Smad3 allostery links TGF-β receptor kinase activation to transcriptional control

Genes and Development

Volumn 16, Issue 15, 2002, Pages 1950-1963

  Qin, Bin Y ^a   Lam, Suvana S ^a   Correia, John J ^b   Lin, Kai ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

Allosteric; Phosphorylation; Signaling; Smad; TGF

Indexed keywords

MEMBRANE PROTEIN; PROTEIN TYROSINE KINASE; SMAD ANCHOR FOR RECEPTOR ACTIVATION; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CELL NUCLEUS; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME PHOSPHORYLATION; GEL PERMEATION CHROMATOGRAPHY; HYDROPHOBICITY; MUTAGENESIS; OLIGOMERIZATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ULTRACENTRIFUGATION; X RAY CRYSTALLOGRAPHY;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; BINDING SITES; CARRIER PROTEINS; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HUMANS; HYDROPHOBICITY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN INTERACTION MAPPING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; SERINE ENDOPEPTIDASES; SMAD3 PROTEIN; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

EID: 0036682952     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1002002     Document Type: Article

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