Proteasome inhibition ablates activation of NF-κB in myocardial reperfusion and reduces reperfusion injury

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 284, Issue 3 53-3, 2003, Pages

  Pye, Joseph ^a   Ardeshirpour, Farhad ^a   McCain, Arlene ^a   Bellinger, Dwight A ^a,b   Merricks, Elizabeth ^a   Adams, Julian ^c   Elliott, Peter J ^c   Pien, Christine ^c   Fischer, Thomas H ^a   Baldwin Jr , Albert S ^b   Nichols, Timothy C ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

Inflammation; Multienzyme complexes; Myocardial contraction; Transcription factors

Indexed keywords

CREATINE KINASE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTACYSTIN BETA LACTONE; PROTEASOME; PROTEASOME INHIBITOR; TROPONIN I; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; FEMALE; HEART FUNCTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; REPERFUSION INJURY; SWINE;

EID: 0037370653     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00851.2002     Document Type: Article

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