-
1
-
-
11944267365
-
Antisense oligonucleotides: A new therapeutic principle
-
Uhlmann E, Peyman A. Antisense oligonucleotides: a new therapeutic principle. Chem Rev. 1990; 90:543-4.
-
(1990)
Chem Rev.
, vol.90
, pp. 543-544
-
-
Uhlmann, E.1
Peyman, A.2
-
2
-
-
0021742961
-
Translationally associated helix-destabilizing activity in rabbit reticulocyte lysate
-
Liebhaber SA, Cash FE, Shakin SH. Translationally associated helix-destabilizing activity in rabbit reticulocyte lysate. J Biol Chem. 1984; 259:15597-602.
-
(1984)
J Biol Chem.
, vol.259
, pp. 15597-15602
-
-
Liebhaber, S.A.1
Cash, F.E.2
Shakin, S.H.3
-
3
-
-
0024041180
-
Role of RNase H in hybrid-arrested translation by antisense oligonucleotides
-
Walder RY, Walder JA Role of RNase H in hybrid-arrested translation by antisense oligonucleotides. Proc Natl Acad Sci U S A. 1988; 85:5011-5.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 5011-5015
-
-
Walder, R.Y.1
Walder, J.A.2
-
4
-
-
0025058003
-
Site-specific inhibition of EcoRI restriction/modification enzymes by a DNA triple helix
-
Hanvey JC, Shimizu M, Wells RD. Site-specific inhibition of EcoRI restriction/modification enzymes by a DNA triple helix. Nucleic Acids Res. 1990; 18:157-61.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 157-161
-
-
Hanvey, J.C.1
Shimizu, M.2
Wells, R.D.3
-
5
-
-
0026349087
-
The anti-gene strategy: Control of gene expression by triplex-forming oligonucleotides
-
Helene C. The anti-gene strategy: control of gene expression by triplex-forming oligonucleotides. Anticancer Drug Des. 1991; 6:569-74.
-
(1991)
Anticancer Drug Des.
, vol.6
, pp. 569-574
-
-
Helene, C.1
-
6
-
-
0026336817
-
Oligonucleotides as therapeutic agents
-
Cohen JS. Oligonucleotides as therapeutic agents. Pharmacol Ther. 1991; 52:221-5.
-
(1991)
Pharmacol Ther.
, vol.52
, pp. 221-225
-
-
Cohen, J.S.1
-
7
-
-
0023221419
-
A small catalytic oligoribonucleotide
-
Uhlenbeck OC. A small catalytic oligoribonucleotide. Nature. 1987; 328:596-610
-
(1987)
Nature
, vol.328
, pp. 596-610
-
-
Uhlenbeck, O.C.1
-
8
-
-
0026523627
-
Ribozymes as anti-HIV therapeutic agents: Principles, applications, and problems
-
Rossi JJ, Elkins D, Zaia JA et al. Ribozymes as anti-HIV therapeutic agents: principles, applications, and problems. AIDS Res Hum Retroviruses. 1992; 8:183-9.
-
(1992)
AIDS Res Hum Retroviruses
, vol.8
, pp. 183-189
-
-
Rossi, J.J.1
Elkins, D.2
Zaia, J.A.3
-
9
-
-
0025968051
-
Ribozymes that cleave an RNA sequence from human immunodeficiency virus: The effect of flanking sequence on rate
-
Goodchild J, Kohli V. Ribozymes that cleave an RNA sequence from human immunodeficiency virus: the effect of flanking sequence on rate. Arch Biochem Biophys. 1991; 284:386-91.
-
(1991)
Arch Biochem Biophys.
, vol.284
, pp. 386-391
-
-
Goodchild, J.1
Kohli, V.2
-
10
-
-
0025051353
-
Ribozymes correctly cleave a model substrate and endogenous RNA in vivo
-
Saxena SK, Ackerman EJ. Ribozymes correctly cleave a model substrate and endogenous RNA in vivo. J Biol Chem. 1990; 265:17106-9.
-
(1990)
J Biol Chem.
, vol.265
, pp. 17106-17109
-
-
Saxena, S.K.1
Ackerman, E.J.2
-
11
-
-
0026175538
-
Ribozyme-mediated cleavage of an HIV-1 gag RNA: The effects of non-targeted sequences and secondary structure on ribozyme cleavage activity
-
Taylor N, Rossi JJ. Ribozyme-mediated cleavage of an HIV-1 gag RNA: the effects of non-targeted sequences and secondary structure on ribozyme cleavage activity. Antisense Res Dev. 1991; 1:173-86.
-
(1991)
Antisense Res Dev.
, vol.1
, pp. 173-186
-
-
Taylor, N.1
Rossi, J.J.2
-
12
-
-
0001477721
-
Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA
-
Zamecnik PC, Goodchild Y, Taguchi Y et al. Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA. Proc Natl Acad Sci U S A. 1986; 83:4143-6.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 4143-4146
-
-
Zamecnik, P.C.1
Goodchild, Y.2
Taguchi, Y.3
-
13
-
-
0023755696
-
Oligodeoxynucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus
-
Agrawal S, Goodchild J, Civeira MP et al. Oligodeoxynucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus. Proc Natl Acad Sci U S A. 1988; 85:7079-83.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 7079-7083
-
-
Agrawal, S.1
Goodchild, J.2
Civeira, M.P.3
-
14
-
-
0001476029
-
Inhibition of acquired immunodeficiency syndrome virus by oligodeoxynucleoside methylphosphonates
-
Sarin PS, Agrawal S, Civeira MP et al. Inhibition of acquired immunodeficiency syndrome virus by oligodeoxynucleoside methylphosphonates. Proc Natl Acad Sci U S A. 1998; 85:7448-51.
-
(1998)
Proc Natl Acad Sci U S A
, vol.85
, pp. 7448-7451
-
-
Sarin, P.S.1
Agrawal, S.2
Civeira, M.P.3
-
15
-
-
0023447274
-
Phosphorothioate analogs of oligodeoxynucleotides: Inhibitors of replication and cytopathic effects of human immunodeficiency virus
-
Matsukura M, Shinozuka K, Zon G et al. Phosphorothioate analogs of oligodeoxynucleotides: inhibitors of replication and cytopathic effects of human immunodeficiency virus. Proc Natl Acad Sci U S A. 1987; 84:7706-10.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 7706-7710
-
-
Matsukura, M.1
Shinozuka, K.2
Zon, G.3
-
16
-
-
0025552906
-
Innovations in the use of antisense oligonucleotides
-
Zon G. Innovations in the use of antisense oligonucleotides. Ann N Y Acad Sci. 1990; 616:161-72.
-
(1990)
Ann N Y Acad Sci.
, vol.616
, pp. 161-172
-
-
Zon, G.1
-
17
-
-
0000600241
-
Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligodeoxynucleotide against rev(art/trs) in chronically infected cells
-
Matsukura M, Zon G, Shinozuka K et al. Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligodeoxynucleotide against rev(art/trs) in chronically infected cells. Proc Natl Acad Sci U S A. 1989; 86:4244-8.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 4244-4248
-
-
Matsukura, M.1
Zon, G.2
Shinozuka, K.3
-
18
-
-
0001717745
-
Ribozyme-mediated sitespecific cleavage of the HIV-1 genome
-
Chang P, Cantin EM, Zaia JA et al. Ribozyme-mediated sitespecific cleavage of the HIV-1 genome. Clin Biotechnol. 1990; 2:23-31.
-
(1990)
Clin Biotechnol.
, vol.2
, pp. 23-31
-
-
Chang, P.1
Cantin, E.M.2
Zaia, J.A.3
-
19
-
-
0025021952
-
Hairpin catalytic RNA model: Evidence for helices and sequence requirement for substrate RNA
-
Hampel A, Tritz R, Hicks M et al. Hairpin catalytic RNA model: evidence for helices and sequence requirement for substrate RNA. Nucleic Acids Res. 1990; 18:299-304.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 299-304
-
-
Hampel, A.1
Tritz, R.2
Hicks, M.3
-
20
-
-
0025347975
-
A randomized, controlled trial of Interferon alfa-2b alone and after prednisone withdrawal for the treatment of chronic hepatitis B
-
Perillo RP, Schiff ER, Davie GL et al. A randomized, controlled trial of Interferon alfa-2b alone and after prednisone withdrawal for the treatment of chronic hepatitis B. N Engl J Med. 1990; 323:295-301.
-
(1990)
N Engl J Med.
, vol.323
, pp. 295-301
-
-
Perillo, R.P.1
Schiff, E.R.2
Davie, G.L.3
-
22
-
-
0027528518
-
In vivo inhibition of duck hepatitis B virus replication and gene expression by phosphorothioate modified antisense oligodeoxynucleotides
-
Offensperger WB, Offensperger S, Walter E et al. In vivo inhibition of duck hepatitis B virus replication and gene expression by phosphorothioate modified antisense oligodeoxynucleotides. EMBO J. 1993; 12:1257-62.
-
(1993)
EMBO J.
, vol.12
, pp. 1257-1262
-
-
Offensperger, W.B.1
Offensperger, S.2
Walter, E.3
-
23
-
-
0026688793
-
Specific inhibition of hepatitis B viral gene expression in vitro by targeted antisense oligonucleotides
-
Wu GY, Wu CH. Specific inhibition of hepatitis B viral gene expression in vitro by targeted antisense oligonucleotides. J Biol Chem. 1992; 267:12436-9.
-
(1992)
J Biol Chem.
, vol.267
, pp. 12436-12439
-
-
Wu, G.Y.1
Wu, C.H.2
-
24
-
-
0007684104
-
Site specificity of the inhibitory effects of oligo(nucleoside methylphosphonate)s complementary to the acceptor splice junction of herpes simplex virus type 1 immediate early mRNA 4
-
Kulka M, Smith CC, Aurelian L et al. Site specificity of the inhibitory effects of oligo(nucleoside methylphosphonate)s complementary to the acceptor splice junction of herpes simplex virus type 1 immediate early mRNA 4. Proc Natl Acad Sci U S A. 1989; 86:6868-72.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 6868-6872
-
-
Kulka, M.1
Smith, C.C.2
Aurelian, L.3
-
25
-
-
0027103753
-
Epstein-Barr viral latency and cell immortalization as targets for antisense oligomers
-
Pagano JS, Jimenez G, Sung NS et al. Epstein-Barr viral latency and cell immortalization as targets for antisense oligomers. Ann N Y Acad Sci. 1992; 660:107-16.
-
(1992)
Ann N Y Acad Sci.
, vol.660
, pp. 107-116
-
-
Pagano, J.S.1
Jimenez, G.2
Sung, N.S.3
-
26
-
-
0027399409
-
In vitro evaluation of phosphorothioate oligonucleotides targeted to the E2 mRNA of papillomavirus: Potential treatment for genital warts
-
Cowsert LM, Fox MC, Zon G et al. In vitro evaluation of phosphorothioate oligonucleotides targeted to the E2 mRNA of papillomavirus: potential treatment for genital warts. Antimicrob Agents Chemother. 1993; 37:171-7.
-
(1993)
Antimicrob Agents Chemother.
, vol.37
, pp. 171-177
-
-
Cowsert, L.M.1
Fox, M.C.2
Zon, G.3
-
27
-
-
0027267552
-
Antisense technology: Biological utility and practical considerations
-
Neckers L, Whitesell L. Antisense technology: biological utility and practical considerations. Am J Physiol. 1993; 9:L1-12.
-
(1993)
Am J Physiol.
, vol.9
-
-
Neckers, L.1
Whitesell, L.2
-
28
-
-
0027314371
-
Antisense technology for cancer therapy: Does it make sense?
-
Carter G, Lemoine NR. Antisense technology for cancer therapy: does it make sense? Br J Cancer. 1993; 67:869-76.
-
(1993)
Br J Cancer
, vol.67
, pp. 869-876
-
-
Carter, G.1
Lemoine, N.R.2
-
29
-
-
0026041988
-
Inhibition of protooncogene expression by antisense oligodeoxynucleotides: Biological and therapeutic implications
-
Calabretta B. Inhibition of protooncogene expression by antisense oligodeoxynucleotides: biological and therapeutic implications. Cancer Res. 1991; 51:4505-10.
-
(1991)
Cancer Res.
, vol.51
, pp. 4505-4510
-
-
Calabretta, B.1
-
30
-
-
0025124267
-
A potential role for antisense oligonucleotide analogues in the development of oncogene targeted cancer chemotherapy
-
Tidd DM. A potential role for antisense oligonucleotide analogues in the development of oncogene targeted cancer chemotherapy. Anticancer Res. 1990; 10:1169-82.
-
(1990)
Anticancer Res.
, vol.10
, pp. 1169-1182
-
-
Tidd, D.M.1
-
31
-
-
0023954113
-
An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyocytic cells and induces differentiation
-
Holt JT, Redner RL, Nienhuis AW. An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyocytic cells and induces differentiation. Mol Cell Biol. 1988; 8:963-73.
-
(1988)
Mol Cell Biol.
, vol.8
, pp. 963-973
-
-
Holt, J.T.1
Redner, R.L.2
Nienhuis, A.W.3
-
32
-
-
0028935119
-
Alterations of c-myc expression by antisense oligodeoxynucleotides enhance the induction of apoptosis in HL-60 cells
-
Kimura S, Maekawa T, Hirakawa K et al. Alterations of c-myc expression by antisense oligodeoxynucleotides enhance the induction of apoptosis in HL-60 cells. Cancer Res. 1995; 55:1379-84.
-
(1995)
Cancer Res.
, vol.55
, pp. 1379-1384
-
-
Kimura, S.1
Maekawa, T.2
Hirakawa, K.3
-
33
-
-
0025312339
-
Tumour-specific inhibition of lymphoma growth by an antisense oligodeoxynucleotide
-
McManaway ME, Neckers LM, Loke SL et al. Tumour-specific inhibition of lymphoma growth by an antisense oligodeoxynucleotide. Lancet. 1990; 335:808-11.
-
(1990)
Lancet
, vol.335
, pp. 808-811
-
-
McManaway, M.E.1
Neckers, L.M.2
Loke, S.L.3
-
34
-
-
0025050969
-
Antisense inhibition of single copy N-myc expression results in decreased cell growth without reduction of c-myc protein in a neuroepithelioma cell line
-
Rosolen A, Whitesell L, Ikegaki N et al. Antisense inhibition of single copy N-myc expression results in decreased cell growth without reduction of c-myc protein in a neuroepithelioma cell line. Cancer Res. 1990; 50:6316-22.
-
(1990)
Cancer Res.
, vol.50
, pp. 6316-6322
-
-
Rosolen, A.1
Whitesell, L.2
Ikegaki, N.3
-
35
-
-
0026031868
-
Episome-generated N-myc antisense RNA restricts the differentiation potential of primitive neuroectodermal cell lines
-
Whitesell L, Rosolen A, Neckers LM. Episome-generated N-myc antisense RNA restricts the differentiation potential of primitive neuroectodermal cell lines. Mol Cell Biol. 1991; 11:1360-1.
-
(1991)
Mol Cell Biol.
, vol.11
, pp. 1360-1361
-
-
Whitesell, L.1
Rosolen, A.2
Neckers, L.M.3
-
36
-
-
0040668827
-
Anoligomer complementary to c-myb encoded mRNA inhibits proliferation of human myeloid leukemia cell lines
-
Anfossi G, Gerwirtz AM, Calabretta B. Anoligomer complementary to c-myb encoded mRNA inhibits proliferation of human myeloid leukemia cell lines. Proc Natl Acad Sci U S A. 1989; 86:3379-83.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 3379-3383
-
-
Anfossi, G.1
Gerwirtz, A.M.2
Calabretta, B.3
-
37
-
-
0026089494
-
Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: An in vitro study with relevance to bone marrow purging
-
Calabretta B, Sims RB, Valtieri M et al. Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study with relevance to bone marrow purging. Proc Natl Acad Sci U S A. 1991; 88:2351-5.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 2351-2355
-
-
Calabretta, B.1
Sims, R.B.2
Valtieri, M.3
-
38
-
-
0028580610
-
Treatment of chronic myelogenous leukemia (CML) with c-myb antisense oligodeoxynucleotides
-
Gewirtz AM. Treatment of chronic myelogenous leukemia (CML) with c-myb antisense oligodeoxynucleotides. Bone Marrow Transplant. 1994; 14(Suppl 3):S57-61.
-
(1994)
Bone Marrow Transplant
, vol.14
, Issue.3 SUPPL.
-
-
Gewirtz, A.M.1
-
39
-
-
0010535148
-
Autografting for chronic myelogenous leukemia (Cml) with c-myb antisense oligodeoxynucleotide purged bone marrow: A preliminary report
-
Abstract
-
Luger SM, Ratajczak MZ, Stadtmauer EA et al. Autografting for chronic myelogenous leukemia (Cml) with c-myb antisense oligodeoxynucleotide purged bone marrow: a preliminary report Blood. 1994; 84:(Suppl 1):151. Abstract.
-
(1994)
Blood
, vol.84
, Issue.1 SUPPL.
, pp. 151
-
-
Luger, S.M.1
Ratajczak, M.Z.2
Stadtmauer, E.A.3
-
40
-
-
0028243005
-
The basis of molecular strategies for treating coronary restenosis after angioplasty
-
Epstein ST, Speir E, Unger EF et al. The basis of molecular strategies for treating coronary restenosis after angioplasty. J Am Coll Cardiol. 1994; 23:1278-88.
-
(1994)
J Am Coll Cardiol.
, vol.23
, pp. 1278-1288
-
-
Epstein, S.T.1
Speir, E.2
Unger, E.F.3
-
41
-
-
0026612517
-
The restenosis paradigm revisted: An alternative proposal for cellular mechanisms
-
Schwartz RS, Holmes DR, Topol EJ. The restenosis paradigm revisted: an alternative proposal for cellular mechanisms. J Am Coll Cardiol. 1992; 20:1284-93.
-
(1992)
J Am Coll Cardiol.
, vol.20
, pp. 1284-1293
-
-
Schwartz, R.S.1
Holmes, D.R.2
Topol, E.J.3
-
42
-
-
0026773852
-
Inhibition of smooth muscle cell proliferation by an antisense oligodeoxynucleotide targeting the mRNA encoding PCNA
-
Speir E, Epstein SE. Inhibition of smooth muscle cell proliferation by an antisense oligodeoxynucleotide targeting the mRNA encoding PCNA. Circulation. 1992; 86:538-47.
-
(1992)
Circulation
, vol.86
, pp. 538-547
-
-
Speir, E.1
Epstein, S.E.2
-
43
-
-
0000392167
-
Inhibition of proliferation of human vascular smooth muscle cells using antisense oligonucleotides to PCNA
-
Abstract
-
Pickering G, Weir L, Jekanowski J et al. Inhibition of proliferation of human vascular smooth muscle cells using antisense oligonucleotides to PCNA. J Am Coll Cardiol. 1992; 19:165. Abstract.
-
(1992)
J Am Coll Cardiol.
, vol.19
, pp. 165
-
-
Pickering, G.1
Weir, L.2
Jekanowski, J.3
-
44
-
-
0027506930
-
Inhibitory effects of antisense oligodeoxynucleotides targeting c-myc mRNA on smooth muscle cell proliferation and migration
-
Biro S, Fu YM, Yu ZX et al. Inhibitory effects of antisense oligodeoxynucleotides targeting c-myc mRNA on smooth muscle cell proliferation and migration. Proc Natl Acad Sci U S A. 1993; 90:654-8.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 654-658
-
-
Biro, S.1
Fu, Y.M.2
Yu, Z.X.3
-
45
-
-
0027293123
-
Downregulation of c-myc expression by antisense oligonucleotides inhibits proliferation of human smooth muscle cells
-
Shi Y, Hutchinson HG, Hall DJ et al. Downregulation of c-myc expression by antisense oligonucleotides inhibits proliferation of human smooth muscle cells. Circulation. 1993; 88:1190-5.
-
(1993)
Circulation
, vol.88
, pp. 1190-1195
-
-
Shi, Y.1
Hutchinson, H.G.2
Hall, D.J.3
-
46
-
-
0026536410
-
Antisense nonmuscle myosin heavy chain and c-myb oligonucleotides suppress smooth muscle cell proliferation in vitro
-
Simons M, Rosenberg RD. Antisense nonmuscle myosin heavy chain and c-myb oligonucleotides suppress smooth muscle cell proliferation in vitro. Circ Res. 1992; 70:835-43.
-
(1992)
Circ Res.
, vol.70
, pp. 835-843
-
-
Simons, M.1
Rosenberg, R.D.2
-
47
-
-
0028219485
-
Inhibition of vascular smooth muscle cell proliferation in vitro and in vivo by c-myc antisense oligodeoxynucleotides
-
Bennett MR, Anglin S, McEwan JR et al. Inhibition of vascular smooth muscle cell proliferation in vitro and in vivo by c-myc antisense oligodeoxynucleotides. J Clin Invest. 1994; 93:820-8.
-
(1994)
J Clin Invest.
, vol.93
, pp. 820-828
-
-
Bennett, M.R.1
Anglin, S.2
McEwan, J.R.3
-
48
-
-
0028215639
-
Intimal hyperplasia after vascular injury is inhibited by antisense cdk 2 kinase oligonucleotides
-
Morishita R, Gibbons GH, Ellison KE et al. Intimal hyperplasia after vascular injury is inhibited by antisense cdk 2 kinase oligonucleotides. J Clin Invest. 1994; 93:1458-64.
-
(1994)
J Clin Invest.
, vol.93
, pp. 1458-1464
-
-
Morishita, R.1
Gibbons, G.H.2
Ellison, K.E.3
-
49
-
-
0025695743
-
Interleukin-1-induced interleukin-6 is required for the inhibition of proteoglycan synthesis by interleukin-1 in human articular cartilage
-
Nietfeld JJ, Wilbrink B, Helle M et al. Interleukin-1-induced interleukin-6 is required for the inhibition of proteoglycan synthesis by interleukin-1 in human articular cartilage. Arthritis Rheum. 1990; 33:1695-701.
-
(1990)
Arthritis Rheum.
, vol.33
, pp. 1695-1701
-
-
Nietfeld, J.J.1
Wilbrink, B.2
Helle, M.3
-
50
-
-
0028020955
-
Antisense oligonucleotides, a novel tool for the control of cytokine effects on human cartilage
-
Nietfeld JJ, Duits AJ, Tilanus MGJ et al. Antisense oligonucleotides, a novel tool for the control of cytokine effects on human cartilage. Arthritis Rheum. 1994; 37:1357-62.
-
(1994)
Arthritis Rheum.
, vol.37
, pp. 1357-1362
-
-
Nietfeld, J.J.1
Duits, A.J.2
Tilanus, M.G.J.3
-
51
-
-
0026458274
-
Specific inhibition of IgE antibody production by an antisense oligodeoxynucleotide oligomer
-
Hall TJ, Brostoff J. Specific inhibition of IgE antibody production by an antisense oligodeoxynucleotide oligomer. Immunology. 1992; 77:462-4.
-
(1992)
Immunology
, vol.77
, pp. 462-464
-
-
Hall, T.J.1
Brostoff, J.2
-
52
-
-
0022780091
-
Oligodeoxynucleotide stability in subcellular extracts and culture media
-
Wickstrom E. Oligodeoxynucleotide stability in subcellular extracts and culture media. J Biochem Biophys Methods. 1986; 13:97-102.
-
(1986)
J Biochem Biophys Methods
, vol.13
, pp. 97-102
-
-
Wickstrom, E.1
-
53
-
-
0026002671
-
Stability of modified antisense oligodeoxynucleotides in cellular extracts and sera
-
Akhtar S, Kole R, Juliano RL. Stability of modified antisense oligodeoxynucleotides in cellular extracts and sera. Life Sci. 1991; 49:1793-801.
-
(1991)
Life Sci.
, vol.49
, pp. 1793-1801
-
-
Akhtar, S.1
Kole, R.2
Juliano, R.L.3
-
54
-
-
0026357940
-
Phosphorothioate oligodeoxynucleotides: Antisense inhibitors of gene expression?
-
Stein CA, Tonkinson JL, Yakobov L. Phosphorothioate oligodeoxynucleotides: antisense inhibitors of gene expression? Pharmacol Ther. 1991; 52:365-74.
-
(1991)
Pharmacol Ther.
, vol.52
, pp. 365-374
-
-
Stein, C.A.1
Tonkinson, J.L.2
Yakobov, L.3
-
55
-
-
0028469243
-
Routine preparation of thiol oligonucleotides: Application to the synthesis of oligonucleotide-peptide hybrids
-
Ede NJ, Tregear GW, Haralambidis J. Routine preparation of thiol oligonucleotides: application to the synthesis of oligonucleotide-peptide hybrids. Bioconjug Chem. 1994; 5:373-8.
-
(1994)
Bioconjug Chem.
, vol.5
, pp. 373-378
-
-
Ede, N.J.1
Tregear, G.W.2
Haralambidis, J.3
-
56
-
-
0026920673
-
Cellular uptake and subcellular distribution of phosphorothioate oligonucleotides into cultured cells
-
Iversen PL, Shu S, Meyer A et al. Cellular uptake and subcellular distribution of phosphorothioate oligonucleotides into cultured cells. Antisense Res Dev. 1992; 2:211-2.
-
(1992)
Antisense Res Dev.
, vol.2
, pp. 211-212
-
-
Iversen, P.L.1
Shu, S.2
Meyer, A.3
-
57
-
-
0025552907
-
Large-scale economic synthesis of antisense phosphorothioate analogues of DNA for preclinical investigations
-
Geiser T. Large-scale economic synthesis of antisense phosphorothioate analogues of DNA for preclinical investigations. Ann N Y Acad Sci. 1990; 616:173-83.
-
(1990)
Ann N Y Acad Sci.
, vol.616
, pp. 173-183
-
-
Geiser, T.1
-
58
-
-
0025878768
-
The potential use of catalytic RNAs in therapy of HIV infection and other diseases
-
Rossi JJ, Cantin EM, Sarver N et al. The potential use of catalytic RNAs in therapy of HIV infection and other diseases. Pharmacol Ther. 1991; 50:245-54.
-
(1991)
Pharmacol Ther.
, vol.50
, pp. 245-254
-
-
Rossi, J.J.1
Cantin, E.M.2
Sarver, N.3
-
59
-
-
0028422387
-
Chemists create new oligonucleotide analogs for 'antisense' applications
-
Apr 18: News
-
Baum R. Chemists create new oligonucleotide analogs for 'antisense' applications. Chem Eng News. 1994; Apr 18:21-2. News.
-
(1994)
Chem Eng News
, pp. 21-22
-
-
Baum, R.1
-
60
-
-
0027246678
-
Antisense gene inhibition by oligonucleotides containing C-5 propyne pyrimidines
-
Wagner RW, Matteucci MD, Lewis JG et al. Antisense gene inhibition by oligonucleotides containing C-5 propyne pyrimidines. Science. 1993; 260:1510-3.
-
(1993)
Science
, vol.260
, pp. 1510-1513
-
-
Wagner, R.W.1
Matteucci, M.D.2
Lewis, J.G.3
-
61
-
-
0345570537
-
Characterization of oligonucleotide transport into living cells
-
Loke SL, Stein CA, Zhang XH et al. Characterization of oligonucleotide transport into living cells. Proc Natl Acad Sci U S A. 1989; 86:3474-8.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 3474-3478
-
-
Loke, S.L.1
Stein, C.A.2
Zhang, X.H.3
-
63
-
-
0025341615
-
Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes
-
Klibanov AL, Maruyama K, Torchilin VP et al. Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes. FEBS Lett. 1990; 268:235-7.
-
(1990)
FEBS Lett.
, vol.268
, pp. 235-237
-
-
Klibanov, A.L.1
Maruyama, K.2
Torchilin, V.P.3
-
64
-
-
0025731906
-
Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo
-
Allen TM, Hansen C, Martin F et al. Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo. Biochim Biophys Acta. 1991; 1066:29-36.
-
(1991)
Biochim Biophys Acta
, vol.1066
, pp. 29-36
-
-
Allen, T.M.1
Hansen, C.2
Martin, F.3
-
66
-
-
0028236818
-
Liposomal delivery of methylphosphonate antisense oligodeoxynucleotides in chronic myelogenous leukemia
-
Tari AM, Tucker SD, Deisseroth A et al. Liposomal delivery of methylphosphonate antisense oligodeoxynucleotides in chronic myelogenous leukemia. Blood. 1994; 84:601-7.
-
(1994)
Blood
, vol.84
, pp. 601-607
-
-
Tari, A.M.1
Tucker, S.D.2
Deisseroth, A.3
-
67
-
-
0028026739
-
Lipofectin-aided cell delivery of ribozyme targeted to human urokinase receptor mRNA
-
Kariko K, Megyen K, Xiao Qi et al. Lipofectin-aided cell delivery of ribozyme targeted to human urokinase receptor mRNA. FEBS Lett. 1994; 352:41-4.
-
(1994)
FEBS Lett.
, vol.352
, pp. 41-44
-
-
Kariko, K.1
Megyen, K.2
Qi, X.3
-
68
-
-
0027417416
-
Delivery of antisense oligonucleotides by poly(L-lysine) conjugation and liposome encapsulation
-
Clarenc JP, Degols G, Leonetti JP et al. Delivery of antisense oligonucleotides by poly(L-lysine) conjugation and liposome encapsulation. Anticancer Drug Des. 1993; 8:81-4.
-
(1993)
Anticancer Drug Des.
, vol.8
, pp. 81-84
-
-
Clarenc, J.P.1
Degols, G.2
Leonetti, J.P.3
-
69
-
-
0000738920
-
Conjugation of methotrexate to poly(L-lysine) increases drug transport and overcomes drug resistance in cultured cells
-
Ryser HJP, Shen W-C. Conjugation of methotrexate to poly(L-lysine) increases drug transport and overcomes drug resistance in cultured cells. Proc Natl Acad Sci U S A. 1978; 75:3867-70.
-
(1978)
Proc Natl Acad Sci U S A
, vol.75
, pp. 3867-3870
-
-
Ryser, H.J.P.1
Shen, W.-C.2
-
70
-
-
0025398291
-
Biological activity of oligonucleotide-poly(L-lysine) conjugates: Mechanism of cell uptake
-
Leonetti JP, Degols G, Lebleu B. Biological activity of oligonucleotide-poly(L-lysine) conjugates: mechanism of cell uptake. Bioconjug Chem. 1990; 1:149-53.
-
(1990)
Bioconjug Chem.
, vol.1
, pp. 149-153
-
-
Leonetti, J.P.1
Degols, G.2
Lebleu, B.3
-
71
-
-
0346551010
-
Polymer conjugates with anticancer activity
-
Putnam D, Kopecek J. Polymer conjugates with anticancer activity. Adv Polym Sci. 1995; 122:55-123.
-
(1995)
Adv Polym Sci.
, vol.122
, pp. 55-123
-
-
Putnam, D.1
Kopecek, J.2
-
72
-
-
0025099302
-
The potential of water-soluble polymeric carriers in targeted and site-specific drug delivery
-
Kopecek J. The potential of water-soluble polymeric carriers in targeted and site-specific drug delivery. J Controlled Release. 1990; 11:279-90.
-
(1990)
J Controlled Release
, vol.11
, pp. 279-290
-
-
Kopecek, J.1
-
73
-
-
0028037219
-
Antisense oligonucleotides adsorbed to polyalkylcyanoacrylate nanoparticles specifically inhibit mutated Ha-ras-mediated cell proliferation and tumorigenicity in nude mice
-
Schwab G, Chavany C, Duroux I et al. Antisense oligonucleotides adsorbed to polyalkylcyanoacrylate nanoparticles specifically inhibit mutated Ha-ras-mediated cell proliferation and tumorigenicity in nude mice. Proc Natl Acad Sci U S A. 1994; 91:10460-4.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 10460-10464
-
-
Schwab, G.1
Chavany, C.2
Duroux, I.3
-
75
-
-
0025175236
-
Disposition and metabolism of oligodeoxynucleoside methylphosphonate following a single iv injection in mice
-
Chem TL, Miller P, Ts'O P et al. Disposition and metabolism of oligodeoxynucleoside methylphosphonate following a single iv injection in mice. Drug Metab Dispos Biol Fate Chem. 1990; 18:815-8.
-
(1990)
Drug Metab Dispos Biol Fate Chem.
, vol.18
, pp. 815-818
-
-
Chem, T.L.1
Miller, P.2
Ts'O, P.3
-
76
-
-
0027729703
-
Systemic adminstration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: Initial results of a Phase I trial
-
Bayever E, Iversen PL, Bishop MR et al. Systemic adminstration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: initial results of a Phase I trial. Antisense Res Dev. 1993; 3:383-90.
-
(1993)
Antisense Res Dev.
, vol.3
, pp. 383-390
-
-
Bayever, E.1
Iversen, P.L.2
Bishop, M.R.3
|