Human cytochromes P450 associated with phase 1 metabolism of drugs and other xenobiotics: A compilation of substrates and inhibitors of the CYP1, CYP2 and CYP3 families

Current Medicinal Chemistry

Volumn 10, Issue 19, 2003, Pages 1955-1972

  Lewis, David F V ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

Cytochromes P450; Drug metabolism; Substate selectivity

Indexed keywords

3,5 DIMETHYL 2 (3 PYRIDYL) 4 THIAZOLIDINONE; AMFEBUTAMONE; CARBAMAZEPINE; COTININE; COUMARIN; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2A6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 INHIBITOR; DIAZEPAM; DRUG METABOLIZING ENZYME; ESTRADIOL; FADROZOLE; FURAFYLLINE; LOSIGAMONE; METHOXSALEN; NAPROXEN; PARACETAMOL; PHENACETIN; PILOCARPINE; TESTOSTERONE; THEOPHYLLINE; UNINDEXED DRUG; XENOBIOTIC AGENT; ZOXAZOLAMINE;

ACIDITY; DRUG METABOLISM; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME CHEMISTRY; ENZYME INHIBITION; ENZYME METABOLISM; ENZYME SUBSTRATE; HUMAN; LIPOPHILICITY; MICHAELIS CONSTANT; MOLECULAR MODEL; PHYSICAL CHEMISTRY; PROTEIN FAMILY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; STRUCTURE ANALYSIS;

CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; HUMANS; HYDROGEN BONDING; MOLECULAR STRUCTURE; PHARMACEUTICAL PREPARATIONS; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; XENOBIOTICS;

EID: 0141538249     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867033456855     Document Type: Review

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