The kinetics of aflatoxin B1 oxidation by human cDNA-expressed and human liver microsomal cytochromes P450 1A2 and 3A4

Toxicology and Applied Pharmacology

Volumn 141, Issue 2, 1996, Pages 595-606

  Gallagher, Evan P ^a   Kunze, Kent L ^a   Stapleton, Patricia L ^a   Eaton, David L ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN B1; COMPLEMENTARY DNA; CYTOCHROME P450 ISOENZYME; AFLATOXIN; AFLATOXIN B1 DNA ADDUCT; AFLATOXIN B1-DNA ADDUCT; AFLATOXIN Q1; CYP3A PROTEIN, HUMAN; CYP3A4 PROTEIN, HUMAN; CYTOCHROME P450; CYTOCHROME P450 1A2; MIXED FUNCTION OXIDASE; RECOMBINANT PROTEIN;

ARTICLE; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; DETOXIFICATION; HUMAN; HUMAN TISSUE; LIVER MICROSOME; LYMPHOBLASTOID CELL; METABOLIC ACTIVATION; OXIDATION; ADULT; DNA ADDUCT; KINETICS; MALE; METABOLISM; MIDDLE AGED; OXIDATION REDUCTION REACTION; PHYSIOLOGY;

ADULT; AFLATOXIN B1; AFLATOXINS; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; DNA ADDUCTS; HUMANS; KINETICS; MALE; MICROSOMES, LIVER; MIDDLE AGED; MIXED FUNCTION OXYGENASES; OXIDATION-REDUCTION; RECOMBINANT PROTEINS;

EID: 0030339769     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1996.0326     Document Type: Article

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