Sphingosine kinase-1 mediates TNF-α-induced MCP-1 gene expression in endothelial cells: Upregulation by oscillatory flow

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 287, Issue 4 56-4, 2004, Pages

  Chen, Xi Lin ^a,b   Grey, Janice Y ^a   Thomas, Suzanne ^a   Qiu, Fei Hua ^a   Medford, Russell M ^a   Wasserman, Martin A ^a   Kunsch, Charles ^a  

^a Discovery Research   (United States)

^b AtheroGenics Inc   (United States)

Author keywords

p38 MAPK

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; SMALL INTERFERING RNA; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE KINASE; SPHINGOSINE KINASE 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; LAMINAR FLOW; OSCILLATION; PRIORITY JOURNAL; PROTEIN SECRETION; SHEAR STRESS; UPREGULATION;

ANTINEOPLASTIC AGENTS; AORTA; ARTERIOSCLEROSIS; CELLS, CULTURED; CHEMOKINE CCL2; ENDOTHELIUM, VASCULAR; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROMOTER REGIONS (GENETICS); RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STRESS, MECHANICAL; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 4744347186     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.01101.2003     Document Type: Article

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