-
1
-
-
0033491981
-
Biology of the interleukin-2 receptor
-
Nelson, B. H., and D. M. Willerford. 1998. Biology of the interleukin-2 receptor. Adv. Immunol. 70:1.
-
(1998)
Adv. Immunol.
, vol.70
, pp. 1
-
-
Nelson, B.H.1
Willerford, D.M.2
-
3
-
-
0036372440
-
Transforming growth factor-β in T-cell biology
-
Gorelik, L., and R. A. Flavell. 2002. Transforming growth factor-β in T-cell biology. Nat. Rev. Immunol. 2:46.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 46
-
-
Gorelik, L.1
Flavell, R.A.2
-
4
-
-
0025360027
-
Regulatory effects of transforming growth factor-β on IL-2- and IL-4-dependent T cell-cycle progression
-
Ruegemer, J. J., S. N. Ho, J. A. Augustine, J. W. Schlager, M. P. Bell, D. J. McKean, and R. T. Abraham. 1990. Regulatory effects of transforming growth factor-β on IL-2- and IL-4-dependent T cell-cycle progression. J. Immunol. 144:1767.
-
(1990)
J. Immunol.
, vol.144
, pp. 1767
-
-
Ruegemer, J.J.1
Ho, S.N.2
Augustine, J.A.3
Schlager, J.W.4
Bell, M.P.5
McKean, D.J.6
Abraham, R.T.7
-
5
-
-
0022465625
-
Production of transforming growth factor β by human T lymphocytes and its potential role in the regulation of T cell growth
-
Kehrl, J. H., L. M. Wakefield, A. B. Roberts, S. Jakowlew, M. Alvarez-Mon, R. Derynck, M. B. Sporn, and A. S. Fauci. 1986. Production of transforming growth factor β by human T lymphocytes and its potential role in the regulation of T cell growth. J. Exp. Med. 163:1037.
-
(1986)
J. Exp. Med.
, vol.163
, pp. 1037
-
-
Kehrl, J.H.1
Wakefield, L.M.2
Roberts, A.B.3
Jakowlew, S.4
Alvarez-Mon, M.5
Derynck, R.6
Sporn, M.B.7
Fauci, A.S.8
-
6
-
-
0036356812
-
Interleukin-2 signaling and the maintenance of self-tolerance
-
Nelson, B. H. 2002. Interleukin-2 signaling and the maintenance of self-tolerance. Curr. Dir. Autoimmun. 5:92.
-
(2002)
Curr. Dir. Autoimmun.
, vol.5
, pp. 92
-
-
Nelson, B.H.1
-
7
-
-
0034131557
-
Abrogation of TGFβ signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
-
Gorelik, L., and R. A. Flavell. 2000. Abrogation of TGFβ signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity 12:171.
-
(2000)
Immunity
, vol.12
, pp. 171
-
-
Gorelik, L.1
Flavell, R.A.2
-
8
-
-
0031694552
-
Recent advances in the understanding of interleukin-2 signal transduction
-
Gesbert, F., M. Delespine-Carmagnat, and J. Bertoglio. 1998. Recent advances in the understanding of interleukin-2 signal transduction. J. Clin. Immunol. 18:307.
-
(1998)
J. Clin. Immunol.
, vol.18
, pp. 307
-
-
Gesbert, F.1
Delespine-Carmagnat, M.2
Bertoglio, J.3
-
9
-
-
0029875230
-
Different interleukin 2 receptor β-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation
-
Friedmann, M. C., T. S. Migone, S. M. Russell, and W. J. Leonard. 1996. Different interleukin 2 receptor β-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation. Proc. Natl. Acad. Sci. USA 93:2077.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 2077
-
-
Friedmann, M.C.1
Migone, T.S.2
Russell, S.M.3
Leonard, W.J.4
-
10
-
-
0028887937
-
Interaction of Shc with Grb2 regulates association of Grb2 with mSOS
-
Ravichandran, K. S., U. Lorenz, S. E. Shoelson, and S. J. Burakoff. 1995. Interaction of Shc with Grb2 regulates association of Grb2 with mSOS. Mol. Cell. Biol. 15:593.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 593
-
-
Ravichandran, K.S.1
Lorenz, U.2
Shoelson, S.E.3
Burakoff, S.J.4
-
11
-
-
0033826512
-
New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway
-
Gu, H., H. Maeda, J. J. Moon, J. D. Lord, M. Yoakim, B. H. Nelson, and B. G. Neel. 2000. New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway. Mol. Cell. Biol. 20:7109.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7109
-
-
Gu, H.1
Maeda, H.2
Moon, J.J.3
Lord, J.D.4
Yoakim, M.5
Nelson, B.H.6
Neel, B.G.7
-
12
-
-
0034657396
-
The role of Stat5a and Stat5b in signaling by IL-2 family cytokines
-
Lin, J. X., and W. J. Leonard. 2000. The role of Stat5a and Stat5b in signaling by IL-2 family cytokines. Oncogene 19:2566.
-
(2000)
Oncogene
, vol.19
, pp. 2566
-
-
Lin, J.X.1
Leonard, W.J.2
-
13
-
-
0032212138
-
The IL-2 receptor promotes proliferation, bcl-2 and bcl-x induction, but not cell viability through the adapter molecule Shc
-
Lord, J. D., B. C. McIntosh, P. D. Greenberg, and B. H. Nelson. 1998. The IL-2 receptor promotes proliferation, bcl-2 and bcl-x induction, but not cell viability through the adapter molecule Shc. J. Immunol. 161:4627.
-
(1998)
J. Immunol.
, vol.161
, pp. 4627
-
-
Lord, J.D.1
McIntosh, B.C.2
Greenberg, P.D.3
Nelson, B.H.4
-
14
-
-
0035451818
-
Phosphatidylinositol 3-kinase potentiates, but does not trigger, T cell proliferation mediated by the IL-2 receptor
-
Moon, J. J., and B. H. Nelson. 2001. Phosphatidylinositol 3-kinase potentiates, but does not trigger, T cell proliferation mediated by the IL-2 receptor. J. Immunol. 167:2714.
-
(2001)
J. Immunol.
, vol.167
, pp. 2714
-
-
Moon, J.J.1
Nelson, B.H.2
-
15
-
-
0034163579
-
The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5
-
Lord, J. D., B. C. McIntosh, P. D. Greenberg, and B. H. Nelson. 2000. The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5. J. Immunol. 164:2533.
-
(2000)
J. Immunol.
, vol.164
, pp. 2533
-
-
Lord, J.D.1
McIntosh, B.C.2
Greenberg, P.D.3
Nelson, B.H.4
-
16
-
-
0026496172
-
TGF β signals through a heteromeric protein kinase receptor complex
-
Wrana, J. L., L. Attisano, J. Carcamo, A. Zentella, J. Doody, M. Laiho, X. F. Wang, and J. Massague. 1992. TGF β signals through a heteromeric protein kinase receptor complex. Cell 71:1003.
-
(1992)
Cell
, vol.71
, pp. 1003
-
-
Wrana, J.L.1
Attisano, L.2
Carcamo, J.3
Zentella, A.4
Doody, J.5
Laiho, M.6
Wang, X.F.7
Massague, J.8
-
17
-
-
0029842713
-
MAD-related proteins in TGF-β signalling
-
Wrana, J. L., and L. Attisano. 1996. MAD-related proteins in TGF-β signalling. Trends Genet. 12:493.
-
(1996)
Trends Genet.
, vol.12
, pp. 493
-
-
Wrana, J.L.1
Attisano, L.2
-
19
-
-
0031685620
-
TGF-β signal transduction
-
Massague, J. 1998. TGF-β signal transduction. Annu. Rev. Biochem. 67:753.
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 753
-
-
Massague, J.1
-
20
-
-
0033168915
-
Regulation of Smad signalling by protein associations and signalling crosstalk
-
Zhang, Y., and R. Derynck. 1999. Regulation of Smad signalling by protein associations and signalling crosstalk. Trends Cell Biol. 9:274.
-
(1999)
Trends Cell Biol.
, vol.9
, pp. 274
-
-
Zhang, Y.1
Derynck, R.2
-
21
-
-
0029551805
-
Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction
-
Yamaguchi, K., K. Shirakabe, H. Shibuya, K. Irie, I. Oishi, N. Ueno, T. Taniguchi, E. Nishida, and K. Matsumoto. 1995. Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction. Science 270:2008.
-
(1995)
Science
, vol.270
, pp. 2008
-
-
Yamaguchi, K.1
Shirakabe, K.2
Shibuya, H.3
Irie, K.4
Oishi, I.5
Ueno, N.6
Taniguchi, T.7
Nishida, E.8
Matsumoto, K.9
-
22
-
-
0029940355
-
TAB1: An activator of the TAK1 MAPKKK in TGF-β signal transduction
-
Shibuya, H., K. Yamaguchi, K. Shirakabe, A. Tonegawa, Y. Gotoh, N. Ueno, K. Irie, E. Nishida, and K. Matsumoto. 1996. TAB1: an activator of the TAK1 MAPKKK in TGF-β signal transduction. Science 272:1179.
-
(1996)
Science
, vol.272
, pp. 1179
-
-
Shibuya, H.1
Yamaguchi, K.2
Shirakabe, K.3
Tonegawa, A.4
Gotoh, Y.5
Ueno, N.6
Irie, K.7
Nishida, E.8
Matsumoto, K.9
-
23
-
-
0034906821
-
TGF-β-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation
-
Perlman, R., W. P. Schiemann, M. W. Brooks, H. F. Lodish, and R. A. Weinberg. 2001. TGF-β-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation. Nat. Cell Biol. 3:708.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 708
-
-
Perlman, R.1
Schiemann, W.P.2
Brooks, M.W.3
Lodish, H.F.4
Weinberg, R.A.5
-
25
-
-
0032934979
-
Targeted disruption of Smad3 reveals an essential role in transforming growth factor β-mediated signal transduction
-
Datto, M. B., J. P. Frederick, L. Pan, A. J. Borton, Y. Zhuang, and X. F. Wang. 1999. Targeted disruption of Smad3 reveals an essential role in transforming growth factor β-mediated signal transduction. Mol. Cell. Biol. 19:2495.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 2495
-
-
Datto, M.B.1
Frederick, J.P.2
Pan, L.3
Borton, A.J.4
Zhuang, Y.5
Wang, X.F.6
-
26
-
-
0033104503
-
Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-β
-
Yang, X., J. J. Letterio, R. J. Lechleider, L. Chen, R. Hayman, H. Gu, A. B. Roberts, and C. Deng. 1999. Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-β. EMBO J. 18:1280.
-
(1999)
EMBO J.
, vol.18
, pp. 1280
-
-
Yang, X.1
Letterio, J.J.2
Lechleider, R.J.3
Chen, L.4
Hayman, R.5
Gu, H.6
Roberts, A.B.7
Deng, C.8
-
27
-
-
0028169444
-
Immune dysregulation in TGF-β 1-deficient mice
-
Christ, M., N. L. McCartney-Francis, A. B. Kulkarni, J. M. Ward, D. E. Mizel, C. L. Mackall, R. E. Gress, K. L. Hines, H. Tian, S. Karlsson, et al. 1994. Immune dysregulation in TGF-β 1-deficient mice. J. Immunol. 153:1936.
-
(1994)
J. Immunol.
, vol.153
, pp. 1936
-
-
Christ, M.1
McCartney-Francis, N.L.2
Kulkarni, A.B.3
Ward, J.M.4
Mizel, D.E.5
Mackall, C.L.6
Gress, R.E.7
Hines, K.L.8
Tian, H.9
Karlsson, S.10
-
28
-
-
0029618694
-
Early-onset multifocal inflammation in the transforming growth factor β1-null mouse is lymphocyte mediated
-
Diebold, R. J., M. J. Eis, M. Yin, I. Ormsby, G. P. Boivin, B. J. Darrow, J. E. Saffitz, and T. Doetschman. 1995. Early-onset multifocal inflammation in the transforming growth factor β1-null mouse is lymphocyte mediated. Proc. Natl. Acad. Sci. USA 92:12215.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 12215
-
-
Diebold, R.J.1
Eis, M.J.2
Yin, M.3
Ormsby, I.4
Boivin, G.P.5
Darrow, B.J.6
Saffitz, J.E.7
Doetschman, T.8
-
29
-
-
0029907123
-
Autoimmunity associated with TGF-β1-deficiency in mice is dependent on MHC class II antigen expression
-
Letterio, J. J., A. G. Geiser, A. B. Kulkarni, H. Dang, L. Kong, T. Nakabayashi, C. L. Mackall, R. E. Gress, and A. B. Roberts. 1996. Autoimmunity associated with TGF-β1-deficiency in mice is dependent on MHC class II antigen expression. J. Clin. Invest. 98:2109.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 2109
-
-
Letterio, J.J.1
Geiser, A.G.2
Kulkarni, A.B.3
Dang, H.4
Kong, L.5
Nakabayashi, T.6
Mackall, C.L.7
Gress, R.E.8
Roberts, A.B.9
-
30
-
-
0032428684
-
SARA, a FYVE domain protein that recruits Smad2 to the TGFβ receptor
-
Tsukazaki, T., T. A. Chiang, A. F. Davison, L. Attisano, and J. L. Wrana. 1998. SARA, a FYVE domain protein that recruits Smad2 to the TGFβ receptor. Cell 95:779.
-
(1998)
Cell
, vol.95
, pp. 779
-
-
Tsukazaki, T.1
Chiang, T.A.2
Davison, A.F.3
Attisano, L.4
Wrana, J.L.5
-
31
-
-
0036682952
-
Smad3 allostery links TGF-β receptor kinase activation to transcriptional control
-
Qin, B. Y., S. S. Lam, J. J. Correia, and K. Lin. 2002. Smad3 allostery links TGF-β receptor kinase activation to transcriptional control. Genes Dev. 16:1950.
-
(2002)
Genes Dev.
, vol.16
, pp. 1950
-
-
Qin, B.Y.1
Lam, S.S.2
Correia, J.J.3
Lin, K.4
-
32
-
-
0032101178
-
Direct binding of Smad3 and Smad4 to critical TGF β-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
-
Dennler, S., S. Itoh, D. Vivien, P. ten Dijke, S. Huet, and J. M. Gauthier. 1998. Direct binding of Smad3 and Smad4 to critical TGF β-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J. 17:3091.
-
(1998)
EMBO J.
, vol.17
, pp. 3091
-
-
Dennler, S.1
Itoh, S.2
Vivien, D.3
Ten Dijke, P.4
Huet, S.5
Gauthier, J.M.6
-
33
-
-
0031741487
-
Role of p300, a transcriptional coactivator, in signalling of TGF-β
-
Nishihara, A., J. I. Hanai, N. Okamoto, J. Yanagisawa, S. Kato, K. Miyazono, and M. Kawabata. 1998. Role of p300, a transcriptional coactivator, in signalling of TGF-β. Genes Cells 3:613.
-
(1998)
Genes Cells
, vol.3
, pp. 613
-
-
Nishihara, A.1
Hanai, J.I.2
Okamoto, N.3
Yanagisawa, J.4
Kato, S.5
Miyazono, K.6
Kawabata, M.7
-
34
-
-
0032482946
-
CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor β transcriptional responses in endothelial cells
-
Topper, J. N., M. R. DiChiara, J. D. Brown, A. J. Williams, D. Falb, T. Collins, and M. A. Gimbrone Jr. 1998. CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor β transcriptional responses in endothelial cells. Proc. Natl. Acad. Sci. USA 95:9506.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9506
-
-
Topper, J.N.1
DiChiara, M.R.2
Brown, J.D.3
Williams, A.J.4
Falb, D.5
Collins, T.6
Gimbrone M.A., Jr.7
-
35
-
-
0032528236
-
The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-β-induced transcriptional activation
-
Feng, X. H., Y. Zhang, R. Y. Wu, and R. Derynck. 1998. The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-β-induced transcriptional activation. Genes Dev. 12:2153.
-
(1998)
Genes Dev.
, vol.12
, pp. 2153
-
-
Feng, X.H.1
Zhang, Y.2
Wu, R.Y.3
Derynck, R.4
-
36
-
-
0032483493
-
Physical and functional interaction of SMADs and p300/CBP
-
Pouponnot, C., L. Jayaraman, and J. Massague. 1998. Physical and functional interaction of SMADs and p300/CBP. J. Biol. Chem. 273:22865.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 22865
-
-
Pouponnot, C.1
Jayaraman, L.2
Massague, J.3
-
37
-
-
0032527756
-
TGF-β-stimulated cooperation of smad proteins with the coactivators CBP/p300
-
Janknecht, R., N. J. Wells, and T. Hunter. 1998. TGF-β-stimulated cooperation of smad proteins with the coactivators CBP/p300. Genes Dev. 12:2114.
-
(1998)
Genes Dev.
, vol.12
, pp. 2114
-
-
Janknecht, R.1
Wells, N.J.2
Hunter, T.3
-
38
-
-
0033515620
-
A Smad transcriptional corepressor
-
Wotton, D., R. S. Lo, S. Lee, and J. Massague. 1999. A Smad transcriptional corepressor. Cell 97:29.
-
(1999)
Cell
, vol.97
, pp. 29
-
-
Wotton, D.1
Lo, R.S.2
Lee, S.3
Massague, J.4
-
39
-
-
0035066745
-
Ski/Sno and TGF-β signaling
-
Liu, X., Y. Sun, R. A. Weinberg, and H. F. Lodish. 2001. Ski/Sno and TGF-β signaling. Cytokine Growth Factor Rev. 12:1.
-
(2001)
Cytokine Growth Factor Rev.
, vol.12
, pp. 1
-
-
Liu, X.1
Sun, Y.2
Weinberg, R.A.3
Lodish, H.F.4
-
40
-
-
0033521032
-
c-Ski acts as a transcriptional co-repressor in transforming growth factor-β signaling through interaction with smads
-
Akiyoshi, S., H. Inoue, J. Hanai, K. Kusanagi, N. Nemoto, K. Miyazono, and M. Kawabata. 1999. c-Ski acts as a transcriptional co-repressor in transforming growth factor-β signaling through interaction with smads. J. Biol. Chem. 274:35269.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 35269
-
-
Akiyoshi, S.1
Inoue, H.2
Hanai, J.3
Kusanagi, K.4
Nemoto, N.5
Miyazono, K.6
Kawabata, M.7
-
41
-
-
0033213606
-
Interaction of the Ski oncoprotein with Smad3 regulates TGF-β signaling
-
Sun, Y., X. Liu, E. N. Eaton, W. S. Lane, H. F. Lodish, and R. A. Weinberg. 1999. Interaction of the Ski oncoprotein with Smad3 regulates TGF-β signaling. Mol. Cell 4:499.
-
(1999)
Mol. Cell
, vol.4
, pp. 499
-
-
Sun, Y.1
Liu, X.2
Eaton, E.N.3
Lane, W.S.4
Lodish, H.F.5
Weinberg, R.A.6
-
42
-
-
0033595704
-
Negative feedback regulation of TGF-β signaling by the SnoN oncoprotein
-
Stroschein, S. L., W. Wang, S. Zhou, Q. Zhou, and K. Luo. 1999. Negative feedback regulation of TGF-β signaling by the SnoN oncoprotein. Science 286:771.
-
(1999)
Science
, vol.286
, pp. 771
-
-
Stroschein, S.L.1
Wang, W.2
Zhou, S.3
Zhou, Q.4
Luo, K.5
-
43
-
-
0033638083
-
Smad transcriptional corepressors in TGF β family signaling
-
Wotton, D., and J. Massague. 2001. Smad transcriptional corepressors in TGF β family signaling. Curr. Top. Microbiol. Immunol. 254:145.
-
(2001)
Curr. Top. Microbiol. Immunol.
, vol.254
, pp. 145
-
-
Wotton, D.1
Massague, J.2
-
44
-
-
0034234964
-
A novel smad nuclear interacting protein, SNP, suppresses p300-dependent TGF-β signal transduction
-
Kim, R. H., D. Wang, M. Tsang, J. Martin, C. Huff, M. P. de Caestecker, W. T. Parks, X. Meng, R. J. Lechleider, T. Wang, and A. B. Roberts. 2000. A novel smad nuclear interacting protein, SNP, suppresses p300-dependent TGF-β signal transduction. Genes Dev. 14:1605.
-
(2000)
Genes Dev.
, vol.14
, pp. 1605
-
-
Kim, R.H.1
Wang, D.2
Tsang, M.3
Martin, J.4
Huff, C.5
De Caestecker, M.P.6
Parks, W.T.7
Meng, X.8
Lechleider, R.J.9
Wang, T.10
Roberts, A.B.11
-
45
-
-
2342666616
-
A novel link between the proteasome pathway and the signal transduction pathway of the bone morphogenetic proteins (BMPs)
-
Lin, Y., J. Martin, C. Gruendler, J. Farley, X. Meng, B. Y. Li, R. Lechleider, C. Huff, R. H. Kim, W. A. Grasser, et al. 2002. A novel link between the proteasome pathway and the signal transduction pathway of the bone morphogenetic proteins (BMPs). BMC Cell. Biol. 3:15.
-
(2002)
BMC Cell. Biol.
, vol.3
, pp. 15
-
-
Lin, Y.1
Martin, J.2
Gruendler, C.3
Farley, J.4
Meng, X.5
Li, B.Y.6
Lechleider, R.7
Huff, C.8
Kim, R.H.9
Grasser, W.A.10
-
46
-
-
0034671642
-
A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member HEF1
-
Liu, X., A. E. Elia, S. F. Law, E. A. Golemis, J. Farley, and T. Wang. 2000. A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member HEF1. EMBO J. 19:6759.
-
(2000)
EMBO J.
, vol.19
, pp. 6759
-
-
Liu, X.1
Elia, A.E.2
Law, S.F.3
Golemis, E.A.4
Farley, J.5
Wang, T.6
-
48
-
-
0033521118
-
INK4B induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines
-
INK4B induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines. J. Biol. Chem. 274:35053.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 35053
-
-
Rich, J.N.1
Zhang, M.2
Datto, M.B.3
Bigner, D.D.4
Wang, X.F.5
-
49
-
-
0032499789
-
Regulation of the human p21/WAF1/ Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members
-
Moustakas, A., and D. Kardassis. 1998. Regulation of the human p21/WAF1/ Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members. Proc. Natl. Acad. Sci. USA 95:6733.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6733
-
-
Moustakas, A.1
Kardassis, D.2
-
52
-
-
0023623241
-
TGF-β inhibition of endothelial cell proliferation: Alteration of EGF binding and EGF-induced growth-regulatory (competence) gene expression
-
Takehara, K., E. C. LeRoy, and G. R. Grotendorst. 1987. TGF-β inhibition of endothelial cell proliferation: alteration of EGF binding and EGF-induced growth-regulatory (competence) gene expression. Cell 49:415.
-
(1987)
Cell
, vol.49
, pp. 415
-
-
Takehara, K.1
LeRoy, E.C.2
Grotendorst, G.R.3
-
53
-
-
0023691647
-
Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor β
-
Coffey, R. J., Jr., C. C. Bascom, N. J. Sipes, R. Graves-Deal, B. E. Weissman, and H. L. Moses. 1988. Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor β. Mol. Cell. Biol. 8:3088.
-
(1988)
Mol. Cell. Biol.
, vol.8
, pp. 3088
-
-
Coffey R.J., Jr.1
Bascom, C.C.2
Sipes, N.J.3
Graves-Deal, R.4
Weissman, B.E.5
Moses, H.L.6
-
54
-
-
0027241250
-
Effect of transforming growth factor-β on early and late activation events in human T cells
-
Ahuja, S. S., F. Paliogianni, H. Yamada, J. E. Balow, and D. T. Boumpas. 1993. Effect of transforming growth factor-β on early and late activation events in human T cells. J. Immunol. 150:3109.
-
(1993)
J. Immunol.
, vol.150
, pp. 3109
-
-
Ahuja, S.S.1
Paliogianni, F.2
Yamada, H.3
Balow, J.E.4
Boumpas, D.T.5
-
55
-
-
0031180973
-
TGF-β inhibits IL-2-induced tyrosine phosphorylation and activation of Jak-1 and Stat 5 in T lymphocytes
-
Bright, J. J., L. D. Kerr, and S. Sriram. 1997. TGF-β inhibits IL-2-induced tyrosine phosphorylation and activation of Jak-1 and Stat 5 in T lymphocytes. J. Immunol. 159:175.
-
(1997)
J. Immunol.
, vol.159
, pp. 175
-
-
Bright, J.J.1
Kerr, L.D.2
Sriram, S.3
-
57
-
-
0035399605
-
Suppression of IL-2-induced T cell proliferation and phosphorylation of STAT3 and STAT5 by tumor-derived TGF β is reversed by IL-15
-
Campbell, J. D., G. Cook, S. E. Robertson, A. Fraser, K. S. Boyd, J. A. Gracie, and I. M. Franklin. 2001. Suppression of IL-2-induced T cell proliferation and phosphorylation of STAT3 and STAT5 by tumor-derived TGF β is reversed by IL-15. J. Immunol. 167:553.
-
(2001)
J. Immunol.
, vol.167
, pp. 553
-
-
Campbell, J.D.1
Cook, G.2
Robertson, S.E.3
Fraser, A.4
Boyd, K.S.5
Gracie, J.A.6
Franklin, I.M.7
-
58
-
-
0033106371
-
TGF-β does not inhibit IL-12- and IL-2-induced activation of Janus kinases and STATs
-
Sudarshan, C., J. Galon, Y. Zhou, and J. J. O'Shea. 1999. TGF-β does not inhibit IL-12- and IL-2-induced activation of Janus kinases and STATs. J. Immunol. 162:2974.
-
(1999)
J. Immunol.
, vol.162
, pp. 2974
-
-
Sudarshan, C.1
Galon, J.2
Zhou, Y.3
O'Shea, J.J.4
-
59
-
-
0028286628
-
Cytoplasmic domains of the interleukin-2 receptor β and γ chains mediate the signal for T-cell proliferation
-
Nelson, B. H., J. D. Lord, and P. D. Greenberg. 1994. Cytoplasmic domains of the interleukin-2 receptor β and γ chains mediate the signal for T-cell proliferation. Nature 369:333.
-
(1994)
Nature
, vol.369
, pp. 333
-
-
Nelson, B.H.1
Lord, J.D.2
Greenberg, P.D.3
-
60
-
-
0030886204
-
Transforming growth factor β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells
-
Liu, X., Y. Sun, S. N. Constantinescu, E. Karam, R. A. Weinberg, and H. F. Lodish. 1997. Transforming growth factor β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells. Proc. Natl. Acad. Sci. USA 94:10669.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10669
-
-
Liu, X.1
Sun, Y.2
Constantinescu, S.N.3
Karam, E.4
Weinberg, R.A.5
Lodish, H.F.6
-
61
-
-
17944383969
-
A sequence of the CIS gene promoter interacts preferentially with two associated STAT5A dimers: A distinct biochemical difference between STAT5A and STAT5B
-
Verdier, F., R. Rabionet, F. Gouilleux, C. Beisenherz-Huss, P. Varlet, O. Muller, P. Mayeux, C. Lacombe, S. Gisselbrecht, and S. Chretien. 1998. A sequence of the CIS gene promoter interacts preferentially with two associated STAT5A dimers: a distinct biochemical difference between STAT5A and STAT5B. Mol. Cell. Biol. 18:5852.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 5852
-
-
Verdier, F.1
Rabionet, R.2
Gouilleux, F.3
Beisenherz-Huss, C.4
Varlet, P.5
Muller, O.6
Mayeux, P.7
Lacombe, C.8
Gisselbrecht, S.9
Chretien, S.10
-
62
-
-
0035253352
-
Stat5 and Sp1 regulate transcription of the cyclin D2 gene in response to IL-2
-
Martino, A., J. H. Holmes, J. D. Lord, J. J. Moom, and B. H. Nelson. 2001. Stat5 and Sp1 regulate transcription of the cyclin D2 gene in response to IL-2. J. Immunol. 166:1723.
-
(2001)
J. Immunol.
, vol.166
, pp. 1723
-
-
Martino, A.1
Holmes, J.H.2
Lord, J.D.3
Moom, J.J.4
Nelson, B.H.5
-
63
-
-
0034883129
-
Growth factor signaling in cell survival: Implications for cancer treatment
-
Talapatra, S., and C. B. Thompson. 2001. Growth factor signaling in cell survival: implications for cancer treatment. J. Pharmacol. Exp. Ther. 298:873.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.298
, pp. 873
-
-
Talapatra, S.1
Thompson, C.B.2
-
64
-
-
0025344028
-
TGF-β1 inhibition of transin/stromelysin gene expression is mediated through a Fos binding sequence
-
Kerr, L. D., D. B. Miller, and L. M. Matrisian. 1990. TGF-β1 inhibition of transin/stromelysin gene expression is mediated through a Fos binding sequence. Cell 61:267.
-
(1990)
Cell
, vol.61
, pp. 267
-
-
Kerr, L.D.1
Miller, D.B.2
Matrisian, L.M.3
-
65
-
-
0033200361
-
The Ski oncoprotein interacts with the Smad proteins to repress TGFβ signaling
-
Luo, K., S. L. Stroschein, W. Wang, D. Chen, E. Martens, S. Zhou, and Q. Zhou. 1999. The Ski oncoprotein interacts with the Smad proteins to repress TGFβ signaling. Genes Dev. 13:2196.
-
(1999)
Genes Dev.
, vol.13
, pp. 2196
-
-
Luo, K.1
Stroschein, S.L.2
Wang, W.3
Chen, D.4
Martens, E.5
Zhou, S.6
Zhou, Q.7
-
66
-
-
0035399833
-
The Smad3 protein is involved in TGF-β inhibition of class II transactivator and class II MHC expression
-
Dong, Y., L. Tang, J. J. Letterio, and E. N. Benveniste. 2001. The Smad3 protein is involved in TGF-β inhibition of class II transactivator and class II MHC expression. J. Immunol. 167:311.
-
(2001)
J. Immunol.
, vol.167
, pp. 311
-
-
Dong, Y.1
Tang, L.2
Letterio, J.J.3
Benveniste, E.N.4
-
67
-
-
0037067653
-
E2F4/5 and p107 as Smad cofactors linking the TGFβ receptor to c-myc repression
-
Chen, C. R., Y. Kang, P. M. Siegel, and J. Massague. 2002. E2F4/5 and p107 as Smad cofactors linking the TGFβ receptor to c-myc repression. Cell 110:19.
-
(2002)
Cell
, vol.110
, pp. 19
-
-
Chen, C.R.1
Kang, Y.2
Siegel, P.M.3
Massague, J.4
-
68
-
-
0037016689
-
c-myc is a downstream target of the Smad pathway
-
Yagi, K., M. Furuhashi, H. Aoki, D. Goto, H. Kuwano, K. Sugamura, K. Miyazono, and M. Kato. 2002. c-myc is a downstream target of the Smad pathway. J. Biol. Chem. 277:854.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 854
-
-
Yagi, K.1
Furuhashi, M.2
Aoki, H.3
Goto, D.4
Kuwano, H.5
Sugamura, K.6
Miyazono, K.7
Kato, M.8
-
69
-
-
0035202540
-
Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells
-
Tzachanis, D., G. J. Freeman, N. Hirano, A. A. van Puijenbroek, M. W. Delfs, A. Berezovskaya, L. M. Nadler, and V. A. Boussiotis. 2001. Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells. Nat. Immunol. 2:1174.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 1174
-
-
Tzachanis, D.1
Freeman, G.J.2
Hirano, N.3
Van Puijenbroek, A.A.4
Delfs, M.W.5
Berezovskaya, A.6
Nadler, L.M.7
Boussiotis, V.A.8
-
70
-
-
0035816686
-
Smad proteins suppress CCAAT/ enhancer-binding protein (C/EBP) β- and STAT3-mediated transcriptional activation of the haptoglobin promoter
-
Zauberman, A., S. Lapter, and D. Zipori. 2001. Smad proteins suppress CCAAT/ enhancer-binding protein (C/EBP) β- and STAT3-mediated transcriptional activation of the haptoglobin promoter. J. Biol. Chem. 276:24719.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24719
-
-
Zauberman, A.1
Lapter, S.2
Zipori, D.3
-
71
-
-
0035914339
-
Transforming growth factor-β repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3
-
Yuan, W., and J. Varga. 2001. Transforming growth factor-β repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3. J. Biol. Chem. 276:38502.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38502
-
-
Yuan, W.1
Varga, J.2
-
72
-
-
0033607240
-
SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor β signaling
-
Sun, Y., X. Liu, E. Ng-Eaton, H. F. Lodish, and R. A. Weinberg. 1999. SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor β signaling. Proc. Natl. Acad. Sci. USA 96:12442.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 12442
-
-
Sun, Y.1
Liu, X.2
Ng-Eaton, E.3
Lodish, H.F.4
Weinberg, R.A.5
-
73
-
-
0028178471
-
Transforming growth factor-β2 induces apoptosis of murine T cell clones without down-regulating bcl-2 mRNA expression
-
Weller, M., D. B. Constam, U. Malipiero, and A. Fontana. 1994. Transforming growth factor-β2 induces apoptosis of murine T cell clones without down-regulating bcl-2 mRNA expression. Eur. J. Immunol. 24:1293.
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 1293
-
-
Weller, M.1
Constam, D.B.2
Malipiero, U.3
Fontana, A.4
-
74
-
-
0035920554
-
Requirement for transforming growth factor β1 in controlling T cell apoptosis
-
Chen, W., W. Jin, H. Tian, P. Sicurello, M. Frank, J. M. Orenstein, and S. M. Wahl. 2001. Requirement for transforming growth factor β1 in controlling T cell apoptosis. J. Exp. Med. 194:439.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 439
-
-
Chen, W.1
Jin, W.2
Tian, H.3
Sicurello, P.4
Frank, M.5
Orenstein, J.M.6
Wahl, S.M.7
-
75
-
-
0030030037
-
Fas- and activationinduced apoptosis are reduced in human T cells preactivated in the presence of TGF-β1
-
Cerwenka, A., H. Kovar, O. Majdic, and W. Holter. 1996. Fas- and activationinduced apoptosis are reduced in human T cells preactivated in the presence of TGF-β1. J. Immunol. 156:459.
-
(1996)
J. Immunol.
, vol.156
, pp. 459
-
-
Cerwenka, A.1
Kovar, H.2
Majdic, O.3
Holter, W.4
-
77
-
-
0029149596
-
Control of CD4 effector fate: Transforming growth factor β1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion
-
Zhang, X., L. Giangreco, H. E. Broome, C. M. Dargan, and S. L. Swain. 1995. Control of CD4 effector fate: transforming growth factor β1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion. J. Exp. Med. 182:699.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 699
-
-
Zhang, X.1
Giangreco, L.2
Broome, H.E.3
Dargan, C.M.4
Swain, S.L.5
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