-
2
-
-
0028894025
-
Disruption of transforming growth factor β signaling by a mutation that prevents transphosphorylation within the receptor complex
-
Cárcamo, J., Zentella, A. & Massagué, J. (1995) Disruption of transforming growth factor β signaling by a mutation that prevents transphosphorylation within the receptor complex. Mol. Cell. Biol. 15, 1573-1581.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 1573-1581
-
-
Cárcamo, J.1
Zentella, A.2
Massagué, J.3
-
3
-
-
0030961168
-
Smad4 and FAST-1 in the assembly of activin-responsive factor
-
Chen, X., . Weisberg, E., Fridmacher, V., Watanabe, M., Naco, G. & Whitman, M. (1997) Smad4 and FAST-1 in the assembly of activin-responsive factor. Nature 389, 85-89.
-
(1997)
Nature
, vol.389
, pp. 85-89
-
-
Chen, X.1
Weisberg, E.2
Fridmacher, V.3
Watanabe, M.4
Naco, G.5
Whitman, M.6
-
4
-
-
0029802485
-
A transcriptional partner for MAD proteins in TGF-β signalling
-
Chen, X., Rubock, M.J. & Whitman, M. (1996) A transcriptional partner for MAD proteins in TGF-β signalling. Nature 383, 691-696.
-
(1996)
Nature
, vol.383
, pp. 691-696
-
-
Chen, X.1
Rubock, M.J.2
Whitman, M.3
-
5
-
-
0027433708
-
Phosphorylated CREB binds specifically to the nuclear protein CBP
-
Chrivia, J.C., Kwok, R.P., Lamb, N., Hagiwara, M., Montminy, M.R. & Goodman, R.H. (1993) Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365, 855-859.
-
(1993)
Nature
, vol.365
, pp. 855-859
-
-
Chrivia, J.C.1
Kwok, R.P.2
Lamb, N.3
Hagiwara, M.4
Montminy, M.R.5
Goodman, R.H.6
-
6
-
-
0027966909
-
Transforming growth factor β1-mediated induction of junB is selectively inhibited by expression of Ad.12-E1A
-
Coussens, L.M., Yokoyama, K. & Chiu, R. (1994) Transforming growth factor β1-mediated induction of junB is selectively inhibited by expression of Ad.12-E1A. J. Cell. Physiol. 160, 435-444.
-
(1994)
J. Cell. Physiol.
, vol.160
, pp. 435-444
-
-
Coussens, L.M.1
Yokoyama, K.2
Chiu, R.3
-
7
-
-
0030938916
-
The viral oncoprotein E1A blocks transforming growth factor β-mediated induction of p21/WAF1/Cip1 and p15/ INK4B
-
Datto, M.B., Hu, P.P., Kowalik, T.F., Yingling, J. & Wang, X.-F. (1997) The viral oncoprotein E1A blocks transforming growth factor β-mediated induction of p21/WAF1/Cip1 and p15/ INK4B. Mol. Cell. Biol. 17, 2030-2037.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2030-2037
-
-
Datto, M.B.1
Hu, P.P.2
Kowalik, T.F.3
Yingling, J.4
Wang, X.-F.5
-
8
-
-
0032101178
-
Direct binding of Smad3 and Smad4 to critical TGFβ-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
-
Dennler, S., Itoh, S., Vivien, D., ten Dijke, P., Huet, S. & Gauthier, J.M. (1998) Direct binding of Smad3 and Smad4 to critical TGFβ-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J. 17, 3091-3100.
-
(1998)
EMBO J.
, vol.17
, pp. 3091-3100
-
-
Dennler, S.1
Itoh, S.2
Vivien, D.3
Ten Dijke, P.4
Huet, S.5
Gauthier, J.M.6
-
10
-
-
0028296414
-
Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor
-
Eckner, R., Ewen, M.E., Newsome, D., et al. (1994) Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev. 8, 869-884.
-
(1994)
Genes Dev.
, vol.8
, pp. 869-884
-
-
Eckner, R.1
Ewen, M.E.2
Newsome, D.3
-
11
-
-
0030915270
-
A c-Fos- and E1A-interacting component of the tissue factor basal promoter complex mediates synergistic activation of transcription by transforming growth factor-β1
-
Felts, S.J., Stang, M.T. & Getz, M.J. (1997) A c-Fos- and E1A-interacting component of the tissue factor basal promoter complex mediates synergistic activation of transcription by transforming growth factor-β1. Oncogene 14, 679-1685.
-
(1997)
Oncogene
, vol.14
, pp. 679-1685
-
-
Felts, S.J.1
Stang, M.T.2
Getz, M.J.3
-
12
-
-
0032528236
-
The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-β-induced transcriptional activation
-
Feng, X.-H., Zhang, Y., Wu, R.-Y. & Derynck, R. (1998) The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-β-induced transcriptional activation. Genes Dev. 12, 2153-2163.
-
(1998)
Genes Dev.
, vol.12
, pp. 2153-2163
-
-
Feng, X.-H.1
Zhang, Y.2
Wu, R.-Y.3
Derynck, R.4
-
13
-
-
0032479464
-
A single missense mutant of Smad3 inhibits activation of both Smad2 and Smad3, and has a dominant negative effect on TGF-β signals
-
Goto, D., Yagi, K., Inoue, H., et al. (1998) A single missense mutant of Smad3 inhibits activation of both Smad2 and Smad3, and has a dominant negative effect on TGF-β signals. FEES Lett., 430, 201-204.
-
(1998)
FEES Lett.
, vol.430
, pp. 201-204
-
-
Goto, D.1
Yagi, K.2
Inoue, H.3
-
14
-
-
0029940972
-
Xenopus Mad proteins transduce distinct subsets of signals for the TGFβ superfamily
-
Graff, J.M., Bansal, A. & Melton, D.A. (1996) Xenopus Mad proteins transduce distinct subsets of signals for the TGFβ superfamily. Cell 85, 479-487.
-
(1996)
Cell
, vol.85
, pp. 479-487
-
-
Graff, J.M.1
Bansal, A.2
Melton, D.A.3
-
15
-
-
0030996361
-
Synergistic activation of transcription by CBP and p53
-
Gu, W., Shi, X.-L. & Roeder, R.G. (1997) Synergistic activation of transcription by CBP and p53. Nature 387, 819-823.
-
(1997)
Nature
, vol.387
, pp. 819-823
-
-
Gu, W.1
Shi, X.-L.2
Roeder, R.G.3
-
16
-
-
0027437850
-
Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2
-
Gyuris, J., Golemis, E., Chertkov, H. & Brent, R. (1993) Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell 75, 791-803.
-
(1993)
Cell
, vol.75
, pp. 791-803
-
-
Gyuris, J.1
Golemis, E.2
Chertkov, H.3
Brent, R.4
-
17
-
-
0030825516
-
Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4
-
Hata, A., Lo, R.S., Wotton, D., Lagna, G. & Massagué, J. (1997) Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4. Nature 388, 82-87.
-
(1997)
Nature
, vol.388
, pp. 82-87
-
-
Hata, A.1
Lo, R.S.2
Wotton, D.3
Lagna, G.4
Massagué, J.5
-
18
-
-
0031587828
-
The MAD-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling
-
Hayashi, H., Abdollah, S., Qiu, Y., et al. (1997) The MAD-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling. Cell 89, 1165-1173.
-
(1997)
Cell
, vol.89
, pp. 1165-1173
-
-
Hayashi, H.1
Abdollah, S.2
Qiu, Y.3
-
19
-
-
0031438047
-
TGF-β signalling from cell membrane to nucleus through SMAD proteins
-
Heldin, C.-H., Miyazono, K. & ten Dijke, P. (1997) TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature 390, 465-471.
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.-H.1
Miyazono, K.2
Ten Dijke, P.3
-
20
-
-
0029892494
-
MADR1, a MAD-related protein that functions in BMP2 signaling pathways
-
Hoodless, P.A., Haerry, T., Abdollah, S., et al. (1996) MADR1, a MAD-related protein that functions in BMP2 signaling pathways. Cell 85, 489-500.
-
(1996)
Cell
, vol.85
, pp. 489-500
-
-
Hoodless, P.A.1
Haerry, T.2
Abdollah, S.3
-
21
-
-
0030765945
-
Smad6 inhibits signalling by the TGF-β superfamily
-
Imamura, T., Takase, M., Nishihara, A., et al. (1997) Smad6 inhibits signalling by the TGF-β superfamily. Nature 389, 622-626.
-
(1997)
Nature
, vol.389
, pp. 622-626
-
-
Imamura, T.1
Takase, M.2
Nishihara, A.3
-
22
-
-
0031876205
-
Interplay of signal meds of decapentaplegic (Dpp): Molecular characterization of Mothers against dpp, Medea, and Daughters against dpp
-
Inoue, H., Imamura, T., Ishidou, Y., et al. (1998) Interplay of signal meds of decapentaplegic (Dpp): Molecular characterization of Mothers against dpp, Medea, and Daughters against dpp. Mol. Biol. Cell 9, 2145-2156.
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 2145-2156
-
-
Inoue, H.1
Imamura, T.2
Ishidou, Y.3
-
23
-
-
0032527756
-
TGF-β-stimulated cooperation of Smad proteins with the coactivators CBP/p300
-
Janknecht, R., Wells, N.J. & Hunter, T. (1998) TGF-β-stimulated cooperation of Smad proteins with the coactivators CBP/p300. Genes Dev. 12, 2114-2119.
-
(1998)
Genes Dev.
, vol.12
, pp. 2114-2119
-
-
Janknecht, R.1
Wells, N.J.2
Hunter, T.3
-
24
-
-
0029610361
-
Interaction of the transforming growth factor-β type I receptor with farnesyl-protein transferase-α
-
Kawabata, M., Imamura, T., Miyazono, K., Engel, M.E. & Moses, H.L. (1995) Interaction of the transforming growth factor-β type I receptor with farnesyl-protein transferase-α. J. Biol. Chem. 270, 29628-29631.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 29628-29631
-
-
Kawabata, M.1
Imamura, T.2
Miyazono, K.3
Engel, M.E.4
Moses, H.L.5
-
25
-
-
0032528041
-
Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/ threonine kinase receptors
-
Kawabata, M., Inoue, H., Hanyu, A., Imamura, T. & Miyazono, K. (1998) Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/ threonine kinase receptors. EMBO J. 17, 4056-4065.
-
(1998)
EMBO J.
, vol.17
, pp. 4056-4065
-
-
Kawabata, M.1
Inoue, H.2
Hanyu, A.3
Imamura, T.4
Miyazono, K.5
-
26
-
-
0030872367
-
Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic
-
Kim, J., Johnson, K., Chen, H.J., Carroll, S. & Laughon, A. (1997) Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic. Nature 388, 304-308.
-
(1997)
Nature
, vol.388
, pp. 304-308
-
-
Kim, J.1
Johnson, K.2
Chen, H.J.3
Carroll, S.4
Laughon, A.5
-
27
-
-
0028180315
-
The TGF-β superfamily: New members, new receptors, and new genetic tests of function in different organisms
-
Kingsley, D.M. (1994) The TGF-β superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev. 8, 133-146.
-
(1994)
Genes Dev.
, vol.8
, pp. 133-146
-
-
Kingsley, D.M.1
-
28
-
-
0031010944
-
Recognition of AUG and alternative initiator codons is augmented by G in position +4 but is not generally affected by the nucleotides in positions +5 and +6
-
Kozak, M. (1997) Recognition of AUG and alternative initiator codons is augmented by G in position +4 but is not generally affected by the nucleotides in positions +5 and +6. EMBO J. 16, 2482-2492.
-
(1997)
EMBO J.
, vol.16
, pp. 2482-2492
-
-
Kozak, M.1
-
29
-
-
0026743899
-
Promoter-specific trans-activation by the adenovirus E1A12S product involves separate E1A domains
-
Kraus, V.B., Moran, E. & Nevins, J.R. (1992) Promoter-specific trans-activation by the adenovirus E1A12S product involves separate E1A domains. Mol. Cell. Biol. 12, 4391-4399.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 4391-4399
-
-
Kraus, V.B.1
Moran, E.2
Nevins, J.R.3
-
30
-
-
0030911104
-
The TGF-β family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase
-
Kretzschmar, M., Liu, F., Hata, A., Doody, J. & Massagué, J. (1997) The TGF-β family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase. Genes Dev. 11, 984-995.
-
(1997)
Genes Dev.
, vol.11
, pp. 984-995
-
-
Kretzschmar, M.1
Liu, F.2
Hata, A.3
Doody, J.4
Massagué, J.5
-
31
-
-
0029834067
-
Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways
-
Lagna, G., Hata, A., Hemmati-Brivanlou, A. & Massagué, J. (1996) Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways. Nature 383, 832-836.
-
(1996)
Nature
, vol.383
, pp. 832-836
-
-
Lagna, G.1
Hata, A.2
Hemmati-Brivanlou, A.3
Massagué, J.4
-
32
-
-
0029931509
-
A human Mad protein acting as a BMP-regulated transcriptional activator
-
Liu, F., Hata, A., Baker, J.C., et al. (1996) A human Mad protein acting as a BMP-regulated transcriptional activator. Nature 381, 620-623.
-
(1996)
Nature
, vol.381
, pp. 620-623
-
-
Liu, F.1
Hata, A.2
Baker, J.C.3
-
33
-
-
0030690337
-
Dual role of the Smad4/DPC4 tumor suppressor in TGFβ-inducible transcriptional complexes
-
Liu, F., Pouponnot, C. & Massagué, J. (1997) Dual role of the Smad4/DPC4 tumor suppressor in TGFβ-inducible transcriptional complexes. Genes Dev. 11, 3157-3167.
-
(1997)
Genes Dev.
, vol.11
, pp. 3157-3167
-
-
Liu, F.1
Pouponnot, C.2
Massagué, J.3
-
34
-
-
0032481351
-
The L3 loop: A structural motif determining specific interactions between SMAD proteins and TGF-β receptors
-
Lo, R.S., Chen, Y.-G., Shi, Y., Pavletich, N.P. & Massagué, J. (1998) The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-β receptors. EMBO J. 17, 996-1005.
-
(1998)
EMBO J.
, vol.17
, pp. 996-1005
-
-
Lo, R.S.1
Chen, Y.-G.2
Shi, Y.3
Pavletich, N.P.4
Massagué, J.5
-
35
-
-
0028985162
-
Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional coactivator CBP
-
Lundblad, J.R., Kwok, R.P., Laurance, M.E., Harter, M.L. & Goodman, R.H. (1995) Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional coactivator CBP. Nature 374, 85-88.
-
(1995)
Nature
, vol.374
, pp. 85-88
-
-
Lundblad, J.R.1
Kwok, R.P.2
Laurance, M.E.3
Harter, M.L.4
Goodman, R.H.5
-
36
-
-
0030300115
-
MADR2 is a substrate of the TGFβ receptor and its phosphorylation is required for nuclear accumulation and signaling
-
Macías-Silva, M., Abdollah, S., Hoodless, P.A., Pirone, R., Attisano, L. & Wrana, J.L. (1996) MADR2 is a substrate of the TGFβ receptor and its phosphorylation is required for nuclear accumulation and signaling. Cell 87, 1215-1224.
-
(1996)
Cell
, vol.87
, pp. 1215-1224
-
-
Macías-Silva, M.1
Abdollah, S.2
Hoodless, P.A.3
Pirone, R.4
Attisano, L.5
Wrana, J.L.6
-
37
-
-
0026323942
-
Induction of transforming growth factor β1 resistance by the E1A oncogene requires binding to a specific set of cellular proteins
-
Missero, C., Filvaroff, E. & Dotto, G.P. (1991) Induction of transforming growth factor β1 resistance by the E1A oncogene requires binding to a specific set of cellular proteins. Proc. Natl. Acad. Sci. USA 88, 3489-3493.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 3489-3493
-
-
Missero, C.1
Filvaroff, E.2
Dotto, G.P.3
-
38
-
-
0032499789
-
Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members
-
Moustakas, A. & Kardassis, D. (1998) Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members. Proc. Natl. Acad. Sci. USA 95, 6733-6738.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6733-6738
-
-
Moustakas, A.1
Kardassis, D.2
-
39
-
-
0030611757
-
Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling
-
Nakao, A., Afrakhte, M., Morén, A., et al. (1997) Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling. Nature 389, 631-635.
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
Afrakhte, M.2
Morén, A.3
-
40
-
-
0025348820
-
TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains
-
Pietenpol, J.A., Stein, R.W., Moran, E., et al. (1990) TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell 61, 777-785.
-
(1990)
Cell
, vol.61
, pp. 777-785
-
-
Pietenpol, J.A.1
Stein, R.W.2
Moran, E.3
-
41
-
-
0000116653
-
The transforming growth factor-βs
-
(eds M.B. Sporn & A.B. Roberts) Heidelberg: Springer-Verlag
-
Roberts, A.B. & Sporn, M.B. (1990) The transforming growth factor-βs. In: Peptide Growth Factors and Their Receptors (eds M.B. Sporn & A.B. Roberts) Part I, pp. 419-472. Heidelberg: Springer-Verlag.
-
(1990)
Peptide Growth Factors and Their Receptors
, Issue.1 PART
, pp. 419-472
-
-
Roberts, A.B.1
Sporn, M.B.2
-
42
-
-
0028940853
-
Genetic characterization and cloning of Mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster
-
Sekelsky, J.J., Newfeld, S.J., Raftery, L.A., Chartoff, E.H. & Gelbart, W.M. (1995) Genetic characterization and cloning of Mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics 139, 1347-1358.
-
(1995)
Genetics
, vol.139
, pp. 1347-1358
-
-
Sekelsky, J.J.1
Newfeld, S.J.2
Raftery, L.A.3
Chartoff, E.H.4
Gelbart, W.M.5
-
44
-
-
0032030770
-
Histone acetylation and transcriptional regulatory mechanisms
-
Struhl, K. (1998) Histone acetylation and transcriptional regulatory mechanisms. Genes Dev. 12, 599-606.
-
(1998)
Genes Dev.
, vol.12
, pp. 599-606
-
-
Struhl, K.1
-
45
-
-
0032489280
-
Induction of Smad6 mRNA by bone morphogenetic proteins
-
Takase, M., Imamura, T., Sampath, T.K., et al. (1998) Induction of Smad6 mRNA by bone morphogenetic proteins. Biochem. Biophys. Res. Commun. 244, 26-29.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.244
, pp. 26-29
-
-
Takase, M.1
Imamura, T.2
Sampath, T.K.3
-
46
-
-
0030863365
-
Daughters against dpp modulates dpp organizing activity in Drosophila wing development
-
Tsuneizumi, K., Nakayama, T., Kamoshida, Y., Kornberg, T.B., Christian, J.L. & Tabata, T. (1997) Daughters against dpp modulates dpp organizing activity in Drosophila wing development. Nature 389, 627-631.
-
(1997)
Nature
, vol.389
, pp. 627-631
-
-
Tsuneizumi, K.1
Nakayama, T.2
Kamoshida, Y.3
Kornberg, T.B.4
Christian, J.L.5
Tabata, T.6
-
47
-
-
0029022221
-
GS domain mutations that constitutively activate TβR-I, the downstream signaling component in the TGF-β receptor complex
-
Wieser, R., Wrana, J.L. & Massagué, J. (1995) GS domain mutations that constitutively activate TβR-I, the downstream signaling component in the TGF-β receptor complex. EMBO J. 14, 2199-2208.
-
(1995)
EMBO J.
, vol.14
, pp. 2199-2208
-
-
Wieser, R.1
Wrana, J.L.2
Massagué, J.3
-
48
-
-
0030697971
-
Tumor suppressor Smad4 is a transforming growth factor β-inducible DNA binding protein
-
Yingling, J.M., Datto, M.B., Wong, C., Frederick, J.P., Liberati, N.T. & Wang, X.-F. (1997) Tumor suppressor Smad4 is a transforming growth factor β-inducible DNA binding protein. Mol. Cell. Biol. 17, 7019-7028.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 7019-7028
-
-
Yingling, J.M.1
Datto, M.B.2
Wong, C.3
Frederick, J.P.4
Liberati, N.T.5
Wang, X.-F.6
-
49
-
-
0032014216
-
Human Smad3 and Smad4 are sequence-specific transcription activators
-
Zawel, L., Dai, J.L., Buckhaults, P., et al. (1998) Human Smad3 and Smad4 are sequence-specific transcription activators. Mol. Cell 1, 611-617.
-
(1998)
Mol. Cell
, vol.1
, pp. 611-617
-
-
Zawel, L.1
Dai, J.L.2
Buckhaults, P.3
-
50
-
-
0029786212
-
Receptor-associated Mad homologues synergize as effectors of the TGF-β response
-
Zhang, Y., Feng, X.-H., Wu, R.-Y. & Derynck, R. (1996) Receptor-associated Mad homologues synergize as effectors of the TGF-β response. Nature 383, 168-172.
-
(1996)
Nature
, vol.383
, pp. 168-172
-
-
Zhang, Y.1
Feng, X.-H.2
Wu, R.-Y.3
Derynck, R.4
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