-
1
-
-
0032900953
-
Biochemical, cellular and pharmacological aspects of the multidrug transporter
-
Ambudkar, S. V., Dey, S., Hrycyna, M. R., Pastan, I., Gottesman, M. M. (1999) Biochemical, cellular and pharmacological aspects of the multidrug transporter. Annu. Rev. Pharmacol. Toxicol. 39: 361-398
-
(1999)
Annu. Rev. Pharmacol. Toxicol
, vol.39
, pp. 361-398
-
-
Ambudkar, S.V.1
Dey, S.2
Hrycyna, M.R.3
Pastan, I.4
Gottesman, M.M.5
-
2
-
-
0030839243
-
Drug interactions with grapefruit juice
-
Ameer, B., Weintraub, R. A. (1997) Drug interactions with grapefruit juice. Clin. Pharmacokinet. 33: 103-121
-
(1997)
Clin. Pharmacokinet.
, vol.33
, pp. 103-121
-
-
Ameer, B.1
Weintraub, R.A.2
-
3
-
-
0034751938
-
Effect of grapefruit juice on digoxin pharmacokinetics in humans
-
Becquemont, L., Verstuyft, C., Kerb, R., Brinkmann, U., Lebot, M., Jaillon, P., Funck-Brentano, C. (2001) Effect of grapefruit juice on digoxin pharmacokinetics in humans. Clin. Pharmacol. Ther. 70: 311-316
-
(2001)
Clin. Pharmacol. Ther.
, vol.70
, pp. 311-316
-
-
Becquemont, L.1
Verstuyft, C.2
Kerb, R.3
Brinkmann, U.4
Lebot, M.5
Jaillon, P.6
Funck-Brentano, C.7
-
4
-
-
0029793678
-
Influence of peppermint oil on absorptive and secretory processes in rat small intestine
-
Beesley, A., Hardcastle, J., Hardcastle, P. T., Taylor, C. J. (1996) Influence of peppermint oil on absorptive and secretory processes in rat small intestine. Gut 39: 214-219
-
(1996)
Gut
, vol.39
, pp. 214-219
-
-
Beesley, A.1
Hardcastle, J.2
Hardcastle, P.T.3
Taylor, C.J.4
-
5
-
-
0036070626
-
Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4
-
Bhardwaj, R. K., Glaeser, H., Becquemont, L., Klotz, U., Gupta, S. K., Fromm, M. F. (2002) Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4. J. Pharmacol. Exp. Ther. 302: 645-650
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.302
, pp. 645-650
-
-
Bhardwaj, R.K.1
Glaeser, H.2
Becquemont, L.3
Klotz, U.4
Gupta, S.K.5
Fromm, M.F.6
-
6
-
-
0033577042
-
Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer
-
Bracke, M. E., Depypere, H. T., Boterberg, T., Van Marck, V. L., Vennekens, K. M., Vanluchene, E., Nuytinck, M., Serreyn, R., Mareel, M. M. (1999) Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer. J. Natl Cancer Inst. 91: 354-359
-
(1999)
J. Natl Cancer Inst.
, vol.91
, pp. 354-359
-
-
Bracke, M.E.1
Depypere, H.T.2
Boterberg, T.3
Van Marck, V.L.4
Vennekens, K.M.5
Vanluchene, E.6
Nuytinck, M.7
Serreyn, R.8
Mareel, M.M.9
-
7
-
-
0034720558
-
Profound drop of ciclosporin A whole blood trough levels caused by St. John's wort (Hypericum perforatum)
-
Breidenbach, T., Kliem, V., Burg, M., Radermacher, J., Hoffmann, M. W., Klempnauer, J. (2000) Profound drop of ciclosporin A whole blood trough levels caused by St. John's wort (Hypericum perforatum). Transplantation 69: 2229-2230
-
(2000)
Transplantation
, vol.69
, pp. 2229-2230
-
-
Breidenbach, T.1
Kliem, V.2
Burg, M.3
Radermacher, J.4
Hoffmann, M.W.5
Klempnauer, J.6
-
8
-
-
0031060647
-
Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein
-
Castro, A. F., Altenberg, G. A. (1997) Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein. Biochem. Pharmacol. 53: 89-93
-
(1997)
Biochem. Pharmacol.
, vol.53
, pp. 89-93
-
-
Castro, A.F.1
Altenberg, G.A.2
-
9
-
-
0028172728
-
Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of P-gp as a putative mechanism
-
Critchfield, J. W., Welsh, C. J., Phang, J. M., Yeh, G. C. (1994) Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of P-gp as a putative mechanism. Biochem. Pharmacol. 48: 1437-1445
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 1437-1445
-
-
Critchfield, J.W.1
Welsh, C.J.2
Phang, J.M.3
Yeh, G.C.4
-
10
-
-
0036732050
-
Inhibitory effect of fruit extracts on P-glycoprotein-related efflux carriers: An in vitro screening
-
Deferme, S., Van Gelder, J., Augustijns, P. (2002a) Inhibitory effect of fruit extracts on P-glycoprotein-related efflux carriers: An in vitro screening. J. Pharm. Pharmacol. 54: 1213-1219
-
(2002)
J. Pharm. Pharmacol.
, vol.54
, pp. 1213-1219
-
-
Deferme, S.1
Van Gelder, J.2
Augustijns, P.3
-
11
-
-
0036892450
-
Apricot extract inhibits the P-gp mediated efflux of talinolol
-
Deferme, S., Mols, R., Van Driessche, W., Augustijns, P. (2002b) Apricot extract inhibits the P-gp mediated efflux of talinolol. J. Pharm. Sci. 91: 2539-2548
-
(2002)
J. Pharm. Sci.
, vol.91
, pp. 2539-2548
-
-
Deferme, S.1
Mols, R.2
Van Driessche, W.3
Augustijns, P.4
-
12
-
-
0033770782
-
In vitro evaluation of newly developed chalcone analogues in human cancer cells
-
De Vincenzo, R., Ferlini, C., Distefano, M., Gaggini, C., Riva, A., Bombardelli, E., Morazzoni, P., Valenti, P., Belluti, F., Ranelletti, F. O., Mancuso, S., Scambia, G. (2000) In vitro evaluation of newly developed chalcone analogues in human cancer cells. Cancer Chemother. Pharmacol. 46: 305-312
-
(2000)
Cancer Chemother. Pharmacol.
, vol.46
, pp. 305-312
-
-
De Vincenzo, R.1
Ferlini, C.2
Distefano, M.3
Gaggini, C.4
Riva, A.5
Bombardelli, E.6
Morazzoni, P.7
Valenti, P.8
Belluti, F.9
Ranelletti, F.O.10
Mancuso, S.11
Scambia, G.12
-
13
-
-
0037178587
-
The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextrometorphan: The role of gut CYP3A4 and P-glycoprotein
-
Di Marco, M. P., Edwards, D. J., Wainer, I. W., Ducharme, M. P. (2002) The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextrometorphan: The role of gut CYP3A4 and P-glycoprotein. Life Sci. 71: 1149-1160
-
(2002)
Life Sci.
, vol.71
, pp. 1149-1160
-
-
Di Marco, M.P.1
Edwards, D.J.2
Wainer, I.W.3
Ducharme, M.P.4
-
14
-
-
18244376403
-
Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters
-
Di Pietro, A., Conseil, G., Pérez-Victoria, J. M., Dayan, G., Baubichon-Cortay, H., Trompier, D., Steinfels, E., Jault, J.-M., De Wet, H., Maitrejean, M., Comte, G., Boumendjel, A., Mariotte, A.-M., Dumontet, C., McIntosh, D. B., Goffeau, A., Castanys, S., Gamarro, F., Barron, D. (2002) Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters. Cell. Mol. Life Sci. 59: 307-322
-
(2002)
Cell. Mol. Life Sci.
, vol.59
, pp. 307-322
-
-
Di Pietro, A.1
Conseil, G.2
Pérez-Victoria, J.M.3
Dayan, G.4
Baubichon-Cortay, H.5
Trompier, D.6
Steinfels, E.7
Jault, J.-M.8
De Wet, H.9
Maitrejean, M.10
Comte, G.11
Boumendjel, A.12
Mariotte, A.-M.13
Dumontet, C.14
McIntosh, D.B.15
Goffeau, A.16
Castanys, S.17
Gamarro, F.18
Barron, D.19
-
15
-
-
0034520267
-
St. John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4
-
Durr, D., Stieger, B., Kullak-Ublick, G. A., Rentsch, K. M., Steinert, H. C., Meier, P. J., Fattinger, K. (2000) St. John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4. Clin. Pharmacol. Ther. 68: 598-604
-
(2000)
Clin. Pharmacol. Ther.
, vol.68
, pp. 598-604
-
-
Durr, D.1
Stieger, B.2
Kullak-Ublick, G.A.3
Rentsch, K.M.4
Steinert, H.C.5
Meier, P.J.6
Fattinger, K.7
-
16
-
-
0032865554
-
Inhibition of the CYP3A4-mediated metabolism and P-glycoprotein-mediated transport of the HIV-1 protease inhibitor saquinavir by grapefruit juice components
-
Eagling, V. A., Profit, L., Back, D. J. (1999) Inhibition of the CYP3A4-mediated metabolism and P-glycoprotein-mediated transport of the HIV-1 protease inhibitor saquinavir by grapefruit juice components. Br. J. Clin. Pharmacol. 48: 543-552
-
(1999)
Br. J. Clin. Pharmacol.
, vol.48
, pp. 543-552
-
-
Eagling, V.A.1
Profit, L.2
Back, D.J.3
-
17
-
-
1442321728
-
6′,7′-Dihydroxybergamottin in grapefruit juice and Seville orange juice: Effects on cyclosporin disposition, enterocyte CYP3A4, and P-glycopotein
-
Edwards, D. J., Fitzsimmons, M. E., Schuetz, E., Yasuda, K., Ducharme, M. P., Warbasse, L. H., Woster, P. M., Schuetz, J. D., Watkins, P. (1999) 6′,7′-Dihydroxybergamottin in grapefruit juice and Seville orange juice: Effects on cyclosporin disposition, enterocyte CYP3A4, and P-glycopotein. Clin. Pharmacol. Ther. 65: 237-244
-
(1999)
Clin. Pharmacol. Ther.
, vol.65
, pp. 237-244
-
-
Edwards, D.J.1
Fitzsimmons, M.E.2
Schuetz, E.3
Yasuda, K.4
Ducharme, M.P.5
Warbasse, L.H.6
Woster, P.M.7
Schuetz, J.D.8
Watkins, P.9
-
18
-
-
0033973926
-
Influence of dietary components on the gastrointestinal metabolism and transport of drugs
-
Evans, A. M. (2000) Influence of dietary components on the gastrointestinal metabolism and transport of drugs. Ther. Drug Monitor. 22: 131-136
-
(2000)
Ther. Drug Monitor
, vol.22
, pp. 131-136
-
-
Evans, A.M.1
-
19
-
-
0032927254
-
Drug, meal and formulation interactions influencing drug absorption after oral administration
-
Fleisher, D., Cheng, L., Zhou, Y., Pao, L.-H., Karim, A. (1999) Drug, meal and formulation interactions influencing drug absorption after oral administration. Clin. Pharmacokinet. 36: 233-254
-
(1999)
Clin. Pharmacokinet.
, vol.36
, pp. 233-254
-
-
Fleisher, D.1
Cheng, L.2
Zhou, Y.3
Pao, L.-H.4
Karim, A.5
-
20
-
-
0033060635
-
Effects of a chargrilled meat diet on expression of CYP3A4, CYP1A and P-glycoprotein levels in healthy volunteers
-
Fontana, R. J., Lown, K. S., Paine, M. F., Fortlage, L., Santella, R. M., Felton, J. S., Knize, M. G., Greenberg, A., Watkins, P. B. (1999) Effects of a chargrilled meat diet on expression of CYP3A4, CYP1A and P-glycoprotein levels in healthy volunteers. Gastroenterology 117: 89-98
-
(1999)
Gastroenterology
, vol.117
, pp. 89-98
-
-
Fontana, R.J.1
Lown, K.S.2
Paine, M.F.3
Fortlage, L.4
Santella, R.M.5
Felton, J.S.6
Knize, M.G.7
Greenberg, A.8
Watkins, P.B.9
-
21
-
-
0035735338
-
An in vitro evaluation of human cytochrome P450 3A4 and P-glycoprotein inhibition by garlic
-
Foster, B. C., Foster, M. S., Vandenhoek, S., Krantis, A., Budzinski, J. W., Arnason, J. T., Gallicano, K. D., Choudri, S. (2001) An in vitro evaluation of human cytochrome P450 3A4 and P-glycoprotein inhibition by garlic. J. Pharm. Sci. 4: 176-184
-
(2001)
J. Pharm. Sci.
, vol.4
, pp. 176-184
-
-
Foster, B.C.1
Foster, M.S.2
Vandenhoek, S.3
Krantis, A.4
Budzinski, J.W.5
Arnason, J.T.6
Gallicano, K.D.7
Choudri, S.8
-
22
-
-
0033980182
-
P-glycoprotein: A defense mechanism limiting oral bioavailability and CNS accumulation of drugs
-
Fromm, M. F. (2000) P-glycoprotein: A defense mechanism limiting oral bioavailability and CNS accumulation of drugs. Int. J. Clin. Pharmacol. Ther. 38: 69-74
-
(2000)
Int. J. Clin. Pharmacol. Ther.
, vol.38
, pp. 69-74
-
-
Fromm, M.F.1
-
23
-
-
0035004474
-
Inhibitory potential of herbal medicines on human cytochrome P450-mediated oxidation: Properties of umbelliferous or citrus crude extracts and their relative prescriptions
-
Guo, L. Q., Taniguchi, M., Chen, Q. Y., Baba, K., Yamazoe, Y. (2001) Inhibitory potential of herbal medicines on human cytochrome P450-mediated oxidation: Properties of umbelliferous or citrus crude extracts and their relative prescriptions. Jpn. J. Pharmacol. 85: 399-408
-
(2001)
Jpn. J. Pharmacol.
, vol.85
, pp. 399-408
-
-
Guo, L.Q.1
Taniguchi, M.2
Chen, Q.Y.3
Baba, K.4
Yamazoe, Y.5
-
24
-
-
0026621245
-
ABC transporters: From microorganisms to man
-
Higgins, C. F. (1992) ABC transporters: From microorganisms to man. Annu. Rev. Cell. Biol. 8: 736-749
-
(1992)
Annu. Rev. Cell. Biol.
, vol.8
, pp. 736-749
-
-
Higgins, C.F.1
-
25
-
-
0033762552
-
Acute intoxication of cyclosporin caused by coadministration of decoctions of the fruits of Citrus Aurantium and the pericarps of Citrus Grandis
-
Hou, Y. C., Hsiu, S. L., Tsao, C. W., Wang, Y. H., Chao, P. D. (2000) Acute intoxication of cyclosporin caused by coadministration of decoctions of the fruits of Citrus Aurantium and the pericarps of Citrus Grandis. Planta Med. 66: 653-655
-
(2000)
Planta Med.
, vol.66
, pp. 653-655
-
-
Hou, Y.C.1
Hsiu, S.L.2
Tsao, C.W.3
Wang, Y.H.4
Chao, P.D.5
-
26
-
-
0034634749
-
Inhibition of P-glycoprotein by orange juice components, polymethoxyflavones in adriamycin-resistant human myelogenous leukemia (K562/ADM) cells
-
Ikegawa, T., Ushigome, F., Kyoabu, N., Morimoto, S., Shoyama, Y., Naito, M., Tsuruo, T., Ohtani, H., Sawada, Y. (2000) Inhibition of P-glycoprotein by orange juice components, polymethoxyflavones in adriamycin-resistant human myelogenous leukemia (K562/ADM) cells. Cancer Lett. 160: 21-28
-
(2000)
Cancer Lett.
, vol.160
, pp. 21-28
-
-
Ikegawa, T.1
Ushigome, F.2
Kyoabu, N.3
Morimoto, S.4
Shoyama, Y.5
Naito, M.6
Tsuruo, T.7
Ohtani, H.8
Sawada, Y.9
-
27
-
-
0036304016
-
Pharmacokinetic interactions between herbal remedies and medicinal drugs
-
Ioannides, C. (2002) Pharmacokinetic interactions between herbal remedies and medicinal drugs. Xenobiotica 32: 451-478
-
(2002)
Xenobiotica
, vol.32
, pp. 451-478
-
-
Ioannides, C.1
-
28
-
-
0037196568
-
Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols
-
Jodoin, J., Demeule, M., Béliveay, R. (2002) Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols. Biochim. Biophys. Acta 1542: 149-159
-
(2002)
Biochim. Biophys. Acta
, vol.1542
, pp. 149-159
-
-
Jodoin, J.1
Demeule, M.2
Béliveay, R.3
-
29
-
-
0000006828
-
Pharmacokinetic interaction of digoxin with a herbal extract from St John's wort (Hypericum perforatum)
-
Johne, A., Brockmoller, J., Bauer, S., Maurer, A., Langheinrich, M., Roots, I. (1999) Pharmacokinetic interaction of digoxin with a herbal extract from St John's wort (Hypericum perforatum). Clin. Pharmacol. Ther. 66: 338-345
-
(1999)
Clin. Pharmacol. Ther.
, vol.66
, pp. 338-345
-
-
Johne, A.1
Brockmoller, J.2
Bauer, S.3
Maurer, A.4
Langheinrich, M.5
Roots, I.6
-
30
-
-
0022931552
-
The effect of vehicle on the oral absorption of cyclosporin
-
Johnston, A., Marsden, J. T., Hla, K. K., Henry, J. A., Holt, D. W. (1986) The effect of vehicle on the oral absorption of cyclosporin. Br. J. Clin. Pharmacol. 21: 331-333
-
(1986)
Br. J. Clin. Pharmacol.
, vol.21
, pp. 331-333
-
-
Johnston, A.1
Marsden, J.T.2
Hla, K.K.3
Henry, J.A.4
Holt, D.W.5
-
31
-
-
0000063239
-
Severe gastrointestinal toxicity with concomitant ingestion of ritonavir and garlic
-
Laroche, M., Choudri, S., Gallicano, K., Foster, B. (1998) Severe gastrointestinal toxicity with concomitant ingestion of ritonavir and garlic. Can. J. Infectious Dis. Supp. 9: 471
-
(1998)
Can. J. Infectious Dis. Supp.
, vol.9
, pp. 471
-
-
Laroche, M.1
Choudri, S.2
Gallicano, K.3
Foster, B.4
-
32
-
-
0032896566
-
Comparison of effects of natural or artificial rodent diet on etoposide absorption in rats
-
Lo, Y. L., Huang, J. D. (1999) Comparison of effects of natural or artificial rodent diet on etoposide absorption in rats. In Vivo 13: 51-55
-
(1999)
In Vivo
, vol.13
, pp. 51-55
-
-
Lo, Y.L.1
Huang, J.D.2
-
33
-
-
0035145127
-
Seville orange juice-felodipine interaction: Comparison with dilute grapefruit juice and involvement of furocoumarins
-
Malhotra, S., Bailey, D. G., Paine, M. F., Watkins, P. B. (2001) Seville orange juice-felodipine interaction: Comparison with dilute grapefruit juice and involvement of furocoumarins. Clin. Pharmacol. Ther. 69: 14-23
-
(2001)
Clin. Pharmacol. Ther.
, vol.69
, pp. 14-23
-
-
Malhotra, S.1
Bailey, D.G.2
Paine, M.F.3
Watkins, P.B.4
-
34
-
-
0033637140
-
The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease and cancer
-
Middleton, E., Kandaswami, C., Theoharides, T. C. (2000) The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease and cancer. Pharmacol. Rev. 52: 673-751
-
(2000)
Pharmacol. Rev.
, vol.52
, pp. 673-751
-
-
Middleton, E.1
Kandaswami, C.2
Theoharides, T.C.3
-
35
-
-
0034600237
-
Effect of bioflavonoids on vincristine transport across blood-brain barrier
-
Mitsunaga Y., Takanaga, H., Matsuo, H., Naito, M., Tsuruo, T., Ohtani, H., Sawada, Y. (2000) Effect of bioflavonoids on vincristine transport across blood-brain barrier. Eur. J. Pharmacol. 395: 193-201
-
(2000)
Eur. J. Pharmacol.
, vol.395
, pp. 193-201
-
-
Mitsunaga, Y.1
Takanaga, H.2
Matsuo, H.3
Naito, M.4
Tsuruo, T.5
Ohtani, H.6
Sawada, Y.7
-
36
-
-
0033374904
-
Antimutagenic activity of polymethoxyflavonoids from Citrus aurantium
-
Miyazawa, M., Okuno, Y., Fukuyama, M., Nakamura, S., Kosaka, H. (1999) Antimutagenic activity of polymethoxyflavonoids from Citrus aurantium. J. Agric. Food Chem. 47: 5239-5244
-
(1999)
J. Agric. Food Chem.
, vol.47
, pp. 5239-5244
-
-
Miyazawa, M.1
Okuno, Y.2
Fukuyama, M.3
Nakamura, S.4
Kosaka, H.5
-
37
-
-
0034762396
-
Biological activity of a fruit vegetable, "Anastasia green", a species of sweet pepper
-
Motohashi, N., Kurihara, T., Wakabayashi, H., Yaji, M., Mucsi, I., Molnar, J., Maruyama, S., Sakagami, H., Nakashima, H., Tani, S., Shirataki, Y., Kawase, M. (2001) Biological activity of a fruit vegetable, "Anastasia green", a species of sweet pepper. In Vivo 15: 437-442
-
(2001)
In Vivo
, vol.15
, pp. 437-442
-
-
Motohashi, N.1
Kurihara, T.2
Wakabayashi, H.3
Yaji, M.4
Mucsi, I.5
Molnar, J.6
Maruyama, S.7
Sakagami, H.8
Nakashima, H.9
Tani, S.10
Shirataki, Y.11
Kawase, M.12
-
38
-
-
0033913305
-
Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4
-
Ohnishi, A., Matsuo, H., Yamada, S., Takanaga, H., Morimoto, S., Shoyama, Y., Ohtani, H., Sawada, Y. (2000) Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4. Br. J. Pharmacol. 130: 1369-1377
-
(2000)
Br. J. Pharmacol.
, vol.130
, pp. 1369-1377
-
-
Ohnishi, A.1
Matsuo, H.2
Yamada, S.3
Takanaga, H.4
Morimoto, S.5
Shoyama, Y.6
Ohtani, H.7
Sawada, Y.8
-
39
-
-
0035671937
-
Saint John's wort: An in vitro analysis of P-glycoprotein induction due to extended exposure
-
Perloff, M. D., Von Moltke, L. L., Störmer, E., Shader, R. I., Greenblatt, D. J. (2001) Saint John's wort: An in vitro analysis of P-glycoprotein induction due to extended exposure. Br. J. Pharmacol. 134: 1601-1608
-
(2001)
Br. J. Pharmacol.
, vol.134
, pp. 1601-1608
-
-
Perloff, M.D.1
Von Moltke, L.L.2
Störmer, E.3
Shader, R.I.4
Greenblatt, D.J.5
-
40
-
-
0034639643
-
Indinavir concentrations and St John's Wort
-
Piscitelli, S. C., Burnstein, A. H., Chiatt, D., Alfaro, R. M., Falloon, J. (2000) Indinavir concentrations and St John's Wort. Lancet 355: 547-548
-
(2000)
Lancet
, vol.355
, pp. 547-548
-
-
Piscitelli, S.C.1
Burnstein, A.H.2
Chiatt, D.3
Alfaro, R.M.4
Falloon, J.5
-
41
-
-
0032828093
-
Inhibition of P-glycoprotein activity and reversal of multidrug resistance in vitro by rosemary extract
-
Plouzek, C. A., Ciolino, H. P., Clarke, R., Yeh, G. C. (1999) Inhibition of P-glycoprotein activity and reversal of multidrug resistance in vitro by rosemary extract. Eur. J. Cancer 35: 1541-1545
-
(1999)
Eur. J. Cancer
, vol.35
, pp. 1541-1545
-
-
Plouzek, C.A.1
Ciolino, H.P.2
Clarke, R.3
Yeh, G.C.4
-
42
-
-
0032055794
-
Effects of elevated viscosity in the upper gastrointestinal tract on drug absorption in dogs
-
Reppas, C., Eleftheriou, G., Macheras, P. Symillides, M., Dressman, J. B. (1998) Effects of elevated viscosity in the upper gastrointestinal tract on drug absorption in dogs. Eur. J. Pharm. Sci. 6: 131-139
-
(1998)
Eur. J. Pharm. Sci.
, vol.6
, pp. 131-139
-
-
Reppas, C.1
Eleftheriou, G.2
Macheras, P.3
Symillides, M.4
Dressman, J.B.5
-
43
-
-
0034639638
-
Acute heart transplant rejection due to Saint John's wort
-
Ruschitzka, F., Meijer, P. J., Turina, M., Luscher, T. F., Noll, G. (2000) Acute heart transplant rejection due to Saint John's wort. Lancet 355: 548-549
-
(2000)
Lancet
, vol.355
, pp. 548-549
-
-
Ruschitzka, F.1
Meijer, P.J.2
Turina, M.3
Luscher, T.F.4
Noll, G.5
-
44
-
-
0033863355
-
Dietary intake and bioavailability of polyphenols
-
Scalbert, A., Williamson, G. (2000) Dietary intake and bioavailability of polyphenols. J. Nutr. 130: 2073S-2085S.
-
(2000)
J. Nutr.
, vol.130
-
-
Scalbert, A.1
Williamson, G.2
-
45
-
-
0027981909
-
Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-gp as a possible target
-
Scambia, G., Ranelletti, F. O., Panici, P. B., De Vincenzo, R., Bonanno, G., Ferrandina, G., Piantelli, M., Bussa, S., Rumi, C., Cianfriglia, M. (1994) Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-gp as a possible target. Cancer Chemother. Pharmacol. 34: 459-464
-
(1994)
Cancer Chemother. Pharmacol.
, vol.34
, pp. 459-464
-
-
Scambia, G.1
Ranelletti, F.O.2
Panici, P.B.3
De Vincenzo, R.4
Bonanno, G.5
Ferrandina, G.6
Piantelli, M.7
Bussa, S.8
Rumi, C.9
Cianfriglia, M.10
-
46
-
-
4243801613
-
Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug transporting) P-glycoproteins
-
Schinkel, A. H., Mayer, U., Wagenaar, E., Mol, C. A., Van Deemter, L., Smit, J. J., Van Der Valk, M. A., Voordouw, A. C., Spits, H., Van Tellingen, O., Zijlmans, J. M., Fibbe, W. E., Borst, P. (1997) Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug transporting) P-glycoproteins. Proc. Natl Acad. Sci. USA 94: 4028-4033
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 4028-4033
-
-
Schinkel, A.H.1
Mayer, U.2
Wagenaar, E.3
Mol, C.A.4
Van Deemter, L.5
Smit, J.J.6
Van Der Valk, M.A.7
Voordouw, A.C.8
Spits, H.9
Van Tellingen, O.10
Zijlmans, J.M.11
Fibbe, W.E.12
Borst, P.13
-
47
-
-
0033984216
-
Altered expression of hepatic cytochromes P-450 in mice deficient in one or more mdr1 genes
-
Schuetz, E. G., Umbenhauer, D. R., Yasuda, K., Brimer, C., Nguyen, L., Relling, M. V., Schuetz, J. D., Schinkel, A. H. (2000) Altered expression of hepatic cytochromes P-450 in mice deficient in one or more mdr1 genes. Mol. Pharmacol. 57: 188-197
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 188-197
-
-
Schuetz, E.G.1
Umbenhauer, D.R.2
Yasuda, K.3
Brimer, C.4
Nguyen, L.5
Relling, M.V.6
Schuetz, J.D.7
Schinkel, A.H.8
-
48
-
-
0031581819
-
Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein
-
Shapiro, A. B., Ling, V. (1997) Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein. Biochem. Pharmacol. 53: 587-596
-
(1997)
Biochem. Pharmacol.
, vol.53
, pp. 587-596
-
-
Shapiro, A.B.1
Ling, V.2
-
49
-
-
0032883045
-
Effects of food on clinical pharmacokinetics
-
Singh, B. N. (1999) Effects of food on clinical pharmacokinetics. Clin. Pharmacokinet. 37: 213-255
-
(1999)
Clin. Pharmacokinet.
, vol.37
, pp. 213-255
-
-
Singh, B.N.1
-
50
-
-
0032904977
-
Grapefruit juice activates P-glycoprotein-mediated drug transport
-
Soldner, A., Christiaens, U., Susanto, M., Wacher, V. J., Silverman, J. A., Benet, L. Z. (1999) Grapefruit juice activates P-glycoprotein-mediated drug transport. Pharm. Res. 16: 478-485
-
(1999)
Pharm. Res.
, vol.16
, pp. 478-485
-
-
Soldner, A.1
Christiaens, U.2
Susanto, M.3
Wacher, V.J.4
Silverman, J.A.5
Benet, L.Z.6
-
51
-
-
0035108539
-
Grapefruit juice enhances intestinal absorption of the P-glycoprotein substrate talinolol
-
Spahn-Langguth, H., Langguth, P. (2001) Grapefruit juice enhances intestinal absorption of the P-glycoprotein substrate talinolol. Eur. J. Pharm. Sci. 12: 361-367
-
(2001)
Eur. J. Pharm. Sci.
, vol.12
, pp. 361-367
-
-
Spahn-Langguth, H.1
Langguth, P.2
-
52
-
-
0031962002
-
P-glycoprotein transporters in the intestinal tract: Evaluation of the potential in vivo relevance of in vitro data employing talinolol as a model compound
-
Spahn-Langguth, H., Baktir, G., Radschuweit, A., Okyar, A., Terhaag, B., Ader, P., Hanafy, A., Langguth, P. (1998) P-glycoprotein transporters in the intestinal tract: Evaluation of the potential in vivo relevance of in vitro data employing talinolol as a model compound. Int. J. Clin. Pharmacol. Ther. 36: 16-24
-
(1998)
Int. J. Clin. Pharmacol. Ther.
, vol.36
, pp. 16-24
-
-
Spahn-Langguth, H.1
Baktir, G.2
Radschuweit, A.3
Okyar, A.4
Terhaag, B.5
Ader, P.6
Hanafy, A.7
Langguth, P.8
-
53
-
-
0031790854
-
Inhibition of vinblastine efflux mediated by P-glycoprotein by grapefruit juice components in Caco-2 cells
-
Takanaga, H., Ohnishi, A., Matsuo, H., Sawada, Y. (1998) Inhibition of vinblastine efflux mediated by P-glycoprotein by grapefruit juice components in Caco-2 cells. Biol. Pharm. Bull. 21: 1062-1066
-
(1998)
Biol. Pharm. Bull.
, vol.21
, pp. 1062-1066
-
-
Takanaga, H.1
Ohnishi, A.2
Matsuo, H.3
Sawada, Y.4
-
54
-
-
0034029597
-
Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P540 3A4
-
Takanaga, H., Ohnishi, A., Yamada, S., Matsuo, H., Morimoto, S., Shoyama, Y., Ohtani, H., Sawada, Y. (2000) Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P540 3A4. J. Pharmacol. Exp. Ther. 293: 230-236
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.293
, pp. 230-236
-
-
Takanaga, H.1
Ohnishi, A.2
Yamada, S.3
Matsuo, H.4
Morimoto, S.5
Shoyama, Y.6
Ohtani, H.7
Sawada, Y.8
-
55
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
Thiebaut, F., Tsuruo, T, Hamada, H., Gottesman, M. M., Pastan, I., Willingham, M. C. (1987) Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc. Natl Acad. Sci. USA 84: 7735-7738
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
56
-
-
0036288273
-
Effects of grapefruit juice and orange juice on the intestinal efflux of P-glycoprotein substrates
-
Tian, R., Koyabu, N., Takanaga, H., Matsuo, H., Ohtani, H., Sawada, Y. (2002) Effects of grapefruit juice and orange juice on the intestinal efflux of P-glycoprotein substrates. Pharm. Res. 19: 802-809
-
(2002)
Pharm. Res.
, vol.19
, pp. 802-809
-
-
Tian, R.1
Koyabu, N.2
Takanaga, H.3
Matsuo, H.4
Ohtani, H.5
Sawada, Y.6
-
57
-
-
4243222178
-
Effect of flavonoids on P-gp mediated transport in a human breast cancer cell line
-
Tseng, E., Liang, W., Wallen, C., Morris, M. E. (2001) Effect of flavonoids on P-gp mediated transport in a human breast cancer cell line. AAPS PharmSci 3: S2081
-
(2001)
AAPS PharmSci
, vol.3
-
-
Tseng, E.1
Liang, W.2
Wallen, C.3
Morris, M.E.4
-
58
-
-
0034990957
-
St. John's wort: A hidden risk for transplant patients
-
Turton-Weeks, S. M., Barone, G. W., Gurley, B. J., Ketel, B. L., Lightfoot, M. L., Abul-Ezz, S. R. (2001) St. John's wort: A hidden risk for transplant patients. Prog. Transplant. 11: 116-120
-
(2001)
Prog. Transplant.
, vol.11
, pp. 116-120
-
-
Turton-Weeks, S.M.1
Barone, G.W.2
Gurley, B.J.3
Ketel, B.L.4
Lightfoot, M.L.5
Abul-Ezz, S.R.6
-
59
-
-
0036326062
-
Intestinal absorption enhancement of the ester prodrug tenofovir disoproxil fumarate through modulation of the biochemical barrier by defined ester mixtures
-
Van Gelder, J., Deferme, S., Naesens, L., De Clercq, E., Van Den Mooter, G., Kinget, R., Augustijns, P. (2002) Intestinal absorption enhancement of the ester prodrug tenofovir disoproxil fumarate through modulation of the biochemical barrier by defined ester mixtures. Drug Metab. Dispos. 30: 924-930
-
(2002)
Drug Metab. Dispos.
, vol.30
, pp. 924-930
-
-
Van Gelder, J.1
Deferme, S.2
Naesens, L.3
De Clercq, E.4
Van Den Mooter, G.5
Kinget, R.6
Augustijns, P.7
-
60
-
-
0035997895
-
Effect of dietary fatty acids on the intestinal permeability of marker drug compounds in excised rat jejunum
-
Vine, D. F., Charman, S. A., Gibson, P. R., Sinclair, A. J., Porter, C. J. (2002) Effect of dietary fatty acids on the intestinal permeability of marker drug compounds in excised rat jejunum. J. Pharm. Pharmacol. 54: 809-819
-
(2002)
J. Pharm. Pharmacol.
, vol.54
, pp. 809-819
-
-
Vine, D.F.1
Charman, S.A.2
Gibson, P.R.3
Sinclair, A.J.4
Porter, C.J.5
-
61
-
-
0036141738
-
Peppemint oil enhances cyclosporin oral bioavailability in rats: Comparison with D-a-tocopheryl poly(ethylene glycol 1000) succinate (TPGS) and ketoconazole
-
Wacher, V. J., Wong, S., Wong, H. T. (2001) Peppemint oil enhances cyclosporin oral bioavailability in rats: Comparison with D-a-tocopheryl poly(ethylene glycol 1000) succinate (TPGS) and ketoconazole. J. Pharm. Sci. 91: 77-90
-
(2001)
J. Pharm. Sci.
, vol.91
, pp. 77-90
-
-
Wacher, V.J.1
Wong, S.2
Wong, H.T.3
-
62
-
-
0035478718
-
Intestinal drug efflux: Formulation and food effects
-
Wagner, D., Spahn-Langguth, H., Hanafy, A., Koggel, A., Langguth, P. (2001) Intestinal drug efflux: Formulation and food effects. Adv. Drug Deliv. Rev. 50: S13-S31
-
(2001)
Adv. Drug Deliv. Rev.
, vol.50
-
-
Wagner, D.1
Spahn-Langguth, H.2
Hanafy, A.3
Koggel, A.4
Langguth, P.5
-
63
-
-
0034954793
-
Inhibition of P-glycoprotein transport function by grapefruit juice psoralen
-
Wang, E., Casciano, C. N., Clement, R. P., Johnson, W. W. (2001a) Inhibition of P-glycoprotein transport function by grapefruit juice psoralen. Pharm. Res. 18: 432-438
-
(2001)
Pharm. Res.
, vol.18
, pp. 432-438
-
-
Wang, E.1
Casciano, C.N.2
Clement, R.P.3
Johnson, W.W.4
-
64
-
-
0034748331
-
The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity
-
Wang, Z., Gorski, C., Hamman, M. A., Huang, S.-M., Lesko, L. J., Hall, S. D. (2001b) The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity. Clin. Pharmacol. Ther. 70: 317-326
-
(2001)
Clin. Pharmacol. Ther.
, vol.70
, pp. 317-326
-
-
Wang, Z.1
Gorski, C.2
Hamman, M.A.3
Huang, S.-M.4
Lesko, L.J.5
Hall, S.D.6
-
65
-
-
0029825085
-
Effects of food on drug absorption
-
Welling, P. G. (1996) Effects of food on drug absorption. Annu Rev. Nutr. 16: 383-415
-
(1996)
Annu Rev. Nutr.
, vol.16
, pp. 383-415
-
-
Welling, P.G.1
-
66
-
-
0032951089
-
Transport of Rhodamine 123, a P-glycoprotein substrate, across rat intestine and Caco-2 cell monolayers in the presence of cytochrome P450 3A-related compounds
-
Yumoto, R., Murakami, T., Nakamoto, Y., Hasegawa, R., Nagai, J., Takano, M. (1999) Transport of Rhodamine 123, a P-glycoprotein substrate, across rat intestine and Caco-2 cell monolayers in the presence of cytochrome P450 3A-related compounds. J. Pharmacol. Exp. Ther. 289: 149-155
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.289
, pp. 149-155
-
-
Yumoto, R.1
Murakami, T.2
Nakamoto, Y.3
Hasegawa, R.4
Nagai, J.5
Takano, M.6
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