350 scopus 로고
    • Stable propagation of the active transcriptional state of an immunoglobulin μ gene requires continuous enhancer function
    • Grosschedl, R., and M. Marx. 1988. Stable propagation of the active transcriptional state of an immunoglobulin μ gene requires continuous enhancer function. Cell 55:645-654.
    • (1988) Cell , vol.55 , pp. 645-654
    • Grosschedl, R.1    Marx, M.2
  • 31
    • 0023663887 scopus 로고
    • Position-independent, high-level expression of the human β-globin gene in transgenic mice
    • Grosveld, F., G. Blom van Assendelft, D. R. Greaves, and G. Kollias. 1987. Position-independent, high-level expression of the human β-globin gene in transgenic mice. Cell 51:975-985.
    • (1987) Cell , vol.51 , pp. 975-985
    • Grosveld, F.1    Van Blom Assendelft, G.2    Greaves, D.R.3    Kollias, G.4
  • 32
    • 0027280936 scopus 로고
    • Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting
    • Gu, H., Y. R. Zou, and K. Rajewsky. 1993. Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting. Cell 73:1155-1164.
    • (1993) Cell , vol.73 , pp. 1155-1164
    • Gu, H.1    Zou, Y.R.2    Rajewsky, K.3
  • 33
    • 0028326787 scopus 로고
    • Core histone hyperacetylation co-maps with generalized DNaseI sensitivity in the chicken β-globin chromosomal domain
    • Hebbes, T. R., A. L. Clayton, A. W. Thorne, and C. Crane-Robinson. 1994. Core histone hyperacetylation co-maps with generalized DNaseI sensitivity in the chicken β-globin chromosomal domain. EMBO J. 13:1823-1830.
    • (1994) EMBO J. , vol.13 , pp. 1823-1830
    • Hebbes, T.R.1    Clayton, A.L.2    Thorne, A.W.3    Crane-Robinson, C.4
  • 35
    • 0026453360 scopus 로고
    • Structure and function of the murine β-globin locus control region 5′ HS-3
    • Hug, B. A., A. M. Moon, and T. J. Ley. 1992. Structure and function of the murine β-globin locus control region 5′ HS-3. Nucleic Acids Res. 20:5771-5778.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 5771-5778
    • Hug, B.A.1    Moon, A.M.2    Ley, T.J.3
  • 36
    • 0029954767 scopus 로고    scopus 로고
    • Analysis of mice containing a targeted deletion of beta-globin locus control region 5′ hypersensitive site 3
    • Hug, B. A., R. L. Wesselschmidt, S. Fiering, M. A. Bender, E. Epner, M. Groudine, and T. J. Ley. 1996. Analysis of mice containing a targeted deletion of beta-globin locus control region 5′ hypersensitive site 3. Mol. Cell. Biol. 16:2906-2912.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2906-2912
    • Hug, B.A.1    Wesselschmidt, R.L.2    Fiering, S.3    Bender, M.A.4    Epner, E.5    Groudine, M.6    Ley, T.J.7
  • 37
    • 17544371344 scopus 로고    scopus 로고
    • Role of DNA sequences outside the cores of DNase hypersensitive sites (HSs) in functions of the β-globin locus control region
    • Jackson, J. D., H. Petrykowska, S. Philipsen, W. Miller, and R. Hardison. 1996. Role of DNA sequences outside the cores of DNase hypersensitive sites (HSs) in functions of the β-globin locus control region. J. Biol. Chem. 271:11871-11878.
    • (1996) J. Biol. Chem. , vol.271 , pp. 11871-11878
    • Jackson, J.D.1    Petrykowska, H.2    Philipsen, S.3    Miller, W.4    Hardison, R.5
  • 38
    • 0024114856 scopus 로고
    • Nuclear scaffold attachment sites in the human globin gene complexes
    • Jarman, A. P., and D. R. Higgs. 1988. Nuclear scaffold attachment sites in the human globin gene complexes. EMBO J. 7:3337-3344.
    • (1988) EMBO J. , vol.7 , pp. 3337-3344
    • Jarman, A.P.1    Higgs, D.R.2
  • 39
    • 0026704374 scopus 로고
    • Inactivation of the human β-globin gene by targeted insertion into the β-globin locus control region
    • Kim, C. G., E. M. Epner, W. C. Forrester, and M. Groudine. 1992. Inactivation of the human β-globin gene by targeted insertion into the β-globin locus control region. Genes Dev. 6:928-938.
    • (1992) Genes Dev. , vol.6 , pp. 928-938
    • Kim, C.G.1    Epner, E.M.2    Forrester, W.C.3    Groudine, M.4
  • 40
    • 0030726908 scopus 로고    scopus 로고
    • Locus control regions:overcoming heterochromatin-induced gene inactivation in mammals
    • Kioussis, D., and R. Festenstein. 1997. Locus control regions:overcoming heterochromatin-induced gene inactivation in mammals. Curr. Opin. Genet. Dev. 7:614-619.
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 614-619
    • Kioussis, D.1    Festenstein, R.2
  • 41
    • 0027749608 scopus 로고
    • Replication structure of the human beta-globin gene domain
    • Kitsberg, D., S. Selig, I. Keshet, and H. Cedar. 1993. Replication structure of the human beta-globin gene domain. Nature 366:588-590.
    • (1993) Nature , vol.366 , pp. 588-590
    • Kitsberg, D.1    Selig, S.2    Keshet, I.3    Cedar, H.4
  • 42
    • 0026058715 scopus 로고
    • The proximal element of the β-globin locus control region is not functionally required in vivo
    • Kulozik, A. E., S. Bail, A. Bellan-Koch, C. R. Bartrann, E. Kohne, and E. Kleihauer. 1991. The proximal element of the β-globin locus control region is not functionally required in vivo. J. Clin. Invest. 87:2142-2146.
    • (1991) J. Clin. Invest. , vol.87 , pp. 2142-2146
    • Kulozik, A.E.1    Bail, S.2    Bellan-Koch, A.3    Bartrann, C.R.4    Kohne, E.5    Kleihauer, E.6
  • 43
    • 0024710956 scopus 로고
    • Physical mapping of human chromosome 17 using fragment-containing microcell hybrids
    • Leach, R. J., M. J. Thayer, A. J. Schafer, and R. E. K. Fournier. 1989. Physical mapping of human chromosome 17 using fragment-containing microcell hybrids. Genomics 5:167-176.
    • (1989) Genomics , vol.5 , pp. 167-176
    • Leach, R.J.1    Thayer, M.J.2    Schafer, A.J.3    Fournier, R.E.K.4
  • 44
    • 0027998844 scopus 로고
    • Hypersensitive site 5 of the human β locus control region functions as a chromatin insulator
    • Li, Q., and G. Stamatoyannopoulos. 1994. Hypersensitive site 5 of the human β locus control region functions as a chromatin insulator. Blood 84:1399-1401.
    • (1994) Blood , vol.84 , pp. 1399-1401
    • Li, Q.1    Stamatoyannopoulos, G.2
  • 45
    • 0025128991 scopus 로고
    • High-resolution mapping of human chromosome 11 by in situ hybridization with cosmid clones
    • Lichter, P., C.-J. C. Tang, K. Call, G. Hermanson, G. A. Evans, D. Housman, and D. C. Ward. 1990. High-resolution mapping of human chromosome 11 by in situ hybridization with cosmid clones. Science 247:64-69.
    • (1990) Science , vol.247 , pp. 64-69
    • Lichter, P.1    Tang, C.-J.C.2    Call, K.3    Hermanson, G.4    Evans, G.A.5    Housman, D.6    Ward, D.C.7
  • 46
    • 0026516460 scopus 로고
    • Dissection of the enhancer activity of β-globin 5′ DNaseI-hypersensitive site 2 in transgenic mice
    • Liu, D., J. C. Chang, P. Moi, W. Liu, Y. W. Kan, and P. T. Curtin. 1992. Dissection of the enhancer activity of β-globin 5′ DNaseI-hypersensitive site 2 in transgenic mice. Proc. Natl. Acad. Sci. USA 89:3899-3903.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 3899-3903
    • Liu, D.1    Chang, J.C.2    Moi, P.3    Liu, W.4    Kan, Y.W.5    Curtin, P.T.6
  • 47
    • 0030219342 scopus 로고    scopus 로고
    • Regulation of beta-globin gene expression. Straightening out the locus
    • Martin, D., S. Fiering, and M. Groudine. 1996. Regulation of beta-globin gene expression. Straightening out the locus. Curr. Opin. Genet. Dev. 6:488-495.
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 488-495
    • Martin, D.1    Fiering, S.2    Groudine, M.3
  • 49
    • 0025242796 scopus 로고
    • Synergistic enhancement of globin gene expression by activator protein-1-like proteins
    • Moi, P., and Y. W. Kan. 1990. Synergistic enhancement of globin gene expression by activator protein-1-like proteins. Proc. Natl. Acad. Sci. USA 87:9000-9004.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9000-9004
    • Moi, P.1    Kan, Y.W.2
  • 50
    • 11944256454 scopus 로고
    • Conservation of the primary structure, organization, and function of the human and mouse β-globin locus activation regions
    • Moon, A. M., and T. J. Ley. 1990. Conservation of the primary structure, organization, and function of the human and mouse β-globin locus activation regions. Proc. Natl. Acad. Sci. USA 87:7693-7697.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 7693-7697
    • Moon, A.M.1    Ley, T.J.2
  • 51
    • 0025779046 scopus 로고
    • Functional properties of the β-globin locus control region in K562 crythroleukemia cells
    • Moon, A. M., and T. J. Ley. 1991. Functional properties of the β-globin locus control region in K562 crythroleukemia cells. Blood 77:2272-2284.
    • (1991) Blood , vol.77 , pp. 2272-2284
    • Moon, A.M.1    Ley, T.J.2
  • 52
    • 0025291510 scopus 로고
    • Tandem AP-1-binding sites within the human β-globin dominant control region functions as an inducible enhancer in erythroid cells
    • Ney, P. A., B. P. Sorrentino, K. T. MeDonagh, and A. W. Nienhuis. 1990. Tandem AP-1-binding sites within the human β-globin dominant control region functions as an inducible enhancer in erythroid cells. Genes Dev. 4:993-1006.
    • (1990) Genes Dev. , vol.4 , pp. 993-1006
    • Ney, P.A.1    Sorrentino, B.P.2    MeDonagh, K.T.3    Nienhuis, A.W.4
  • 53
    • 0030908999 scopus 로고    scopus 로고
    • Expression of the (recombinant) endogenous immunoglobulin heavy-chain locus requires the intronic matrix attachment regions
    • Oancea, A. E., M. Berru, and M. J. Shulman. 1997. Expression of the (recombinant) endogenous immunoglobulin heavy-chain locus requires the intronic matrix attachment regions. Mol. Cell. Biol. 17:2658-2668.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2658-2668
    • Oancea, A.E.1    Berru, M.2    Shulman, M.J.3
  • 54
    • 0025847620 scopus 로고
    • Recombinase-mediated gene activation and site-specific integration in mammalian cells
    • O'Gorman, S., D. T. Fox, and G. M. Wahl. 1991. Recombinase-mediated gene activation and site-specific integration in mammalian cells. Science 251:1351-1355.
    • (1991) Science , vol.251 , pp. 1351-1355
    • O'Gorman, S.1    Fox, D.T.2    Wahl, G.M.3
  • 55
    • 0029119093 scopus 로고
    • Histone H4 acetylation distinguishes coding regions of the human genome from heterochromatin in a differentiation-dependent but transcription-independent manner
    • O'Neill, L. P., and B. M. Turner. 1995. Histone H4 acetylation distinguishes coding regions of the human genome from heterochromatin in a differentiation-dependent but transcription-independent manner. EMBO J. 14:3946-3957.
    • (1995) EMBO J. , vol.14 , pp. 3946-3957
    • O'Neill, L.P.1    Turner, B.M.2
  • 56
    • 0030789734 scopus 로고    scopus 로고
    • Adjacent DNA elements dominantly restrict the ubiquitous activity of a novel chromatin-opening region to specific tissues
    • Ortiz, B. J., D. Cado, V. Chen, P. W. Diaz, and A. Winoto. 1997. Adjacent DNA elements dominantly restrict the ubiquitous activity of a novel chromatin-opening region to specific tissues. EMBO J. 16:5037-5045.
    • (1997) EMBO J. , vol.16 , pp. 5037-5045
    • Ortiz, B.J.1    Cado, D.2    Chen, V.3    Diaz, P.W.4    Winoto, A.5
  • 58
    • 0025815198 scopus 로고
    • Glucocorticoids are required for establishment and maintenance of an alteration in chromatin structure:induction leads to a reversible disruption of nucleosomes over an enhancer
    • Reik, A., G. Schütz, and A. F. Stewart. 1991. Glucocorticoids are required for establishment and maintenance of an alteration in chromatin structure:induction leads to a reversible disruption of nucleosomes over an enhancer. EMBO J. 10:2569-2576.
    • (1991) EMBO J. , vol.10 , pp. 2569-2576
    • Reik, A.1    Schütz, G.2    Stewart, A.F.3
  • 59
    • 0027174299 scopus 로고
    • An enhancer/locus control region is not sufficient to open chromatin
    • Reitman, M., E. Lee, H. Westphal, and G. Felsenfeld. 1993. An enhancer/locus control region is not sufficient to open chromatin. Mol. Cell. Biol. 13:3990-3998.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3990-3998
    • Reitman, M.1    Lee, E.2    Westphal, H.3    Felsenfeld, G.4
  • 60
    • 0024635998 scopus 로고
    • A single erythroid-specific DNaseI super-hypersensitive site activates high levels of human β-globin gene expression in transgenic mice
    • Ryan, T. M., R. R. Behringer, N. C. Martin, T. M. Townes, R. D. Palmiter, and R. L. Brinster. 1989. A single erythroid-specific DNaseI super-hypersensitive site activates high levels of human β-globin gene expression in transgenic mice. Genes Dev. 3:314-323.
    • (1989) Genes Dev. , vol.3 , pp. 314-323
    • Ryan, T.M.1    Behringer, R.R.2    Martin, N.C.3    Townes, T.M.4    Palmiter, R.D.5    Brinster, R.L.6
  • 61
    • 0024041732 scopus 로고
    • Site-specific DNA recombination in mammalian cells by CRE recombinase of bacteriophage P1
    • Sauer, B., and N. Henderson. 1988. Site-specific DNA recombination in mammalian cells by CRE recombinase of bacteriophage P1. Proc. Natl. Acad. Sci. USA 85:5166-5170.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 5166-5170
    • Sauer, B.1    Henderson, N.2
  • 62
    • 0022378550 scopus 로고
    • The FLP recombinase of the yeast 2-micron plasmid:characterization of its recombination site
    • Senecoff, J. F., R. C. Bruckner, and M. M. Cox. 1985. The FLP recombinase of the yeast 2-micron plasmid:characterization of its recombination site. Proc. Natl. Acad. Sci. USA 82:7270-7274.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 7270-7274
    • Senecoff, J.F.1    Bruckner, R.C.2    Cox, M.M.3
  • 63
    • 0025304168 scopus 로고
    • A 46 base pair enhancer sequence within the locus activating region is required for induced expression of the γ-globin gene during erythroid development
    • Sorrentino, B., P. Ney, D. Bodine, and A. W. Nienhuis. 1990. A 46 base pair enhancer sequence within the locus activating region is required for induced expression of the γ-globin gene during erythroid development. Nucleic Acids Res. 18:2721-2731.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 2721-2731
    • Sorrentino, B.1    Ney, P.2    Bodine, D.3    Nienhuis, A.W.4
  • 64
    • 0032030770 scopus 로고    scopus 로고
    • Histone acetylation and transcriptional regulatory mechanisms
    • Struhl, K. 1998. Histone acetylation and transcriptional regulatory mechanisms. Genes Dev. 12:599-606.
    • (1998) Genes Dev. , vol.12 , pp. 599-606
    • Struhl, K.1
  • 65
    • 0024506821 scopus 로고
    • A dominant control region from the human β-globin locus conferring integrations site independent gene expression
    • Talbot, D., P. Collis, M. Anotiou, M. Vidal, F. Brosveld, and D. R. Greaves. 1989. A dominant control region from the human β-globin locus conferring integrations site independent gene expression. Nature 338:352-355.
    • (1989) Nature , vol.338 , pp. 352-355
    • Talbot, D.1    Collis, P.2    Anotiou, M.3    Vidal, M.4    Brosveld, F.5    Greaves, D.R.6
  • 66
    • 0344272073 scopus 로고
    • The 'beta-like globin' gene domain in human erythroid cells
    • Tuan, D., W. Solomon, Q. Li, and I. M. London. 1985. The 'beta-like globin' gene domain in human erythroid cells. Proc. Natl. Acad. Sci. USA 82:6384-6388.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 6384-6388
    • Tuan, D.1    Solomon, W.2    Li, Q.3    London, I.M.4
  • 67
    • 0026482145 scopus 로고
    • Transcription of the hypersensitive site HS2 enhancer in erythroid cells
    • Tuan, D., S. Kong, and K. Hu. 1992. Transcription of the hypersensitive site HS2 enhancer in erythroid cells. Proc. Natl. Acad. Sci. USA 89:11219-11223.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 11219-11223
    • Tuan, D.1    Kong, S.2    Hu, K.3
  • 68
    • 0024591610 scopus 로고
    • An erythroid-specific, developmental-stage-independent enhancer far upstream of the human "β-like globin" genes
    • Tuan, D. Y., W. B. Solomon, I. M. London, and D. P. Lee. 1989. An erythroid-specific, developmental-stage-independent enhancer far upstream of the human "β-like globin" genes. Proc. Natl. Acad. Sci. USA 86:2554-2558.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 2554-2558
    • Tuan, D.Y.1    Solomon, W.B.2    London, I.M.3    Lee, D.P.4
  • 72
    • 0009723501 scopus 로고    scopus 로고
    • In situ hybridization to human metaphase chromosomes using DIG-, biotin, or fluorochrome-labeled DNA probes and detection with fluorochrome conjugates
    • Boehringer Mannheim Biochemicals, Indianapolis, Ind.
    • Wiegant, J. 1996. In situ hybridization to human metaphase chromosomes using DIG-, biotin, or fluorochrome-labeled DNA probes and detection with fluorochrome conjugates, p. 62-71. In Nonradioactive in situ hybridization application manual. Boehringer Mannheim Biochemicals, Indianapolis, Ind.
    • (1996) Nonradioactive in Situ Hybridization Application Manual , pp. 62-71
    • Wiegant, J.1
  • 73
    • 0028180340 scopus 로고
    • A 5′ β-globin matrix-attachment region and the polyoma enhancer together confer position-independent transcription
    • Yu, J., J. H. Bock, J. L. Slightom, and B. Villeponteau. 1994. A 5′ β-globin matrix-attachment region and the polyoma enhancer together confer position-independent transcription. Gene 139:139-145.
    • (1994) Gene , vol.139 , pp. 139-145
    • Yu, J.1    Bock, J.H.2    Slightom, J.L.3    Villeponteau, B.4
  • 74
    • 0026079220 scopus 로고
    • Murine erythroleukemia cell line GM979 contains factors that can activate silent chromosomal.human γ-globin genes
    • Zitnik, G., P. Hines, G. Stamatoyannopoulos, and T. Papapyannopoulou. 1991. Murine erythroleukemia cell line GM979 contains factors that can activate silent chromosomal.human γ-globin genes. Proc. Natl. Acad. Sci. USA 88:2530-2534.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 2530-2534
    • Zitnik, G.1    Hines, P.2    Stamatoyannopoulos, G.3    Papapyannopoulou, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.