Role for G12/G13 in agonist-induced vascular smooth muscle cell contraction

Circulation Research

Volumn 87, Issue 3, 2000, Pages 221-227

  Gohla, Antje ^a,c   Schultz, Günter ^a   Offermanns, Stefan ^a,b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

G proteins; Myosin light chain phosphorylation; Rho kinase; Smooth muscle; Vasocontractors

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; MYOSIN LIGHT CHAIN; PHOSPHOTRANSFERASE; RHO KINASE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MYOSIN LIGHT CHAIN KINASE; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE; RHO-ASSOCIATED KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SIGNAL PEPTIDE; VASOCONSTRICTOR AGENT;

AGONIST; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SMOOTH MUSCLE CONTRACTION; VASCULAR SMOOTH MUSCLE; ANIMAL; BIOLOGICAL MODEL; CALCIUM SIGNALING; CATTLE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; VASOCONSTRICTION;

ANIMALS; CALCIUM SIGNALING; CATTLE; ENDOTHELIN-1; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HETEROTRIMERIC GTP-BINDING PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, BIOLOGICAL; MUSCLE, SMOOTH, VASCULAR; MYOSIN LIGHT CHAINS; MYOSIN-LIGHT-CHAIN KINASE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RECEPTOR, ENDOTHELIN A; RECEPTORS, ENDOTHELIN; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

EID: 0033624157     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.87.3.221     Document Type: Article

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