Role of human cytochrome P4502A6 in C-oxidation of nicotine

Drug Metabolism and Disposition

Volumn 24, Issue 11, 1996, Pages 1212-1217

  Nakajima, Miki ^a   Yamamoto, Toshinori ^a   Nunoya, Ken Ichi ^b   Yokoi, Tsuyoshi ^b   Nagashima, Kazuo ^c   Inoue, Kazuaki ^d   Funae, Yoshihiko ^e   Shimada, Noriaki ^f   Kamataki, Tetsuya ^b   Kuroiwa, Yukio ^a  

^a SHOWA UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

^d HOKKAIDO UNIVERSITY HOSPITAL   (Japan)

^e OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f DAIICHI PURE CHEMICALS CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3' HYDROXYCOTININE; 7 ETHOXYCOUMARIN; ALDEHYDE OXIDASE; ALPHA NAPHTHOFLAVONE; CHLORZOXAZONE; COMPLEMENTARY DNA; COTININE; COUMARIN; CYTOCHROME P450; ERYTHROMYCIN; GLUCOSE 6 PHOSPHATE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; MEPHENYTOIN; NICOTINE; OXYGENASE; QUININE; TOLBUTAMIDE; UMBELLIFERONE;

ARTICLE; B LYMPHOBLAST; CONTROLLED STUDY; DRUG HYDROXYLATION; DRUG OXIDATION; DRUG TRANSFORMATION; ENZYME KINETICS; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CYTOSOL; LIVER MICROSOME METABOLISM; LYMPHOBLASTOID CELL LINE; PHENOTYPE; PRIORITY JOURNAL;

ARYL HYDROCARBON HYDROXYLASES; B-LYMPHOCYTES; COTININE; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; HUMANS; HYDROXYLATION; IMMUNOCHEMISTRY; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; NICOTINE; OXIDATION-REDUCTION;

CINCHONA PUBESCENS; ORYCTOLAGUS CUNICULUS;

EID: 8044258385     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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