Promoter scanning for transcription inhibition with DNA-binding polyamides

Molecular and Cellular Biology

Volumn 22, Issue 6, 2002, Pages 1723-1733

  Ehley, Jennifer A ^a   Melander, Christian ^a   Herman, David ^a   Baird, Eldon E ^a   Ferguson, Heather A ^a   Goodrich, James A ^a   Dervan, Peter B ^a   Gottesfeld, Joel M ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; POLYAMIDE; RNA POLYMERASE; TATA BINDING PROTEIN;

ARTICLE; BINDING SITE; DNA BINDING; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; TRANSCRIPTION REGULATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0036183456     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.22.6.1723-1733.2002     Document Type: Article

References (45)

1. Solid phase synthesis of polyamides containing imidazole and pyrrole amino acids
2. Assembly of the isomerized TFIIA - TFIID - TATA ternary complex is necessary and sufficient for gene activation
3. DNA bending and wrapping around RNA polymerase: A "revolutionary" model describing transcriptional mechanisms
4. Topological localization of the human transcription factors IIA, IIB, TATA box-binding protein, and RNA polymerase II-associated protein 30 on a class II promoter
5. Bidirectional binding of the TATA box binding protein to the TATA box
6. Sequence-specific DNA recognition by polyamides
7. Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands
8. Inhibition of Ets-1 DNA binding and ternary complex formation between Ets-1, NF-kB, and DNA by a designed DNA-binding ligand
9. Anti-repression of RNA polymerase II transcription by pyrrole-imidazole polyamides
10. Eucaryotic gene transcription with purified components
11. Acetyl coenzyme A stimulates RNA polymerase II transcription and promoter binding by transcription factor IID in the absence of histones
12. Crystal structure of the yeast TFIIA/TBP/DNA complex
13. Chemical approaches to control gene expression
14. Affinity, stability and polarity of binding of the TATA binding protein governed by flexure at the TATA box
15. Role of SP1-binding domains in in vivo transcriptional regulation of the human immunodeficiency virus type 1 long terminal repeat
16. TBP, a universal eukaryotic transcription factor?
17. Specific gain-and loss-of-function phenotypes induced by satellite-specific DNA-binding drugs fed to Drosophila melanogaster
18. Chromatin opening of DNA satellites by targeted sequence-specific drugs
19. Structural arrangements of transcription control domains within the 5′-untranslated leader regions of the HIV-1 and HIV-2 promoters
20. Control of RNA initiation and elongation at the HIV-1 promoter
21. How proteins recognize the TATA box
22. Second-site long terminal repeat (LTR) revertants of replication-defective human immunodeficiency virus: Effects of revertant TATA box motifs on virus infectivity, LTR-directed expression, in vitro RNA synthesis, and binding of basal transcription factors TFIID and TFIIA
23. Structural basis for GC recognition in the DNA minor groove
24. Co-crystal structure of TBP recognizing the minor groove of a TATA element
25. Crystal structure of a yeast TBP/TATA-box complex
26. New core promoter element in RNA polymerase II-dependent transcription: Sequence-specific DNA binding by transcription factor IIB
27. High-resolution mapping of nucleoprotein complexes by site-specific protein-DNA photocrosslinking: Organization of the human TBP-TFIIA-TFIIB-DNA quaternary complex
28. Orchestrated response: A symphony of transcription factors for gene control
29. The Tax protein-DNA interaction is essential for HTLV-I transactivation in vitro
30. Repression of TFIIH transcriptional activity and TFIIH-associated cdk7 kinase activity at mitosis
31. Activation of gene expression by small molecule transcription factors
32. Minor groove DNA-protein contacts upstream of a tRNA gene detected with a synthetic DNA binding ligand
33. The general transcription factors of RNA polymerase II
34. Localization of subunits of transcription factors IIE and IIF immediately upstream of the transcriptional initiation site of the adenovirus major late promoter
35. Activation of the HIV-1 enhancer by the LEF-1 HMG protein on nucleosome-assembled DNA in vitro
36. TBP binding to the TATA box induces a specific downstream unwinding site that is targeted by pluramycin
37. Reconstitution of human TFIIA activity from recombinant polypeptides: A role in TFIID-mediated transcription
38. Crystal structure of a yeast TFIIA/TBP/DNA complex
39. Eukaryotic transcription factors
40. Subnanomolar sequence-specific recognition in the minor groove of DNA by designed ligands
41. Structural basis of preinitiation complex assembly on human po1 II promoters
42. Aliphatic/aromatic amino acid pairings for polyamide recognition in the minor groove of DNA
43. On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides
44. Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands
45. HIV-1 core promoter lacks a simple initiator element but contains a bipartite activator at the transcription start site