Antioxidants in myocardial ischemia-reperfusion injury: Therapeutic potential and basic mechanisms

Archives of Biochemistry and Biophysics

Volumn 420, Issue 2, 2003, Pages 222-236

  Marczin, Nándor ^a   El Habashi, Nihal ^a,b   Hoare, Ginette S ^a   Bundy, Ruth E ^a   Yacoub, Magdi ^a  

^a HAREFIELD HOSPITAL   (United Kingdom)

^b ALEXANDRIA UNIVERSITY   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALLOPURINOL; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CATALASE; CELL PROTEIN; COPPER ZINC SUPEROXIDE DISMUTASE; DEHYDROASCORBIC ACID; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE SYNTHASE; NUCLEIC ACID; REACTIVE OXYGEN METABOLITE; STREPTOKINASE; SUPEROXIDE DISMUTASE;

ADAPTATION; ANTIOXIDANT ACTIVITY; CELL ACTIVATION; CELL SURVIVAL; CLINICAL TRIAL; DRUG ACTIVITY; DRUG MECHANISM; ENZYME ACTIVITY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HUMAN; MITOCHONDRION; MOLECULAR INTERACTION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; REPERFUSION INJURY; SHORT SURVEY; SIGNAL TRANSDUCTION;

ANIMALIA; EUKARYOTA; TRIXIS;

EID: 0344925139     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.abb.2003.08.037     Document Type: Review

References (165)

1. Szent-Gyorgyi A. Proc. Natl. Acad. Sci. USA. 58:1967;2012-2014.
2. Pohl H.A., Gascoyne P.R., Szent-Gyorgyi A. Proc. Natl. Acad. Sci. USA. 74:1977;1558-1560.
3. Szent-Gyorgyi A. Physiol. Chem. Phys. 12:1980;99-110.
4. Suzuki Y., Yamazaki N., Ogawa K., Mizutani K., Kakizawa N. Recent. Adv. Stud. Cardiac. Struct. Metab. 11:1976;599-603.
5. Kramer J.H., Arroyo C.M., Dickens B.F., Weglicki W.B. Free Radic. Biol. Med. 3:1987;153-159.
6. Garlick P.B., Davies M.J., Hearse D.J., Slater T.F. Circ. Res. 61:1987;757-760.
7. Zweier J.L., Flaherty J.T., Weisfeldt M.L. Proc. Natl. Acad. Sci. USA. 84:1987;1404-1407.
8. Haddad J.J. Cell Signal. 14:2002;879-897.
9. Sarkar D., Vallance P., Harding S.E. Eur. J. Heart Fail. 3:2001;527-534.
10. Kojda G., Harrison D. Cardiovasc. Res. 43:1999;562-571.
11. Martin K.R., Barrett J.C. Hum. Exp. Toxicol. 21:2002;71-75.
12. Tsai J.C., Jain M., Hsieh C.M., Lee W.S., Yoshizumi M., Patterson C., Perrella M.A., Cooke C., Wang H., Haber E., Schlegel R., Lee M.E. J. Biol. Chem. 271:1996;3667-3670.
13. Beg A.A., Sha W.C., Bronson R.T., Ghosh S., Baltimore D. Nature. 376:1995;167-170.
14. Davies K.J. IUBMB Life. 50:2000;279-289.
15. Bishopric N.H., Andreka P., Slepak T., Webster K.A. Curr. Opin. Pharmacol. 1:2001;141-150.
16. Moskowitz R., Kukin M. Congest Heart Fail. 5:1999;153-163.
17. Sharma R., Coats A.J., Anker S.D. Int. J. Cardiol. 72:2000;175-186.
18. Kloner R.A., Jennings R.B. Circulation. 104:2001;3158-3167.
19. Hearse D.J. Cardiovasc. Drugs Ther. 5(Suppl. 2):1991;225-235.
20. Poltronieri R., Cevese A., Sbarbati A. Cardioscience. 3:1992;155-160.
21. Gross G.J., Farber N.E., Hardman H.F., Warltier D.C. Am. J. Physiol. 250:1986;H372-H377.
22. Opie L.H. Circulation. 80:1989;1049-1062.
23. Goldhaber J.I., Weiss J.N. Hypertension. 20:1992;118-127.
24. Kukreja R.C., Janin Y. J. Thromb. Thrombolysis. 4:1997;7-24.
25. Bolli R. Cardiovasc. Drugs Ther. 5(Suppl. 2):1991;249-268.
26. Kloner R.A., Przyklenk K., Whittaker P. Circulation. 80:1989;1115-1127.
27. Godin D.V., Garnett M.E. Can. J. Cardiol. 5:1989;365-371.
28. Chatham J.C., Seymour A.L., Harmsen E., Radda G.K. Cardiovasc. Res. 22:1988;833-839.
29. Leichtweis S., Ji L.L. Acta Physiol. Scand. 172:2001;1-10.
30. Pyles L.A., Fortney J.E., Kudlak J.J., Gustafson R.A., Einzig S. J. Thorac. Cardiovasc. Surg. 110:1995;165-171.
31. Pietri S., Culcasi M., Stella L., Cozzone P.J. Eur. J. Biochem. 193:1990;845-854.
32. Ko K.M., Garnett M.E., Godin D.V. Can. J. Cardiol. 6:1990;299-304.
33. Nishinaka Y., Sugiyama S., Yokota M., Saito H., Ozawa T. Heart Vessels. 7:1992;18-23.
34. Alberola A., Such L., Gil F., Zaragoza R., Morcillo E.J. Naunyn Schmiedebergs Arch. Pharmacol. 343:1991;505-510.
35. Steare S.E., Yellon D.M. J. Mol. Cell. Cardiol. 27:1995;65-74.
36. Ho Y.S., Magnenat J.L., Gargano M., Cao J. Environ. Health Perspect. 106(Suppl. 5):1998;1219-1228.
37. Li G., Chen Y., Saari J.T., Kang Y.J. Am. J. Physiol. 273:1997;H1090-H1095.
38. Asimakis G.K., Lick S., Patterson C. Circulation. 105:2002;981-986.
39. Yoshida T., Maulik N., Engelman R.M., Ho Y.S., Das D.K. Circ. Res. 86:2000;264-269.
40. Wang P., Chen H., Qin H., Sankarapandi S., Becher M.W., Wong P.C., Zweier J.L. Proc. Natl. Acad. Sci. USA. 95:1998;4556-4560.
41. Chen E.P., Bittner H.B., Davis R.D., Van Trigt P., Folz R.J. J. Thorac. Cardiovasc. Surg. 115:1998;450-458.
42. Chen E.P., Bittner H.B., Davis R.D., Folz R.J., Van Trigt P. Circulation. 94:1996;II412-II417.
43. Das D.K., Dillmann W., Ho Y.S., Lin K.M., Gloss B.R. Methods Enzymol. 353:2002;346-365.
44. Sharp B.R., Jones S.P., Rimmer D.M., Lefer D.J. Am. J. Physiol. Heart Circ. Physiol. 282:2002;H2422-H2426.
45. Jones S.P., Hoffmeyer M.R., Sharp B.R., Ho Y.S., Lefer D.J. Am. J. Physiol. Heart Circ. Physiol. 284:2003;H277-H282.
46. Dhalla N.S., Elmoselhi A.B., Hata T., Makino N. Cardiovasc. Res. 47:2000;446-456.
47. Ytrehus K. Pharmacol. Res. 42:2000;193-203.
48. Packer J.E., Slater T.F., Willson R.L. Nature. 278:1979;737-738.
49. Kang Y.J. Proc. Soc. Exp. Biol. Med. 222:1999;263-273.
50. Haramaki N., Stewart D.B., Aggarwal S., Ikeda H., Reznick A.Z., Packer L. Free Radic. Biol. Med. 25:1998;329-339.
51. Leedle R.A., Aust S.D. Lipids. 25:1990;241-245.
52. Vergely C., Perrin C., Laubriet A., Oudot A., Zeller M., Guilland J.C., Rochette L. Cardiovasc. Res. 51:2001;89-99.
53. Paraidathathu T., Palamanda J., Kehrer J.P. Toxicology. 90:1994;103-114.
54. Marchant C.T., Barron D.M., Wilson S.M., Jordan L.R., Willis R.J. Basic Res. Cardiol. 88:1993;314-320.
55. Barsacchi R., Coassin M., Maiorino M., Pelosi G., Simonelli C., Ursini F. Free Radic. Biol. Med. 6:1989;573-579.
56. Connaughton M., Kelly F.J., Haddock P.S., Hearse D.J., Shattock M.J. J. Mol. Cell. Cardiol. 28:1996;679-688.
57. Verbunt R.J., Van Dockum W.G., Bastiaanse E.M., Egas J.M., Van der L.A. Mol. Cell. Biochem. 156:1996;79-85.
58. Pucheu S., Coudray C., Tresallet N., Favier A., de Leiris J. J. Mol. Cell. Cardiol. 27:1995;2303-2314.
59. Mezzetti A., Lapenna D., Pierdomenico S.D., Di Giammarco G., Bosco G., Di Ilio C., Santarelli P., Calafiore A.M., Cuccurullo F. J. Card Surg. 8:1993;167-171.
60. Barsacchi R., Pelosi G., Maffei S., Baroni M., Salvatore L., Ursini F., Verunelli F., Biagini A. Int. J. Cardiol. 37:1992;339-343.
61. England M.D., Cavarocchi N.C., O'Brien J.F., Solis E., Pluth J.R., Orszulak T.A., Kaye M.P., Schaff H.V. Circulation. 74:1986;III134-III137.
62. Coghlan J.G., Flitter W.D., Clutton S.M., Panda R., Daly R., Wright G., Ilsley C.D., Slater T.F. J. Thorac. Cardiovasc. Surg. 107:1994;248-256.
63. Coghlan J.G., Flitter W.D., Clutton S.M., Ilsley C.D., Rees A., Slater T.F. J. Thorac. Cardiovasc. Surg. 106:1993;268-274.
64. Pantke U., Volk T., Schmutzler M., Kox W.J., Sitte N., Grune T. Free Radic. Biol. Med. 27:1999;1080-1086.
65. De Vecchi E., Pala M.G., Di Credico G., Agape V., Paolini G., Bonini P.A., Grossi A., Paroni R. Heart. 79:1998;242-247.
66. Starkopf J., Zilmer K., Vihalemm T., Kullisaar T., Zilmer M., Samarutel J. Scand. J. Thorac. Cardiovasc. Surg. 29:1995;181-186.
67. Ferrari R., Ceconi C., Curello S., Alfieri O., Visioli O. Eur. Heart J. 14(Suppl.):1993;G25-G30.
68. Ferrari R., Alfieri O., Curello S., Ceconi C., Cargnoni A., Marzollo P., Pardini A., Caradonna E., Visioli O. Circulation. 81:1990;201-211.
69. Ballmer P.E., Reinhart W.H., Jordan P., Buhler E., Moser U.K., Gey K.F. J. Thorac. Cardiovasc. Surg. 108:1994;311-320.
70. Tangney C.C., Hankins J.S., Murtaugh M.A., Piccione W. Jr. J. Am. Coll. Nutr. 17:1998;162-170.
71. Buffon A., Santini S.A., Ramazzotti V., Rigattieri S., Liuzzo G., Biasucci L.M., Crea F., Giardina B., Maseri A. J. Am. Coll. Cardiol. 35:2000;633-639.
72. Rigattieri S., Buffon A., Ramazzotti V., Mordente A., Crea F., Maseri A., Giardina B., Santini S.A. Ital. Heart J. 1:2000;68-72.
73. Tomasetti M., Alleva R., Piva R., Pancrazi A., Solenghi M.D., Mucaj A., Littarru G.P. Ital. Heart J. 1:2000;216-220.
74. Westhuyzen J., Cochrane A.D., Tesar P.J., Mau T., Cross D.B., Frenneaux M.P., Khafagi F.A., Fleming S.J. J. Thorac. Cardiovasc. Surg. 113:1997;942-948.
75. Demirag K., Askar F.Z., Uyar M., Cevik A., Ozmen D., Mutaf I., Bayindir O. Middle East J. Anesthesiol. 16:2001;67-79.
76. Barta E., Pechan I., Cornak V., Luknarova O., Rendekova V., Verchovodko P. Bratisl. Lek. Listy. 92:1991;174-183.
77. C.C. Li, Zhonghua. Wai. Ke. Za. Zhi. (1990) 2816.
78. Dingchao H., Zhiduan Q., Liye H., Xiaodong F. Thorac. Cardiovasc. Surg. 42:1994;276-278.
79. Mickle D.A., Weisel R.D., Burton G.W., Ingold K.U. Cardiovasc. Drugs Ther. 5(Suppl. 2):1991;309-312.
80. Yau T.M., Weisel R.D., Mickle D.A., Burton G.W., Ingold K.U., Ivanov J., Mohabeer M.K., Tumiati L., Carson S. J. Thorac. Cardiovasc. Surg. 108:1994;302-310.
81. Sisto T., Paajanen H., Metsa-Ketela T., Harmoinen A., Nordback I., Tarkka M. Ann. Thorac. Surg. 59:1995;1519-1523.
82. Lassnigg A., Punz A., Barker R., Keznickl P., Manhart N., Roth E., Hiesmayr M. Br. J. Anaesth. 90:2003;148-154.
83. Ferrari R., Ceconi C., Curello S., Cargnoni A., Alfieri O., Pardini A., Marzollo P., Visioli O. Am. J. Med. 91:1991;95S-105S.
84. Arstall M.A., Yang J., Stafford I., Betts W.H., Horowitz J.D. Circulation. 92:1995;2855-2862.
85. Sochman J. J. Am. Coll. Cardiol. 39:2002;1422-1428.
86. Fink M.P. Curr. Opin. Crit. Care. 8:2002;6-11.
87. Freisleben H.J. Clin. Hemorheol. Microcirc. 23:2000;219-224.
88. Hung L.M., Chen J.K., Lee R.S., Liang H.C., Su M.J. Free Radic. Biol. Med. 30:2001;877-883.
89. Masini E., Cuzzocrea S., Mazzon E., Marzocca C., Mannaioni P.F., Salvemini D. Br. J. Pharmacol. 136:2002;905-917.
90. Gao F., Yao C.L., Gao E., Mo Q.Z., Yan W.L., McLaughlin R., Lopez B.L., Christopher T.A., Ma X.L. J. Pharmacol. Exp. Ther. 301:2002;543-550.
91. Rioufol G., Pietri S., Culcasi M., Loufoua J., Staat P., Pop C., Drieu K., Ovize M. Basic Res. Cardiol. 98:2003;59-68.
92. Sagach V.F., Scrosati M., Fielding J., Rossoni G., Galli C., Visioli F. Pharmacol. Res. 45:2002;435-439.
93. Cui J., Tosaki A., Cordis G.A., Bertelli A.A., Bertelli A., Maulik N., Das D.K. Ann. N.Y. Acad. Sci. 957:2002;308-316.
94. Sato M., Maulik N., Das D.K. Ann. N.Y. Acad. Sci. 957:2002;122-135.
95. Pataki T., Bak I., Kovacs P., Bagchi D., Das D.K., Tosaki A. Am. J. Clin. Nutr. 75:2002;894-899.
96. Chen H., Li D., Saldeen T., Romeo F., Mehta J.L. Biochem. Biophys. Res. Commun. 291:2002;349-353.
97. Koufaki M., Calogeropoulou T., Detsi A., Roditis A., Kourounakis A.P., Papazafiri P., Tsiakitzis K., Gaitanaki C., Beis I., Kourounakis P.N. J. Med. Chem. 44:2001;4300-4303.
98. Sato M., Bagchi D., Tosaki A., Das D.K. Free Radic. Biol. Med. 31:2001;729-737.
99. Lefer D.J., Granger D.N. Am. J. Med. 109:2000;315-323.
100. Chen Z., Siu B., Ho Y.S., Vincent R., Chua C.C., Hamdy R.C., Chua B.H. J. Mol. Cell. Cardiol. 30:1998;2281-2289.
101. Suzuki K., Sawa Y., Ichikawa H., Kaneda Y., Matsuda H. Ann. Thorac. Surg. 68:1999;1266-1271.
102. Abunasra H.J., Smolenski R.T., Morrison K., Yap J., Sheppard M.N., O'Brien T., Suzuki K., Jayakumar J., Yacoub M.H. Eur. J. Cardiothorac. Surg. 20:2001;153-158.
103. Baxter G.F., Yellon D.M. Basic Res. Cardiol. 98:2003;133-136.
104. Beckman J.S., Beckman T.W., Chen J., Marshall P.A., Freeman B.A. Proc. Natl. Acad. Sci. USA. 87:1990;1620-1624.
105. Freeman B.A., Gutierrez H., Rubbo H. Am. J. Physiol. 268:1995;L697-L698.
106. Gilad E., Zingarelli B., Salzman A.L., Szabo C. J. Mol. Cell. Cardiol. 29:1997;2585-2597.
107. Xie Y.W., Wolin M.S. Circulation. 94:1996;2580-2586.
108. Cassina A., Radi R. Arch. Biochem. Biophys. 328:1996;309-316.
109. Radi R., Rodriguez M., Castro L., Telleri R. Arch. Biochem. Biophys. 308:1994;89-95.
110. Cassina A.M., Hodara R., Souza J.M., Thomson L., Castro L., Ischiropoulos H., Freeman B.A., Radi R. J. Biol. Chem. 275:2000;21409-21415.
111. Macmillan-Crow L.A., Cruthirds D.L. Free Radic. Res. 34:2001;325-336.
112. Suzuki K., Murtuza B., Sammut I.A., Latif N., Jayakumar J., Smolenski R.T., Kaneda Y., Sawa Y., Matsuda H., Yacoub M.H. Circulation. 106:2002;I270-I276.
113. Haddad J.J., Land S.C. Br. J. Pharmacol. 135:2002;520-536.
114. Das D.K. Antioxid. Redox Signal. 3:2001;23-37.
115. Maulik N., Sasaki H., Addya S., Das D.K. FEBS Lett. 485:2000;7-12.
116. Barnes P.J., Karin M. N. Engl. J. Med. 336:1997;1066-1071.
117. Ghosh S., Karin M. Cell. 109(Suppl.):2002;S81-S96.
118. Karin M., Lin A. Nat. Immunol. 3:2002;221-227.
119. D.M. Rothwarf, M. Karin, Sci. STKE (1999) 1999RE1.
120. Li N., Karin M. Methods Enzymol. 319:2000;273-279.
121. Schreck R., Albermann K., Baeuerle P.A. Free Radic. Res. Commun. 17:1992;221-237.
122. Schreck R., Rieber P., Baeuerle P.A. EMBO J. 10:1991;2247-2258.
123. Cargnoni A., Ceconi C., Gaia G., Agnoletti L., Ferrari R. J. Mol. Cell. Cardiol. 34:2002;997-1005.
124. Kukreja R.C. J. Mol. Cell. Cardiol. 34:2002;1301-1304.
125. Fan H., Sun B., Gu Q., Lafond-Walker A., Cao S., Becker L.C. Am. J. Physiol. Heart Circ. Physiol. 282:2002;H1778-H1786.
126. Li C., Kao R.L., Ha T., Kelley J., Browder I.W., Williams D.L. Am. J. Physiol. Heart Circ. Physiol. 280:2001;H1264-H1271.
127. Li C., Browder W., Kao R.L. Am. J. Physiol. 276:1999;H543-H552.
128. Morishita R., Sugimoto T., Aoki M., Kida I., Tomita N., Moriguchi A., Maeda K., Sawa Y., Kaneda Y., Higaki J., Ogihara T. Nat. Med. 3:1997;894-899.
129. Pye J., Ardeshirpour F., McCain A., Bellinger D.A., Merricks E., Adams J., Elliott P.J., Pien C., Fischer T.H., Baldwin A.S. Jr., Nichols T.C. Am. J. Physiol. Heart Circ. Physiol. 284:2003;H919-H926.
130. Sasaki H., Galang N., Maulik N. Antioxid. Redox Signal. 1:1999;317-324.
131. Valen G., Yan Z.Q., Hansson G.K. J. Am. Coll. Cardiol. 38:2001;307-314.
132. Florens E., Salvi S., Peynet J., Elbim C., Mallat Z., Bel A., Nguyen A., Tedgui A., Pasquier C., Menasche P. J. Card. Surg. 16:2001;232-239.
133. Bowie A., O'Neill L.A. Biochem. Pharmacol. 59:2000;13-23.
134. Li N., Karin M. FASEB J. 13:1999;1137-1143.
135. Hoare G.S., Chester A.H., Yacoub M.H., Marczin N. Int. J. Mol. Med. 9:2002;35-44.
136. Hoare G.S., Marczin N., Chester A.H., Yacoub M.H. Am. J. Physiol. 277:1999;H1975-H1984.
137. Marczin N., Bundy R.E., Hoare G.S., Yacoub M. Coron. Artery Dis. 14:2003;123-133.
138. Hayakawa M., Miyashita H., Sakamoto I., Kitagawa M., Tanaka H., Yasuda H., Karin M., Kikugawa K. EMBO J. 22:2003;3356-3366.
139. Saccani S., Pantano S., Natoli G. Nat. Immunol. 3:2002;69-75.
140. Saccani S., Pantano S., Natoli G. J. Exp. Med. 193:2001;1351-1359.
141. Gilmour P.S., Rahman I., Donaldson K., MacNee W. Am. J. Physiol. Lung. Cell Mol. Physiol. 284:2003;L533-L540.
142. Tomita K., Barnes P.J., Adcock I.M. Biochem. Biophys. Res. Commun. 301:2003;572-577.
143. Chen L.W., Egan L., Li Z.W., Greten F.R., Kagnoff M.F., Karin M. Nat. Med. 9:2003;575-581.
144. Lawrence T., Willoughby D.A., Gilroy D.W. Nat. Rev. Immunol. 2:2002;787-795.
145. Lawrence T., Gilroy D.W., Colville-Nash P.R., Willoughby D.A. Nat. Med. 7:2001;1291-1297.
146. Shaulian E., Karin M. Nat. Cell Biol. 4:2002;E131-E136.
147. Karin M. Ann. N. Y. Acad. Sci. 851:1998;139-146.
148. Abe J., Baines C.P., Berk B.C. Circ. Res. 86:2000;607-609.
149. Bogoyevitch M.A., Gillespie-Brown J., Ketterman A.J., Fuller S.J., Ben Levy R., Ashworth A., Marshall C.J., Sugden P.H. Circ. Res. 79:1996;162-173.
150. Knight R.J., Buxton D.B. Biochem. Biophys. Res. Commun. 218:1996;83-88.
151. Clerk A., Fuller S.J., Michael A., Sugden P.H. J. Biol. Chem. 273:1998;7228-7234.
152. Yue T.L., Wang C., Gu J.L., Ma X.L., Kumar S., Lee J.C., Feuerstein G.Z., Thomas H., Maleeff B., Ohlstein E.H. Circ. Res. 86:2000;692-699.
153. Otsu K., Yamashita N., Nishida K., Hirotani S., Yamaguchi O., Watanabe T., Hikoso S., Higuchi Y., Matsumura Y., Maruyama M., Sudo T., Osada H., Hori M. Biochem. Biophys. Res. Commun. 302:2003;56-60.
154. Talmor D., Applebaum A., Rudich A., Shapira Y., Tirosh A. Circ. Res. 86:2000;1004-1007.
155. Bogoyevitch M.A., Ng D.C., Court N.W., Draper K.A., Dhillon A., Abas L. J. Mol. Cell. Cardiol. 32:2000;1469-1480.
156. Qin F., Shite J., Liang C.S. Am. J. Physiol. Heart Circ. Physiol. 2003.
157. Kulisz A., Chen N., Chandel N.S., Shao Z., Schumacker P.T. Am. J. Physiol. Lung. Cell Mol. Physiol. 282:2002;L1324-L1329.
158. Wenzel S., Taimor G., Piper H.M., Schluter K.D. FASEB J. 15:2001;2291-2293.
159. Tanaka K., Honda M., Takabatake T. J. Am. Coll. Cardiol. 37:2001;676-685.
160. Bundy R.E., Marczin N., Chester A.H., Yacoub M. Br. J. Pharmacol. 129:2000;1513-1521.
161. Jiang B., Brecher P. Hypertension. 35:2000;914-918.
162. Arkan M.C., Leonarduzzi G., Biasi F., Basaga H., Poli G. Free Radic. Biol. Med. 31:2001;374-382.
163. Bowie A.G., O'Neill L.A. J. Immunol. 165:2000;7180-7188.
164. Nemoto S., Xiang J., Huang S., Lin A. J. Biol. Chem. 273:1998;16415- 16420.
165. Zhang X., Shan P., Otterbein L.E., Alam J., Flavell R.A., Davis R.J., Choi A.M., Lee P.J. J. Biol. Chem. 278:2003;1248-1258.