메뉴 건너뛰기




Volumn 18, Issue 5, 1998, Pages 307-320

Recent advances in the understanding of interleukin-2 signal transduction

Author keywords

Interleukin 2; Signal transduction

Indexed keywords

ADAPTOR PROTEIN; COMPLEMENTARY DNA; CYTOKINE; CYTOKINE RECEPTOR; FAS ANTIGEN; FAS LIGAND; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GROWTH FACTOR; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; TYROSINE;

EID: 0031694552     PISSN: 02719142     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1023223614407     Document Type: Article
Times cited : (63)

References (123)
  • 1
    • 0017199306 scopus 로고
    • Selective in vitro growth of T lymphocytes from normal human hone marrows
    • Morgan DA, Ruscetti FW, Gullo R: Selective in vitro growth of T lymphocytes from normal human hone marrows. Science 193:1007-1008, 1976
    • (1976) Science , vol.193 , pp. 1007-1008
    • Morgan, D.A.1    Ruscetti, F.W.2    Gullo, R.3
  • 3
    • 0029863903 scopus 로고    scopus 로고
    • Fas and the art of lymphocyte maintenance
    • Lenardo MJ: Fas and the art of lymphocyte maintenance. J Exp Med 183:721-724, 1996
    • (1996) J Exp Med , vol.183 , pp. 721-724
    • Lenardo, M.J.1
  • 5
    • 0023907493 scopus 로고
    • Interleukin-2: Inception, impact, and implications
    • Smith KA: Interleukin-2: inception, impact, and implications. Science 240:1169-1176, 1988
    • (1988) Science , vol.240 , pp. 1169-1176
    • Smith, K.A.1
  • 6
    • 0025102756 scopus 로고
    • Haemopoietic receptors and helical cytokines
    • Bazan JF: Haemopoietic receptors and helical cytokines. Immunol Today 11:350-354, 1990
    • (1990) Immunol Today , vol.11 , pp. 350-354
    • Bazan, J.F.1
  • 7
    • 0028122050 scopus 로고
    • Cytokine receptors: A combinative family of molecules
    • Theze J: Cytokine receptors: a combinative family of molecules. Eur Cytokine Netw 5:353-368, 1994
    • (1994) Eur Cytokine Netw , vol.5 , pp. 353-368
    • Theze, J.1
  • 9
    • 0028332867 scopus 로고
    • The cytoplasmic domain of the interleukin-2 receptor β chain contains both unique and functionally redundant signal transduction elements
    • Goldsmith MA, Xu W, Amaral MC, Kuczek ES, Greene WC: The cytoplasmic domain of the interleukin-2 receptor β chain contains both unique and functionally redundant signal transduction elements. J Biol Chem 269:14698-14704, 1994
    • (1994) J Biol Chem , vol.269 , pp. 14698-14704
    • Goldsmith, M.A.1    Xu, W.2    Amaral, M.C.3    Kuczek, E.S.4    Greene, W.C.5
  • 10
    • 0029124056 scopus 로고
    • Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the β chain and non-tyrosine residues of the γ c chain
    • Goldsmith MA, Lai SY, Xu W, Amaral MC, Kuczek ES, Parent LJ, Mills GB, Tarr KL, Longmore GD, Greene WC: Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the β chain and non-tyrosine residues of the γ c chain. J Biol Chem 270:21729-21737, 1995
    • (1995) J Biol Chem , vol.270 , pp. 21729-21737
    • Goldsmith, M.A.1    Lai, S.Y.2    Xu, W.3    Amaral, M.C.4    Kuczek, E.S.5    Parent, L.J.6    Mills, G.B.7    Tarr, K.L.8    Longmore, G.D.9    Greene, W.C.10
  • 12
    • 0023884930 scopus 로고
    • Activation of a tyrosine protein kinase is an early event in the stimulation of T lymphocytes by interleukin-2
    • Saltzman EM, Thom RR, Casnellie JE: Activation of a tyrosine protein kinase is an early event in the stimulation of T lymphocytes by interleukin-2. J Biol Chem 263:6956-6959, 1988
    • (1988) J Biol Chem , vol.263 , pp. 6956-6959
    • Saltzman, E.M.1    Thom, R.R.2    Casnellie, J.E.3
  • 14
    • 0028286628 scopus 로고
    • Cytoplasmic domains of the interleukin-2 receptor β and γ chains mediate the signal for T-cell proliferation
    • Nelson BH, Lord JD Greenberg PD: Cytoplasmic domains of the interleukin-2 receptor β and γ chains mediate the signal for T-cell proliferation. Nature 369:333-336, 1994
    • (1994) Nature , vol.369 , pp. 333-336
    • Nelson, B.H.1    Lord, J.D.2    Greenberg, P.D.3
  • 15
    • 0025848163 scopus 로고
    • Interaction of the IL-2 receptor with the src-family kinase p56lck: Identification of novel intermolecular association
    • Hatakeyama M, Kono T, Kobayashi N, Kawahara A, Levin SD, Perlmutter RM, Taniguchi T: Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association. Science 252:1523-1528, 1991
    • (1991) Science , vol.252 , pp. 1523-1528
    • Hatakeyama, M.1    Kono, T.2    Kobayashi, N.3    Kawahara, A.4    Levin, S.D.5    Perlmutter, R.M.6    Taniguchi, T.7
  • 16
    • 0027393848 scopus 로고
    • Association of p56lck with IL-2 receptor β chain is critical for the IL-2-induced activation of p56lck
    • Minami Y, Kono T, Yamada K, Kobayashi N, Kawahara A, Perlmutter RM, Taniguchi T: Association of p56lck with IL-2 receptor β chain is critical for the IL-2-induced activation of p56lck. EMBO J 12:759-768, 1993
    • (1993) EMBO J , vol.12 , pp. 759-768
    • Minami, Y.1    Kono, T.2    Yamada, K.3    Kobayashi, N.4    Kawahara, A.5    Perlmutter, R.M.6    Taniguchi, T.7
  • 17
    • 0027278222 scopus 로고
    • Functional coupling of the src-family protein tyrosine kinases p59fyn and p53/56lyn with the interleukin 2 receptor: Implications for redundancy and pleiotropism in cytokine signal transduction
    • Kobayashi N Kono T, Hatakeyama M, Minami Y, Miyazaki T, Perlmutter RM, Taniguchi T: Functional coupling of the src-family protein tyrosine kinases p59fyn and p53/56lyn with the interleukin 2 receptor: Implications for redundancy and pleiotropism in cytokine signal transduction. Proc Natl Acad Sci USA 90:4201-4205, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4201-4205
    • Kobayashi, N.1    Kono, T.2    Hatakeyama, M.3    Minami, Y.4    Miyazaki, T.5    Perlmutter, R.M.6    Taniguchi, T.7
  • 18
    • 0028988329 scopus 로고
    • Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: Possible link with the c-myc induction pathway
    • Minami Y, Nakagawa Y, Kawahara A, Miyazaki T, Sada K, Yamamura H, Taniguchi T: Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway. Immunity 2:89-100, 1995
    • (1995) Immunity , vol.2 , pp. 89-100
    • Minami, Y.1    Nakagawa, Y.2    Kawahara, A.3    Miyazaki, T.4    Sada, K.5    Yamamura, H.6    Taniguchi, T.7
  • 20
    • 0026632288 scopus 로고
    • A protein tyrosine kinase in the interferon α/β signaling pathway
    • Velazquez, L, Fellous M, Stark GR, Pellegrini S: A protein tyrosine kinase in the interferon α/β signaling pathway. Cell 70:313-322, 1992
    • (1992) Cell , vol.70 , pp. 313-322
    • Velazquez, L.1    Fellous, M.2    Stark, G.R.3    Pellegrini, S.4
  • 22
    • 0029834676 scopus 로고    scopus 로고
    • Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome
    • Zhang Q, Nowak I, Vonderheid EC, Rook AH, Kadin ME, Nowell PC, Shaw LM, Wasik MA: Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome. Proc Natl Acad Sci USA 93:9148-9153, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9148-9153
    • Zhang, Q.1    Nowak, I.2    Vonderheid, E.C.3    Rook, A.H.4    Kadin, M.E.5    Nowell, P.C.6    Shaw, L.M.7    Wasik, M.A.8
  • 25
    • 0029115353 scopus 로고
    • Critical role of the interleukin 2 (IL-2) receptor γ-chain- Associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction
    • Kawahara A, Minami Y, Miyazaki T, Ihle JN, Taniguchi T: Critical role of the interleukin 2 (IL-2) receptor γ-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction. Proc Natl Acad Sci USA 92:8724-8728, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8724-8728
    • Kawahara, A.1    Minami, Y.2    Miyazaki, T.3    Ihle, J.N.4    Taniguchi, T.5
  • 27
    • 0029011115 scopus 로고
    • The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor β c chain
    • Zhao Y, Wagner F, Frank SJ, Kraft AS: The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor β c chain. J Biol Chem 270:13814-13818, 1995
    • (1995) J Biol Chem , vol.270 , pp. 13814-13818
    • Zhao, Y.1    Wagner, F.2    Frank, S.J.3    Kraft, A.S.4
  • 28
    • 0031009816 scopus 로고    scopus 로고
    • The amino terminus of JAK3 is necessary and sufficient for binding to the common y chain and confers the ability to transmit interleukin 2-mediated signals
    • Chen M, Cheng A, Chen YQ, Hymel A, Hanson EP, Kimmel L, Minami Y, Taniguchi T, Changelian PS, JJ OS: The amino terminus of JAK3 is necessary and sufficient for binding to the common y chain and confers the ability to transmit interleukin 2-mediated signals. Proc Natl Acad Sci USA 94:6910-6915, 1997
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6910-6915
    • Chen, M.1    Cheng, A.2    Chen, Y.Q.3    Hymel, A.4    Hanson, E.P.5    Kimmel, L.6    Minami, Y.7    Taniguchi, T.8    Changelian, P.S.9    Jj, O.S.10
  • 31
    • 0026028846 scopus 로고
    • T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p56lck
    • Horak ID, Gress RE, Lucas PJ, Horak EM, Waldmann TA, Bolen JB: T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p56lck. Proc Natl Acad Sci USA 88:1996-2000, 1991
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 1996-2000
    • Horak, I.D.1    Gress, R.E.2    Lucas, P.J.3    Horak, E.M.4    Waldmann, T.A.5    Bolen, J.B.6
  • 32
    • 0025177324 scopus 로고
    • Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases
    • Ellis C, Moran M, McCormick F, Pawson T: Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases. Nature 343:377-381, 1990
    • (1990) Nature , vol.343 , pp. 377-381
    • Ellis, C.1    Moran, M.2    McCormick, F.3    Pawson, T.4
  • 33
    • 0026551141 scopus 로고
    • Ras GTPase-activating protein: A substrate and a potential binding protein of the protein-tyrosine kinase p56lck
    • Amrein KE, Flint N, Panholzer B, Burn P: Ras GTPase-activating protein: A substrate and a potential binding protein of the protein-tyrosine kinase p56lck. Proc Natl Acad Sci USA 89: 3343-3346, 1992
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3343-3346
    • Amrein, K.E.1    Flint, N.2    Panholzer, B.3    Burn, P.4
  • 34
    • 0028984220 scopus 로고
    • p70 phosphorylation and binding to p56lck is an early event in interleukin-2-induced onset of cell cycle progression in T-lymphocytes
    • Vogel LB, Fujita DJ: p70 phosphorylation and binding to p56lck is an early event in interleukin-2-induced onset of cell cycle progression in T-lymphocytes. J Biol Chem 270:2506-2511, 1995
    • (1995) J Biol Chem , vol.270 , pp. 2506-2511
    • Vogel, L.B.1    Fujita, D.J.2
  • 35
    • 0026611039 scopus 로고
    • Effects of p56lck deficiency on the growth and cytolytic effector function of an interleukin-2-dependent cytotoxic T-cell line
    • Karnitz L, Sutor SL, Torigoe T, Reed JC, Bell MP, McKean DJ, Leibson PJ, Abraham RT: Effects of p56lck deficiency on the growth and cytolytic effector function of an interleukin-2-dependent cytotoxic T-cell line. Mol Cell Biol 12:4521-4530, 1992
    • (1992) Mol Cell Biol , vol.12 , pp. 4521-4530
    • Karnitz, L.1    Sutor, S.L.2    Torigoe, T.3    Reed, J.C.4    Bell, M.P.5    McKean, D.J.6    Leibson, P.J.7    Abraham, R.T.8
  • 36
    • 0026564442 scopus 로고
    • Neither the LCK nor the FYN kinases are obligatory for IL-2-mediated signal transduction in HTLV-I-infected human T cells
    • Mills GB, Arima N, May C, Hill M, Schmandt R, Li J, Miyamoto NG, Greene WC: Neither the LCK nor the FYN kinases are obligatory for IL-2-mediated signal transduction in HTLV-I-infected human T cells. Int Immunol 4:1233-1243, 1992
    • (1992) Int Immunol , vol.4 , pp. 1233-1243
    • Mills, G.B.1    Arima, N.2    May, C.3    Hill, M.4    Schmandt, R.5    Li, J.6    Miyamoto, N.G.7    Greene, W.C.8
  • 37
    • 0028014460 scopus 로고
    • Signal transduction by lymphocyte antigen receptors
    • Weiss A, Littman DR: Signal transduction by lymphocyte antigen receptors. Cell 76:263-274, 1994
    • (1994) Cell , vol.76 , pp. 263-274
    • Weiss, A.1    Littman, D.R.2
  • 38
    • 0030499383 scopus 로고    scopus 로고
    • Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product
    • Deckert M, Tartare-Deckert S, Couture C, Mustelin T, Altman A: Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product. Immunity 5:591-604, 1996
    • (1996) Immunity , vol.5 , pp. 591-604
    • Deckert, M.1    Tartare-Deckert, S.2    Couture, C.3    Mustelin, T.4    Altman, A.5
  • 39
    • 0027170719 scopus 로고
    • Interleukin-2 induces tyrosine phosphorylation of the vav proto- Oncogene product in human T cells: Lack of requirement for the tyrosine kinase lck
    • Evans GA, Howard OM, Erwin R, Farrar WL: Interleukin-2 induces tyrosine phosphorylation of the vav proto-oncogene product in human T cells: Lack of requirement for the tyrosine kinase lck. Biochem J 294:339-342, 1993
    • (1993) Biochem J , vol.294 , pp. 339-342
    • Evans, G.A.1    Howard, O.M.2    Erwin, R.3    Farrar, W.L.4
  • 40
    • 0025273347 scopus 로고
    • Interleukin 2 (IL-2)-induced tyrosine phosphorylation of IL-2 receptor p75
    • Asao H, Takeshita T, Nakamura M, Nagata K, Sugamura K: Interleukin 2 (IL-2)-induced tyrosine phosphorylation of IL-2 receptor p75. J Exp Med 171:637-644, 1990
    • (1990) J Exp Med , vol.171 , pp. 637-644
    • Asao, H.1    Takeshita, T.2    Nakamura, M.3    Nagata, K.4    Sugamura, K.5
  • 41
    • 0026643440 scopus 로고
    • IL-2-dependent in vivo and in vitro tyrosine phosphorylation of IL-2 receptor y chain
    • Asao H, Kumaki S, Takeshita T, Nakamura M, Sugamura K: IL-2-dependent in vivo and in vitro tyrosine phosphorylation of IL-2 receptor y chain. FEBS Lett 304:141-145, 1992
    • (1992) FEBS Lett , vol.304 , pp. 141-145
    • Asao, H.1    Kumaki, S.2    Takeshita, T.3    Nakamura, M.4    Sugamura, K.5
  • 42
    • 0029875230 scopus 로고    scopus 로고
    • Different interleukin 2 receptor β-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation
    • Friedmann MC, Migone TS, Russell SM, Leonard WJ: Different interleukin 2 receptor β-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation. Proc Natl Acad Sci USA 93:2077-2082, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2077-2082
    • Friedmann, M.C.1    Migone, T.S.2    Russell, S.M.3    Leonard, W.J.4
  • 44
    • 0029813118 scopus 로고    scopus 로고
    • Distinct tyrosine residues within the interleukin-2 receptor β chain drive signal transduction specificity, redundancy, and diversity
    • Gaffen SL, Lai SY, Ha M, Liu X, Hennighausen L, Greene WC, Goldsmith MA: Distinct tyrosine residues within the interleukin-2 receptor β chain drive signal transduction specificity, redundancy, and diversity. J Biol Chem 271:21381-21390, 1996
    • (1996) J Biol Chem , vol.271 , pp. 21381-21390
    • Gaffen, S.L.1    Lai, S.Y.2    Ha, M.3    Liu, X.4    Hennighausen, L.5    Greene, W.C.6    Goldsmith, M.A.7
  • 45
    • 0029046208 scopus 로고
    • Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor β chain but is not essential for the proliferative signal transmission
    • Fujii H, Nakagawa Y, Schindler U, Kawahara A, Mori H, Gouilleux F, Groner B, Ihle JN, Minami Y, Miyazaki T, et al.: Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor β chain but is not essential for the proliferative signal transmission. Proc Natl Acad Sci USA 92:5482-5486, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5482-5486
    • Fujii, H.1    Nakagawa, Y.2    Schindler, U.3    Kawahara, A.4    Mori, H.5    Gouilleux, F.6    Groner, B.7    Ihle, J.N.8    Minami, Y.9    Miyazaki, T.10
  • 46
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell JE Jr, Kerr IM, Stark GR: Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264:1415-1421, 1994
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell Jr., J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 47
    • 0028819828 scopus 로고
    • Interleukin 2 activates STAT5 transcription factor (mammary gland factor) and specific gene expression in T lymphocytes
    • Gilmour KC, Pine R, Reich NC: Interleukin 2 activates STAT5 transcription factor (mammary gland factor) and specific gene expression in T lymphocytes. Proc Natl Acad Sci USA 92:10772-10776, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 10772-10776
    • Gilmour, K.C.1    Pine, R.2    Reich, N.C.3
  • 49
    • 0028596154 scopus 로고
    • Interleukin-2 induces tyrosine phosphorylation and nuclear translocation of stat3 in human T lymphocytes
    • Nielsen M, Svejgaard A, Skov S, Odum N: Interleukin-2 induces tyrosine phosphorylation and nuclear translocation of stat3 in human T lymphocytes. Bur J Immunol 24:3082-3086, 1994
    • (1994) Bur J Immunol , vol.24 , pp. 3082-3086
    • Nielsen, M.1    Svejgaard, A.2    Skov, S.3    Odum, N.4
  • 50
    • 0029936611 scopus 로고    scopus 로고
    • Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway
    • Beadling C, Ng J, Babbage JW, Cantrell DA: Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway. EMBO J 15:1902-1913, 1996
    • (1996) EMBO J , vol.15 , pp. 1902-1913
    • Beadling, C.1    Ng, J.2    Babbage, J.W.3    Cantrell, D.A.4
  • 51
    • 0029117304 scopus 로고
    • Maximal activation of transcription by Stat1 and Stat3 requires both lyrosine and serine phosphorylation
    • Wen Z, Zhong Z, Darnell JE Jr: Maximal activation of transcription by Stat1 and Stat3 requires both lyrosine and serine phosphorylation. Cell 82:241-250, 1995
    • (1995) Cell , vol.82 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell Jr., J.E.3
  • 52
    • 0030919149 scopus 로고    scopus 로고
    • Two discrete regions of interleukin-2 (IL2) receptor β independently mediate IL2 activation of a PD98059/rapamycin/wortmannin-insensitive Stat5a/b serine kinase
    • Kirken RA, Malabarba MG, Xu J, DaSilva L, Erwin RA, Liu X, Hennighausen L, Rui H, Farrar WL: Two discrete regions of interleukin-2 (IL2) receptor β independently mediate IL2 activation of a PD98059/rapamycin/wortmannin-insensitive Stat5a/b serine kinase. J Biol Chem 272:15459-15465, 1997
    • (1997) J Biol Chem , vol.272 , pp. 15459-15465
    • Kirken, R.A.1    Malabarba, M.G.2    Xu, J.3    Dasilva, L.4    Erwin, R.A.5    Liu, X.6    Hennighausen, L.7    Rui, H.8    Farrar, W.L.9
  • 54
  • 55
    • 0029853971 scopus 로고    scopus 로고
    • An IL-2 response element in the human IL-2 receptor α chain promoter is a composite element that hinds Stat5, Elf-1, HMG-I(Y) and a GATa family protein
    • John S, Robbins CM, Leonard WJ: An IL-2 response element in the human IL-2 receptor α chain promoter is a composite element that hinds Stat5, Elf-1, HMG-I(Y) and a GATA family protein. EMBO J 15:5627-5635, 1996
    • (1996) EMBO J , vol.15 , pp. 5627-5635
    • John, S.1    Robbins, C.M.2    Leonard, W.J.3
  • 56
    • 0029909493 scopus 로고    scopus 로고
    • Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor α gene
    • Lecine P, Algarte M, Rameil P, Beadling C, Bucher P, Nabholz, M, Imbert J: Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor α gene. Mol Cell Biol 16:6829-6840, 1996
    • (1996) Mol Cell Biol , vol.16 , pp. 6829-6840
    • Lecine, P.1    Algarte, M.2    Rameil, P.3    Beadling, C.4    Bucher, P.5    Nabholz, M.6    Imbert, J.7
  • 57
    • 0029892399 scopus 로고    scopus 로고
    • Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: Role of Stat5 in proliferation
    • Mui AL, Wakao H, Kinoshita T, Kitamura T, Miyajima A: Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: Role of Stat5 in proliferation. EMBO J 15:2425-2433, 1996
    • (1996) EMBO J , vol.15 , pp. 2425-2433
    • Mui, A.L.1    Wakao, H.2    Kinoshita, T.3    Kitamura, T.4    Miyajima, A.5
  • 58
    • 0024297307 scopus 로고
    • Regulation of pim and myb mRNA accumulation by interleukin 2 and interleukin 3 in murine hematopoietic cell lines
    • Dautry F, Weil D, Yu J, Dautry-Varsat A: Regulation of pim and myb mRNA accumulation by interleukin 2 and interleukin 3 in murine hematopoietic cell lines. J Biol Chem 263:17615-17620, 1988
    • (1988) J Biol Chem , vol.263 , pp. 17615-17620
    • Dautry, F.1    Weil, D.2    Yu, J.3    Dautry-Varsat, A.4
  • 59
    • 0029014206 scopus 로고
    • A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors
    • Yoshimura A, Ohkubo T, Kiguchi T, Jenkins NA, Gilbert DJ, Copeland NG, Hara T, Miyajima A: A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors. EMBO J 14:2816-2826, 1995
    • (1995) EMBO J , vol.14 , pp. 2816-2826
    • Yoshimura, A.1    Ohkubo, T.2    Kiguchi, T.3    Jenkins, N.A.4    Gilbert, D.J.5    Copeland, N.G.6    Hara, T.7    Miyajima, A.8
  • 60
    • 0030930196 scopus 로고    scopus 로고
    • STAT5A-deficient mice demonstrate a defect in granulocyte-macrophage colony-stimulating factor-induced proliferation and gene expression
    • Feldman GM, Rosenthal LA, Liu X, Hayes MP, Wynshaw-Boris A, Leonard WJ, Hennighausen L, Finbloom DS: STAT5A-deficient mice demonstrate a defect in granulocyte-macrophage colony-stimulating factor-induced proliferation and gene expression. Blood 90:1768-1776, 1997
    • (1997) Blood , vol.90 , pp. 1768-1776
    • Feldman, G.M.1    Rosenthal, L.A.2    Liu, X.3    Hayes, M.P.4    Wynshaw-Boris, A.5    Leonard, W.J.6    Hennighausen, L.7    Finbloom, D.S.8
  • 63
    • 0031473350 scopus 로고    scopus 로고
    • Cytokine-inducible signaling inhibitors
    • Aman MJ, Leonard WJ: Cytokine-inducible signaling inhibitors. Curr Biol 7:784-788, 1997
    • (1997) Curr Biol , vol.7 , pp. 784-788
    • Aman, M.J.1    Leonard, W.J.2
  • 64
    • 0024376173 scopus 로고
    • ras oncogenes in human cancer: A review
    • Bos JL: ras oncogenes in human cancer: A review. Cancer Res 49:4682-4689, 1989
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 65
    • 0027948205 scopus 로고
    • Induction of apoptosis by a dominant negative H-RAS mutant (116Y) in K562 cells
    • Sakai N, Ogiso Y, Fujita H, Watari H, Koike T, Kuzumaki N: Induction of apoptosis by a dominant negative H-RAS mutant (116Y) in K562 cells. Exp Cell Res 215:131-136, 1994
    • (1994) Exp Cell Res , vol.215 , pp. 131-136
    • Sakai, N.1    Ogiso, Y.2    Fujita, H.3    Watari, H.4    Koike, T.5    Kuzumaki, N.6
  • 66
    • 0029033866 scopus 로고
    • Regulation of Bcl-2 expression by oncogenic Ras protein in hematopoietic cells
    • Kinoshita T, Yokota T, Arai K, Miyajima A: Regulation of Bcl-2 expression by oncogenic Ras protein in hematopoietic cells. Oncogene 10:2207-2212, 1995
    • (1995) Oncogene , vol.10 , pp. 2207-2212
    • Kinoshita, T.1    Yokota, T.2    Arai, K.3    Miyajima, A.4
  • 67
    • 0028971751 scopus 로고
    • Direction of p21ras-generated signals towards cell growth or apoptosis is determined by protein kinase C and Bcl-2
    • Chen CY, Faller DV: Direction of p21ras-generated signals towards cell growth or apoptosis is determined by protein kinase C and Bcl-2. Oncogene 11:1487-1498, 1995
    • (1995) Oncogene , vol.11 , pp. 1487-1498
    • Chen, C.Y.1    Faller, D.V.2
  • 69
    • 0026483357 scopus 로고
    • Function of Ras as a molecular switch in signal transduction
    • Satoh T, Nakafuku M, Kaziro Y: Function of Ras as a molecular switch in signal transduction. J Biol Chem 267:24149-24152, 1992
    • (1992) J Biol Chem , vol.267 , pp. 24149-24152
    • Satoh, T.1    Nakafuku, M.2    Kaziro, Y.3
  • 70
    • 0028142436 scopus 로고
    • Interleukin-2-induced tyrosine phosphorylation of She proteins correlates with factor-dependent T cell proliferation
    • Zhu X, Suen KL, Barbacid M, Bolen JB, Fargnoli J: Interleukin-2-induced tyrosine phosphorylation of She proteins correlates with factor-dependent T cell proliferation. J Biol Chem 269: 5518-5522, 1994
    • (1994) J Biol Chem , vol.269 , pp. 5518-5522
    • Zhu, X.1    Suen, K.L.2    Barbacid, M.3    Bolen, J.B.4    Fargnoli, J.5
  • 71
    • 0027955433 scopus 로고
    • The adapter protein She interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation
    • Ravichandran KS, Burakoff SJ: The adapter protein She interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation. J Biol Chem 269:1599-1602, 1994
    • (1994) J Biol Chem , vol.269 , pp. 1599-1602
    • Ravichandran, K.S.1    Burakoff, S.J.2
  • 72
    • 0028792221 scopus 로고
    • Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require She phosphorylation or receptor association
    • Evans GA, Goldsmith MA, Johnston JA, Xu W, Weiler SR, Erwin R, Howard OM, Abraham RT, JJ OS, Greene WC, et al.: Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require She phosphorylation or receptor association. J Biol Chem 270:28858-28863, 1995
    • (1995) J Biol Chem , vol.270 , pp. 28858-28863
    • Evans, G.A.1    Goldsmith, M.A.2    Johnston, J.A.3    Xu, W.4    Weiler, S.R.5    Erwin, R.6    Howard, O.M.7    Abraham, R.T.8    Jj, O.S.9    Greene, W.C.10
  • 73
    • 0026480756 scopus 로고
    • Interleukin 2-induced activation of Ras requires two domains of interleukin 2 receptor β subunit, the essential region for growth stimulation and Lck-hinding domain
    • Satoh T, Minami Y, Kono T, Yamada K, Kawahara A, Taniguchi T, Kaziro Y: Interleukin 2-induced activation of Ras requires two domains of interleukin 2 receptor β subunit, the essential region for growth stimulation and Lck-hinding domain. J Biol Chem 267:25423-25427, 1992
    • (1992) J Biol Chem , vol.267 , pp. 25423-25427
    • Satoh, T.1    Minami, Y.2    Kono, T.3    Yamada, K.4    Kawahara, A.5    Taniguchi, T.6    Kaziro, Y.7
  • 74
    • 0027321461 scopus 로고
    • Interleukin 2 activates extracellular signal-regulated protein kinase 2
    • Perkins GR, Marvel J, Collins MK: Interleukin 2 activates extracellular signal-regulated protein kinase 2. J Exp Med 178: 1429-1434, 1993
    • (1993) J Exp Med , vol.178 , pp. 1429-1434
    • Perkins, G.R.1    Marvel, J.2    Collins, M.K.3
  • 76
    • 0030903693 scopus 로고    scopus 로고
    • T cell proliferation in response to interleukins 2 and 7 requires p38MAP kinase activation
    • Crawley JB, Rawlinson L, Lali FV, Page TH, Saklatvala J, Foxwell BM: T cell proliferation in response to interleukins 2 and 7 requires p38MAP kinase activation. J Biol Chem 272:15023-15027, 1997
    • (1997) J Biol Chem , vol.272 , pp. 15023-15027
    • Crawley, J.B.1    Rawlinson, L.2    Lali, F.V.3    Page, T.H.4    Saklatvala, J.5    Foxwell, B.M.6
  • 77
    • 0025788098 scopus 로고
    • Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73
    • Smeal T, Binetruy B, Mercola DA, Birrer M, Karin M: Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73. Nature 354:494-196, 1991
    • (1991) Nature , vol.354 , pp. 494-1196
    • Smeal, T.1    Binetruy, B.2    Mercola, D.A.3    Birrer, M.4    Karin, M.5
  • 78
    • 0025806587 scopus 로고
    • Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain
    • Binetruy B, Smeal T, Karin M: Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. Nature 351:122-127, 1991
    • (1991) Nature , vol.351 , pp. 122-127
    • Binetruy, B.1    Smeal, T.2    Karin, M.3
  • 79
    • 0028486018 scopus 로고
    • Phosphatidylinositol 3-kinase
    • Kapeller R, Cantley LC: Phosphatidylinositol 3-kinase. Bioessays 16:565-576, 1994
    • (1994) Bioessays , vol.16 , pp. 565-576
    • Kapeller, R.1    Cantley, L.C.2
  • 81
    • 0029913340 scopus 로고    scopus 로고
    • Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain
    • Antonetti DA, Algenstaedt P, Kahn CR: Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain. Mol Cell Biol 16:2195-2203, 1996
    • (1996) Mol Cell Biol , vol.16 , pp. 2195-2203
    • Antonetti, D.A.1    Algenstaedt, P.2    Kahn, C.R.3
  • 83
    • 0026486879 scopus 로고
    • Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 β protein by using the baculovirus expression system
    • Gout I, Dhand R, Panayotou G, Fry MJ, Hiles I, Otsu M, Waterfield MD: Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 β protein by using the baculovirus expression system. Biochem J 288:395-405, 1992
    • (1992) Biochem J , vol.288 , pp. 395-405
    • Gout, I.1    Dhand, R.2    Panayotou, G.3    Fry, M.J.4    Hiles, I.5    Otsu, M.6    Waterfield, M.D.7
  • 85
    • 0025784441 scopus 로고
    • Interleukin 2- and polyomavirus middle T antigen-induced modification of phosphatidylinositol 3-kinase activity in activated T lymphocytes
    • Augustine JA, Sutor SL, Abraham RT: Interleukin 2-and polyomavirus middle T antigen-induced modification of phosphatidylinositol 3-kinase activity in activated T lymphocytes. Mol Cell Biol 11:4431-4440, 1991
    • (1991) Mol Cell Biol , vol.11 , pp. 4431-4440
    • Augustine, J.A.1    Sutor, S.L.2    Abraham, R.T.3
  • 86
    • 0026091203 scopus 로고
    • IL-2 binding activates a tyrosine-phosphorylated phosphatidylinositol-3- Kinase
    • Merida I, Diez E, Gaulton GN: IL-2 binding activates a tyrosine-phosphorylated phosphatidylinositol-3-kinase. J Immunol 147: 2202-2207, 1991
    • (1991) J Immunol , vol.147 , pp. 2202-2207
    • Merida, I.1    Diez, E.2    Gaulton, G.N.3
  • 87
    • 0030293886 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/ Rho-dependent effector pathways
    • Reif K, Nobes CD, Thomas G, Hall A, Cantrell DA: Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/ Rho-dependent effector pathways. Curr Biol 6:1445-1455, 1996
    • (1996) Curr Biol , vol.6 , pp. 1445-1455
    • Reif, K.1    Nobes, C.D.2    Thomas, G.3    Hall, A.4    Cantrell, D.A.5
  • 88
    • 0027333338 scopus 로고
    • The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3′-kinase from T lymphocytes
    • Vogel LB, Fujita DJ: The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3′-kinase from T lymphocytes. Mol Cell Biol 13:7408-7417, 1993
    • (1993) Mol Cell Biol , vol.13 , pp. 7408-7417
    • Vogel, L.B.1    Fujita, D.J.2
  • 89
    • 0027218948 scopus 로고
    • Evidence that protein tyrosine kinase p56-Lck regulates the activity of phosphatidylinositol-3′-kinase in interleukin-2-dependent T-cells
    • Taichman R, Merida I, Torigoe T, Gaulton GN, Reed JC: Evidence that protein tyrosine kinase p56-Lck regulates the activity of phosphatidylinositol-3′-kinase in interleukin-2-dependent T-cells. J Biol Chem 268:20031-20036, 1993
    • (1993) J Biol Chem , vol.268 , pp. 20031-20036
    • Taichman, R.1    Merida, I.2    Torigoe, T.3    Gaulton, G.N.4    Reed, J.C.5
  • 90
    • 0028122142 scopus 로고
    • Serine-rich region of the IL-2 receptor β-chain is required for activation of phosphatidylinositol 3-kinase
    • Kanazawa T, Keeler ML, Varticovski L: Serine-rich region of the IL-2 receptor β-chain is required for activation of phosphatidylinositol 3-kinase. Cell Immunol 156:378-388, 1994
    • (1994) Cell Immunol , vol.156 , pp. 378-388
    • Kanazawa, T.1    Keeler, M.L.2    Varticovski, L.3
  • 91
    • 0028108278 scopus 로고
    • SH2-dependent association of phosphatidylinositol 3′-kinase 85-kDa regulatory subunit with the interleukin-2 receptor βchain
    • Truitt KE, Mills GB, Turck CW, Imboden JB: SH2-dependent association of phosphatidylinositol 3′-kinase 85-kDa regulatory subunit with the interleukin-2 receptor βchain. J Biol Chem 269:5937-5943, 1994
    • (1994) J Biol Chem , vol.269 , pp. 5937-5943
    • Truitt, K.E.1    Mills, G.B.2    Turck, C.W.3    Imboden, J.B.4
  • 92
    • 0028908804 scopus 로고
    • Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinosilol 3-kinase and inhibited by cyclic AMP
    • Monfar M, Lemon KP, Grammer TC, Cheatham L, Chung J, Vlahos CJ, Blenis J: Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinosilol 3-kinase and inhibited by cyclic AMP. Mol Cell Biol 15:326-337, 1995
    • (1995) Mol Cell Biol , vol.15 , pp. 326-337
    • Monfar, M.1    Lemon, K.P.2    Grammer, T.C.3    Cheatham, L.4    Chung, J.5    Vlahos, C.J.6    Blenis, J.7
  • 93
    • 0030908525 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase
    • Reif K, Burgering BM, Cantrell DA: Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase. J Biol Chem 272:14426-14433, 1997
    • (1997) J Biol Chem , vol.272 , pp. 14426-14433
    • Reif, K.1    Burgering, B.M.2    Cantrell, D.A.3
  • 94
    • 0030890933 scopus 로고    scopus 로고
    • Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase
    • Ahmed NN, Grimes HL, Bellacosa A, Chan TO, Tsichlis PN: Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc Natl Acad Sci USA 94:3627-3632, 1997
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3627-3632
    • Ahmed, N.N.1    Grimes, H.L.2    Bellacosa, A.3    Chan, T.O.4    Tsichlis, P.N.5
  • 95
    • 0342820096 scopus 로고    scopus 로고
    • Intermediate affinity interleukin-2 receptor mediates survival via a phosphatidylinositol 3-kinase-dependent pathway
    • Gonzalez-Garcia A, Merida I, Martinez AC, Carrera AC: Intermediate affinity interleukin-2 receptor mediates survival via a phosphatidylinositol 3-kinase-dependent pathway. J Biol Chem 272:10220-10226, 1997
    • (1997) J Biol Chem , vol.272 , pp. 10220-10226
    • Gonzalez-Garcia, A.1    Merida, I.2    Martinez, A.C.3    Carrera, A.C.4
  • 96
    • 0029811866 scopus 로고    scopus 로고
    • Association of phosphatidylinositol 3 kinase to protein kinase C zeta during interleukin-2 stimulation
    • Gomez J, Martinez C, Garcia A, Rebollo A: Association of phosphatidylinositol 3 kinase to protein kinase C zeta during interleukin-2 stimulation. Eur J Immunol 26:1781-1787, 1996
    • (1996) Eur J Immunol , vol.26 , pp. 1781-1787
    • Gomez, J.1    Martinez, C.2    Garcia, A.3    Rebollo, A.4
  • 98
    • 0030744134 scopus 로고    scopus 로고
    • Role of phosphatases in lymphocyte activation
    • Neel BG: Role of phosphatases in lymphocyte activation. Curr Opin Immunol 9:405-420, 1997
    • (1997) Curr Opin Immunol , vol.9 , pp. 405-420
    • Neel, B.G.1
  • 99
    • 0031150017 scopus 로고    scopus 로고
    • The role of phosphotyrosine phosphatases in haematopoietic cell signal transduction
    • Frearson JA, Alexander DR: The role of phosphotyrosine phosphatases in haematopoietic cell signal transduction. Bioessays 19:417-427, 1997
    • (1997) Bioessays , vol.19 , pp. 417-427
    • Frearson, J.A.1    Alexander, D.R.2
  • 100
    • 0024416009 scopus 로고
    • Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation
    • Pingel JT, Thomas ML: Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation. Cell 58:1055-1065, 1989
    • (1989) Cell , vol.58 , pp. 1055-1065
    • Pingel, J.T.1    Thomas, M.L.2
  • 101
    • 0027197067 scopus 로고
    • Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene
    • Shultz LD, Schweitzer PA, Rajan TV, Yi T, Ihle JN, Matthews RJ, Thomas ML, Beier DR: Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene. Cell 73:1445-1454, 1993
    • (1993) Cell , vol.73 , pp. 1445-1454
    • Shultz, L.D.1    Schweitzer, P.A.2    Rajan, T.V.3    Yi, T.4    Ihle, J.N.5    Matthews, R.J.6    Thomas, M.L.7    Beier, D.R.8
  • 102
    • 0028136280 scopus 로고
    • Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin
    • Milarski KL, Saltiel AR: Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin. J Biol Chem 269:21239-21243, 1994
    • (1994) J Biol Chem , vol.269 , pp. 21239-21243
    • Milarski, K.L.1    Saltiel, A.R.2
  • 103
    • 0030049783 scopus 로고    scopus 로고
    • Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression
    • Bennett AM, Hausdorff SF, AM OR, Freeman RM, Neel BG: Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression. Mol Cell Biol 16:1189-1202, 1996
    • (1996) Mol Cell Biol , vol.16 , pp. 1189-1202
    • Bennett, A.M.1    Hausdorff, S.F.2    Am, O.R.3    Freeman, R.M.4    Neel, B.G.5
  • 105
    • 0031055524 scopus 로고    scopus 로고
    • Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor γ(c) chain for Janus kinase activation leading to T cell proliferation
    • Nelson BH, McIntosh BC, Rosencrans LL, Greenberg PD: Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor γ(c) chain for Janus kinase activation leading to T cell proliferation. Proc Natl Acad Sci USA 94:1878-1883, 1997
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 1878-1883
    • Nelson, B.H.1    McIntosh, B.C.2    Rosencrans, L.L.3    Greenberg, P.D.4
  • 106
    • 0028953283 scopus 로고
    • Involvement of SH2-containing phosphotyrosine phosphatase Syp in erythropoietin receptor signal transduction pathways
    • Tauchi T, Feng GS, Shen R, Hoatlin M, Bagby GC Jr, Kabat D, Lu L, Broxmeyer HE: Involvement of SH2-containing phosphotyrosine phosphatase Syp in erythropoietin receptor signal transduction pathways. J Biol Chem 270:5631-5635, 1995
    • (1995) J Biol Chem , vol.270 , pp. 5631-5635
    • Tauchi, T.1    Feng, G.S.2    Shen, R.3    Hoatlin, M.4    Bagby Jr., G.C.5    Kabat, D.6    Lu, L.7    Broxmeyer, H.E.8
  • 107
    • 0029145460 scopus 로고
    • IL-2-induced gene expression of protein-tyrosine phosphatase LC-PTP requires acidic and serine-rich regions within IL-2 receptor β chain
    • Adachi M, Torigoe T, Sekiya M, Minami Y, Taniguchi T, Hinoda Y, Yachi A, Reed JC, Imai K: IL-2-induced gene expression of protein-tyrosine phosphatase LC-PTP requires acidic and serine-rich regions within IL-2 receptor β chain. FEBS Lett 372:113-118, 1995
    • (1995) FEBS Lett , vol.372 , pp. 113-118
    • Adachi, M.1    Torigoe, T.2    Sekiya, M.3    Minami, Y.4    Taniguchi, T.5    Hinoda, Y.6    Yachi, A.7    Reed, J.C.8    Imai, K.9
  • 108
    • 17044444647 scopus 로고    scopus 로고
    • STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction
    • Takeshita T, Arita T, Higuchi M, Asao H, Endo K, Kuroda H, Tanaka N, Murata K, Ishii N, Sugamura K: STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction. Immunity 6:449-457, 1997
    • (1997) Immunity , vol.6 , pp. 449-457
    • Takeshita, T.1    Arita, T.2    Higuchi, M.3    Asao, H.4    Endo, K.5    Kuroda, H.6    Tanaka, N.7    Murata, K.8    Ishii, N.9    Sugamura, K.10
  • 109
    • 0032512824 scopus 로고    scopus 로고
    • Interleukin-2 stimulation induces tyrosine phosphorylation of p120-Cbl and CrkL and formation of multimolecular signaling complexes in T lymphocytes and natural killer cells
    • Gesbert F, Garbay C, Bertoglio J: Interleukin-2 stimulation induces tyrosine phosphorylation of p120-Cbl and CrkL and formation of multimolecular signaling complexes in T lymphocytes and natural killer cells. J Biol Chem 273:3986-3993, 1998
    • (1998) J Biol Chem , vol.273 , pp. 3986-3993
    • Gesbert, F.1    Garbay, C.2    Bertoglio, J.3
  • 110
    • 0024593048 scopus 로고
    • v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas
    • Langdon WY, Hartley JW, Klinken SP, Ruscetti SK, Morse HCd: v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas. Proc Natl Acad Sci USA 86:1168-1172, 1989
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1168-1172
    • Langdon, W.Y.1    Hartley, J.W.2    Klinken, S.P.3    Ruscetti, S.K.4    Morse, H.Cd.5
  • 111
    • 0025819499 scopus 로고
    • The sequences of the human and mouse c-cbl proto-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif
    • Blake TJ, Shapiro M, Morse HCd, Langdon WY: The sequences of the human and mouse c-cbl proto-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif. Oncogene 6:653-657, 1991
    • (1991) Oncogene , vol.6 , pp. 653-657
    • Blake, T.J.1    Shapiro, M.2    Morse, H.Cd.3    Langdon, W.Y.4
  • 112
    • 0023864050 scopus 로고
    • A novel viral oncogene with structural similarity to phospholipase C
    • Mayer BJ, Hamaguchi M, Hanafusa H: A novel viral oncogene with structural similarity to phospholipase C. Nature 332:272-275, 1988
    • (1988) Nature , vol.332 , pp. 272-275
    • Mayer, B.J.1    Hamaguchi, M.2    Hanafusa, H.3
  • 113
    • 0026686182 scopus 로고
    • Two species of human CRK cDNA encode proteins with distinct biological activities
    • Matsuda M, Tanaka S, Nagata S, Kojima A, Kurata T, Shibuya M: Two species of human CRK cDNA encode proteins with distinct biological activities. Mol Cell Biol 12:3482-3489, 1992
    • (1992) Mol Cell Biol , vol.12 , pp. 3482-3489
    • Matsuda, M.1    Tanaka, S.2    Nagata, S.3    Kojima, A.4    Kurata, T.5    Shibuya, M.6
  • 114
    • 0027179910 scopus 로고
    • Isolation and chromosomal localization of CRKL. A human crk-like gene
    • ten Hoeve J, Morris C, Heisterkamp N, Groffen J: Isolation and chromosomal localization of CRKL. a human crk-like gene. Oncogene 8:2469-2474, 1993
    • (1993) Oncogene , vol.8 , pp. 2469-2474
    • Ten Hoeve, J.1    Morris, C.2    Heisterkamp, N.3    Groffen, J.4
  • 116
    • 0030999238 scopus 로고    scopus 로고
    • Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit. phosphatidylinositol 3-kinase, and p120(CBL)
    • Sattler M, Salgia R, Shrikhande G, Verma S, Pisick E, Prasad KV, Griffin JD: Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit. phosphatidylinositol 3-kinase, and p120(CBL). J Biol Chem 272:10248-10253, 1997
    • (1997) J Biol Chem , vol.272 , pp. 10248-10253
    • Sattler, M.1    Salgia, R.2    Shrikhande, G.3    Verma, S.4    Pisick, E.5    Prasad, K.V.6    Griffin, J.D.7
  • 117
    • 0029876948 scopus 로고    scopus 로고
    • Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G
    • Reedquist KA, Fukazawa T, Panchamoorthy G, Langdon WY, Shoelson SE, Druker BJ, Band H: Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G. J Biol Chem 271: 8435-8442, 1996
    • (1996) J Biol Chem , vol.271 , pp. 8435-8442
    • Reedquist, K.A.1    Fukazawa, T.2    Panchamoorthy, G.3    Langdon, W.Y.4    Shoelson, S.E.5    Druker, B.J.6    Band, H.7
  • 118
    • 0030611712 scopus 로고    scopus 로고
    • Differential signaling after β1 integrin ligation is mediated through binding of CRKL to p120(CBL) and p110(HEF1)
    • Sattler M, Salgia R, Shrikhande G, Verma S, Uemura N, Law SF, Golemis EA, Griffin JD: Differential signaling after β1 integrin ligation is mediated through binding of CRKL to p120(CBL) and p110(HEF1). J Biol Chem 272:14320-14326, 1997
    • (1997) J Biol Chem , vol.272 , pp. 14320-14326
    • Sattler, M.1    Salgia, R.2    Shrikhande, G.3    Verma, S.4    Uemura, N.5    Law, S.F.6    Golemis, E.A.7    Griffin, J.D.8
  • 119
    • 0030889218 scopus 로고    scopus 로고
    • The product of the proto-oncogene c-cbl: A negative regulator of the Syk tyrosine kinase
    • Ota Y, Samelson LE: The product of the proto-oncogene c-cbl: A negative regulator of the Syk tyrosine kinase. Science 276:418-420, 1997
    • (1997) Science , vol.276 , pp. 418-420
    • Ota, Y.1    Samelson, L.E.2
  • 122
    • 0030903027 scopus 로고    scopus 로고
    • Human immune disorder arising from mutation of the a chain of the interleukin-2 receptor
    • Sharfe N, Dadi HK, Shahar M, Roifman CM: Human immune disorder arising from mutation of the a chain of the interleukin-2 receptor. Proc Natl Acad Sci USA 94:3168-3171, 1997
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3168-3171
    • Sharfe, N.1    Dadi, H.K.2    Shahar, M.3    Roifman, C.M.4
  • 123
    • 0031433335 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F
    • Brennan P, Babbage JW, Burgering BM, Groner B, Reif K, Cantrell DA: Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F. Immunity 7:679-689, 1997
    • (1997) Immunity , vol.7 , pp. 679-689
    • Brennan, P.1    Babbage, J.W.2    Burgering, B.M.3    Groner, B.4    Reif, K.5    Cantrell, D.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.