IκBβ, but Not IκBα, Functions as a Classical Cytoplasmic Inhibitor of NF-κB Dimers by Masking Both NF-κB Nuclear Localization Sequences in Resting Cells

Journal of Biological Chemistry

Volumn 276, Issue 48, 2001, Pages 45225-45235

  Malek, Shiva ^b   Chen, Yi ^c   Huxford, Tom ^c   Ghosh, Gourisankar ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Aurora Biosciences Corporation   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

DIMERS; PROTEINS;

NUCLEAR LOCALIZATION SIGNALS;

CELLS;

DIMER; GLUTAMIC ACID; I KAPPA B ALPHA; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROLINE; PROTEIN INHIBITOR; SERINE; THREONINE; DNA; DNA BINDING PROTEIN; DNA BINDING PROTEINS; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; HUMAN; HUMAN CELL; INTRACELLULAR SPACE; MASKING; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; ANIMAL; BINDING COMPETITION; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL LINE; CELL NUCLEUS; CHEMISTRY; CYTOPLASM; DIMERIZATION; DOSE RESPONSE; FIBROBLAST; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; HELA CELL; KINETICS; METABOLISM; MOLECULAR CLONING; MOUSE; PHYSIOLOGY; PLASMID; POLYACRYLAMIDE GEL ELECTROPHORESIS; SPECTROFLUOROMETRY; TIME;

ANIMALIA;

ANIMAL; BINDING, COMPETITIVE; CELL LINE; CELL NUCLEUS; CLONING, MOLECULAR; CYTOPLASM; DIMERIZATION; DNA; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FIBROBLASTS; GLUTAMIC ACID; HELA CELLS; HUMAN; KINETICS; MICE; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; NF-KAPPA B; NUCLEAR LOCALIZATION SIGNAL; PLASMIDS; PROLINE; PROTEIN BINDING; SERINE; SIGNAL TRANSDUCTION; SPECTROMETRY, FLUORESCENCE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; THREONINE; TIME FACTORS; TRANSFECTION;

EID: 0035976962     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M105865200     Document Type: Article

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