Molecular mechanisms that regulate transcription factor localization suggest new targets for drug development

Advanced Drug Delivery Reviews

Volumn 55, Issue 6, 2003, Pages 717-731

  Lee, Sang Hyun ^a   Hannink, Mark ^a  

^a University of Missouri   (United States)

Author keywords

Gene expression; Gene regulation; Nuclear export; Nuclear import; Phosphorylation; Signal transduction

Indexed keywords

GENES; METABOLISM;

MOLECULAR MECHANISMS;

DRUG PRODUCTS;

ADAPTOR PROTEIN; AMINO ACID; APC PROTEIN; ARF PROTEIN; BETA CATENIN; CHOLESTEROL; CIS ACTING ELEMENT; DIGITONIN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KAPPA OPIATE RECEPTOR ANTAGONIST; KARYOPHERIN BETA; MEMBRANE PROTEIN; NOTCH RECEPTOR; NUCLEOPORIN; PHENYLALANYLLYSYLHISTIDYLARGINYLLEUCINE 1; PROTEIN MDM2; PROTEIN P53; PROTEIN PRECURSOR; RAN PROTEIN; STAT PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN; TRANS ACTING FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; WNT PROTEIN;

AMINO TERMINAL SEQUENCE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL COMMUNICATION; CELL COMPARTMENTALIZATION; CELL METABOLISM; CELL NUCLEUS; CYTOPLASM; DIFFUSION; DIMERIZATION; DNA BINDING; DYNAMICS; EUKARYOTE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HOMEOSTASIS; HUMAN; MOLECULAR MECHANICS; NONHUMAN; NUCLEAR IMPORT; NUCLEAR LOCALIZATION SIGNAL; NUCLEAR PORE COMPLEX; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; STEADY STATE; STIMULUS RESPONSE;

EID: 0038360785     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(03)00052-8     Document Type: Review

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