Grape seed proanthocyanidin reduces cardiomyocyte apoptosis by inhibiting ischemia/reperfusion-induced activation of JNK-1 and C-JUN

Free Radical Biology and Medicine

Volumn 31, Issue 6, 2001, Pages 729-737

  Sato, Motoaki ^a   Bagchi, Debasis ^b   Tosaki, Arpad ^a   Das, Dipak K ^a  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^b InterHealth Nutraceuticals Inc   (United States)

Author keywords

Alcohol; Apoptosis; C Jun; Cardiomyocytes; Free radicals; Heart; JNK; Proanthocyanidins; Wine

Indexed keywords

FREE RADICAL; MYOSIN HEAVY CHAIN; PROANTHOCYANIDIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DENSITOMETRY; DIET; ELECTRON SPIN RESONANCE; GENETIC TRANSCRIPTION; GRAPE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; NICK END LABELING; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; RAT; WESTERN BLOTTING; WINE;

ANIMALS; ANTHOCYANINS; ANTIOXIDANTS; APOPTOSIS; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENZYME ACTIVATION; FREE RADICALS; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION; MYOCARDIUM; PROANTHOCYANIDINS; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SEEDS; VITIS;

VITIS SP.;

EID: 0035884851     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00626-8     Document Type: Article

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