-
1
-
-
0033612371
-
Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration
-
Seasholtz, T.M., Majumdar, M., Kaplan, D.D., and Brown, J.H. Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration. Circ. Res. 84, 1186-1193 (1999).
-
(1999)
Circ. Res.
, vol.84
, pp. 1186-1193
-
-
Seasholtz, T.M.1
Majumdar, M.2
Kaplan, D.D.3
Brown, J.H.4
-
2
-
-
0033198057
-
Rho-like GTPases: Their role in epithelial cell-cell adhesion and invasion
-
Sander, E.E. and Collard, J.G. Rho-like GTPases: Their role in epithelial cell-cell adhesion and invasion. Eur. J. Cancer 35 1302-1308 (1999).
-
(1999)
Eur. J. Cancer
, vol.35
, pp. 1302-1308
-
-
Sander, E.E.1
Collard, J.G.2
-
3
-
-
0032562675
-
Requirement for Rho-mediated myosin light chain phosphorylation in thrombin-stimulated cell rounding and its dissociation from mitogenesis
-
Majumdar, M., Seasholtz, T.M., Goldstein, D., de Lanerolle, P., and Brown, J.H. Requirement for Rho-mediated myosin light chain phosphorylation in thrombin-stimulated cell rounding and its dissociation from mitogenesis. J. Biol. Chem. 273, 10099-10106 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10099-10106
-
-
Majumdar, M.1
Seasholtz, T.M.2
Goldstein, D.3
de Lanerolle, P.4
Brown, J.H.5
-
4
-
-
0035827716
-
Human urotensin II-induced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho kinase
-
Sauzeau, V., Le Mellionnec, E., Bertoglio, J., Scalbert, E., Pacaud, P., and Loirand, G. Human urotensin II-induced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho kinase. Circ. Res. 88, 1102-1104 (2001).
-
(2001)
Circ. Res.
, vol.88
, pp. 1102-1104
-
-
Sauzeau, V.1
Le Mellionnec, E.2
Bertoglio, J.3
Scalbert, E.4
Pacaud, P.5
Loirand, G.6
-
5
-
-
0032450986
-
Regulation of SRF activity by Rho family GTPases
-
Treisman, R., Alberts, A.S., and Sahai, E. Regulation of SRF activity by Rho family GTPases. Cold Spring Harb. Symp. Quant. Biol. 63, 643-651 (1998).
-
(1998)
Cold Spring Harb. Symp. Quant. Biol.
, vol.63
, pp. 643-651
-
-
Treisman, R.1
Alberts, A.S.2
Sahai, E.3
-
6
-
-
0033946118
-
The Rho effector, PKN, regulates ANF gene transcription in cardiomyocutes through a serum response element
-
Morissette, M. R., Sah, V.P., Glembotski, C.C., and Brown, J.H. The Rho effector, PKN, regulates ANF gene transcription in cardiomyocutes through a serum response element. Am. J. Physiol. 278, H1769-H1774 (2000).
-
(2000)
Am. J. Physiol.
, vol.278
-
-
Morissette, M.R.1
Sah, V.P.2
Glembotski, C.C.3
Brown, J.H.4
-
7
-
-
0035253673
-
Transcriptional activation of the small GTPase gene RhoB by genotoxic stress is regulated via a CCAAT element
-
Fritz, G and Kaina, B. Transcriptional activation of the small GTPase gene RhoB by genotoxic stress is regulated via a CCAAT element. Nucleic Acids Res. 29, 792-798 (2001).
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 792-798
-
-
Fritz, G.1
Kaina, B.2
-
8
-
-
0034674417
-
Both farnesylated and geranylgeranylated RhoB inhibit malignant transformation and suppress human tumor growth in nude mice
-
Chen, Z., Sun, J., Pradines, A., Favre, G., Adnane, J., and Sebti, S.M. Both farnesylated and geranylgeranylated RhoB inhibit malignant transformation and suppress human tumor growth in nude mice. J. Biol. Chem. 275, 17974-17978 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 17974-17978
-
-
Chen, Z.1
Sun, J.2
Pradines, A.3
Favre, G.4
Adnane, J.5
Sebti, S.M.6
-
9
-
-
0031974721
-
Overexpression of the rhoC gene correlates with progression of duodenal adenocarcinoma of the pancreas
-
Suwa, H., Ohshio, G., Imamura, T., Watanabe, G., Arii, S., Imamura, M., Narumiya, S., Hiai, H., and Fukumoto, M. Overexpression of the rhoC gene correlates with progression of duodenal adenocarcinoma of the pancreas. Br. J. Cancer 77, 147-152 (1998).
-
(1998)
Br. J. Cancer
, vol.77
, pp. 147-152
-
-
Suwa, H.1
Ohshio, G.2
Imamura, T.3
Watanabe, G.4
Arii, S.5
Imamura, M.6
Narumiya, S.7
Hiai, H.8
Fukumoto, M.9
-
10
-
-
0032835343
-
A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype
-
van Golen, K.L., Davies, S., Wu, Z.F. et al. A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype. Clin. Cancer Res. 5, 2511-2519 (1999).
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 2511-2519
-
-
van Golen, K.L.1
Davies, S.2
Wu, Z.F.3
-
11
-
-
0033081753
-
Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
-
Ren, X.D., Kiosses, W. B., and Schwartz, M. A. Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J. 18, 578-585 (1999).
-
(1999)
EMBO J.
, vol.18
, pp. 578-585
-
-
Ren, X.D.1
Kiosses, W.B.2
Schwartz, M.A.3
-
12
-
-
0042171820
-
Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system
-
Dubreuil, C. I., Winton, M.J., and McKerracher, L. Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system. J. Cell Biol. 162, 233-243 (2003).
-
(2003)
J. Cell Biol.
, vol.162
, pp. 233-243
-
-
Dubreuil, C.I.1
Winton, M.J.2
McKerracher, L.3
-
13
-
-
0042672950
-
Activity of Rho-family GTPases during cell division as visualized with FRET-based probes
-
Yoshizaki, H., Ohba, Y., Kurokawa, K., Itoh, R.E., Nakamura, T, Mochizuchi, N., Nagashima, K., and Matsuda, M. Activity of Rho-family GTPases during cell division as visualized with FRET-based probes. J. Cell Biol. 162, 223-232 (2003).
-
(2003)
J. Cell Biol.
, vol.162
, pp. 223-232
-
-
Yoshizaki, H.1
Ohba, Y.2
Kurokawa, K.3
Itoh, R.E.4
Nakamura, T.5
Mochizuchi, N.6
Nagashima, K.7
Matsuda, M.8
-
14
-
-
0031826567
-
Bacterial cytotoxins target Rho GTPases
-
Schmidt, G. and Aktories, K. Bacterial cytotoxins target Rho GTPases. Naturwissenschaften 85, 253-261 (1998).
-
(1998)
Naturwissenschaften
, vol.85
, pp. 253-261
-
-
Schmidt, G.1
Aktories, K.2
-
15
-
-
0030610785
-
Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1
-
Schmidt, G., Sehr, P., Wilm, M., Selzer, J., Mann, M., and Aktories, K. Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1. Nature 387, 725-729 (1997).
-
(1997)
Nature
, vol.387
, pp. 725-729
-
-
Schmidt, G.1
Sehr, P.2
Wilm, M.3
Selzer, J.4
Mann, M.5
Aktories, K.6
-
16
-
-
0032867338
-
Identification of the region of Rho involved in substrate recognition by Escherichia coli cytotoxic necrotizing factor 1 (CNF1)
-
Lerm, M., Schmidt, G., Goehring, U. M., Schirmer, J., and Aktories, K. Identification of the region of Rho involved in substrate recognition by Escherichia coli cytotoxic necrotizing factor 1 (CNF1). J. Biol. Chem. 274, 28999-29004 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28999-29004
-
-
Lerm, M.1
Schmidt, G.2
Goehring, U.M.3
Schirmer, J.4
Aktories, K.5
-
17
-
-
2642559507
-
Beyond the laboratory: Clinical implications for statin pleiotropy
-
Halcox, J.P. and Deanfield, J.E. Beyond the laboratory: clinical implications for statin pleiotropy. Circulation 109, 1142-1148 (2004).
-
(2004)
Circulation
, vol.109
, pp. 1142-1148
-
-
Halcox, J.P.1
Deanfield, J.E.2
-
18
-
-
0032508533
-
Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase
-
Laufs, U. and Liao, J.K. Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase. J. Biol. Chem. 273, 24266-24271 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 24266-24271
-
-
Laufs, U.1
Liao, J.K.2
-
19
-
-
8344221885
-
Monitoring the cellular effects of HMG-CoA Reductase Inhibitors in vitro and ex vivo
-
Chica, I., Schneiderhan-Marra, N., Yilmaz, A., Garlichs, C.D., and Goppelt-Struebe, M. Monitoring the cellular effects of HMG-CoA Reductase Inhibitors in vitro and ex vivo. Arterioscler. Thromb. Vasc. Biol. 24, 2046-2050 (2004).
-
(2004)
Arterioscler. Thromb. Vasc. Biol.
, vol.24
, pp. 2046-2050
-
-
Chica, I.1
Schneiderhan-Marra, N.2
Yilmaz, A.3
Garlichs, C.D.4
Goppelt-Struebe, M.5
-
20
-
-
0032567361
-
Phosphorylation of moesin by Rho-associated kinase (Rho-kinase) plays a crucial role in the formation of microvilli-like structures
-
Oshiro, N., Fukata, Y, and Kaibuchi, K. Phosphorylation of moesin by Rho-associated kinase (Rho-kinase) plays a crucial role in the formation of microvilli-like structures. J. Biol. Chem. 273, 34663-34666 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34663-34666
-
-
Oshiro, N.1
Fukata, Y.2
Kaibuchi, K.3
-
21
-
-
0031926623
-
Myosin II activation promotes neurite retraction during the action of Rho and Rho-kinase
-
Amano, M., Chihara, K., Nakamura, N., Fukata, Y., Yano, T., Shibata, M., Ikebe, M., and Kaibuchi, K. Myosin II activation promotes neurite retraction during the action of Rho and Rho-kinase. Genes Cells 3, 177-188 (1998).
-
(1998)
Genes Cells
, vol.3
, pp. 177-188
-
-
Amano, M.1
Chihara, K.2
Nakamura, N.3
Fukata, Y.4
Yano, T.5
Shibata, M.6
Ikebe, M.7
Kaibuchi, K.8
-
25
-
-
9444242736
-
Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
-
Kimura, K., Ito, M., Amano, M.et al. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 273, 245-248 (1996).
-
(1996)
Science
, vol.273
, pp. 245-248
-
-
Kimura, K.1
Ito, M.2
Amano, M.3
-
26
-
-
0030977123
-
Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation
-
Kureishi, Y., Kobayashi, S., Amano, M., Kimura, K., Kanaide, H., Nakano, T., Kaibuchi, K., and Ito, M. Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation. J. Biol. Chem. 272, 12257-12260 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12257-12260
-
-
Kureishi, Y.1
Kobayashi, S.2
Amano, M.3
Kimura, K.4
Kanaide, H.5
Nakano, T.6
Kaibuchi, K.7
Ito, M.8
-
27
-
-
0030656619
-
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
-
Uehata, M., Ishizaki, T., Satoh, H. et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 389, 990-994 (1997).
-
(1997)
Nature
, vol.389
, pp. 990-994
-
-
Uehata, M.1
Ishizaki, T.2
Satoh, H.3
-
29
-
-
0033618378
-
3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing Rho GTPase-induced down-regulation of p27Kip1
-
Laufs, U., Marra, D., Node, K., and Liao, J.K. 3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing Rho GTPase-induced down-regulation of p27Kip1. J. Biol. Chem. 274, 21926-21931 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21926-21931
-
-
Laufs, U.1
Marra, D.2
Node, K.3
Liao, J.K.4
-
31
-
-
0026778133
-
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
-
Ridley, A.J. and Hall, A. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70, 389-399 (1992).
-
(1992)
Cell
, vol.70
, pp. 389-399
-
-
Ridley, A.J.1
Hall, A.2
-
32
-
-
4644248958
-
Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogenesis caused by serotonin
-
Liu, Y., Suzuki, Y.J., Day, R.M., and Fanburg, B. L. Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogenesis caused by serotonin. Circ. Res. 95, 579-586 (2004).
-
(2004)
Circ. Res.
, vol.95
, pp. 579-586
-
-
Liu, Y.1
Suzuki, Y.J.2
Day, R.M.3
Fanburg, B.L.4
-
33
-
-
0042733080
-
Initiation and transduction of stretch-induced RhoA and Rac1 activation through caveolae: Cytoskeletal regulation of ERK translocation
-
Kawamura, S., Miyamoto, S., and Brown, J. H. Initiation and transduction of stretch-induced RhoA and Rac1 activation through caveolae: cytoskeletal regulation of ERK translocation. J. Biol. Chem. 278, 31111-31117 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31111-31117
-
-
Kawamura, S.1
Miyamoto, S.2
Brown, J.H.3
-
34
-
-
0035736485
-
Timing of cyclin D1 expression within G1 phase is controlled by Rho
-
Welsh, C. F., Roovers, K., Villanueva, J., Liu, Y., Schwartz, M. A., and Assoian, R. K. Timing of cyclin D1 expression within G1 phase is controlled by Rho. Nat. Cell Biol. 3, 950-957 (2001).
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 950-957
-
-
Welsh, C.F.1
Roovers, K.2
Villanueva, J.3
Liu, Y.4
Schwartz, M.A.5
Assoian, R.K.6
-
35
-
-
0041440180
-
Nuclear translocation of LIM kinase mediates Rho-Rho kinase regulation of cyclin D1 expression
-
Roovers, K., Klein, E A., Castagnino, P., and Assoian, R.K. Nuclear translocation of LIM kinase mediates Rho-Rho kinase regulation of cyclin D1 expression. Dev. Cell 5, 273-284 (2003).
-
(2003)
Dev. Cell
, vol.5
, pp. 273-284
-
-
Roovers, K.1
Klein, E.A.2
Castagnino, P.3
Assoian, R.K.4
-
36
-
-
0142182734
-
Nitric oxide inhibits stretch-induced MAPK activation in mesangial cells through RhoA inactivation
-
Krepinsky, J.C., Ingram, A.J., Tang, D., Wu, D., Liu, L., and Scholey, J.W. Nitric oxide inhibits stretch-induced MAPK activation in mesangial cells through RhoA inactivation. J. Am. Soc. Nephrol. 14, 2790-2800 (2003).
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, pp. 2790-2800
-
-
Krepinsky, J.C.1
Ingram, A.J.2
Tang, D.3
Wu, D.4
Liu, L.5
Scholey, J.W.6
-
37
-
-
0027244434
-
1-adrenoceptor in tail artery and aorta from spontaneously hypertensive and Wistar-Kyoto rats
-
1-adrenoceptor in tail artery and aorta from spontaneously hypertensive and Wistar-Kyoto rats. J. Cardiovasc. Pharmacol. 22, 191-197 (1993).
-
(1993)
J. Cardiovasc. Pharmacol.
, vol.22
, pp. 191-197
-
-
Vila, E.1
Tabernero, A.2
Ivorra, M.D.3
-
39
-
-
0027969286
-
2+ sensitization of coronary artery contraction in genetically hypertensive rats. Evidence for altered signal transduction in the coronary smooth muscle cells
-
2+ sensitization of coronary artery contraction in genetically hypertensive rats. Evidence for altered signal transduction in the coronary smooth muscle cells. J. Clin. Invest. 94, 1397-1403 (1994).
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 1397-1403
-
-
Satoh, S.1
Kreutz, R.2
Wilm, C.3
Ganten, D.4
Pfitzer, G.5
-
40
-
-
0035957574
-
Evidence that Rho-kinase activity contributes to cerebral vascular tone in vivo and is enhanced during chronic hypertension
-
Chrissolis, S. and Sobey, C.G. Evidence that Rho-kinase activity contributes to cerebral vascular tone in vivo and is enhanced during chronic hypertension. Circ. Res. 88, 774-779 (2001).
-
(2001)
Circ. Res.
, vol.88
, pp. 774-779
-
-
Chrissolis, S.1
Sobey, C.G.2
-
41
-
-
0031951477
-
Migration of vascular smooth muscle cells is enhanced in cultures derived from spontaneously hypertensive rat
-
Hsieh, C.-C. and Lau, Y-T. Migration of vascular smooth muscle cells is enhanced in cultures derived from spontaneously hypertensive rat. Pflugers Arch. 435, 286-292 (1998).
-
(1998)
Pflugers Arch.
, vol.435
, pp. 286-292
-
-
Hsieh, C.-C.1
Lau, Y.-T.2
-
42
-
-
0027364463
-
Effect of hypertension on arterial structure and wound repair at the microvascular anastamosis site using stroke-prone spontaneously hypertensive rats (SHRSP)
-
Isogai, N., Fujii, S., Tsukahara, T., and Kamiishi, H. Effect of hypertension on arterial structure and wound repair at the microvascular anastamosis site using stroke-prone spontaneously hypertensive rats (SHRSP). Microsurgery 14, 501-507 (1993).
-
(1993)
Microsurgery
, vol.14
, pp. 501-507
-
-
Isogai, N.1
Fujii, S.2
Tsukahara, T.3
Kamiishi, H.4
-
43
-
-
0025108592
-
Angiotensin II-induced proliferation of aortic myocytes in spontaneously hypertensive rats
-
Paquet, J.-L., Baudouin-Legros, M., Brunelle, G., and Meyer, P. Angiotensin II-induced proliferation of aortic myocytes in spontaneously hypertensive rats. J. Hypertens. 8, 565-572 (1990).
-
(1990)
J. Hypertens.
, vol.8
, pp. 565-572
-
-
Paquet, J.-L.1
Baudouin-Legros, M.2
Brunelle, G.3
Meyer, P.4
-
44
-
-
0029024607
-
Stimulation of two vascular smooth muscle-derived cell lines by angiotensin II: Differential second messenger responses leading to mitogenesis
-
Morton, C., Baines, R., Masood, I., Ng, L., and Boarder, M.R. Stimulation of two vascular smooth muscle-derived cell lines by angiotensin II: Differential second messenger responses leading to mitogenesis. Br. J. Pharmacol. 115, 361-367 (1995).
-
(1995)
Br. J. Pharmacol.
, vol.115
, pp. 361-367
-
-
Morton, C.1
Baines, R.2
Masood, I.3
Ng, L.4
Boarder, M.R.5
-
45
-
-
0031848223
-
Translating data on anti hypertensive drugs into clinical practice
-
Weber, M.A. Translating data on anti hypertensive drugs into clinical practice. American J. Hypertens. 11, 89S-94S (1998).
-
(1998)
American J. Hypertens.
, vol.11
-
-
Weber, M.A.1
-
46
-
-
0037234525
-
Genetics of blood pressure, hypertensive complications, and antihypertensive drug responses
-
Turner, S.T. and Boerwinkle, E. Genetics of blood pressure, hypertensive complications, and antihypertensive drug responses. Pharmacogenomics. 4, 53-65 (2003).
-
(2003)
Pharmacogenomics
, vol.4
, pp. 53-65
-
-
Turner, S.T.1
Boerwinkle, E.2
-
47
-
-
0036794272
-
Beyond blood pressure: The endothelium and atherosclerosis progression
-
Schiffrin, E. L. Beyond blood pressure: the endothelium and atherosclerosis progression. Am. J. Hypertens. 15, 115S-122S (2002).
-
(2002)
Am. J. Hypertens.
, vol.15
-
-
Schiffrin, E.L.1
-
49
-
-
0037423816
-
Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle
-
Seko, T., Ito, M., Kureishi, Y., Okamoto, R., Moriki, N., Onishi, K., Isaka, N., Hartshorne, D. J., and Nakano, T. Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle. Circ. Res. 92, 411-418 (2003).
-
(2003)
Circ. Res.
, vol.92
, pp. 411-418
-
-
Seko, T.1
Ito, M.2
Kureishi, Y.3
Okamoto, R.4
Moriki, N.5
Onishi, K.6
Isaka, N.7
Hartshorne, D.J.8
Nakano, T.9
-
50
-
-
2342580708
-
RhoA activation in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats
-
Moriki, N., Ito, M., Seko, T. et al. RhoA activation in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats. Hypertens. Res. 27, 263-270 (2004).
-
(2004)
Hypertens. Res.
, vol.27
, pp. 263-270
-
-
Moriki, N.1
Ito, M.2
Seko, T.3
-
51
-
-
0344838338
-
Increased RhoA translocation in renal cortex of diabetic rats
-
Massey, A. R., Miao, L., Smith, B.N., Liu, J., Kusaka, I., Zhang, J.H., and Tang, J. Increased RhoA translocation in renal cortex of diabetic rats. Life Sci. 72, 2943-2952 (2003).
-
(2003)
Life Sci.
, vol.72
, pp. 2943-2952
-
-
Massey, A.R.1
Miao, L.2
Smith, B.N.3
Liu, J.4
Kusaka, I.5
Zhang, J.H.6
Tang, J.7
-
52
-
-
0037178608
-
Upregulation of small GTPase RhoA in the basilar artery from diabetic (mellitus) rats
-
Miao, L., Calvert, J.W., Tang, J., and Zhang, J.H. Upregulation of small GTPase RhoA in the basilar artery from diabetic (mellitus) rats. Life Sci. 71, 1175-1185 (2002).
-
(2002)
Life Sci.
, vol.71
, pp. 1175-1185
-
-
Miao, L.1
Calvert, J.W.2
Tang, J.3
Zhang, J.H.4
-
53
-
-
0021991915
-
Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta
-
Martin, W., Villani, G.M., Jothianandan, D., and Furchgott, R.F. Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta. J. Pharmacol. Exp. Ther. 232, 708-716 (1985).
-
(1985)
J. Pharmacol. Exp. Ther.
, vol.232
, pp. 708-716
-
-
Martin, W.1
Villani, G.M.2
Jothianandan, D.3
Furchgott, R.F.4
-
54
-
-
0023505509
-
Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
-
Ignarro, L. J., Buga, G.M., Wood, K.S., Byrns, R.E., and Chaudhuri, G. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc. Natl. Acad. Sci. U.S.A. 84, 9265-9269 (1987).
-
(1987)
Proc. Natl. Acad. Sci. U.S.A.
, vol.84
, pp. 9265-9269
-
-
Ignarro, L.J.1
Buga, G.M.2
Wood, K.S.3
Byrns, R.E.4
Chaudhuri, G.5
-
55
-
-
0034037024
-
Impaired endothelial function in arterial hypertension and hypercholesterolemia: Potential mechanisms and differences
-
John, S. and Schmieder, R.E. Impaired endothelial function in arterial hypertension and hypercholesterolemia: potential mechanisms and differences. J. Hypertens. 18, 363-374 (2000).
-
(2000)
J. Hypertens.
, vol.18
, pp. 363-374
-
-
John, S.1
Schmieder, R.E.2
-
56
-
-
0031886546
-
Alterations of nitric oxide synthase expression with aging and hypertension in rats
-
Chou, T.C., Yen, M.H., and Li, C.Y. Alterations of nitric oxide synthase expression with aging and hypertension in rats. Hypertension 31, 643-648 (1998).
-
(1998)
Hypertension
, vol.31
, pp. 643-648
-
-
Chou, T.C.1
Yen, M.H.2
Li, C.Y.3
-
57
-
-
0029021148
-
Hypertension in mice lacking the gene for endothelial nitric oxide synthase
-
Huang, P.L., Huang, Z., Mashimo, H., Bloch, K.D., Moskowitz, M.A., Bevan, J.A., and Fishman, M.C. Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 377, 239-242 (1995).
-
(1995)
Nature
, vol.377
, pp. 239-242
-
-
Huang, P.L.1
Huang, Z.2
Mashimo, H.3
Bloch, K.D.4
Moskowitz, M.A.5
Bevan, J.A.6
Fishman, M.C.7
-
58
-
-
0030793748
-
Prolonged reduction of high blood pressure with human nitric oxide synthase gene delivery
-
Lin, K.F., Chao, L., and Chao, J. Prolonged reduction of high blood pressure with human nitric oxide synthase gene delivery. Hypertension 30, 307-313 (1997).
-
(1997)
Hypertension
, vol.30
, pp. 307-313
-
-
Lin, K.F.1
Chao, L.2
Chao, J.3
-
59
-
-
0033664617
-
Fluvastatin upregulates inducible nitric oxide synthase expression in cytokine-stimulated vascular smooth muscle cells
-
Chen, H., Ikeda, U., Shimpo, M., Ikeda, M., Minota, S., and Shimada, K. Fluvastatin upregulates inducible nitric oxide synthase expression in cytokine-stimulated vascular smooth muscle cells. Hypertension 36, 923-928 (2000).
-
(2000)
Hypertension
, vol.36
, pp. 923-928
-
-
Chen, H.1
Ikeda, U.2
Shimpo, M.3
Ikeda, M.4
Minota, S.5
Shimada, K.6
-
60
-
-
0033935251
-
Inhibition of Rho protein stimulates iNOS expression in rat vascular smooth muscle cells
-
Muniyappa, R., Xu, R., Ram, J.L, and Sowers, J.R. Inhibition of Rho protein stimulates iNOS expression in rat vascular smooth muscle cells. Am. J. Physiol. 278, H1762-H1768 (2000).
-
(2000)
Am. J. Physiol.
, vol.278
-
-
Muniyappa, R.1
Xu, R.2
Ram, J.L.3
Sowers, J.R.4
-
61
-
-
5344268785
-
Inhibition of Rho-kinase leads to a rapid activation of phosphatidylinositol 3-kinase/protein kinase Akt and cardiovascular protection
-
Wolfrum, S., Dendorfer, A., Rikitake, Y., Stalker, T.J., Gong, Y., Scalia, R., Dominiak, P., and Lioa, J.K. Inhibition of Rho-kinase leads to a rapid activation of phosphatidylinositol 3-kinase/protein kinase Akt and cardiovascular protection. Arteroslcer. Thromb. Vasc. Biol. 24, 1842-1847 (2004).
-
(2004)
Arteroslcer. Thromb. Vasc. Biol.
, vol.24
, pp. 1842-1847
-
-
Wolfrum, S.1
Dendorfer, A.2
Rikitake, Y.3
Stalker, T.J.4
Gong, Y.5
Scalia, R.6
Dominiak, P.7
Lioa, J.K.8
-
62
-
-
0034810237
-
CGMP-dependent protein kinase phosphorylates and inactivates RhoA
-
Sawada, N., Itoh, H., Yamashita, J. et al. cGMP-dependent protein kinase phosphorylates and inactivates RhoA. Biochem. Biophys. Res. Commun. 280, 798-805 (2001).
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.280
, pp. 798-805
-
-
Sawada, N.1
Itoh, H.2
Yamashita, J.3
-
63
-
-
0033624157
-
Role for G12/G13 in agonist-imduce vascular smooth muscle cell contraction
-
Gohla, A., Schultz, G., and Offermanns, S. Role for G12/G13 in agonist-imduce vascular smooth muscle cell contraction. Circ. Res. 87, 221-227 (2000).
-
(2000)
Circ. Res.
, vol.87
, pp. 221-227
-
-
Gohla, A.1
Schultz, G.2
Offermanns, S.3
-
64
-
-
0034647534
-
2+ sensitization of contraction in vascular smooth muscle
-
2+ sensitization of contraction in vascular smooth muscle. J. Biol. Chem. 275, 21722-21729 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 21722-21729
-
-
Sauzeau, V.1
Le Jeune, H.2
Cario-Toumaniantz, C.3
Smolenski, A.4
Lohmann, S.M.5
Bertoglio, J.6
Chardin, P.7
Pacaud, P.8
Loirand, G.9
-
65
-
-
0037020262
-
CGMP-dependent protein kinase inhibits serum-response element-dependent transcription by inhibiting rho activation and functions
-
Gudi, T., Chen, J.C., Casteel, D.E., Seasholtz, T.M., Boss, G.R., and Pilz, R.B. cGMP-dependent protein kinase inhibits serum-response element-dependent transcription by inhibiting rho activation and functions. J. Biol. Chem. 277, 37382-37393 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 37382-37393
-
-
Gudi, T.1
Chen, J.C.2
Casteel, D.E.3
Seasholtz, T.M.4
Boss, G.R.5
Pilz, R.B.6
-
66
-
-
3042521592
-
Nitric oxide and arterial disease
-
Barbato, J. E. and Tzeng, E. Nitric oxide and arterial disease. J. Vasc. Surg. 40, 187-193 (2004).
-
(2004)
J. Vasc. Surg.
, vol.40
, pp. 187-193
-
-
Barbato, J.E.1
Tzeng, E.2
-
67
-
-
1942536531
-
Anti-vascular cell adhesion molecule-1 and anti-very late antigen-4 monoclonal antibodies inhibit neointimal hyperplasia in the murine model of arterial injury
-
Suzuki, J., Izawa, A., and Isobe, M. Anti-vascular cell adhesion molecule-1 and anti-very late antigen-4 monoclonal antibodies inhibit neointimal hyperplasia in the murine model of arterial injury. Acta. Cardiol. 59, 147-152 (2004).
-
(2004)
Acta Cardiol.
, vol.59
, pp. 147-152
-
-
Suzuki, J.1
Izawa, A.2
Isobe, M.3
-
68
-
-
0033584398
-
The kinase inhibitor fasudil (HA-1077) reduces intimal hyperplasia through inhibiting migration and enhancing cell loss of vascular smooth muscle cells
-
Negoro, N., Hoshiga, M., Seto, M. et al. The kinase inhibitor fasudil (HA-1077) reduces intimal hyperplasia through inhibiting migration and enhancing cell loss of vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 262, 211-215 (1999).
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.262
, pp. 211-215
-
-
Negoro, N.1
Hoshiga, M.2
Seto, M.3
-
69
-
-
0342314481
-
Inhibition of Rho-associated kinase results in suppression of neointimal formation of balloon-injured arteries
-
Sawada, N., Itoh, H., Ueyama, K. et al. Inhibition of Rho-associated kinase results in suppression of neointimal formation of balloon-injured arteries. Circulation 101, 2030-2033 (2000 ).
-
(2000)
Circulation
, vol.101
, pp. 2030-2033
-
-
Sawada, N.1
Itoh, H.2
Ueyama, K.3
-
70
-
-
0035895335
-
Role of Rho-Associated Kinase in Neointima Formation After Vascular Injury
-
Shibata, R., Kai, H., Seki, Y., Kato, S., Morimatsu, M., Kaibuchi, K., and Imaizumi, T. Role of Rho-Associated Kinase in Neointima Formation After Vascular Injury. Circulation 103, 284-289 (2001).
-
(2001)
Circulation
, vol.103
, pp. 284-289
-
-
Shibata, R.1
Kai, H.2
Seki, Y.3
Kato, S.4
Morimatsu, M.5
Kaibuchi, K.6
Imaizumi, T.7
-
71
-
-
9144227431
-
Long-term inhibition of Rho-kinase suppresses neointimal formation after stent implantation in porcine coronary arteries: Involvement of multiple mechanisms
-
Matsumoto, Y., Uwatoku, T., Oi, K. et al. Long-term inhibition of Rho-kinase suppresses neointimal formation after stent implantation in porcine coronary arteries: Involvement of multiple mechanisms. Arterioscler. Thromb. Vasc. Biol. 24, 181-186 (2004).
-
(2004)
Arterioscler. Thromb. Vasc. Biol.
, vol.24
, pp. 181-186
-
-
Matsumoto, Y.1
Uwatoku, T.2
Oi, K.3
-
72
-
-
12944289797
-
Gene transfer of dominant negative Rho kinase suppresses neointimal formation after balloon injury in pigs
-
Eto, Y., Shimokawa, H., Hiroki, J. et al. Gene transfer of dominant negative Rho kinase suppresses neointimal formation after balloon injury in pigs. Am. J. Physiol. Heart. Circ. Physiol. 278, H1744-H1750 (2000).
-
(2000)
Am. J. Physiol. Heart. Circ. Physiol.
, vol.278
-
-
Eto, Y.1
Shimokawa, H.2
Hiroki, J.3
-
73
-
-
0242266962
-
Rho-associated protein kinase contributes to early atherosclerotic lesion formation in mice
-
Mallat, Z., Gojova, A., Sauzeau, V. Rho-associated protein kinase contributes to early atherosclerotic lesion formation in mice. Circ. Res. 93, 884-888 (2003).
-
(2003)
Circ. Res.
, vol.93
, pp. 884-888
-
-
Mallat, Z.1
Gojova, A.2
Sauzeau, V.3
-
74
-
-
18244401416
-
Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats
-
Kataoka, C., Egashira, K., Inoue, S. Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats. Hypertension 39, 245-250 (2002).
-
(2002)
Hypertension
, vol.39
, pp. 245-250
-
-
Kataoka, C.1
Egashira, K.2
Inoue, S.3
-
75
-
-
0042830245
-
Effects of atorvastatin on in-stent stenosis in normo- and hypercholesterolemic rabbits
-
Herdeg, C., Fitzke, M., Oberhoff, M., Baumbach, A., Schroeder, S., and Karsch, K.R. Effects of atorvastatin on in-stent stenosis in normo- and hypercholesterolemic rabbits. Int. J. Cardiol. 91, 59-69 (2003).
-
(2003)
Int. J. Cardiol.
, vol.91
, pp. 59-69
-
-
Herdeg, C.1
Fitzke, M.2
Oberhoff, M.3
Baumbach, A.4
Schroeder, S.5
Karsch, K.R.6
-
76
-
-
0035980169
-
Antiinflammatory and antiarteriosclerotic actions of HMG-CoA reductase inhibitors in a rat model of chronic inhibition of nitric oxide synthesis
-
Ni, W., Egashira, K., Kataoka, C., Kitamoto, S., Koyanagi, M., Inoue, S., and Takeshita, A. Antiinflammatory and antiarteriosclerotic actions of HMG-CoA reductase inhibitors in a rat model of chronic inhibition of nitric oxide synthesis. Circ. Res. 89 , 415-421 (2001).
-
(2001)
Circ. Res.
, vol.89
, pp. 415-421
-
-
Ni, W.1
Egashira, K.2
Kataoka, C.3
Kitamoto, S.4
Koyanagi, M.5
Inoue, S.6
Takeshita, A.7
-
77
-
-
0035805607
-
Physical and functional interactions of Gaq with Rho and its exchange factors
-
Sagi, S.A., Seasholtz, T.M., Kobiashvilla, M., Wilson, B.A., Toksoz, D., and Brown, J.H. Physical and functional interactions of Gaq with Rho and its exchange factors. J. Biol. Chem. 276, 15445-15452 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 15445-15452
-
-
Sagi, S.A.1
Seasholtz, T.M.2
Kobiashvilla, M.3
Wilson, B.A.4
Toksoz, D.5
Brown, J.H.6
-
78
-
-
5444236527
-
Rho-mediated cytoskeletal rearrangement in response to LPA is functionally antagonized by Rac1 and PIP2
-
Seasholtz, T.M., Radeff-Huang, J., Sagi, S.A., Matteo, R.G., Weems, J.M., Stoudt, A., Buckmaster, C., Feramisco, J., and Brown, J.H. Rho-mediated cytoskeletal rearrangement in response to LPA is functionally antagonized by Rac1 and PIP2. J. Neurochem. 91, 501-12 (2004).
-
(2004)
J. Neurochem.
, vol.91
, pp. 501-512
-
-
Seasholtz, T.M.1
Radeff-Huang, J.2
Sagi, S.A.3
Matteo, R.G.4
Weems, J.M.5
Stoudt, A.6
Buckmaster, C.7
Feramisco, J.8
Brown, J.H.9
-
79
-
-
0032568868
-
3
-
3. Science 280, 2112-2114 (1998).
-
(1998)
Science
, vol.280
, pp. 2112-2114
-
-
Hart, M.J.1
Jiang, X.2
Kozasa, T.3
Roscoe, W.4
Singer, W.D.5
Gilman, A.G.6
Sternweis, P.C.7
Bollag, G.8
-
80
-
-
0033605294
-
A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho
-
Fukuhara, S., Murga, C., Zohar, M., Igishi, T., and Gutkind, J.S. A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho. J. Biol. Chem. 274, 5868-5879 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 5868-5879
-
-
Fukuhara, S.1
Murga, C.2
Zohar, M.3
Igishi, T.4
Gutkind, J.S.5
-
82
-
-
0034597743
-
Activation of RhoA by association of Galpha(13) with Dbl
-
Jin, S. and Exton, J. H. Activation of RhoA by association of Galpha(13) with Dbl. Biochem. Biophys. Res. Commun. 277, 718-721 (2000).
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.277
, pp. 718-721
-
-
Jin, S.1
Exton, J.H.2
-
84
-
-
0142180272
-
Rho inhibition decreases TNF-induced endothelial MAPK activation and monolayer permeability
-
Nwariaku, F.E., Rothenbach, P., Liu, Z., Zhu, X., Turnage, R.H., and Terada, L.S. Rho inhibition decreases TNF-induced endothelial MAPK activation and monolayer permeability. J. Appl. Physiol. 95 1889-1895 (2003).
-
(2003)
J. Appl. Physiol.
, vol.95
, pp. 1889-1895
-
-
Nwariaku, F.E.1
Rothenbach, P.2
Liu, Z.3
Zhu, X.4
Turnage, R.H.5
Terada, L.S.6
-
85
-
-
1342289577
-
Lovastatin inhibits Rho-regulated expression of E-selectin by TNFalpha and attenuates tumor cell adhesion
-
Nubel, T., Dippold, W., Kleinert, H., Kaina, B., and Fritz, G. Lovastatin inhibits Rho-regulated expression of E-selectin by TNFalpha and attenuates tumor cell adhesion. FASEB J. 18, 140-142 (2004).
-
(2004)
FASEB J.
, vol.18
, pp. 140-142
-
-
Nubel, T.1
Dippold, W.2
Kleinert, H.3
Kaina, B.4
Fritz, G.5
-
86
-
-
0033607517
-
Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells
-
Xia, P., Wang, L., Gamble, J.R., and Vadas, M.A. Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells. J. Biol. Chem. 274, 34499-34505 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34499-34505
-
-
Xia, P.1
Wang, L.2
Gamble, J.R.3
Vadas, M.A.4
-
87
-
-
4744347186
-
Sphringosine kinase-1 mediates TNF-α-induced MCP-1 gene expression in endothelial cells: Upregulation by oscillatory flow
-
Chen, X.-L., Grey, J.Y., Thomas, S., Qui, F.-H., Medford, R.M., Wasserman, M.A., and Kunsch, C. Sphringosine kinase-1 mediates TNF-α-induced MCP-1 gene expression in endothelial cells: upregulation by oscillatory flow. Am. J. Physiol. 287, H1452-H1458 (2004).
-
(2004)
Am. J. Physiol.
, vol.287
-
-
Chen, X.-L.1
Grey, J.Y.2
Thomas, S.3
Qui, F.-H.4
Medford, R.M.5
Wasserman, M.A.6
Kunsch, C.7
-
88
-
-
0032702311
-
The IL-1 receptor and Rho directly associate to drive cell activation in inflammation
-
Singh, R., Wang, B., Shirvaikar, A., Khan, S., Kamat, S., Schelling, J.R., Konieczkowski, M., and Sedor, J.R. The IL-1 receptor and Rho directly associate to drive cell activation in inflammation. J. Clin. Invest. 103, 1561-1570 (1999).
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 1561-1570
-
-
Singh, R.1
Wang, B.2
Shirvaikar, A.3
Khan, S.4
Kamat, S.5
Schelling, J.R.6
Konieczkowski, M.7
Sedor, J.R.8
-
89
-
-
1642407666
-
Interleukin-1beta induces a reactive astroglial phenotype via deactivation of the Rho GTPase-Rock axis
-
John, G.R., Chen, L., Rivieccio, M.A., Melendez-Vasquez, C.V., Hartley, A., and Brosnan, C.F. Interleukin-1beta induces a reactive astroglial phenotype via deactivation of the Rho GTPase-Rock axis. J. Neurosci. 24, 2837-2845 (2004).
-
(2004)
J. Neurosci.
, vol.24
, pp. 2837-2845
-
-
John, G.R.1
Chen, L.2
Rivieccio, M.A.3
Melendez-Vasquez, C.V.4
Hartley, A.5
Brosnan, C.F.6
-
90
-
-
0037449723
-
Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells
-
Miller, Y.I., Viriyakosol, S., Binder, C.J., Feramisco, J. R., Kirkland, T.N., and Witztum, J.L. Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells. J. Biol. Chem. 278, 1561-1568 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1561-1568
-
-
Miller, Y.I.1
Viriyakosol, S.2
Binder, C.J.3
Feramisco, J.R.4
Kirkland, T.N.5
Witztum, J.L.6
-
91
-
-
0033618381
-
Role of sphingosine 1-phosphate in the mitogenesis induced by oxidized low density lipoprotein in smooth muscle cells via activation of sphingomyelinase, ceramidase, and sphingosine kinase
-
Auge, N., Nikolova-Karakashian, M., Carpentier, S., Parthasarathy, S., Negre-Salvayre, A., Salvayre, R., Merrill, A. H., Jr., and Levade, T. Role of sphingosine 1-phosphate in the mitogenesis induced by oxidized low density lipoprotein in smooth muscle cells via activation of sphingomyelinase, ceramidase, and sphingosine kinase. J. Biol. Chem. 274, 21533-21538 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21533-21538
-
-
Auge, N.1
Nikolova-Karakashian, M.2
Carpentier, S.3
Parthasarathy, S.4
Negre-Salvayre, A.5
Salvayre, R.6
Merrill Jr., A.H.7
Levade, T.8
-
92
-
-
2942545972
-
Statins prevent oxidized low-density lipoprotein- And lysophosphatidylcholine-induced proliferation of human endothelial cells
-
Schaefer, C.A., Kuhlmann, C.R., Gast, C. et al. Statins prevent oxidized low-density lipoprotein- and lysophosphatidylcholine-induced proliferation of human endothelial cells. Vascul. Pharmacol. 41, 67-73 (2004).
-
(2004)
Vascul. Pharmacol.
, vol.41
, pp. 67-73
-
-
Schaefer, C.A.1
Kuhlmann, C.R.2
Gast, C.3
-
93
-
-
0037498501
-
Oxidized LDL and its compound lysophosphatidylcholine potentiate AngII-induced vasoconstriction by stimulation of RhoA
-
Galle, J., Mameghani, A., Bolz, S.S. et al. Oxidized LDL and its compound lysophosphatidylcholine potentiate AngII-induced vasoconstriction by stimulation of RhoA. J. Am. Soc. Nephrol. 14 1471-1479 (2003).
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, pp. 1471-1479
-
-
Galle, J.1
Mameghani, A.2
Bolz, S.S.3
-
94
-
-
0037120943
-
Glycoxidized low-density lipoprotein downregulates endothelial nitricoxide synthase in human coronary cells
-
Napoli, C., Lerman, L.O., de Nigris, F., Loscalzo, J., and Ignarro, L.J. Glycoxidized low-density lipoprotein downregulates endothelial nitricoxide synthase in human coronary cells. J. Am. Coll. Cardiol. 40, 1515-1522 (2002).
-
(2002)
J. Am. Coll. Cardiol.
, vol.40
, pp. 1515-1522
-
-
Napoli, C.1
Lerman, L.O.2
de Nigris, F.3
Loscalzo, J.4
Ignarro, L.J.5
-
95
-
-
0033536049
-
Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions
-
Siess, W., Zangl, K. J., Essler, M., Bauer, M., Brandl, R., Corrinth, C., Bittman, R., Tigyi, G., and Aepfelbacher, M. Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions. Proc. Natl. Acad. Sci. U.S.A. 96, 6931-6936 (1999).
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 6931-6936
-
-
Siess, W.1
Zangl, K.J.2
Essler, M.3
Bauer, M.4
Brandl, R.5
Corrinth, C.6
Bittman, R.7
Tigyi, G.8
Aepfelbacher, M.9
-
96
-
-
0036920110
-
Oxidized LDL-induced smooth muscle cell proliferation involves the EGF receptor/PI-3 kinase/Akt and the sphingolipid signaling pathways
-
Auge, N., Garcia, V., Maupas-Schwalm, F., Levade, T., Salvayre, R., and Negre-Salvayre, A. Oxidized LDL-induced smooth muscle cell proliferation involves the EGF receptor/PI-3 kinase/Akt and the sphingolipid signaling pathways. Arterioscler. Thromb. Vasc. Bio.l 22, 1990-1995 (2002).
-
(2002)
Arterioscler. Thromb. Vasc. Biol.
, vol.22
, pp. 1990-1995
-
-
Auge, N.1
Garcia, V.2
Maupas-Schwalm, F.3
Levade, T.4
Salvayre, R.5
Negre-Salvayre, A.6
-
97
-
-
0029741690
-
The sphingomyelin-ceramide signaling pathway is involved in oxidized low density lipoprotein-induced cell proliferation
-
Auge, N., Andrieu, N., Negre-Salvayre, A., Thiers, J.C., Levade, T., and Salvayre, R. The sphingomyelin-ceramide signaling pathway is involved in oxidized low density lipoprotein-induced cell proliferation. J. Biol. Chem. 271, 19251-19255 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19251-19255
-
-
Auge, N.1
Andrieu, N.2
Negre-Salvayre, A.3
Thiers, J.C.4
Levade, T.5
Salvayre, R.6
-
99
-
-
0036009909
-
NFkappaB-dependent signaling pathways
-
Li, X. and Stark, G. R. NFkappaB-dependent signaling pathways. Exp. Hematol. 30, 285-296 (2002).
-
(2002)
Exp. Hematol.
, vol.30
, pp. 285-296
-
-
Li, X.1
Stark, G.R.2
-
100
-
-
0032520791
-
Role of the Rho GTPase in bradykinin-stimulated Nuclear Factor-kB activation and IL-1β gene expression in cultured human epithelial cells
-
Pan, Z.K., Ye, R.D., Christiansen, S.C., Jagels, M.A., Bokoch, G.M., and Zuraw, B.L. Role of the Rho GTPase in bradykinin-stimulated Nuclear Factor-kB activation and IL-1β gene expression in cultured human epithelial cells. J. Immunol. 160 3038-3045 (1998).
-
(1998)
J. Immunol.
, vol.160
, pp. 3038-3045
-
-
Pan, Z.K.1
Ye, R.D.2
Christiansen, S.C.3
Jagels, M.A.4
Bokoch, G.M.5
Zuraw, B.L.6
-
101
-
-
0035966092
-
Sphingosine 1-phosphate activates nuclear factor-kappa B through Edg receptors. Activation through Edg-3 and Edg-5, but not Edg-1, in human embryonic kidney 293 cells
-
Siehler, S., Wang, Y., Fan, X., Windh, R. T., and Manning, D. R. Sphingosine 1-phosphate activates nuclear factor-kappa B through Edg receptors. Activation through Edg-3 and Edg-5, but not Edg-1, in human embryonic kidney 293 cells. J. Biol. Chem. 276, 48733-48739 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48733-48739
-
-
Siehler, S.1
Wang, Y.2
Fan, X.3
Windh, R.T.4
Manning, D.R.5
-
102
-
-
0035824511
-
Constitutive activation of NF-kappa B and secretion of interleukin-8 induced by the G protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus involve G alpha(13) and RhoA
-
Shepard, L.W., Yang, M., Xie, P., Browning, D.D., Voyno-Yasenetskaya, T., Kozasa, T., and Ye, R.D. Constitutive activation of NF-kappa B and secretion of interleukin-8 induced by the G protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus involve G alpha(13) and RhoA. J. Biol. Chem. 276, 45979-45987 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 45979-45987
-
-
Shepard, L.W.1
Yang, M.2
Xie, P.3
Browning, D.D.4
Voyno-Yasenetskaya, T.5
Kozasa, T.6
Ye, R.D.7
-
103
-
-
2642556197
-
RhoA and Rac1 signals in fMLP-induced NF-kappaB activation in human blood monocytes
-
Chen, L.Y., Ptasznik, A., and Pan, Z.K. RhoA and Rac1 signals in fMLP-induced NF-kappaB activation in human blood monocytes. Biochem. Biophys. Res. Commun. 319, 629-635 (2004).
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.319
, pp. 629-635
-
-
Chen, L.Y.1
Ptasznik, A.2
Pan, Z.K.3
-
104
-
-
1342346547
-
A Rho exchange factor mediates fMet-Leu-Phe-induced NF-kappaB activation in human peripheral blood monocytes
-
Chen, L.Y., Zuraw, B.L., Ye, R.D., and Pan, Z.K. A Rho exchange factor mediates fMet-Leu-Phe-induced NF-kappaB activation in human peripheral blood monocytes. J. Biol. Chem. 279, 7208-7212 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 7208-7212
-
-
Chen, L.Y.1
Zuraw, B.L.2
Ye, R.D.3
Pan, Z.K.4
-
105
-
-
0036709884
-
Reduction of tumor necrosis factor-alpha (TNF-alpha) related nuclear factor-kappaB (NF-kappaB) translocation but not inhibitor kappa-B (Ikappa-B)-degradation by Rho protein inhibition in human endothelial cells
-
Hippenstiel, S., Schmeck, B., Seybold, J., Krull, M., Eichel-Streiber, C., and Suttorp, N. Reduction of tumor necrosis factor-alpha (TNF-alpha) related nuclear factor-kappaB (NF-kappaB) translocation but not inhibitor kappa-B (Ikappa-B)-degradation by Rho protein inhibition in human endothelial cells. Biochem. Pharmacol. 64, 971-977 (2002).
-
(2002)
Biochem. Pharmacol.
, vol.64
, pp. 971-977
-
-
Hippenstiel, S.1
Schmeck, B.2
Seybold, J.3
Krull, M.4
Eichel-Streiber, C.5
Suttorp, N.6
-
106
-
-
0037960269
-
Rho kinase blockade prevents inflammation via nuclear factor kappa B inhibition: Evidence in Crohn's disease and experimental colitis
-
Segain, J.P., Raingeard, d. I.B., Sauzeau, V. et al. Rho kinase blockade prevents inflammation via nuclear factor kappa B inhibition: Evidence in Crohn's disease and experimental colitis. Gastroenterology 124, 1180-1187 (2003).
-
(2003)
Gastroenterology
, vol.124
, pp. 1180-1187
-
-
Segain, J.P.1
Raingeard, I.B.2
Sauzeau, V.3
-
107
-
-
0036024969
-
An IkappaB-alpha mutant inhibits cytokine gene expression and proliferation in human vascular smooth muscle cells
-
Wang, Z., Castresana, M.R., Detmer, K., and Newman, W.H. An IkappaB-alpha mutant inhibits cytokine gene expression and proliferation in human vascular smooth muscle cells. J. Surg. Res. 102, 198-206 (2002).
-
(2002)
J. Surg. Res.
, vol.102
, pp. 198-206
-
-
Wang, Z.1
Castresana, M.R.2
Detmer, K.3
Newman, W.H.4
-
108
-
-
0141988931
-
Overexpression of mutated IkappaBalpha inhibits vascular smooth muscle cell proliferation and intimal hyperplasia formation
-
Zuckerbraun, B.S., McCloskey, C.A., Mahidhara, R.S., Kim, P.K., Taylor, B.S., and Tzeng, E. Overexpression of mutated IkappaBalpha inhibits vascular smooth muscle cell proliferation and intimal hyperplasia formation. J. Vasc. Surg. 38, 812-819 (2003).
-
(2003)
J. Vasc. Surg.
, vol.38
, pp. 812-819
-
-
Zuckerbraun, B.S.1
McCloskey, C.A.2
Mahidhara, R.S.3
Kim, P.K.4
Taylor, B.S.5
Tzeng, E.6
|