Transcription factors as targets for DNA-interacting drugs

Current Medicinal Chemistry

Volumn 10, Issue 11, 2003, Pages 909-924

  Gniazdowski, Marek ^a   Denny, William A ^b   Nelson, Stephanie M ^b   Czyz, Malgorzata ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Anticancer drugs; Antigene oligonucleotides; DNA protein interactions; Transcription factors

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ACRIDINE DERIVATIVE; ALKYLATING AGENT; ANTHRACYCLINE DERIVATIVE; ANTHRAMYCIN; ANTINEOPLASTIC AGENT; CHLORMETHINE; CHROMOMYCIN; CISPLATIN; CONGOCIDINE; DACTINOMYCIN; DAUNORUBICIN; DISTAMYCIN A; DOXORUBICIN; HEDAMYCIN; HOE 33342; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MEPACRINE; MITHRAMYCIN; NOGALAMYCIN; OLIGONUCLEOTIDE; PEPTIDE NUCLEIC ACID; POLYAMIDE; PYRROLE DERIVATIVE; REGULATOR PROTEIN; TALLIMUSTINE; TILORONE; TRANSCRIPTION FACTOR; TRANSPLATIN; UNINDEXED DRUG;

DNA ALKYLATION; DNA DRUG COMPLEX; DNA SEQUENCE; DRUG BINDING SITE; DRUG COMPETITION; DRUG DNA INTERACTION; DRUG STRUCTURE; DRUG TARGETING; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; PROTEIN DNA INTERACTION; REGULATORY MECHANISM; REVIEW; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, ALKYLATING; DNA; DRUG DELIVERY SYSTEMS; DRUG DESIGN; HUMANS; INTERCALATING AGENTS; OLIGONUCLEOTIDES, ANTISENSE; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS;

EID: 0037648966     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867033457683     Document Type: Review

References (176)

1. Goldberg, I.H.; Reich, E.; Rabinowitz, M. Nature, 1963, 199, 44.
2. Lindell, T.J. In Inhibitors of DNA and RNA Polymerases; Sarin, P.S.; Gallo, R.C. Eds.; Pergamon Press: Oxford, 1980; pp. 111-137.
3. Krakow, J.S.; Kumar, S.A. In Inhibitors of DNA and RNA Polymerases; Sarin, P.S.; Gallo, R.C. Eds.; Pergamon Press: Oxford, 1980; pp.139-157.
4. Müller, W.E.G. In Inhibitors of DNA and RNA Polymerases; Sarin, P.S.; Gallo, R.C. Eds.; Pergamon Press: Oxford, 1980; pp. 207-224.
5. Hahn, F.E. In Inhibitors of DNA and RNA Polymerases; Sarin, P.S.; Gallo, R.C. Eds.; Pergamon Press: Oxford, 1980; pp. 225-234.
6. Gale, E.F.; Cundliffe, E.; Reynolds, P.E.; Richmond, M.H.; Waring, M.J. In The Molecular Basis of Antibiotic Action; Wiley, N.Y., 1981; pp. 258-401.
7. Denny, W.A. Anti-Cancer Drug Design, 1989, 4, 241.
8. Baguley, B.C. Anti-Cancer Drug Design, 1991, 6, 1.
9. Brana, M.F.; Cacho, M.; Gradillas, A,; de Pasqual-Teresa, B.; Ramos, A. Curr. Pharm. Des., 2001, 7, 1745.
10. Gniazdowski, M.; Tomasz, M. Curr. Pneumol., 1999, 3, 1.
11. Gniazdowski, M.; Cera, C. Chem. Rev., 1996, 96, 619.
12. Venter, J.C.; Adams, M.D.; Myers, E.W.; Li, P.W.; Mural, R.J.; Sutton, G.G. Science, 2001, 291, 1304.
13. Orphanides, G.; Lagrange, T.; Reinberg, D. Gene Develop., 1996, 10, 2657.
14. Hurst, H.C. Eur. J. Cancer, 1996, 32A, 1857.
15. Patiglou, G.; Burley, S.K. Annu. Rev. Biophys, Biomol. Struct., 1997, 26, 289.
16. Bartkowiak, J.; Kapuscinski, J.; Melamed, M.R.; Darzynkiewicz, Z. Proc. Natl. Acad Sci. USA, 1989, 86, 5151.
17. Broggini, M.; Ponti, M.; Ottolenghi, S.; D'Incalci, M.; Mongelli, N.; Mantovani, R. Nucleic Acids Res., 1989, 17, 1051.
18. Gniazdowski, M.; Czyz, M. Acta Biochim. Pol., 1999, 46, 255.
19. Ray, R.; Snyder, R.C.; Thomas, S.; Koller, C.A.; Miller, D.M. J. Clin. Invest., 1989, 83, 2003.
20. Snyder, R.C.; Ray, R.; Blume, S.; Miller, D.M. Biochemistry, 1991, 30, 4290.
21. Welch, J.J.; Rauscher, III F.J.; Beerman, T.A. J. Biol. Chem., 1994, 269, 31051.
22. Broggini, M.; D'Incalci, M. Anti-Cancer Drug Design, 1994, 9, 373.
23. Sun, D.; Hurley, L.H. Gene, 1994, 149, 165.
24. Ho, S.N.; Boyer, S.H.; Schreiber, S.L.; Danishefsky, S.J.; Crabtree, G.R. Proc. Natl. Acad. Sci. USA, 1994, 91, 9203.
25. Bellorini, M.; Moncollin, V.; D'Incalci, M.; Mongelli, N.; Mantovani, R. Nucleic Acids Res., 1995, 23, 1657.
26. Sun, D.; Hurley, L.H. Chem. Biol., 1995, 2, 457.
27. MacLeod, M.C.; Powell, K.L.; Tran, N. Carcinogenesis, 1995, 16, 975.
28. Gray, P.J. Nucleic Acids Res., 1995, 23, 4378.
29. Chow, C. S.; Whitehead, J.P.; Lippard, S.J. Biochemistry, 1994, 33, 15124.
30. Buhrmester, H.; von Kries, J.P.; Stratling, W.H. Biochemistry, 1995, 34, 4108.
31. MacLeod, M.C.; Powell, K.L.; Kuzmin, V.A.; Kolbanovskiy, A.; Geacintov, N.E. Mol. Carcinogenesis, 1996, 16, 44,
32. Bianchi, N.; Passadore, M.; Rutigliano, C.; Feriotto, G.; Mischiati, C.; Gambari, R. Biochem. Pharmacol., 1996, 52, 1489.
33. Cutts, S.M.; Parsons, P.G.; Sturm, R.A.; Phillips, D.R. J. Biol. Chem., 1996, 271, 5422.
34. Turchi, J.J.; Li, M.; Henkels, K.M. Biochemistry, 1996, 35, 2992.
35. Vichi, P.; Coin, F.; Renaud, J-P.; Vermeulen, W.; Hoeijmakers, J.H.J.; Moras, D.; Egly, J.-M. EMBO J., 1997, 16, 7444.
36. Taylor, A.; Webster, K.A.; Gustafson, T.A.; Kedes, L. Mol. Cell Biochem., 1997, 169, 61.
37. Johnson, D.G.; Coleman, A.; Powell, K.L.; MacLeod, M.C. Mol. Carcinogenesis, 1997, 20, 216.
38. Bruice, T.C,; Sengupta, D.; Blaskó, A.; Chiang, S.-Y.; Beerman, T.A. Bioorgan. Med. Chem., 1997, 5, 685.
39. Chiang, S.-Y.; Bruice, T.C.; Azizkhan, J.C.; Gawron, L.; Beerman, T.A. Proc. Natl. Acad. Sci. USA, 1997, 94, 2811.
40. Patrick, S.M.; Henkels, K.M.; Turchi, J.J. Biochim. Biophys. Acta, 1997, 1354, 279.
41. Jung, Y.; Mikata, Y.; Lippard, S.J. J. Biol. Chem., 2001, 276, 43589.
42. Hoffmann, J-S.; Locker, D.; Villani, G.; Leng M. J. Mol. Biol., 1997, 270, 539.
43. Dunham, S.U.; Lippard, S.J. Biochemistry, 1997, 36, 11428.
44. Czyz, M.; Gniazdowski, M. Acta Biochim. Pol., 1998, 45, 67.
45. Chiang, S-Y.; Azizkhan, J.C.; Beerman, T.A. Biochemistry, 1998, 37, 3109.
46. Trimmer, E.E.; Zamble, D.B.; Lippard, S.J.; Essigmann, J.M. Biochemistry, 1998, 37, 352.
47. Bonfanti, M.; La Valle, E.; Faro, J.-M.F.S.; Faircloth, G.; Caretti, G.; Mantovani, R.; D'Incalci, M. Anti-Cancer Drug Design, 1999, 14, 179.
48. Lee, S.J.; Hurley, L.H. J. Am. Chem. Soc., 1999, 121, 8971.
49. Rzeszowska-Wolny, J.; Widlak, P. Acta Biochim. Pol., 1999, 46, 173.
50. Dickinson, L.E.; Trauger, JW.; Baird, E.E.; Dervan, P.B.; Graves, B.J.; Gottesfeld, J.M. J. Biol. Chem., 1999, 274, 12765.
51. He, Q.; Ohndorf,U.M.; Lippard, S.J. Biochemistry, 2000, 39, 14426.
52. Lanuszewska, J.; Widlak, P. Cancer Lett., 2000, 158, 17.
53. Stuhlimeier, K.M. Biochim. Biophys. Acta, 2000, 1524, 57.
54. White, C.M.; Heidenreich, O.; Nordheim, A.; Beerman, T.A. Biochemistry, 2000, 39, 12262.
55. Rechkoblit, O.; Krzeminsky, J.; Amin, S.; Jernström, B.; Louneva, N.; Geacintov, N.E. Biochemistry, 2001, 40, 5622.
56. Ijaz, T.; Tran, P.; Ruparelia, K.C.; Teesdale-Spittle, P.H.; Orr, S.; Patterson, L.H. Bioorg. Med. Chem. Lett., 2001, 11, 351.
57. Imamura, T.; Izumi, H.; Nagatani, G.; Ise, T.; Nomoto, M.; Iwamoto, Y.; Kohno, K. J. Biol. Chem., 2001, 276, 7534.
58. Wilmanska, D.; Czyz, M.; Studzian, K.; Piestrzeniewicz, M.K.; Gniazdowski, M. Z. Naturforsch., 2001, 56c, 881.
59. Chatterjee, S.; Zaman, K.; Ryu, H.; Conforto, A.; Ratan, R.R. Ann. Neurol., 2001, 49, 345.
60. Ohndorf, U.-M.; Whitehead, J.P.; Raju, N.L.; Lippard, S.J. Biochemistry, 1997, 36, 1480T
61. Portugal, J.; Martin, B.; Vaquero, A.; Ferrer, N.; Villamarin, S.; Priebe, W. Curr. Med. Chem., 2001, 8, 1.
62. Chiang, S.Y.; Welch, J.; Rauscher, F.J. 3rd; Beerman, T.A. Biochemistry, 1994, 33, 7033.
63. Chiang, S.Y.; Burli, R.W.; Benz, C.C.; Gawron, L.; Scott, G.K.; Dervan, P.B.; Beerman, T.A. J. Biol. Chem., 2000, 275, 24246.
64. White, C.M.; Satz, A.L.; Bruice, T.C.; Beerman, T.A. Proc. Natl. Acad. Sci. USA, 2001, 98, 10590.
65. White, C.M.; Satz, A.L.; Gawron, L.S.; Bruice, T.C.; Beerman, T.A. Biochim. Biophys. Acta, 2002, 1574, 100.
66. Dickinson, L.A.; Gulizia, R.J.; Trauger, JW.; Baird, E.E.; Mosier, D.E.; Gottesfeld, J.M.; Dervan, P.B. Proc. Natl. Acad. Sci. USA, 1998, 95, 12890.
67. Ehley, J.A.; Melander, C.; Herman, D.; Baird, E.E.; Ferguson, H.A.; Goodrich, J.A.; Dervan, P.B.; Gottesfeld, J.M. Mol. Cell Biol., 2002, 22, 1723.
68. Wurtz, N.R.; Pomerantz, J.L.; Baltimore, D., Dervan, P.B. Biochemistry, 2002, 41, 7604.
69. Chiang, S.-Y.; Welch, J.J.; Rauscher, F.J.; Beerman, T.A. J. Biol. Chem., 1996, 271, 23999.
70. Feriotto, G.; Mischiati, C.; Bianchi, N.; Passadore, M.; Gambari, R. Eur. J. Pharmacol., 1995, 290, 85.
71. Dickinson, L.A.; Trauger, J.W.; Baird, E.E.; Ghazal, P.; Dervan, P.B.; Gottesfeld, J.M. Biochemistry, 1999, 38, 10801.
72. Henderson, D.; Hurley, L.H. Nature Med., 1995, 1, 525.
73. Zewail-Foote, M.; Hurley, L.H. Anti-Cancer Drug Design, 1999, 14, 1.
74. Turner, P.R.; Denny, W.A. Curr. Drug Targets, 2000, 1, 1.
75. Satz, A.L.; White, C.M.; Beerman, T.A.; Bruice, T.C. Biochemistry, 2001, 40, 6465.
76. Gieseg, M.A.; de Bock, C.; Turner, P.M.; Ferguson, L.R.; Denny, W.A. Anticancer Drugs, 2002, 13, 271.
77. Brown, K. Methods, 2002, 26, 10.
78. Kuo, M.H.; Allis, C.D. Methods, 1999, 19, 425.
79. Wells, J.; Farnham, P. J. Methods, 2002, 26, 48.
80. Gambari, R.; Feriotto, G.; Rutigliano, C.; Bianchi, N.; Mischiati, C. J. Pharmacol. Exp. Ther., 2000, 294, 370.
81. Supekova, L.; Pezacki, J.P.; Su, A.I.; Loweth, C.J.; Riedl, R.; Geierstanger, B.; Schultz, P.G.; Wemmer, D.E. Chem. Biol, 2002, 9, 821.
82. Burgess, J.K. Clin. Exp. Pharmacol. Physiol., 2001, 28, 321.
83. Martinez, E.J.; Owa, T.; Schreiber, S.L.; Corey, E.J. Proc. Natl. Acad. Sci. USA, 1999, 96, 3496.
84. Wakelin, L.P.G. Med Res. Rev., 1986, 6, 275.
85. Assa-Munt, N.; Denny, W.A.; Leupin, W.; Kearns, D.R. Biochemistry, 1985, 24, 1441.
86. Guichard, S.M.; Danks, M.K. Curr. Opin. Oncol., 1999, 11, 482.
87. Denny, W.A.; Baguley, B.C. Curr. Top. Med. Chem., 2003, 3, 339.
88. Bailly, C. Curr. Med. Chem., 2000, 7, 39.
89. Chakrabarti, S.; Bhattacharyya, D.; Dasgupta, D. Biopolymers, 2001, 56, 85.
90. Kopka, M.L.; Goodsell, D.S.; Han, G.W.; Chiu, T.K.; Lown, J.W.; Dickerson, R.E. Structure, 1997, 5, 1033.
91. Sharma, S.K.; Reddy, B.S.N.; Lown, J.W. Drugs Future, 2001, 26, 39.
92. White, S.; Szewczyk, J.W.; Turner, J.M.: Baird, E.E.; Dervan, P.B. Nature, 1998, 391, 468.
93. Bremer, R.E.; Wurtz, N.R.; Szewczyk, J.W.; Dervan, P.B, Bioorg. Med. Chem., 2001, 9, 2093.
94. Bremer, R.E.; Baird, F.E.; Dervan, P.B. Chem. Biol., 1998, 5, 119.
95. Millard, J.T.; Raucher, S.; Hopkins, P.B. J. Amer. Chem. Soc., 1990, 112, 2459.
96. Broggini, M.; Coley, H.M.; Mongelli, N.; Pesenti, E.; Wyatt, M.D.; Hartley, J.A.; D'Incalci, M. Nucleic Acids Res., 1995, 23, 81.
97. Smaill, JB.; Fan, J-Y.; Papa, P.V.; O'Connor, C.J.; Denny, W.A. Anti-Cancer Drug Design, 1998, 13, 221.
98. Prakash, A.S.; Denny, W.A.; Gourdie, T.A.; Valu, K.K.; Woodgate, P.D.; Wakelin, L.P.G. Biochemistry, 1990, 29, 9799.
99. Perego, P.; Gatti, L.; Caserini, C.; Supino, R.; Colangelo, D.; Leone, R.; Spinelli, S.; Farrell, N.; Zunino, F. J. Inorg. Biochem., 1999, 77, 59.
100. Hurley, L.H.; Reck, T.; Thurston, DE.; Langley, D.R.; Holden, K.G.; Hertzberg, R.P.; Hoover, J.R.; Gallagher, G.; Faucette, L.F.; Mong, S.M. Chem. Res. Tox., 1988, 1, 258.
101. Boger, D.L.; Johnson, D.S. Angew. Chem. Int. Ed., 1996, 35, 1438.
102. Fan, J-Y.; Tercel, M.; Denny, W.A. Anti-Cancer Drug Design, 1997, 12, 277.
103. Hélene, C. In DNA-Ligand Interactions - From drugs to proteins; Guschlbauer, W.; Saenger, W, Eds.; Plenum Press: New York, London, 1987, pp. 127-140.
104. Putnam, D.A. Am. J. Health- Syst. Pharm., 1996, 53, 151.
105. Praseuth, D.; Guieysse, A.L.; Hélene, C. Biochim. Biophys. Acta, 1999, 1489, 181.
106. Nielsen, P.E. Curr. Opinion Struct. Biol., 1999, 9, 353.
107. Nielsen, P.E. Pharmacol. Toxicol., 2000, 86, 3.
108. Faria, M.; Giovannangeli, C. J. Gene Med., 2001, 3, 299.
109. Ray, A.; Nordén, B. FASEB J., 2000, 14, 1041.
110. Escude, C.; Nguyen, C.H.; Kukreti, S.; Janin, Y.; Sun, Y.-S.; Bisagni, E.; Garestier, T.; Hélène, C. Proc. Natl. Acad. Sci. USA, 1998, 95, 3591.
111. Guga, P.; Koziolkiewicz, M.; Okruszek, A.; Stec, W.J. In Applied Antisense Oligonucleotide Technology; Stein, C.A.; Krieg, A.M. Eds.; Wiley-Liss Inc.: 1998, pp. 25-30.
112. Agrawal, S.; Kandimalla, E.R. Mol. Med. Today, 2000, 6, 72.
113. Wittung, P.; Nielsen, P.; Norden, B. Biochemistry, 1997, 36, 7973.
114. Uhlmann, E. Chem. Biol., 1998, 379, 1045.
115. Guieysse, A.L.; Praseuth, D.; Giovannangeli, C.; Asseline, U.; Hélene, C. J. Mol. Biol., 2000, 296, 373.
116. Le Doan, T.; Perrouault, L.; Praseuth, D.; Habhoub, N.; Decout, J.-L.; Thuong, N.T.; Lhomme, J.; Hélene, C. Nucleic Acids Res., 1987, 15, 7749.
117. Giraud-Panis, M.-J.; Leng, M. Pharmacol. Therap., 2000, 85, 175.
118. Black, A.R.; Black, J.D.; Azizkhan-Clifford, J. J. Cell Physiol., 2001, 188, 143.
119. Sen, R.; Baltimore, D. Cell, 1986, 46, 705.
120. Mayo, M.W.; Baldwin, A.S. Biochim Biophys Acta, 2000, 1470, M55.
121. Karin, M.; Cao, Y.; Greten, F.R.; Li, Z.W. Nature Rev. Cancer, 2002, 2, 301.
122. Shaulian, E.; Karin, M. Nature Cell Biol., 2002, 4, E131.
123. Adamson, E.D.; Mercola, D. Tumour Biol., 2002, 23, 93.
124. Christy, B.; Nathans, D. Proc. Natl. Acad Sci USA, 1989, 86, 8737.
125. Treiber, D.K.; Zhai, X.; Jantzen, H-M.; Essigman, J.M. Proc. Natl. Acad Sci. USA, 1994, 91, 5672.
126. Wei, M.; Cohen, S.M.; Silverman, A.P.; Lippard, S.J. J. Biol. Chem., 2001, 276, 38774.
127. Wetzel, C.C.; Berberich, S.J. Biochim. Biophys. Acta, 2001, 1517, 392.
128. Cryer, J.E.; Johnson, S.W.; Engelsberg, B.N.; Billings, P.C. Cancer Chemother. Pharmacol., 1996, 38, 163.
129. Yarnell, A.T.; Oh, S.; Reinberg, D.; Lippard, S.J. J. Biol. Chem., 2001, 276, 25736.
130. Zlatanova, J.; Yaneva, J.; Leuba, S.H. FASEB J., 1998, 12, 791.
131. D'Incalci, M.; Erba, E.; Damia, G.; Galliera, E.; Carrassa, L.; Marchini, S.; Mantovani, R.; Tognon, G.; Fruscio, R.; Jimeno, J.; Faircloth, G.T. Oncologist, 2002, 7, 210.
132. Pommier, Y.; Kohlhagen, G.; Bailly, C.; Waring, M.; Mazumder, A.; Kohn, K.W. Biochemistry, 1996, 35, 13303.
133. Garcia-Nieto, R.; Manzanares, I; Cuevas, C.; Gago F. J. Amer. Chem. Soc., 2000, 122, 7172.
134. Zewail-Foote, M.: Hurley, L.H. J. Am. Chem. Soc., 2001, 123, 6485.
135. Jin, S.; Gorfajn, B.; Faircloth, G.; Scotto, K.W. Proc. Natl. Acad. Sci. USA, 2000, 97, 6775.
136. Minuzzo, M.; Marchini, S.; Broggini, M.; Faircloth, G.; D'Incalci, M.; Mantovani, R. Proc. Natl. Acad. Sci. USA, 2000, 97, 6780.
137. Friedman, D.; Hu, Z.; Kolb, E.A.; Gorfajn, B.; Scotto, K.W. Cancer Res., 2002, 62, 3377.
138. Martinez, E.J.; Corey, E.J.; Owa, T. Chem. Biol., 2001, 8, 1151.
139. Adams, J.; Elliott, P.J. Oncogene, 2000, 19, 6687.
140. Marco, E.; Garcia-Nieto, R.; Mendieta, J.; Manzanares, I.; Cuevas, C.; Gago, F. J. Med. Chem., 2002, 45, 871.
141. Damia, G.; Silvestri, S.; Carrassa, L.; Filiberti, L.; Faircloth, G.T.; Liberi, G.; Foiani, M.; D'Incalci, M. Int. J. Cancer, 2001, 92, 583.
142. Takebayashi, Y.; Pourquier, P.; Zimonjic, D.B.; Nakayama, K.; Emmert, S.; Ueda, T.; Urasaki, Y.; Kanzaki, A.; Akiyama, S.I.; Popescu, N.; Kraemer, K.H.; Pommier, Y. Nat. Med., 2001, 7, 961.
143. Wang, Y.D.; Dziegielewski, J.; Chang, A.Y.; Dervan, P.B.; Beerman, T.A. J. Biol. Chem., 2002, 277, 4231.
144. Belitsky, J.M.; Leslie, S.J.; Arora, P.S.; Beerman, T.A.; Dervan, P.B. Bioorg. Med. Chem., 2002, 10, 3313.
145. Nielsen, P.E.; Egholm, M.; Buchardt, O. Gene, 1994, 149, 139.
146. Grigoriev, M.; Praseuth, D.; Robin, P.; Hemar, A.; Saison-Behmoaras, T.; Dautry- Varsat, A.; Thuong, N.T.; Hélène, C.; Harel-Bellan, A. J. Biol. Chem., 1992, 267, 3389.
147. Vickers, T.A.; Griffith, M.C.; Ramasamy, K.; Risen, L.M.; Freier, S.M. Nucleic Acids Res., 1995, 23, 3003.
148. Janicek, M.F.; Sevin, B.U.; Nguyen, H.N.; Averette, H.E. Gynecol. Oncol., 1995, 59, 87.
149. Barre, F.-X.; Giovannangeli, C.; Hélene, C.; Harel-Bellan, A. Nucleic Acids Res., 1999, 27, 743.
150. Perkins, B.D.; Wensel, T.G.; Vasquez, K.M.; Wilson, J.H. Biochemistry, 1999, 38, 12850.
151. Faria, M.; Wood, C.D.; Perrouault, L.; Nelson, J.S.; Winter, A.; White, M.R.H.; Hélene, C.; Giovannangeli, C. Proc. Natl. Acad. Sci. USA, 2000, 97, 3862.
152. McGuffie, E.M.; Pacheco, D.; Carbone, G.M.; Catapano, C.V. Cancer Res., 2000, 60, 3790.
153. Bielihska, A.; Shivdasani, R.A.; Zhang, L.; Nabel, G.J. Science, 1990, 250, 997.
154. Wagner, A.H.; Krzesz, R.; Gao, D.; Schroeder, Ch.; Cattaruzza, M.; Hecker, M. Mol. Pharmacol., 2000, 58, 1333.
155. Cooper, J.A.D.; Parks, J.M.; Carcelen, R.; Kablon, S.S.; Sheffield, M.; Culbreth, R. Biochem. Pharmacol., 2000, 59, 605.
156. Piva, R.; del Senno, L.; Lambertini, E.; Penolazzi, L; Nastruzzi, C. J. Steroid. Biochem. Mol. Biol., 2000, 75, 121.
157. Lambertini, E.; Penolazzi, L; Aguaiari, G.; del Senno, L.; Pezzetti, F.; Solazzo, V.; Piva, R. Biochem. Biophys. Res. Commun., 2002, 292, 761.
158. Larsen, H.J.; Nielsen, P.E. Nucleic Acids Res., 1996, 24, 458.
159. Praseuth, D.; Grigoriev, M.; Guieysse, A.L.; Pritchard, L.L.; Harel-Bellan, A.; Nielsen, P.E.; Hélène, C. Biochim. Biophys. Acta, 1996, 1309, 226.
160. Park, Y.G.; Nesterova, M.; Agrawal, S.; Cho-Chung, Y.S. J. Biol. Chem., 1999, 274, 1573.
161. Yang, X.; Fennewald, S.; Luxon, B.A.; Aronson, J.; Herzog, N.K.; Gorenstein, D.G. Bioorg. Med. Chem. Lett., 1999, 9, 3357.
162. Mischiati, C.; Borgatti, M.; Bianchi, N.; Rutigliano, C.; Tomassetti, M.; Feriotto, G.; Gambari, R. J. Biol. Chem., 1999, 274, 33114.
163. Mollegaard, N.E.; Buchardt, O.; Egholm, M.; Nielsen, P.E. Proc. Natl. Acad. Sci. USA, 1994, 91, 3892.
164. Chen, A.Y.; Liu, L.F. Annu. Rev. Pharmacol. Toxicol., 1994, 34, 191.
165. Garcia-Nieto, R.; Manzanares, I.; Cuevas, C.; Gago, F. J. Med. Chem., 2000, 43, 4367.
166. Rink, S.M.; Yarema, K.J.; Solomon, M.S.; Paige, L.A.; Tadayoni-Rebek, B.M.; Essigmann, J.M.; Croy, R.G. Proc. Natl. Acad. Sci. USA, 1996, 93, 15063.
167. Beckerbauer, L.; Tepe, J.J.; Cullison, J.; Reeves, R.; Williams, R.M. Chem. Biol., 2000, 7, 805.
168. Samuel, S.K.; Spencer, V.A.; Bajno, L.; Sun, J.M.; Holth, L.T.; Oesterreich, S.; Davie, J,R. Cancer Res., 1998, 58, 3004.
169. Hélene, C. Nature, 1998, 391, 436.
170. Urbach, A.R.; Love, J.J.; Ross, S.A.; Dervan, P.B. J. Mol. Biol., 2002, 320, 55.
171. Klug, A. J. Mol. Biol., 1999, 293, 215.
172. Stanojevic, D.; Young, R.A. Biochemistry, 2002, 41, 7209.
173. Liu, B.; Han, Y.; Corey, DR.; Kodadek, T. J. Am. Chem. Soc., 2002, 124, 1838.
174. Karamouzis, M.V.; Gorgoulis, V.G.; Papavassiliou, A.G. Clin. Cancer Res., 2002, 8, 949.
175. Jones, A.; Harris, A.L. Cancer J., 1998, 4, 209.
176. Wingender, E.; Chen, X.; Fricke, E.; Geffers, R.; Hehl, R.; Liebich, I.; Krull, M.; Matys, V.; Michael, H.; Ohnhauser, R.; Pruss, M.; Schacherer, F.; Thiele, S.; Urbach, S. Nucleic Acids Res., 2001, 29, 281.