Synthesis and biological activity of DNA damaging agents that form decoy binding sites for the estrogen receptor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 26, 1996, Pages 15063-15068

  Rink, Stacia M ^a,b   Yarema, Kevin J ^a,c   Solomon, Marjorie S ^a   Paige, Lisa A ^a   Tadayoni Rebek, B Mitra ^a   Essigmann, John M ^a   Croy, Robert G ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

breast cancer; DNA repair; molecular recognition

Indexed keywords

ANILINE DERIVATIVE; CHLORMETHINE; ESTROGEN; ESTROGEN RECEPTOR; TRANSCRIPTION FACTOR;

ALKYLATION; ARTICLE; BINDING SITE; BREAST CANCER; CANCER CHEMOTHERAPY; CROSS LINKING; DNA ADDUCT; DNA BINDING; DNA DAMAGE; DNA REPAIR; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

ANILINE MUSTARD; ANTINEOPLASTIC AGENTS, ALKYLATING; BASE SEQUENCE; BINDING SITES; BREAST NEOPLASMS; CELL LINE; CELL SURVIVAL; DNA; DNA DAMAGE; DRUG DESIGN; FEMALE; HUMANS; MOLECULAR STRUCTURE; NITROGEN MUSTARD COMPOUNDS; OLIGODEOXYRIBONUCLEOTIDES; OVARIAN NEOPLASMS; RECEPTORS, ESTROGEN; TRANSCRIPTION FACTORS;

EID: 0030466324     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.26.15063     Document Type: Article

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