TGF-β1 induces the cyclin-dependent kinase inhibitor p27(Kip1) mRNA and protein in murine B cells

Journal of Immunology

Volumn 160, Issue 2, 1998, Pages 770-777

  Kamesaki, Hiroshi ^a   Nishizawa, Kimiko ^a   Michaud, Ginette Y ^b   Cossman, Jeffrey ^b   Kiyono, Tohru ^a  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; MESSENGER RNA; PROTEIN P27; PROTEIN P53; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL CYCLE; CONTROLLED STUDY; ENZYME ACTIVITY; EPITHELIUM CELL; GENE CONTROL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY;

ANIMALS; B-LYMPHOCYTES; CARRIER PROTEINS; CDC2-CDC28 KINASES; CELL CYCLE PROTEINS; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P15; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; CYCLINS; ENZYME ACTIVATION; LYMPHOMA, B-CELL; MICE; MICROTUBULE-ASSOCIATED PROTEINS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 0031975911     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Moses, H., E. Y. Yang, and J. A. Pietenpol. 1990. TGF-β stimulation and inhibition of cell proliferation: new mechanistic insights. Cell 63:245.
2. Massague, J. A. 1990. The transforming growth factor-β family. Annu. Rev. Cell Biol. 6:597.
3. Sporn, M. B., and A. B. Roberts. 1992. Transforming growth factor-β: recent progress and new challenges. J. Cell Biol. 119:1017.
4. 1 cyclins. Cell 73:1059.
5. Hunter, T. 1993. Braking the cycle. Cell 75:839.
6. 1 kinase activity for cdk6, a novel cyclin D partner. Mol. Cell. Biol. 14:2077.
7. Ewen, M. E., H. K. Sluss, L. L. Whitehouse, and D. M. Livingston. 1993. TGF-β inhibition of cdk4 synthesis is linked to cell cycle arrest. Cell 74:1009.
8. 1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-β. Science 260:536.
9. INK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature 371:257.
10. INK4b genes. Oncogene 11:635.
11. 1 arrest. Cell 76:1013.
12. El-Deiry, W. S., T. Tokino, V. E. Velculescu, D. B. Levy, R. Parsons, J. M. Trent, D. Lin, W. E. Mercer, K. W. Kinzler, and B. Vogelstein. 1993. WAF1, a potential mediator of p53 tumor suppression. Cell 75:817.
13. 1 cyclin-dependent kinases. Cell 75:805.
14. Xiong, Y., G. J. Hannon, H. Zhang, D. Casso, R. Kobayashi, and D. Beach. 1993. p21 is a universal inhibitor of cyclin kinases. Nature 366:701.
15. Xiong, Y., H. Zhang, and D. Beach. 1993. Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation. Genes Dev. 7:1572.
16. Zhang, H., G. J. Hannon, and D. Beach. 1994. p21-containing cyclin kinases exist in both active and inactive states. Genes Dev. 8:1750.
17. Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev. 8:9.
18. Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78:59.
19. Toyoshima, H., and T. Hunter. 1994. p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78:67.
20. Reynisdottir, I., K. Polyak, A. Iavarone, and J. Massague. 1995. Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β. Genes Dev. 9:1831.
21. Elbendary, A., A. Berchuck, P. Davis, L. Havrilesky, R. C. Bast, Jr., J. D. Iglehart, and J. R. Marks. 1994. Transforming growth factor β1 can induce CIP1/WAF1 expression independent of the p53 pathway in ovarian cancer cells. Cell Growth Differ. 3:291.
22. Datto, M. B., Y. Li, J. F. Panus, D. J. Howe, Y. Xiong, and X-F. Wang. 1995. Transforming growth factor β induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. Proc. Natl. Acad. Sci. USA 92:5545.
23. Li, C-Y., L. Suardet, and J. B. Little. 1995. Potential role of WAF1/Cip1/p21 as a mediator of TGF-β cytoinhibitory effect. J. Biol. Chem. 270:4971.
24. Lane, D. P., and S. Benchimol. 1990. p53: oncogene or anti-oncogene. Genes Dev. 4:1.
25. Kastan, M. B., Q. Zhan, W. S. El-Deiry, F. Carrier, T. Jacks, W. V. Walsh, B. S. Plunkett, B. Vogelstein, and A. J. Fornace, Jr. 1992. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxiatelangiectasia. Cell 71:587.
26. 1 in murine keratinocytes. Cancer Res. 53:899.
27. 1 in nasopharyngeal carcinoma cells transduced with adenovirus early region genes. Jpn. J. Cancer Res. 85:459.
28. 1 cell-cycle arrest. Genes Dev. 9:204.
29. Warner, G. L., J. W. Ludlow, D. A. Nelson, A. Gaur, and D. W. Scott. 1992. Anti-immunoglobulin treatment of murine B-cell lymphomas induces active transforming growth factor β, but pRB hypophosphorylation is transforming growth factor β independent. Cell Growth Differ. 3:175.
30. Pennel, C. A., L. W. Arnold, P. M. Lutz., N. J. LoCascio, P. B. Willoughby, and G. Haughton. 1985. Cross-reactive idiotypes and common antigen binding specificities expressed by a series of murine B-cell lymphomas: etiological implications Proc. Natl. Acad. Sci. USA 82:3799.
31. Diegel, M. L., B. M. Rankin, J. B. Bolen, P. M. Dubois, and P. A. Kiener. 1994. Cross-linking of Fcγ receptor to surface immunoglobulin on B cells provides an inhibitory signal that closes the plasma membrane calcium channel. J. Biol. Chem. 269:11409.
32. Boukamp, P., R. T. Petrussevska, D. Breitkreutz, J. Hornung, A. Markham, and N. E. Fusenig. 1988. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J. Cell Biol. 106:761.
33. Sato, H., T. Tsukada, M. Nagayoshi, Y. Ikawa, S. Aizawa, and M. V. Kato. 1995. Repression of p53-dependent sequence-specific transactivation by MEF2c. Biochem. Biophys. Res. Commun. 214:468.
34. Kamesaki, H., J. A. Zwiebel, J. C. Reed, and J. Cossman. 1994. Role of bcl-2 and IL-5 in the regulation of anti-IgM-induced growth arrest and apoptosis in immature B cell lines. J. Immunol. 152:3294.
35. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156.
36. Ohno, H., S. Fukuhara, Y. Arita, S. Doi, R. Takahashi, H. Fujii, T. Honjo, T. Sugiyama, and H. Uchino. 1988. Establishment of a peripheral T-cell lymphoma cell line showing amplication of the c-myc oncogene. Cancer Res. 48:4959.
37. Maltzman, W., M. Oren, and A. J. Levine. 1981. The structural relationships between 54,000-molecular-weight cellular tumor antigens detected in viral- and nonviral-transformed cells. Virology 112:145.
38. Kiyono, T., A. Hiraiwa, S. Ishii, T. Takahashi, and M. Ishibashi. 1994. Inhibition of p53-mediated transactivation by E6 of type 1, but not type 5, 8, or 47, human papillomavirus of cutaneous origin. J. Virol. 68:4656.
39. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl. 1994. Transfection of DNA into eukaryotic cells: calcium phosphate transfection. In Current Protocols in Molecular Biology. Greene Publishing Associates and Wiley-Interscience, New York, p. 9.1.1.
40. Russo, T., N. Zambrano, F. Esposito, R. Ammendola, F. Cimino, M. Fiscella, J. Jackman, P. M. O'Connor, C. W. Anderson, and E. Appella. 1995. A p53-independent pathway for activation of WAF1/CIP1 expression following oxidative stress. J. Biol. Chem. 270:29386.
41. WAF1/CIP1 expression by p53-independent pathways. Oncogene 12:1557.
42. Kulkarni, P. S., K. Sundqvist, C. Betsholtz, P. Hoglund, K. G. Wiman, B. Zhivotovsky, F. Bertolero, Y. Liu., and R. C. Grafstrom. 1995. Characterization of human buccal epithelial cells transfected with the simian virus 40 T-antigen gene. Carcinogenesis 16:2515.
43. Soussi, T., C. Caron de Fromentel, and P. May. 1990. Structural aspects of p53 protein in relation to gene evolution. Oncogene 5:945.
44. 1 arrest and apoptosis. Cancer Res. 54:1169.
45. Zhan, Q., S. Fan, I. Bae, C. Guillouf, D. A. Liebermann, P. M. O'Connor, and A. J. Fornace, Jr. 1994. Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis. Oncogene 9:3743.