Genomic effects of polyamide/DNA Interactions on mRNA expression

Chemistry and Biology

Volumn 9, Issue 7, 2002, Pages 821-827

  Supekova, Lubica ^a   Pezacki, John Paul ^a,b   Su, Andrew I ^a,c   Loweth, Colin J ^a   Riedl, Rainer ^a   Geierstanger, Bernhard ^c   Schultz, Peter G ^a,c   Wemmer, David E ^d  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^c Genomic Institute of the Novetis Foundation   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; CALRETICULIN; COLONIC NEOPLASMS; DATABASES, GENETIC; DNA; DNA-BINDING PROTEINS; DOWN-REGULATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENES, BCL-1; HUMAN; MICROSCOPY, FLUORESCENCE; NUCLEIC ACID CONFORMATION; NYLONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; HUMANS; LYMPHOID ENHANCER-BINDING FACTOR 1;

CALRETICULIN; DNA; DNA BINDING PROTEIN; LEF1 PROTEIN, HUMAN; LYMPHOID ENHANCER FACTOR 1; MESSENGER RNA; NYLON; TRANSCRIPTION FACTOR;

ARTICLE; BINDING SITE; BIOSYNTHESIS; CELL CULTURE; CHEMISTRY; COLON TUMOR; CONFORMATION; DNA MICROARRAY; DOWN REGULATION; DRUG ANTAGONISM; FLUORESCENCE MICROSCOPY; GEL MOBILITY SHIFT ASSAY; GENETIC DATABASE; GENETIC TRANSCRIPTION; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; PROMOTER REGION; PROTO ONCOGENE;

EID: 0035989998     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(02)00174-6     Document Type: Article

References (29)

1. Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA
2. A nucleic-acid triple-helix formed by a peptide nucleic-acid DNA complex
3. PNA oligomers as tools for specific modulation of gene expression
4. An extensive class of small RNAs in Caenorhabditis elegans
5. RNA interference
6. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
7. Molecular recognition of DNA by small molecules
8. More than one way to skin a catenin
9. Sequence-specific double-strand cleavage of DNA by penta-N-methylpyrrolecarboxamide-EDTA•Fe(II)
10. Regulation of gene expression by small molecules
11. Targeting the Ets binding site of the HER2/neu promoter with pyrrole-imidazole polyamides
12. Sequence specific alkylation of DNA by hairpin pyrrole-imidazole polyamide conjugates
13. The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
14. Structural basis for DNA bending by the architectural transcription factor LEF-1
15. A library approach to the discovery of small molecules that recognize RNA: Use of a 1,3-hydroxyamine motif as core
16. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
17. Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis
18. 14-3-3 Proteins; Bringing new definitions to scaffolding
19. Application of cDNA microarrays to examine gene expression differences in schizophrenia
20. Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein
21. Computational identification of cis-regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae
22. Isolation, characterization and chromosomal localization of the human GADD153 gene
23. The 5′-flanking region of the human calreticulin gene shares homology with the human GRP78, GRP94, and protein disulfide isomerase promoters
24. Solid phase synthesis of polyamides containing imidazole and pyrrole amino acids
25. Identification of differentially expressed genes in human prostate cancer using subtraction and microarray
26. Molecular classification of human carcinomas by use of gene expression signatures
27. Genome-wide expression monitoring in Saccharomyces cerevisiae
28. Expression monitoring by hybridization to high-density oligonucleotide arrays
29. A lipophilic vasoactive intestinal peptide analog enhances the antiproliferative effect of chemotherapeutic agents on cancer cell lines