Early activation of transcription factor NF-κB during ischemia in perfused rat heart

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 276, Issue 2 45-2, 1999, Pages

  Li, Chuanfu ^a   Browder, William ^a   Kao, Race L ^a  

^a East Tennessee State University   (United States)

Author keywords

Antioxidant; Inhibitory protein I B ; Nuclear factor B; Reactive oxygen species; Reperfusion

Indexed keywords

ANTIOXIDANT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PROTEIN INHIBITOR; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GEL ELECTROPHORESIS; GENE EXPRESSION SYSTEM; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; IMMEDIATE EARLY GENE; IMMUNOBLOTTING; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

EID: 0032988969     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1999.276.2.h543     Document Type: Article

References (47)

1. Baeuerle, P. A., and D. Baltimore. NF-κB: ten years after. Cell 87: 13-20, 1996.
2. Baldwin, A. S., Jr. The NF-κB and IκB proteins: new discoveries and insights. Annu. Rev. Immunol. 14: 649-683, 1996.
3. Battle, J., T. Ha, C. Li, V. D. Beffa, P. Rice, J. Kalbfleisch, W. Browder, and D. Williams. Ligand binding to the (1→3)-β-D-glucan receptor stimulates NFκB activation, but not apoptosis in U937 cells. Biochem. Biophys. Res. Commun. 249: 499-504, 1998.
4. Beg, A. A., T. S. Finco, P. V. Nantermet, and A. S. Baldwin, Jr. Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of IκBα: a mechanism for NF-κB activation. Mol. Cell. Biol. 13: 3301-3310, 1993.
5. Bozkurt, B., S. B. Kribbs, F. J. Clubb, Jr., L. H. Michael, V. V. Didenko, P. J. Hormsby, Y. Seta, H. Oral, F. G. Spinale, and D. L. Mann. Pathophysiologically relevant concentrations of tumor necrosis factor-α promote progressive left ventricular dysfunction and remodeling in rats. Circulation 97: 1382-1391, 1988.
6. Brown, K., S. Park, T. Kanno, G. Franzoso, and U. Siebenlist. Mutual regulation of the transcriptional activator NF-κB and its inhibitor, IκBα. Proc. Natl. Acad. Sci. USA 90: 2532-2536, 1993.
7. Bryant, D., L. Becker, J. Richardson, J. Shelton, F. Franco, R. Peshock, M. Thompson, and B. Giroir. Cardiac failure in transgenic mice with myocardial expression of tumor necrosis factor-α. Circulation 97: 1375-1381, 1988.
8. Chandrasekar, B., and G. L. Freeman. Induction of nuclear factor κB and activation protein 1 in postischemic myocardium. FEBS Lett. 401: 30-34, 1997.
9. Chiao, P. J., S. Miyamoto, and I. M. Verma. Autoregulation of IκBα activity. Proc. Natl. Acad. Sci. USA 91: 28-32, 1994.
10. Cordle, S. R., R. Donald, M. A. Read, and J. Hawiger. Lipopolysaccharide induces phosphorylation of MAD3 and activation of c-rel and related NF-κB protein in human monocytic THP-1 cells. J. Biol. Chem. 268: 11803-11810, 1993.
11. Das, D. K., N. Maulik, and I. I. Moraru. Gene expression in acute myocardial stress. Induction by hypoxia, ischemia, reperfusion, hyperthermia and oxidative stress. J. Mol. Cell. Cardiol. 28: 181-193, 1995.
12. Depre, C., L. Fierain, and L. Hue. Activation of nitric oxide synthase by ischemia in the perfusion heart. Cardiovasc. Res. 33: 82-87, 1997.
13. Deryckere, F., and F. Gannon. A one-hour minipreparation technique for extraction of DNA-binding proteins from animal tissues. Biotechniques 16: 405, 1994.
14. Dunn, J. A., C. Li, T. Ha, R. L. Kao, and W. Browder. Therapeutic modification of nuclear factorKB binding activity and tumor necrosis factor-α gene expression during acute biliary pancreatitis. Am. Surg. 63: 1036-1044, 1997.
15. Garlic, P. B., M. J. Davies, D. J. Hearse, and T. F. Slater. Direct detection of free radicals in the reperfused rat heart using electron spin resonance spectroscopy. Circ. Res. 61: 757-760, 1987.
16. 1 receptor mRNA levels: absence of other neurochemical associations with the enhanced behavioral responses of lesioned rats. J. Neurochem. 63: 1282-1290, 1994.
17. Henkel, T., T. Machleidt, I. Alkalay, M. Kronke, Y. Ben-Neriah, and P. Baeuerle. Rapid proteolysis of IκBα is necessary for activation of transcription factor NF-κB. Nature 365: 182-185, 1993.
18. Herskowitz, A., S. Choi, A. A. Ansari, and S. Wesselingh. Cytokine mRNA expression in postischemic/reperfusion myocardium. Am. J. Pathol. 146: 419-428, 1995.
19. Kacimi, R., J. S. Karliner, F. Koudssi, and C. S. Long. Expression and regulation of adhesion molecules in cardiac cells by cytokines, response to acute hypoxia. Circ. Res. 82: 576-586, 1998.
20. Kao, R. L., V. R. Conti, and E. H. Williams. Effect of temperature during potassium arrest on myocardial metabolism and function. J. Thorac. Cardiovasc. Surg. 84: 243-249, 1982.
21. Kelly, R. A., and T. W. Smith. Cytokines and cardiac contractile function. Circulation 95: 778-781, 1997.
22. Kubota, T., C. F. McTiernan, C. S. Frye, S. E. Slawson, B. H. Lemster, A. P. Koretsky, J. Demetris, and A. M. Feldman. Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factor-α. Circ. Res. 81: 627-635, 1997.
23. Kukielka, G. L., C. W. Smith, G. J. LaRosa, A. M. Manning, L. H. Mendoza, T. J. Daly, B. J. Hughes, K. A. Youker, H. K. Hawkins, and L. H. Michael. Interleukin-8 gene induction in the myocardium after ischemia and reperfusion in vivo. J. Clin. Invest. 95: 89-103, 1995.
24. Kukielka, G. L., C. W. Smith, A. M. Manning, K. A. Youker, L. H. Michael, and M. L. Entman. Induction of interleukin-6 synthesis in the myocardium. Potential role in postreperfusion inflammatory injury. Circulation 92: 1866-1875, 1995.
25. Le Bail, O., R. Schmidt-Ullrich, and A. Israël. Promoter analysis of the gene encoding the IκBα/MAD3 inhibitor of NF-κB: positive regulation by members of the rel/NF-κB family. EMBO J. 12: 5043-5049, 1993.
26. Li, C., D. A. Ferguson, T. Ha, D. S. Chi, and E. Thomas. A highly specific and sensitive DNA probe derived from chromosomal DNA of Helicobacter pylori is useful for typing H. pylori isolates. J. Clin. Microbiol. 31: 2167-2162, 1993.
27. Lofquist, A. K., K. Mondal, J. S. Morris, and J. S. Haskill. Transcription-independent turnover of IκBα during monocyte adherence: implications for a translational component regulating IκBα/MAD-s mRNA levels. Mol. Cell. Biol. 15: 1737-1746, 1995.
28. Mann, D. L. Stress activated cytokines and the hearts. Cytokine Growth Factor Rev. 7: 341-354, 1996.
29. Maulik, N., S. Motoaki, B. D. Price, and D. K. Das. An essential role of NFκB in tyrosine kinase signaling of p38 MAP kinase regulation of myocardial adaptation to ischemia. FEBS Lett. 429: 365-369, 1998.
30. Meldrum, D. R. Tumor necrosis factor in the heart. Am. J. Physiol. 274 (Regulatory Integrative Comp. Physiol. 43): R577-R595, 1998.
31. Morishita, R., T. Sugimoto, M. Aoki, I. Kida, N. Tomita, A. Moriguchi, K. Maeda, Y. Sawa, Y. Kaneda, J. Higaki, and T. Ogihara. In vivo transcription of cis element "decoy" against nuclear factor-kappaB binding site prevents myocardial infarction. Nat. Med. 3: 894-899, 1997.
32. Nose, P. S. Cytokines and reperfusion injury. J. Card. Surg. 8, Suppl. 2: 305-308, 1993.
33. O'Neill, C. A., L. W. Fu, B. Halliwell, and J. C. Longhurst. Hydroxyl radical production during myocardial ischemia and reperfusion in cats. Am. J. Physiol. 271 (Heart Circ. Physiol. 40): H660-H667, 1996.
34. Pinkus, R., L. M. Weiner, and V. Daniel. Role of oxidants and antioxidants in the induction of AP-1, NF-κB, and glutathione S-transferase gene expression. J. Biol. Chem. 271: 13422-13429, 1996.
35. Read, M. A., M. Z. Whitley, A. J. Williams, and T. Collins. NF-κB and IκBα: an inducible regulatory system in endothelial activation. J. Exp. Med. 179: 503-512, 1994.
36. Sawa, Y., R. Morishita, K. Suzuki, K. Kagisaki, Y. Kaneda. K. Maeda, K. Kadoba, and H. Matsuda. A novel strategy for myocardial protection using in vivo transfection of cis element 'decoy' against NFκB binding site. Evidence for a role of NFκB in ischemia-reperfusion injury. Circulation 96, Suppl. II: II-280-II-285, 1997.
37. Schenk, H., M. Klein, W. Erdbrügger, W. Dröge, and K. Schulze-Osthoff. Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-κB and AP-1. Proc. Natl. Acad. Sci. USA 91: 1672-1676, 1994.
38. Schreck, R., K. Albermann, and P. A. Baeuerle. Nuclear factor kappa B: an oxidative stress-responsive transcription factor of eukaryotic cells (a review). Free Radic. Res. Commun. 17: 221-237, 1992.
39. Schulz, R., and W. Richard. Inhibition of nitric oxide synthesis protects the isolated working rabbit heart from ischemia-reperfusion injury. Cardiovasc. Res. 30: 432-439, 1995.
40. Shu, H. B., A. B. Agranoff, E. G. Nabel, K. Leung, C. S. Duckett, A. S. Neish, T. Collins, and G. J. Nabel. Differential regulation of vascular cell adhesion molecule 1 gene expression by specific NF-κB subunits in endothelial and epithelial cells. Mol. Cell. Biol. 13: 6283-6289, 1993.
41. Sun, S. C., P. A. Ganchi, D. W. Ballard, and W. C. Greene. NF-κB controls expression of inhibitor IκBα: evidence for an inducible autoregulatory pathway. Science 259: 1912-1915, 1993.
42. Suyang, H., R. Phillips, I. Douglas, and S. Ghosh. Role of unphosphorylated, newly synthesized IκB-β in persistent activation of NF-κB. Mol. Cell. Biol. 16: 5444-5449, 1996.
43. Thompson, J. E., R. J. Phillips, H. Erdjument-Bromage, P. Tempst, and S. Ghosh. IκB-β regulates the persistent response in a biphasic activation of NF-κB. Cell 80: 573-582, 1996.
44. Tosaki, A., I. E. Blasing, T. Pali, and B. Ebert. Heart protection and free radical trapping by DMPO during reperfusion in isolated working rat hearts. Free Radic. Biol. Med. 8: 363-372, 1990.
45. Van den Hoek, T. L., C. Li, Z. Shao, P. T. Schumacker, and L. B. Becker. Significant levels of oxidants are generated by isolated cardiomyocytes during ischemia prior to reperfusion. J. Mol. Cell. Cardiol. 29: 2571-2583, 1997.
46. Williams, E. H., R. L. Kao, and H. E. Morgan. Protein degradation and synthesis during recovery from myocardial ischemia. Am. J. Physiol. 240 (Endocrinol. Metab. 3): E268-E273, 1981.
47. Yamazaki, T., Y. Seko, T. Tamatani, M. Miyasaka, H. Yagita, H. Okumura, R. Nagai, and Y. Yazaki. Expression of intercellular adhesion molecule-1 in rat heart with ischemia/reperfusion and limitation of infarct size by treatment with antibodies against cell adhesion molecules. Am. J. Pathol. 143: 410-418, 1993.