Psoralen adducts induced by triplex-forming oligonucleotides are refractory to repair in HeLa cells

Journal of Molecular Biology

Volumn 296, Issue 2, 2000, Pages 373-383

  Guieysse, Anne Laure ^a   Praseuth, Danièle ^a   Giovannangeli, Carine ^a   Asseline, Ulysse ^b   Hélène, Claude ^a  

^a MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^b CENTRE DE BIOPHYSIQUE MOLÉCULAIRE   (France)

Author keywords

Oligonucleotide; Psoralen; Repair; Triple helix

Indexed keywords

DNA; ENDONUCLEASE; OLIGONUCLEOTIDE; PSORALEN;

ARTICLE; CROSS LINKING; DNA DAMAGE; DNA REPAIR; GENE EXPRESSION REGULATION; HELA CELL; HUMAN; HUMAN CELL; IRRADIATION; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION TERMINATION; TRIPLE HELIX;

EID: 0034681285     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.3466     Document Type: Article

References (41)

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2. Covalent crosslinks introduced via a triple helix-forming oligonucleotide coupled to psoralen are inefficiently repaired
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4. Reversible inhibition of gene expression by a psoralen functionalized triple helix forming oligonucleotide in intact cells
5. Specific inhibition of transcription by triple helix forming oligonucleotides
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7. Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells
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13. Detection of covalent triplex within human cells
14. Identification of a triplex-DNA binding protein from human cells
15. A damage-recognition protein which binds to DNA containing interstrand cross-links is absent or defective in Fanconi anemia, complementation group A, cells
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24. Selective removal of transcription-blocking DNA damage from the transcribed strand of the mamalian DHFR gene
25. Sequence specific cleavage of double helical DNA by triple helix formation
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27. Characterization of a purine-motif triplex DNA-binding proteins in HeLa extracts
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36. Inhibition of gene expression by triple helix formation in hepatoma cells
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