Inter-individual differences in the metabolism of environmental toxicants: Cytochrome P450 1A2 as a prototype

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 428, Issue 1-2, 1999, Pages 115-124

  Guengerich, F Peter ^a   Parikh, Asit ^a   Turesky, Robert J ^b   Josephy, P David ^c  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NESTLÉ RESEARCH CENTER   (Switzerland)

^c UNIVERSITY OF GUELPH   (Canada)

Author keywords

Cytochrome P450, 1A2; Cytochrome P450, human; Dinitropyrene; Escherichia coli, expression of proteins in; Genetoxicity assay; Heterocyclic amine; Mutagenesis, random

Indexed keywords

HETEROCYCLIC AMINE; NITROPYRENE; PHENACETIN O DEETHYLASE; PYRENE DERIVATIVE;

CARCINOGENESIS; CATALYSIS; CONFERENCE PAPER; DRUG HYDROXYLATION; GENETIC POLYMORPHISM; GENOTOXICITY; HUMAN; LIVER MICROSOME METABOLISM; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TOXICOKINETICS;

AMINO ACID SUBSTITUTION; ANIMALS; CARCINOGENS, ENVIRONMENTAL; CYTOCHROME P-450 CYP1A2; HUMANS; LIVER; MUTAGENICITY TESTS; MUTAGENS; PYRENES; RATS; SPECIES SPECIFICITY; XENOBIOTICS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0032812946     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5742(99)00039-3     Document Type: Conference Paper

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