(+)-Cis-3,5-dimethyl-2-(3-pyridyl) thiazolidin-4-one hydrochloride (SM-12502) as a novel substrate for cytochrome P450 2A6 in human liver microsomes 1

Journal of Pharmacology and Experimental Therapeutics

Volumn 277, Issue 2, 1996, Pages 768-774

  Nunoya, Ken Ichi ^a   Yokoi, Tsuyoshi ^a   Kimura, Kanzo ^c   Kodama, Takao ^d   Funayama, Masato ^e   Inoue, Kazuaki ^f   Nagashima, Kazuo ^b   Funae, Yoshihiko ^g   Shimada, Noriaki ^h   Green, Carol ⁱ   Kamataki, Tetsuya ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^d Hokkaido Assoc Med Serv Workers   (Japan)

^e SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f HOKKAIDO UNIVERSITY HOSPITAL   (Japan)

^g OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^h DAIICHI PURE CHEMICALS CO LTD   (Japan)

ⁱ SRI INTERNATIONAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,5 DIMETHYL 2 (3 PYRIDYL) 4 THIAZOLIDINONE; CYTOCHROME P450; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; PROADIFEN; SULFAPHENAZOLE; THIOBENZAMIDE; TOLBUTAMIDE;

ARTICLE; DNA POLYMORPHISM; DRUG ABSORPTION; DRUG METABOLISM; ENZYME ACTIVITY; GENETIC ENGINEERING; HEMOCONCENTRATION; HUMAN; HUMAN CELL; HYDROXYLATION; LIVER MICROSOME; LYMPHOBLASTOID CELL; PRIORITY JOURNAL; STEREOCHEMISTRY;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; ISOENZYMES; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; OXIDATION-REDUCTION; RATS; THIAZOLES; THIAZOLIDINES;

EID: 0030435329     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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