Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1

Cell

Volumn 93, Issue 5, 1998, Pages 851-861

  Zhu, Jiangyu ^a   Shibasaki, Futoshi ^a   Price, Roydon ^a   Guillemot, Jean Claude ^b   Yano, Takeo ^a   Dötsch, Volker ^a   Wagner, Gerhard ^a   Ferrara, Pascual ^b   McKeon, Frank ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN KINASE I; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; LYMPHOCYTE ACTIVATION; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALIA;

EID: 0032577673     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81445-2     Document Type: Article

References (34)

1. Atfi, A., Djelloul, S., Chastre, E., Davis, R., and Gespach, C. (1997). Evidence for a role of Rho-like GTPases and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) in transforming growth factor β-mediated signaling. J. Biol. Chem. 272, 1429-1432.
2. Baeuerle, P.A., and Baltimore, D. (1996). NF-κB: ten years after. Cell 87, 13-20.
3. Beals, C.R., Clipstone, N.A., Ho, S.N., and Crabtree, G.R. (1997a). Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction. Genes Dev. 11, 824-834.
4. Beals, C.R., Sheridan, C.M., Turck, C.W., Gardner, P., and Crabtree, G.R. (1997b). Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3. Science 275, 1930-1934.
5. Brockman, J.L., Gross, S.D., Sussman, M.R., and Anderson, R.A. (1992). Cell cycle-dependent localization of casein kinase I to mitotic spindles. Proc. Natl. Acad. Sci. USA 89, 9454-9458.
6. Cardone, M.H., Salvesen, G.S., Widmann, C., Johnson, G., and Frisch, S.M. (1997). The regulation of anoikis: MEKK-1 activation requires cleavage by caspases. Cell 90, 315-323.
7. Chow, C.W., Rincon, M., Cavanagh, J., Dickens, M., and Davis, R.J. (1997). Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway. Science 278, 1638-1641.
8. Fish, K.J., Cegielska, A., Getman, M.E., Landes, G.M., and Virshup, D.M. (1995). Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of t he CKI gene family. J. Biol. Chem. 270, 14875-14883.
9. Flotow, H., and Roach, P.J. (1991). Role of acidic residues as substrate determinants for casein kinase I. J. Biol. Chem. 266, 3724-3727.
10. Flotow, H., Graves, P.R., Wang, A.Q., Fiol, C.J., Roeske, R.W., and Roach, P.J. (1990). Phosphate groups as substrate determinants for casein kinase I action. J. Biol. Chem. 265, 14264-14269.
11. Gorlich, D. (1997). Nuclear protein import. Curr. Opin. Cell. Biol. 9, 412-419.
12. Graves, P.R., and Roach, P.J. (1995). Role of COOH-terminal phosphorylation in the regulation of casein kinase I delta. J. Biol. Chem. 270, 21689-21694.
13. Graves, P.R., Haas, D.W., Hagedorn, C.H., DePaoli-Roach, A.A., and Roach, P.J. (1993). Molecular cloning, expression, and characterization of a 49-kilodalton casein kinase I isoform from rat testis. J. Biol. Chem. 268, 6394-6401.
14. Hirano, M., Osada, S., Aoki, T., Hirai, S., Hosaka, M., Inoue, J., and Ohno, S. (1996). MEK kinase is involved in tumor necrosis factor α-induced NF-κB activation and degradation of IκB-α. J. Biol. Chem. 271, 13234-13238.
15. Ho, U., Mason, S., Kobayashi, R., Hoekstra, M., and Andrews, B. (1997). Role of the casein kinase I isoform , Hrr25, and the cell cycle-regulatory transcription factor, SBF, in the transcriptional response to DNA damage in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 94, 581-586.
16. Hoey, T., Sun, Y.L., Williamson, K., and Xu, X. (1995). Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins. Immunity 2, 461-472.
17. Jain, J., McCaffrey, P.G., Miner, Z., Kerppola, T.K., Lambert, J.N., Verdine, G.L., Curran, T., and Rao, A. (1993). The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. Nature 365, 352-355.
18. Kusuda, J., Hidari, N., Hirai, M., and Hashimoto, K. (1996). Sequence analysis of the cDNA for the human casein kinase I delta (CSNK1D) gene and its chromosomal localization. Genomics 32, 140-143.
19. Lee, F.S., Hagler, J., Chen, Z.J., and Maniatis, T. (1997). Activation of the IκB α kinase complex by MEKK1, a kinase of the JNK pathway. Cell 88, 213-222.
20. Loh, C., Shaw, K.T., Carew, J., Viola, J.P., Luo, C., Perrino, B.A., and Rao, A. (1996). Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity. J. Biol. Chem. 271, 10884-10891.
21. Longenecker, K.L., Roach, P.J., and Hurley, T.D. (1996). Three-dimensional structure of mammalian casein kinase I: molecular basis for phosphate recognition. J. Mol. Biol. 257, 618-631.
22. Masuda, E.S., Liu, J., Imamura, R., Imai, S.I., Arai, K.I., and Arai, N. (1997). Control of NFATxI nuclear translocation by a calcineurin-regulated inhibitory domain. Mol. Cell. Biol. 17, 2066-2075.
23. Rao, A., Luo, C., and Hogan, P.G. (1997). Transcription factors of the NFAT family: regulation and function. Annu. Rev. Immunol. 15, 707-747.
24. Read, M.A., Whitley, M.Z., Gupta, S., Pierce, J.W., Best, J., Davis, R.J., and Collins, T. (1997). Tumor necrosis factor α-induced E-selectin expression is activated by the nuclear factor-κB and c-JUN N-terminal kinase/p38 mitogen-activated protein kinase pathways. J. Biol. Chem. 272, 2753-2761.
25. Rowles, J., Slaughter, C., Moomaw, C., Hsu, J., and Cobb, M.H. (1991). Purification of casein kinase I and isolation of cDNAs encoding multiple casein kinase I-like enzymes. Proc. Natl. Acad. Sci. USA 88, 9548-9552.
26. Sanchez, I., Hughes, R.T., Mayer, B.J., Yee, K., Woodgett, J.R., Avruch, J., Kyriakis, J.M., and Zon, L.I. (1994). Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature 372, 794-798.
27. Shibasaki, F., Price, E.R., Milan, D., and McKeon, F. (1996). Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4. Nature 382, 370-373.
28. Taylor, S.S., and McKeon, F. (1997). Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage. Cell 89, 727-735.
29. Wesselborg, S., Fruman, D.A., Sagoo, J.K., Bierer, B.E., and Burakoff, S.J. (1996). Identification of a physical interaction between calcineurin and nuclear factor of activated T cells (NFATp). J. Biol. Chem. 271, 1274-1277.
30. Woronicz, J.D., Gao, X., Cao, Z., Rothe, M., and Goeddel, D.V. (1997). IκB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK. Science 278, 866-869.
31. Xu, R.M., Carmel, G., Sweet, R.M., Kuret, J., and Cheng, X. (1995). Crystal structure of casein kinase-1, a phosphate-directed protein kinase. EMBO J. 14, 1015-1023.
32. Van, M., Dai, T., Deak, J.C., Kyriakis, J.M., Zon, L.I., Woodgett, J.R., and Templeton, D.J. (1994). Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1. Nature 372, 798-800.
33. Zandi, E., Rothwarf, D.M., Delhase, M., Hayakawa, M., and Karin, M. (1997). The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κKB activation. Cell 91, 243-252.
34. Zhai, L., Graves, P.R., Robinson, L.C., Italiano, M., Culbertson, M.R., Rowles, J., Cobb, M.H., DePaoli-Roach, A.A., and Roach, P.J. (1995). Casein kinase I gamma subfamily: molecular cloning, expression, and characterization of three mammalian isoforms and complemenk tation of defects in the Saccharomyces cerevisiae YCK genes. J. Biol. Chem. 270, 12717-12724.