Characterization of moclobemide N-oxidation in human liver microsomes

Xenobiotica

Volumn 31, Issue 7, 2001, Pages 387-397

  Hoskins, J ^a   Shenfield, G ^a   Murray, M ^a   Gross, A ^a  

^a University of Sydney   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

1 BENZYLIMIDAZOLE; 4 [2 (4 CHLOROBENZAMIDO)ETHYL]MORPHOLINE 4 OXIDE; 4 CHLORO N [2 (3 OXOMORPHOLINO)ETHYL]BENZAMIDE; CYTOCHROME P450; CYTOCHROME P450 2C19; CYTOCHROME P450 2E1; CYTOCHROME P450 INHIBITOR; DIMETHYLANILINE MONOOXYGENASE; ISOENZYME; MOCLOBEMIDE; MORPHOLINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG OXIDATION; DRUG RETENTION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME METABOLISM; ENZYME SPECIFICITY; HEAT TREATMENT; HUMAN; HUMAN TISSUE; LIVER METABOLISM; LIVER MICROSOME; MICHAELIS MENTEN KINETICS; PH; XENOBIOTIC METABOLISM;

BENZAMIDES; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; HEAT; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; LIVER; MICROSOMES, LIVER; MOCLOBEMIDE; MODELS, CHEMICAL; MONOAMINE OXIDASE INHIBITORS; MORPHOLINES; OXYGEN; PROTEIN ISOFORMS; TEMPERATURE; TIME FACTORS;

EID: 0034885445     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/00498250110055488     Document Type: Article

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