Transforming growth factor-β-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines

Journal of Biological Chemistry

Volumn 274, Issue 49, 1999, Pages 35053-35058

  Rich, Jeremy N ^a   Zhang, Ming ^a   Datto, Michael B ^a   Bigner, Darell D ^a   Wang, Xiao Fan ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENIC FACTOR; CYCLIN DEPENDENT KINASE INHIBITOR; DNA; PROTEIN; PROTEIN P15; RETINOBLASTOMA PROTEIN; SCLEROPROTEIN; THYMIDINE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; ASTROCYTE; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVITY; GENE; GLIOMA CELL; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TRANSCRIPTION REGULATION;

ANIMALS; ASTROCYTES; BLOTTING, SOUTHERN; BLOTTING, WESTERN; CARRIER PROTEINS; CDC2-CDC28 KINASES; CELL CYCLE PROTEINS; CELL DIVISION; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P15; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; CYCLINS; DNA-BINDING PROTEINS; FLOW CYTOMETRY; G1 PHASE; GLIOMA; HUMANS; MICE; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RATS; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0033521118     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.49.35053     Document Type: Article

References (48)

1. Massague, J. (1996) Cell 85, 947-950
2. Hannon, G. J., and Beach, D. (1994) Nature 371, 257-260
3. Flanders, K. C., Ren, R. F., and Lippa, C. F. (1998) Prog. Neurobiol. (N. Y.) 54, 71-85
4. Toru-Delbauffe, D., Baghdassarian-Chalaye, D., Gavaret, J. M., Courtin, F., Pomerance, M., and Pierre, M. (1990) J. Neurochem. 54, 1056-1061
5. Vergelli, M., Mazzanti, B., Ballerini, C., Gran, B., Amaducci, L., and Massacesi, L. (1995) J. Neurosci. Res. 40, 127-133
6. Chang, H.-L., Gillett, N., Figari, I., Lopez, A. R., Palladino, M. A., and Derynck, R. (1993) Cancer Res. 53, 4391-4398
7. Cui, W., Fowlis, D. J., Bryson, S., Duffie, E., Ireland, H., Balmain, A., and Akhurst, R. J. (1996) Cell 86, 531-542
8. Weller, M., and Fontana, A. (1995) Brain Res. Rev. 21, 128-151
9. Behzadian, M. A., Wang, X.-L., Shabrawey, M., and Caldwell, R. B. (1998) Glia 24, 216-225
10. Merzak, A., McCrea, S., Koocheckpour, S., and Pilkington, G. J. (1994) Br. J. Cancer 70, 199-203
11. Paulus, W., Baur, I., Huettner, C., Schmauber, B., Roggendorf, W., Schlingensiepen, K.-H., and Brysch, W. (1995) J. Neuropathol. Exp. Neurol. 54, 236-244
12. Jennings, M. T., and Pietenpol, J. A. (1998) J. Neuro-oncol. 36, 123-140
13. Constam, D. B., Philipp, J., Malipiero, U. V., Ten Dijke, P., Schachner, M., and Fontana, A. (1992) J. Immunol. 148, 1404-1410
14. Stiles, J. D., Ostrow, P. T., Balos, L. L., Greenberg, S. J., Plunkett, R., Grand, W., and Heffner, R. R. (1997) J. Neuropathol. Exp. Neurol. 56, 435-439
15. Fakhrai, H., Dorigo, O., Shawler, D. L., Lin, H., Mercola, D., Black, K. L., Royston, I., and Sobol, R. E. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 2909-2914
16. Liau, L. M., Fakhrai, H., and Black, K. L. (1998) Neurol. Res. 20, 742-747
17. Helseth, E., Unsgaard, G., Dalen, A., and Randi, V. (1988) J Neuro-oncol. 6, 269-276
18. Helseth, E., Unsgaard, G., Dalen, A., and Randi, V. (1988) Cancer Immunol. Immunother. 26, 273-279
19. Jachimczak, P., Hessdorfer, B., Faebel-Schulte, K., Wismeth, C., Brysch, W., Schlingensiepen, K.-H., Bauer, A., Blesch, A., and Bogdahn, U. (1996) Int. J. Cancer 65, 332-337
20. Jennings, M. T., Maciunas, R. J., Carver, R., Bascom, C. C., Juneau, P., Misulius, K., and Moses, H. L. (1991) Int. J. Cancer 49, 129-139
21. Marushige, K., and Marushige, Y. (1994) Anticancer Res. 14, 2419-2424
22. Barnett, S. (1994) in Culture of Animal Cells (Freshney, R. I., ed) 2nd Ed., pp. 337-349, Wiley-Liss, Inc., New York
23. Vick, W. W., Wikstrand, C. J., Bullard, D. E., Kemshead, J., Coakham, H. B., Schlom, J., Johnston, W. W., Bigner, D. D., and Bigner, S. H. (1987) Acta Cytol. 31, 815-824
24. Datto, M. B., Li, Y., Panus, J. F., Howe, D. J., Xiong, Y., and Wang, X.-F. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 5545-5549
25. Herman, J. G., Jen, J., Merlo, A., and Baylin S. B. (1996) Cancer Res. 56, 722-727
26. Wrana, J. L., Attisano, L., Carcamo, J., Zentella, A., Doody, J., Laiho, M., Wang, X.-F., and Massague, J. (1992) Cell 71, 1003-1014
27. Moustakas, A., and Kardassis, D. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6733-6738
28. Datto, M. B., Frederick, J. P., Pan, L., Borton, A. J., Zhaung, Y., and Wang, X.-F. (1999) Mol. Cell. Biol. 19, 2495-2504
29. Izumoto, S., Arita, N., Oshnishi, T., Hiraga, S., Taki, T., Tomita, N., Ohue, M., and Hayakawa, T. (1997) Cancer Lett. 112, 251-256
30. Kalkhoven, E., Roelen, B. A., de Winter, J. P., Mummery, C. L., van den Eijnden-van Raaij, A. J., van der Saag, P. T., and van der Burg, B. (1995) Cell Growth Differ. 6, 1151-1161
31. Sun, L., Wu, G., Willson, J. K., Zborowska, E., Yang, J., Rajkarunanayake, I., Wang, J., Gentry, L. E., Wang, X.-F., and Brattain, M. G. (1994) J. Biol. Chem. 269, 26449-26455
32. Riggins, G. J., Kinzler, K. W., Vogelstein, B., and Thiagalingam, S. (1997) Cancer Res. 57, 2578-2580
33. Sun, P., Dong, P., Dai, K., Hannon, G. J., and Beach, D. (1998) Science 282, 2270-2272
34. Alexandrow, M. G., Kawabata, M., Aakre, M., and Moses, H. L. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 3239-3243
35. Feng, X. H., Zhang, Y., Wu, R. Y., and Derynck, R. (1998) Genes Dev. 12, 2153-2163
36. Shen, X., Hu, P. P., Liberati, N. T., Datto, M. B., Frederick, J. P., and Wang, X.-F. (1998) Mol. Biol. Cell 9, 3309-3319
37. Chen, R.-H., Ebner, R., and Derynck, R. (1993) Science 260, 1335-1338
38. Isoe, S., Naganuma, H., Nakano, S., Sasaki, A., Satoh, E., Nagasaka, M., Maeda, S., and Nukui, H. (1998) J. Neurosurg. 88, 529-534
39. Laiho, M., Ronnstrand, L., Heino, J., Decaprio, J. A., Ludlow, J. W., Livingston, D. M., and Massague, J. (1991) Mol. Cell. Biol. 11, 972-978
40. Piek, E., Westermark, U., Kastemar, M., Heldin, C.-H., van Zoelen, E. J., Nister, M., and Ten Dijke, P. (1999) Int. J. Cancer 80, 756-763
41. Jen, J., Harper, J. W., Bigner, S. H., Bigner, D. D., Papadopoulous, N., Markowitz, S., Willson, J. K. V., Kinzler, K. W., and Vogelstein, B. (1994) Cancer Res. 54, 6353-6358
42. Sonoda, Y., Yoshimoto, T., and Sekiya, T. (1995) Oncogene 11, 2145-2149
43. Tenan, M., Benedetti, S., and Finocchiaro, G. (1995) Biochem. Biophys. Res. Commun. 217, 195-202
44. Zhang, S., Endo, S., Koga, H., Ichikawa, T., Feng, X., Onda, K., Washiyama, K., and Kumanishi, T. (1996) Jpn. J. Cancer Res. 87, 900-907
45. Arap, W., Knudsen, E., Sewell, D. A., Sidransky, D., Wang, J. Y. J., Huang, J. S., and Cavenee, W. K. (1997) Oncogene 15, 2013-2020
46. Bindal, A. K., Hammoud, M., Shi, W. M., Wu, S. Z., Sawaya, R., and Rao, J. S. (1994) J. Neuro-oncol. 22, 101-110
47. Reuning, U., Magdolen, V., Wilhelm, O., Fischer, K., Lutz, V., Graeff, H., and Schmitt, M. (1998) Int. J. Oncol. 13, 893-906
48. Samoto, K., Ikezaki, K., Ono, M., Shono, T., Kohno, K., Kuwano, M., and Fukui, M. (1995) Cancer Res. 55, 1189-1193